Mineralys TherapeuticsMLYS
13F holders, Q4 2024 (December 31)At the end of Q4 2024, 108 institutions reported holding Mineralys Therapeutics Inc. (MLYS) in their 13F filings, up 2 from Q3 2024. 13 opened new positions and 14 sold out. The largest holders were Catalys Pacific, LLC ($106.4M), Samsara Biocapital, LLC ($62.5M) and Ra Capital Management, L.P. ($59.7M). 2 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).
- Company
- Mineralys Therapeutics Inc.
- CUSIP
- 603170101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2024 → Q4 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 13 | $9.7M |
| Exits | 14 | $12.3M |
All 13F filers, Q3 2024 → Q4 2024: 4,027,287 shares bought and 2,021,581 shares sold, net +2,005,706 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 108 holders
| Catalys Pacific, LLC | 91.82% | No change | 8,644,579 | $106.4M |
| Samsara Biocapital, LLC | 8.57% | No change | 5,074,916 | $62.5M |
| Ra Capital Management, L.P. | 0.80% | No change | 4,850,984 | $59.7M |
| TCG Crossover Management, LLC | 2.97% | No change | 2,470,265 | $30.4M |
| BlackRock, Inc. | 0.00% | Reduce -0.3% | 2,138,522 | $26.3M |
| SR One Capital Management, LP | 6.05% | No change | 2,016,822 | $24.8M |
| Franklin Resources Inc. | 0.01% | Add +0.0% | 1,745,597 | $21.5M |
| Orbimed Advisors LLC | 0.41% | Reduce -19.5% | 1,611,637 | $19.8M |
| Vanguard Group Inc. | 0.00% | Add +5.0% | 1,432,042 | $17.6M |
| Laurion Capital Management LP | 1.11% | No change | 1,412,389 | $17.4M |
| Adams Street Partners LLC | 12.33% | Reduce -26.3% | 1,129,807 | $13.9M |
| Millennium Management | 0.01% | Add +1015.8% | 1,101,674 | $13.6M |
| Jennison Associates LLC | 0.01% | Add +55.4% | 1,082,006 | $13.3M |
| Caligan Partners LP | 3.15% | Add +3.1% | 1,011,155 | $12.4M |
| Integral Health Asset Management, LLC | 0.95% | Add +145.8% | 875,000 | $10.8M |
| American Century Companies Inc. | 0.01% | Reduce -8.9% | 848,630 | $10.4M |
| ADAR1 Capital Management, LLC | 2.21% | Add +15.4% | 841,541 | $10.4M |
| Boothbay Fund Management, LLC | 0.25% | Add +7.3% | 650,023 | $8.0M |
| Nantahala Capital Management, LLC | 0.54% | No change | 632,506 | $7.8M |
| Geode Capital Management, LLC | 0.00% | Reduce -0.1% | 620,033 | $7.6M |
| Morgan Stanley | 0.00% | Add +14.3% | 589,444 | $7.3M |
| State Street Corp. | 0.00% | Add +4.3% | 504,533 | $6.2M |
| JPMorgan Chase & Co. | 0.00% | Add +2251.5% | 503,590 | $6.2M |
| Stempoint Capital LP | 1.24% | New | 400,101 | $4.9M |
| Sectoral Asset Management Inc. | 3.13% | Add +15.6% | 380,883 | $4.7M |
| Affinity Asset Advisors, LLC | 0.73% | No change | 350,000 | $4.3M |
| Ikarian Capital, LLC | 1.17% | Add +84.7% | 332,390 | $4.1M |
| Candriam S.C.A. | 0.02% | New | 305,272 | $3.8M |
| FMR LLC | 0.00% | Add +0.1% | 304,184 | $3.7M |
| Northern Trust Corp. | 0.00% | Add +0.7% | 246,113 | $3.0M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +0.6% | 214,906 | $2.6M |
| Sphera Funds Management LTD. | 0.43% | Reduce -30.0% | 190,672 | $2.3M |
| DAFNA Capital Management LLC | 0.46% | No change | 146,500 | $1.8M |
| Pale Fire Capital SE | 0.39% | No change | 136,897 | $1.7M |
| Prudential Financial Inc. | 0.00% | Add +85.7% | 125,650 | $1.5M |
| Renaissance Technologies | 0.00% | Add +15.1% | 119,500 | $1.5M |
| Goldman Sachs Group Inc. | 0.00% | Add +25.1% | 111,915 | $1.4M |
| Bank of America Corp. | 0.00% | Add +12.0% | 107,703 | $1.3M |
| Polar Asset Management Partners Inc. | 0.02% | Add +144.7% | 99,100 | $1.2M |
| Wellington Management Group LLP | 0.00% | Add +43.0% | 91,529 | $1.1M |
| Tema ETFs LLC | 0.46% | — | 89,529 | $1.1M |
| NEOS Investment Management LLC | 0.03% | Reduce -27.5% | 89,529 | $1.1M |
| Lion Point Capital, LP | 5.09% | No change | 79,000 | $972K |
| Nuveen Asset Management, LLC | 0.00% | No change | 67,877 | $836K |
