Opko HealthOPK
13F holders, Q1 2025 (March 31)255holders +20
41new positions
24sold out
7famous investors
$1.66avg. 13F price*
At the end of Q1 2025, 255 institutions reported holding Opko Health Inc. (OPK) in their 13F filings, up 20 from Q4 2024. 41 opened new positions and 24 sold out. The largest holders were Rubric Capital Management LP ($80.9M), Vanguard Group Inc. ($49.0M) and BlackRock, Inc. ($45.8M). 7 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).
- Company
- Opko Health Inc.
- CUSIP
- 68375N103
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 41 | $65.0M |
| Exits | 24 | $3.9M |
All 13F filers, Q4 2024 → Q1 2025: 58,753,025 shares bought and 14,241,445 shares sold, net +44,511,580 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 255 holders
| Rubric Capital Management LP | 1.45% | No change | 48,706,640 | $80.9M |
| Vanguard Group Inc. | 0.00% | Add +1.0% | 29,500,071 | $49.0M |
| BlackRock, Inc. | 0.00% | Reduce -2.0% | 27,604,974 | $45.8M |
| Sculptor Capital LP | 0.74% | New | 12,717,400 | $21.1M |
| Weiss Asset Management LP | 0.73% | New | 11,192,800 | $18.6M |
| Geode Capital Management, LLC | 0.00% | Add +0.5% | 8,428,840 | $14.0M |
| State Street Corp. | 0.00% | Reduce -10.3% | 8,139,496 | $13.5M |
| Deerfield Management Company, L.P. | 0.26% | New | 6,906,362 | $11.5M |
| Millennium Management | 0.01% | Add +39.2% | 6,386,911 | $10.6M |
| Marshall Wace, LLP | 0.01% | Add +431.4% | 4,896,428 | $8.1M |
| D. E. Shaw & Co. | 0.01% | New | 4,731,688 | $7.9M |
| Bank of America Corp. | 0.00% | Add +615.1% | 4,158,882 | $6.9M |
| Morgan Stanley | 0.00% | Add +29.7% | 4,108,488 | $6.8M |
| Goldman Sachs Group Inc. | 0.00% | Add +4.2% | 4,001,214 | $6.6M |
| Lazard Asset Management LLC | 0.01% | Add +41.6% | 3,609,314 | $6.0M |
| Northern Trust Corp. | 0.00% | Reduce -4.5% | 3,529,392 | $5.9M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -21.6% | 2,741,986 | $4.6M |
| JPMorgan Chase & Co. | 0.00% | Add +58.8% | 2,501,332 | $4.2M |
| UBS Group AG | 0.00% | Reduce -49.9% | 2,417,053 | $4.0M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -2.0% | 2,222,512 | $3.7M |
| Citadel Advisors | 0.00% | Reduce -42.2% | 1,856,526 | $3.1M |
| AWM Investment Company, Inc. | 0.42% | Add +42.3% | 1,850,000 | $3.1M |
| Graham Capital Management, L.P. | 0.14% | New | 1,810,392 | $3.0M |
| Y.D. More Investments Ltd | 0.26% | Add +27.0% | 1,772,947 | $3.0M |
| Two Sigma Investments, LP | 0.01% | Reduce -0.1% | 1,645,775 | $2.7M |
| Invesco Ltd. | 0.00% | Add +4.5% | 1,623,600 | $2.7M |
| AQR Capital Management | 0.00% | Add +466.7% | 1,608,906 | $2.7M |
| Altshuler Shaham Ltd | 0.06% | Add +3.1% | 1,454,221 | $2.4M |
| Nuveen, LLC | 0.00% | — | 1,376,881 | $2.3M |
| Gsa Capital Partners LLP | 0.20% | Add +24.2% | 1,343,701 | $2.2M |
| PFG Investments, LLC | 0.13% | Add +4.9% | 1,217,360 | $2.0M |
| Bank of New York Mellon Corp | 0.00% | Reduce -0.4% | 1,020,521 | $1.7M |
| Assenagon Asset Management S.A. | 0.00% | Add +9.2% | 935,100 | $1.6M |
| BNP Paribas Financial Markets | 0.00% | Add +1618.7% | 891,145 | $1.5M |
| Clearstead Advisors, LLC | 0.02% | No change | 883,042 | $1.5M |
| HRT Financial LP | 0.01% | Add +31.4% | 880,240 | $1.5M |
| Tejara Capital Ltd | 0.70% | Reduce -29.8% | 860,344 | $1.4M |
| Voya Investment Management LLC | 0.00% | Reduce -35.5% | 809,876 | $1.3M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +3.8% | 781,634 | $1.3M |
| Susquehanna International Group, LLP | 0.00% | Add +421.0% | 756,146 | $1.3M |
| Swiss National Bank | 0.00% | Reduce -3.5% | 661,155 | $1.1M |
| Osaic Holdings, Inc. | 0.00% | Add +22.6% | 651,809 | $1.1M |
| Two Sigma Advisers, LP | 0.00% | Add +44.7% | 551,697 | $916K |
| Jane Street Group, LLC | 0.00% | Reduce -80.4% | 549,338 | $912K |
| Alliancebernstein L.P. | 0.00% | Add +34.4% | 504,390 | $837K |
