Nautilus BiotechnologyNAUT

13F holders, Q3 2025 (September 30)
68holders −3
8new positions
12sold out
3famous investors
$0.84avg. 13F price*

At the end of Q3 2025, 68 institutions reported holding Nautilus Biotechnology Inc. (NAUT) in their 13F filings, down 3 from Q2 2025. 8 opened new positions and 12 sold out. The largest holders were a16z Capital Management, L.L.C. ($14.9M), Perceptive Advisors LLC ($10.6M) and Cercano Management LLC ($6.1M). 3 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).

Company
Nautilus Biotechnology Inc.
CUSIP
63909J108
Latest filing quarter
Q2 2026

History

Number of 13F holders

020406080100 Q1 2024: 73Q1 2024Q2 2024: 77Q2 2024Q3 2024: 83Q3 2024Q4 2024: 88Q4 2024Q1 2025: 88Q1 2025Q2 2025: 71Q2 2025Q3 2025: 68Q3 2025Q4 2025: 68Q4 2025Q1 2026: 81Q1 2026Q2 2026: 93Q2 2026

Total Exit/New Position Q2 2025 → Q3 2025

InstitutionsTotal Value
New Positions8$175K
Exits12$1.1M

All 13F filers, Q2 2025 → Q3 2025: 1,152,294 shares bought and 3,025,337 shares sold, net −1,873,043 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 68 holders

a16z Capital Management, L.L.C. 1.07% No change 17,653,917 $14.9M
Perceptive Advisors LLC 0.31% No change 12,594,211 $10.6M
Cercano Management LLC 0.23% No change 7,172,985 $6.1M
Madrona Venture Group, LLC 36.76% No change 6,020,770 $5.1M
Vanguard Group Inc. 0.00% Reduce -2.1% 2,431,829 $2.1M
Comprehensive Financial Management LLC 0.05% No change 2,207,619 $1.9M
Amazon Com Inc. 0.05% No change 1,457,055 $1.2M
Clarius Group, LLC 0.06% Add +14.1% 1,209,646 $1.0M
Renaissance Technologies 0.00% Add +62.5% 1,007,662 $851K
Millennium Management 0.00% Reduce -8.4% 967,548 $817K
Tikvah Management LLC 0.18% No change 726,895 $614K
Geode Capital Management, LLC 0.00% No change 553,602 $468K
Dimensional Fund Advisors LP 0.00% Reduce -33.8% 364,675 $308K
Corient Private Wealth LP 0.00% Reduce -26.7% 319,140 $270K
Jacobs Levy Equity Management, Inc. 0.00% Add +18.1% 301,012 $254K
Gsa Capital Partners LLP 0.02% Add +46.5% 259,203 $219K
Citadel Advisors 0.00% Add +42.7% 254,161 $215K
Alyeska Investment Group, L.P. 0.00% No change 253,468 $214K
Acadian Asset Management LLC 0.00% Add +251.5% 243,273 $203K
BlackRock, Inc. 0.00% Reduce -68.0% 201,444 $170K
Hillman Co. 0.05% No change 200,000 $169K
State Street Corp. 0.00% Reduce -1.6% 178,755 $151K
Jane Street Group, LLC 0.00% Reduce -49.0% 148,188 $125K
Crewe Advisors LLC 0.01% New 136,052 $115K
Squarepoint Ops LLC 0.00% Add +29.5% 131,827 $111K
Bridgeway Capital Management, LLC 0.00% No change 125,000 $106K
Northern Trust Corp. 0.00% Reduce -20.6% 117,836 $100K
Goldman Sachs Group Inc. 0.00% Reduce -62.6% 117,716 $99K
Qube Research & Technologies Ltd 0.00% Reduce -16.9% 51,667 $44K
Barclays PLC 0.00% Reduce -16.9% 48,254 $41K
HSBC Holdings PLC 0.00% No change 49,598 $40K
XTX Topco Ltd 0.00% Reduce -30.9% 45,724 $39K
Ashton Thomas Private Wealth, LLC 0.00% New 45,000 $38K
Fayez Sarofim & Co 0.00% No change 45,000 $38K
Palumbo Wealth Management LLC 0.01% Add +1.1% 42,117 $36K
Presidio Capital Management, LLC 0.01% No change 34,664 $29K
Badgley Phelps Wealth Managers, LLC 0.00% No change 30,000 $25K
Morgan Stanley 0.00% Reduce -52.9% 25,728 $22K
Virtu Financial LLC 0.00% New 19,683 $17K
Point72 Asia (Singapore) Pte. Ltd. 0.00% Reduce -50.0% 16,271 $14K
Callan Family Office, LLC 0.00% Reduce -69.7% 14,830 $13K
Caprock Group, LLC 0.00% — 17,090 $12K
Vanguard Capital Wealth Advisors 0.01% Reduce -15.6% 13,500 $11K
FNY Investment Advisers, LLC 0.00% No change 14,000 $11K
FMR LLC 0.00% Reduce -64.7% 8,660 $7K
Tower Research Capital LLC (TRC) 0.00% Reduce -74.0% 5,603 $5K
Rockefeller Capital Management L.P. 0.00% New 5,000 $4K
JPMorgan Chase & Co. 0.00% Reduce -8.8% 2,121 $2K
BNP Paribas Financial Markets 0.00% Reduce -57.3% 1,465 $1K
Royal Bank of Canada 0.00% Reduce -20.9% 1,822 $1K
TD Waterhouse Canada Inc. 0.00% No change 1,000 $830
Citigroup Inc. 0.00% Reduce -80.8% 884 $747
Bank of America Corp. 0.00% Reduce -90.3% 813 $686
Point72 (DIFC) Ltd 0.00% No change 789 $667
Osaic Holdings, Inc. 0.00% No change 715 $585
Wells Fargo & Company 0.00% Reduce -61.2% 560 $473
UBS Group AG 0.00% Reduce -97.1% 470 $397
Guerra Advisors Inc 0.00% New 400 $338
Aventura Private Wealth, LLC 0.00% No change 350 $296
EverSource Wealth Advisors, LLC 0.00% Reduce -39.4% 229 $193
Your Advocates Ltd., LLP 0.00% No change 150 $126
Arax Advisory Partners 0.00% New 148 $125
Optiver Holding B.V. 0.00% New 40 $34
True Wealth Design, LLC 0.00% Reduce -88.4% 17 $15
Cubist Systematic Strategies, LLC 0.00% Reduce -100.0% 1 $1
Cwm, LLC 0.00% Reduce -93.9% 182 $0
Covestor Ltd 0.00% No change 8 $0
Cloud Capital Management, LLC 0.00% New 49 $0

"% of holder's portfolio" is NAUT's weight in each manager's 13F, not the share of Nautilus Biotechnology Inc. the manager owns.