Opko HealthOPK
13F holders, Q3 2025 (September 30)233holders +11
27new positions
14sold out
6famous investors
$1.55avg. 13F price*
At the end of Q3 2025, 233 institutions reported holding Opko Health Inc. (OPK) in their 13F filings, up 11 from Q2 2025. 27 opened new positions and 14 sold out. The largest holders were Rubric Capital Management LP ($74.1M), Vanguard Group Inc. ($58.2M) and BlackRock, Inc. ($51.4M). 6 famous investors held it, including Cliff Asness (0.0% of AQR Capital Management's portfolio), Mario Gabelli (0.0% of GAMCO Investors's portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).
- Company
- Opko Health Inc.
- CUSIP
- 68375N103
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 27 | $1.1M |
| Exits | 14 | $6.9M |
All 13F filers, Q2 2025 → Q3 2025: 11,185,977 shares bought and 20,016,961 shares sold, net −8,830,984 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 233 holders
| Rubric Capital Management LP | 1.00% | No change | 47,791,243 | $74.1M |
| Vanguard Group Inc. | 0.00% | Reduce -1.8% | 37,535,897 | $58.2M |
| BlackRock, Inc. | 0.00% | Add +5.5% | 33,172,384 | $51.4M |
| Geode Capital Management, LLC | 0.00% | Add +5.5% | 10,993,345 | $17.0M |
| State Street Corp. | 0.00% | Add +4.8% | 8,997,940 | $13.9M |
| Whitefort Capital Management, LP | 2.64% | Add +176.2% | 4,900,000 | $7.6M |
| UBS Group AG | 0.00% | Reduce -16.5% | 4,775,536 | $7.4M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +12.5% | 3,768,934 | $5.8M |
| Northern Trust Corp. | 0.00% | Add +5.0% | 3,657,846 | $5.7M |
| AQR Capital Management | 0.00% | Add +207.0% | 2,873,416 | $4.5M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -15.4% | 2,386,535 | $3.7M |
| AWM Investment Company, Inc. | 0.32% | Add +10.0% | 2,200,000 | $3.4M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -13.6% | 1,667,368 | $2.6M |
| Y.D. More Investments Ltd | 0.13% | Reduce -1.9% | 1,499,118 | $2.2M |
| Washington Growth Strategies LLC | 1.50% | No change | 1,356,124 | $2.1M |
| PFG Investments, LLC | 0.11% | Add +5.7% | 1,337,375 | $2.1M |
| Bank of America Corp. | 0.00% | Reduce -31.1% | 1,313,882 | $2.0M |
| Bank of New York Mellon Corp | 0.00% | Add +11.1% | 1,276,868 | $2.0M |
| Two Sigma Investments, LP | 0.00% | Reduce -31.6% | 1,255,647 | $1.9M |
| Voya Investment Management LLC | 0.00% | Reduce -7.7% | 1,218,002 | $1.9M |
| Weiss Asset Management LP | 0.03% | Reduce -76.2% | 1,130,771 | $1.8M |
| Invesco Ltd. | 0.00% | Reduce -25.8% | 1,017,561 | $1.6M |
| Tejara Capital Ltd | 0.75% | Reduce -7.2% | 877,941 | $1.4M |
| Swiss National Bank | 0.00% | Add +46.5% | 845,755 | $1.3M |
| Nuveen, LLC | 0.00% | Reduce -25.3% | 841,836 | $1.3M |
| Morgan Stanley | 0.00% | Reduce -59.3% | 837,601 | $1.3M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -40.3% | 673,565 | $1.0M |
| Assenagon Asset Management S.A. | 0.00% | Reduce -26.2% | 690,200 | $1.0M |
| Commonwealth Equity Services, LLC | 0.00% | Add +6.8% | 592,330 | $918K |
| Barclays PLC | 0.00% | Reduce -11.5% | 587,753 | $911K |
| Rhumbline Advisers | 0.00% | Add +4.9% | 555,382 | $861K |
| JPMorgan Chase & Co. | 0.00% | Reduce -16.3% | 527,411 | $817K |
| Alliancebernstein L.P. | 0.00% | Add +1.5% | 475,190 | $737K |
| California State Teachers Retirement System | 0.00% | Add +28.2% | 415,386 | $644K |
| Connor, Clark & Lunn Investment Management Ltd. | 0.00% | Add +0.3% | 392,761 | $609K |
| Legal & General Group Plc | 0.00% | Add +8.8% | 386,837 | $598K |
| Two Sigma Advisers, LP | 0.00% | Reduce -46.9% | 344,097 | $533K |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -21.5% | 343,286 | $533K |
| Wells Fargo & Company | 0.00% | Add +26.3% | 342,486 | $531K |
| Susquehanna International Group, LLP | 0.00% | Reduce -53.8% | 297,835 | $462K |
| Citadel Advisors | 0.00% | Add +28.7% | 279,875 | $434K |
| Ieq Capital, LLC | 0.00% | Add +154.2% | 277,594 | $430K |
| Deutsche Bank AG | 0.00% | Add +15.1% | 275,188 | $427K |
| Royal Bank of Canada | 0.00% | Add +2.0% | 272,866 | $423K |