| T. Rowe Price Associates Inc. | 0.00% | Add +10.1% | 501,668 | $833K |
| Norges Bank | 0.00% | Reduce -56.2% | 494,257 | $820K |
| Rhumbline Advisers | 0.00% | Reduce -5.5% | 490,279 | $814K |
| Commonwealth Equity Services, LLC | 0.00% | Add +10.6% | 479,830 | $797K |
| X-Square Capital, LLC | 0.33% | Add +184.7% | 460,425 | $764K |
| Barclays PLC | 0.00% | Reduce -57.2% | 391,991 | $651K |
| SG Americas Securities, LLC | 0.00% | New | 352,276 | $585K |
| Legal & General Group Plc | 0.00% | Reduce -5.5% | 350,098 | $581K |
| Exchange Traded Concepts, LLC | 0.01% | Reduce -3.7% | 338,948 | $563K |
| California State Teachers Retirement System | 0.00% | No change | 324,117 | $538K |
| Verition Fund Management LLC | 0.00% | New | 317,946 | $528K |
| XTX Topco Ltd | 0.03% | Add +58.8% | 309,290 | $513K |
| Squarepoint Ops LLC | 0.00% | Add +123.0% | 301,861 | $501K |
| Deutsche Bank AG | 0.00% | Reduce -9.1% | 281,647 | $468K |
| Citigroup Inc. | 0.00% | Reduce -2.3% | 263,901 | $438K |
| Tudor Investment Corporation | 0.00% | No change | 244,821 | $406K |
| Royal Bank of Canada | 0.00% | Reduce -2.2% | 236,609 | $393K |
| Wells Fargo & Company | 0.00% | Add +0.3% | 230,015 | $382K |
| Engineers Gate Manager LP | 0.01% | Reduce -47.8% | 216,357 | $359K |
| Janus Henderson Group PLC | 0.00% | No change | 206,314 | $352K |
| Quantbot Technologies LP | 0.01% | New | 210,079 | $349K |
| ExodusPoint Capital Management, LP | 0.00% | Add +20.5% | 209,300 | $347K |
| Zazove Associates LLC | 0.63% | Add +4136.7% | 207,600 | $345K |
| Intech Investment Management LLC | 0.00% | Add +1.4% | 204,317 | $339K |
| Connor, Clark & Lunn Investment Management Ltd. | 0.00% | Add +802.9% | 201,345 | $334K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +1.3% | 189,194 | $314K |
| Ieq Capital, LLC | 0.00% | Add +417.7% | 183,363 | $304K |
| Capula Management Ltd | 0.00% | New | 182,512 | $303K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 176,260 | $293K |
| GAMCO Investors | 0.00% | No change | 175,000 | $291K |
| Gabelli Funds LLC | 0.00% | No change | 170,000 | $282K |
| MetLife Investment Management, LLC | 0.00% | Reduce -18.8% | 164,230 | $273K |
| Corebridge Financial, Inc. | 0.00% | Reduce -3.5% | 156,247 | $259K |
| Teton Advisors, Inc. | 0.16% | Reduce -3.7% | 144,500 | $240K |
| Numerai GP LLC | 0.04% | Reduce -4.7% | 133,187 | $221K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -4.6% | 124,731 | $207K |
| Cubist Systematic Strategies, LLC | 0.00% | Add +2369.9% | 119,223 | $198K |
| Highline Wealth Partners LLC | 0.07% | No change | 116,680 | $194K |
| Van Eck Associates Corp. | 0.00% | Add +6.3% | 113,506 | $188K |
| Comerica Bank | 0.00% | Add +5.3% | 112,000 | $186K |
| Phoenix Financial Ltd. | 0.00% | No change | 100,000 | $171K |
| Cambridge Investment Research Advisors, Inc. | 0.00% | No change | 103,110 | $171K |
| Csenge Advisory Group | 0.01% | No change | 117,000 | $166K |
| Intrepid Capital Management Inc. | 0.10% | No change | 100,000 | $166K |
| Arizona State Retirement System | 0.00% | Reduce -3.0% | 97,883 | $162K |
| Ameriprise Financial Inc. | 0.00% | Reduce -0.3% | 94,091 | $156K |
| American Century Companies Inc. | 0.00% | New | 92,785 | $154K |
| Hollencrest Capital Management | 0.01% | No change | 90,000 | $149K |
| Raymond James Financial Inc. | 0.00% | Reduce -43.3% | 85,370 | $142K |
| Balyasny Asset Management L.P. | 0.00% | Add +682.2% | 84,196 | $140K |
| Teacher Retirement System of Texas | 0.00% | New | 83,766 | $139K |
| 360 Financial, Inc. | 0.05% | Reduce -1.9% | 79,300 | $132K |
| Caxton Associates LLP | 0.00% | — | 78,128 | $130K |
| Quadrature Capital Ltd | 0.00% | New | 77,658 | $129K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 77,449 | $129K |
"% of holder's portfolio" is OPK's weight in each manager's 13F, not the share of Opko Health Inc. the manager owns.