Nautilus BiotechnologyNAUT
13F holders, Q4 2025 (December 31)68holders
11new positions
7sold out
3famous investors
$1.95avg. 13F price*
At the end of Q4 2025, 68 institutions reported holding Nautilus Biotechnology Inc. (NAUT) in their 13F filings, unchanged from Q3 2025. 11 opened new positions and 7 sold out. The largest holders were a16z Capital Management, L.L.C. ($34.4M), Perceptive Advisors LLC ($24.6M) and Cercano Management LLC ($14.0M). 3 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Steve Cohen (0.0% of Point72 Asset Management's portfolio).
- Company
- Nautilus Biotechnology Inc.
- CUSIP
- 63909J108
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 11 | $2.4M |
| Exits | 7 | $471K |
All 13F filers, Q3 2025 → Q4 2025: 2,306,587 shares bought and 1,892,537 shares sold, net +414,050 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 68 holders
| a16z Capital Management, L.L.C. | 2.18% | No change | 17,653,917 | $34.4M |
| Perceptive Advisors LLC | 0.45% | No change | 12,594,211 | $24.6M |
| Cercano Management LLC | 0.53% | No change | 7,172,985 | $14.0M |
| Madrona Venture Group, LLC | 53.24% | No change | 6,020,770 | $11.7M |
| Vanguard Group Inc. | 0.00% | Add +6.8% | 2,598,223 | $5.1M |
| Comprehensive Financial Management LLC | 0.13% | No change | 2,207,619 | $4.3M |
| Amazon Com Inc. | 0.08% | No change | 1,457,055 | $2.8M |
| Clarius Group, LLC | 0.13% | No change | 1,209,646 | $2.4M |
| Millennium Management | 0.00% | Add +5.4% | 1,019,996 | $2.0M |
| Sentinel Trust Co. Lba | 0.14% | New | 750,000 | $1.5M |
| Tikvah Management LLC | 0.38% | No change | 726,895 | $1.4M |
| Acadian Asset Management LLC | 0.00% | Add +151.6% | 611,984 | $1.2M |
| Geode Capital Management, LLC | 0.00% | Add +1.3% | 560,909 | $1.1M |
| Goldman Sachs Group Inc. | 0.00% | Add +152.7% | 297,437 | $580K |
| Dimensional Fund Advisors LP | 0.00% | Reduce -21.7% | 285,439 | $556K |
| Renaissance Technologies | 0.00% | Reduce -74.2% | 259,900 | $507K |
| Alyeska Investment Group, L.P. | 0.00% | No change | 253,468 | $494K |
| Jane Street Group, LLC | 0.00% | Add +39.6% | 206,837 | $403K |
| State Street Corp. | 0.00% | Add +12.6% | 201,255 | $392K |
| Hillman Co. | 0.14% | No change | 200,000 | $390K |
| BlackRock, Inc. | 0.00% | Reduce -6.0% | 189,431 | $369K |
| Crewe Advisors LLC | 0.02% | No change | 136,052 | $265K |
| Bridgeway Capital Management, LLC | 0.01% | Add +4.0% | 130,000 | $254K |
| Gsa Capital Partners LLP | 0.02% | Reduce -52.1% | 124,051 | $242K |
| Qube Research & Technologies Ltd | 0.00% | Add +138.3% | 123,121 | $240K |
| Marshall Wace, LLP | 0.00% | New | 117,059 | $228K |
| Corient Private Wealth LP | 0.00% | Reduce -64.0% | 114,788 | $224K |
| Northern Trust Corp. | 0.00% | Reduce -9.2% | 107,011 | $209K |
| OMERS ADMINISTRATION Corp | 0.00% | New | 104,785 | $204K |
| Citigroup Inc. | 0.00% | Add +6881.0% | 61,712 | $120K |
| Point72 Asset Management | 0.00% | New | 60,833 | $119K |
| HSBC Holdings PLC | 0.00% | Reduce -0.3% | 49,449 | $98K |
| Barclays PLC | 0.00% | No change | 48,254 | $94K |
| Ashton Thomas Private Wealth, LLC | 0.00% | No change | 45,000 | $88K |
| Fayez Sarofim & Co | 0.00% | No change | 45,000 | $88K |
| Caprock Group, LLC | 0.00% | Add +158.0% | 44,090 | $86K |
| Susquehanna International Group, LLP | 0.00% | New | 42,916 | $84K |
| Palumbo Wealth Management LLC | 0.02% | Reduce -2.3% | 41,133 | $80K |
| Lighthouse Investment Partners, LLC | 0.00% | New | 40,200 | $78K |
| Morgan Stanley | 0.00% | Add +50.0% | 38,584 | $75K |
| Presidio Capital Management, LLC | 0.02% | No change | 34,664 | $68K |
| Captrust Financial Advisors | 0.00% | New | 34,011 | $66K |
| XTX Topco Ltd | 0.00% | Reduce -26.5% | 33,608 | $66K |
| Badgley Phelps Wealth Managers, LLC | 0.00% | No change | 30,000 | $59K |
| BNP Paribas Financial Markets | 0.00% | Add +1791.5% | 27,711 | $54K |
| Callan Family Office, LLC | 0.00% | Add +75.1% | 25,970 | $51K |
| Virtu Financial LLC | 0.00% | Add +19.6% | 23,532 | $46K |
| Bank of America Corp. | 0.00% | Add +2380.6% | 20,167 | $39K |
| Hudson Bay Capital Management LP | 0.00% | New | 19,062 | $37K |
| Garde Capital, Inc. | 0.00% | New | 18,000 | $35K |
| Two Sigma Securities, LLC | 0.00% | New | 16,239 | $32K |
| FNY Investment Advisers, LLC | 0.01% | No change | 14,000 | $27K |
| Vanguard Capital Wealth Advisors | 0.02% | Reduce -3.7% | 13,000 | $25K |
| Squarepoint Ops LLC | 0.00% | Reduce -91.4% | 11,316 | $22K |
| UBS Group AG | 0.00% | Add +998.5% | 5,163 | $10K |
| Rockefeller Capital Management L.P. | 0.00% | No change | 5,000 | $10K |
| Group One Trading LLC | 0.00% | New | 3,880 | $8K |
| FMR LLC | 0.00% | Reduce -59.8% | 3,486 | $7K |
| Royal Bank of Canada | 0.00% | Add +79.7% | 3,274 | $6K |
| TD Waterhouse Canada Inc. | 0.00% | No change | 1,000 | $2K |
| Osaic Holdings, Inc. | 0.00% | No change | 715 | $1K |
| Wells Fargo & Company | 0.00% | No change | 560 | $1K |
| Your Advocates Ltd., LLP | 0.00% | No change | 150 | $293 |
| EverSource Wealth Advisors, LLC | 0.00% | Reduce -78.6% | 49 | $96 |
| Optiver Holding B.V. | 0.00% | No change | 40 | $78 |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -99.9% | 5 | $10 |
| Cwm, LLC | 0.00% | Reduce -69.8% | 55 | $0 |
| Covestor Ltd | 0.00% | No change | 8 | $0 |
"% of holder's portfolio" is NAUT's weight in each manager's 13F, not the share of Nautilus Biotechnology Inc. the manager owns.