| Bank of New York Mellon Corp | 0.00% | Add +2.7% | 65,318 | $804K |
| UBS Group AG | 0.00% | Add +203.6% | 48,885 | $602K |
| Barclays PLC | 0.00% | Add +21.4% | 46,396 | $571K |
| Rhumbline Advisers | 0.00% | Add +1.7% | 40,556 | $499K |
| Alps Advisors Inc. | 0.00% | Add +5.2% | 40,248 | $495K |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0.01% | Reduce -9.7% | 28,068 | $346K |
| STRS Ohio | 0.00% | No change | 26,900 | $331K |
| Deutsche Bank AG | 0.00% | Add +62.3% | 26,732 | $329K |
| Wells Fargo & Company | 0.00% | Add +19.1% | 23,714 | $292K |
| Citigroup Inc. | 0.00% | Add +6.3% | 23,364 | $288K |
| Alliancebernstein L.P. | 0.00% | Add +0.3% | 23,024 | $283K |
| SG Americas Securities, LLC | 0.00% | Add +119.0% | 19,961 | $246K |
| Balyasny Asset Management L.P. | 0.00% | New | 17,786 | $219K |
| MetLife Investment Management, LLC | 0.00% | No change | 17,124 | $211K |
| Letko, Brosseau & Associates Inc. | 0.00% | Add +44.7% | 16,500 | $203K |
| Bellevue Group AG | 0.00% | No change | 16,499 | $203K |
| Dimensional Fund Advisors LP | 0.00% | New | 16,412 | $202K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +4.4% | 16,383 | $202K |
| Federated Hermes, Inc. | 0.00% | Reduce -7.9% | 15,516 | $191K |
| AlphaQuest LLC | 0.02% | Add +2637.8% | 15,222 | $187K |
| Martingale Asset Management L P | 0.00% | No change | 14,965 | $184K |
| Corebridge Financial, Inc. | 0.00% | Reduce -7.0% | 14,197 | $175K |
| EntryPoint Capital, LLC | 0.06% | New | 12,487 | $154K |
| Susquehanna International Group, LLP | 0.00% | New | 12,346 | $152K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -2.9% | 11,797 | $145K |
| T. Rowe Price Associates Inc. | 0.00% | New | 11,715 | $145K |
| CreativeOne Wealth, LLC | 0.00% | No change | 10,750 | $132K |
| China Universal Asset Management Co., Ltd. | 0.01% | Add +10.3% | 10,553 | $130K |
| ProShare Advisors LLC | 0.00% | New | 10,405 | $128K |
| New York State Common Retirement Fund | 0.00% | No change | 7,764 | $96K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | — | 7,136 | $88K |
| Virtus Advisers, LLC | 0.03% | Reduce -19.6% | 5,842 | $72K |
| Cwm, LLC | 0.00% | Add +0.3% | 5,237 | $64K |
| BNP Paribas Financial Markets | 0.00% | New | 3,895 | $48K |
| Royal Bank of Canada | 0.00% | Add +23.0% | 3,535 | $43K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 2,798 | $34K |
| Legal & General Group Plc | 0.00% | No change | 2,582 | $32K |
| PNC Financial Services Group, Inc. | 0.00% | Reduce -1.2% | 2,185 | $27K |
| California State Teachers Retirement System | 0.00% | No change | 2,069 | $25K |
| Smartleaf Asset Management LLC | 0.00% | Add +23.9% | 1,905 | $24K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Reduce -7.8% | 1,658 | $21K |
| GeoWealth Management, LLC | 0.00% | No change | 1,439 | $18K |
| Meeder Asset Management Inc. | 0.00% | New | 1,338 | $16K |
| GF Fund Management Co. LTD. | 0.00% | — | 1,045 | $13K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -62.4% | 1,005 | $12K |
| Sterling Capital Management LLC | 0.00% | Add +839.0% | 723 | $9K |
| Amalgamated Bank | 0.00% | No change | 682 | $8K |
| Comerica Bank | 0.00% | No change | 644 | $8K |
| SBI Securities Co., Ltd. | 0.00% | — | 400 | $5K |
| Simplex Trading, LLC | 0.00% | Add +10.9% | 337 | $4K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | No change | 319 | $4K |
| Daiwa Securities Group Inc. | 0.00% | No change | 152 | $2K |
| Quadrant Capital Group LLC | 0.00% | No change | 129 | $2K |
| Arax Advisory Partners | 0.00% | No change | 108 | $1K |
| Rothschild Investment LLC | 0.00% | Add +250.0% | 105 | $1K |
| Nisa Investment Advisors, LLC | 0.00% | Add +1960.0% | 103 | $1K |
"% of holder's portfolio" is MLYS's weight in each manager's 13F, not the share of Mineralys Therapeutics Inc. the manager owns.