| Jane Street Group, LLC | 0.00% | Reduce -81.0% | 262,838 | $407K |
| Tudor Investment Corporation | 0.00% | No change | 244,821 | $379K |
| Manufacturers Life Insurance Company, The | 0.00% | Add +70.7% | 236,722 | $367K |
| Zazove Associates LLC | 0.73% | No change | 207,600 | $322K |
| MetLife Investment Management, LLC | 0.00% | Reduce -5.1% | 207,175 | $321K |
| Janus Henderson Group PLC | 0.00% | No change | 206,314 | $319K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -3.5% | 191,186 | $296K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 176,260 | $273K |
| GAMCO Investors | 0.00% | No change | 175,000 | $271K |
| Gabelli Funds LLC | 0.00% | No change | 170,000 | $264K |
| Simplex Trading, LLC | 0.01% | New | 150,566 | $233K |
| SIH Partners, LLLP | 0.02% | Add +116.3% | 150,125 | $233K |
| Intech Investment Management LLC | 0.00% | Add +1.2% | 143,323 | $222K |
| Teton Advisors, LLC | 0.14% | — | 142,000 | $220K |
| State of Wyoming | 0.02% | Add +65.8% | 135,954 | $211K |
| New York State Common Retirement Fund | 0.00% | Add +115.3% | 130,901 | $203K |
| Arizona State Retirement System | 0.00% | Add +45.8% | 128,608 | $199K |
| Cwm, LLC | 0.00% | Add +452.3% | 124,774 | $193K |
| Two Sigma Securities, LLC | 0.03% | New | 121,094 | $188K |
| BNP Paribas Financial Markets | 0.00% | Reduce -79.7% | 118,309 | $183K |
| Csenge Advisory Group | 0.01% | Add +0.0% | 117,001 | $181K |
| Highline Wealth Partners LLC | 0.05% | Add +0.0% | 116,681 | $181K |
| Humankind Investments LLC | 0.04% | Add +4.9% | 114,644 | $178K |
| Glenmede Investment Management, LP | 0.00% | Add +0.6% | 113,413 | $176K |
| Comerica Bank | 0.00% | No change | 112,000 | $174K |
| Van Eck Associates Corp. | 0.00% | Reduce -6.1% | 111,826 | $173K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +32.2% | 102,397 | $159K |
| Phoenix Financial Ltd. | 0.00% | No change | 100,000 | $156K |
| RPg Family Wealth Advisory, LLC | 0.03% | New | 98,990 | $153K |
| Graham Capital Management, L.P. | 0.01% | Reduce -94.8% | 98,368 | $152K |
| Cambridge Investment Research Advisors, Inc. | 0.00% | Reduce -6.4% | 96,511 | $150K |
| Ameriprise Financial Inc. | 0.00% | Add +0.5% | 95,241 | $148K |
| 360 Financial, Inc. | 0.05% | Add +2.8% | 91,300 | $142K |
| Hollencrest Capital Management | 0.01% | No change | 90,000 | $140K |
| SG Americas Securities, LLC | 0.00% | Reduce -57.8% | 87,017 | $135K |
| Teacher Retirement System of Texas | 0.00% | Add +59.0% | 81,525 | $126K |
| Creative Planning | 0.00% | Add +229.9% | 80,796 | $125K |
| Osaic Holdings, Inc. | 0.00% | Reduce -8.2% | 86,775 | $124K |
| Verition Fund Management LLC | 0.00% | Add +57.0% | 79,534 | $123K |
| Mercer Global Advisors Inc. | 0.00% | Add +97.0% | 77,886 | $121K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Add +104.8% | 75,749 | $117K |
| KLP Kapitalforvaltning As | 0.00% | No change | 74,000 | $115K |
| Cubist Systematic Strategies, LLC | 0.00% | Reduce -46.0% | 72,127 | $112K |
| ProShare Advisors LLC | 0.00% | Reduce -5.1% | 70,369 | $109K |
| Mariner, LLC | 0.00% | Add +186.4% | 69,006 | $107K |
| Captrust Financial Advisors | 0.00% | Add +62.3% | 68,026 | $105K |
| Cascade Financial Partners, LLC | 0.01% | No change | 66,490 | $103K |
| Pictet Asset Management Holding SA | 0.00% | No change | 65,495 | $102K |
| Arax Advisory Partners | 0.00% | New | 63,780 | $99K |
| Raymond James Financial Inc. | 0.00% | Reduce -6.0% | 62,205 | $96K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 61,502 | $95K |
| Renaissance Technologies | 0.00% | Add +56.7% | 59,700 | $93K |
| Brighton Jones LLC | 0.00% | Add +52.7% | 59,426 | $92K |
| Cetera Investment Advisers | 0.00% | Reduce -2.5% | 59,051 | $92K |
| Kestra Private Wealth Services, LLC | 0.00% | No change | 58,450 | $91K |
| PNC Financial Services Group, Inc. | 0.00% | Add +0.4% | 57,050 | $88K |
"% of holder's portfolio" is OPK's weight in each manager's 13F, not the share of Opko Health Inc. the manager owns.