Opko HealthOPK
13F holders, Q1 2026 (March 31)236holders +15
35new positions
22sold out
6famous investors
$1.14avg. 13F price*
At the end of Q1 2026, 236 institutions reported holding Opko Health Inc. (OPK) in their 13F filings, up 15 from Q4 2025. 35 opened new positions and 22 sold out. The largest holders were Rubric Capital Management LP ($54.5M), BlackRock, Inc. ($41.3M) and Vanguard Portfolio Management LLC ($16.8M). 6 famous investors held it, including Mario Gabelli (0.0% of GAMCO Investors's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).
- Company
- Opko Health Inc.
- CUSIP
- 68375N103
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 35 | $3.7M |
| Exits | 22 | $1.8M |
All 13F filers, Q4 2025 → Q1 2026: 10,012,437 shares bought and 8,341,568 shares sold, net +1,670,869 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 236 holders
| Rubric Capital Management LP | 0.67% | No change | 47,791,243 | $54.5M |
| BlackRock, Inc. | 0.00% | Add +4.0% | 36,232,223 | $41.3M |
| Vanguard Portfolio Management LLC | 0.00% | — | 14,769,719 | $16.8M |
| Vanguard Capital Management LLC | 0.00% | — | 14,499,164 | $16.5M |
| Geode Capital Management, LLC | 0.00% | Add +2.2% | 11,301,501 | $12.9M |
| State Street Corp. | 0.00% | Add +6.1% | 9,501,377 | $10.8M |
| Goldman Sachs Group Inc. | 0.00% | Add +28.2% | 7,675,026 | $8.7M |
| UBS Group AG | 0.00% | Add +13.4% | 6,071,432 | $6.9M |
| Whitefort Capital Management, LP | 1.53% | No change | 4,253,340 | $4.8M |
| Northern Trust Corp. | 0.00% | Add +5.3% | 3,619,346 | $4.1M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -3.2% | 3,574,039 | $4.1M |
| Vanguard Fiduciary Trust Co. | 0.00% | — | 2,742,017 | $3.1M |
| AWM Investment Company, Inc. | 0.27% | No change | 2,100,000 | $2.4M |
| Citadel Advisors | 0.00% | Reduce -27.2% | 2,079,547 | $2.4M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -3.2% | 1,560,000 | $1.8M |
| Washington Growth Strategies LLC | 1.01% | No change | 1,356,124 | $1.5M |
| Y.D. More Investments Ltd | 0.06% | Reduce -0.5% | 1,299,473 | $1.5M |
| Bank of New York Mellon Corp | 0.00% | Reduce -2.3% | 1,280,042 | $1.5M |
| Morgan Stanley | 0.00% | Add +30.4% | 1,196,087 | $1.4M |
| Voya Investment Management LLC | 0.00% | Add +5.3% | 1,160,927 | $1.3M |
| Bank of America Corp. | 0.00% | Add +84.7% | 1,141,849 | $1.3M |
| Jane Street Group, LLC | 0.00% | Reduce -37.2% | 1,114,375 | $1.3M |
| PFG Investments, LLC | 0.06% | Reduce -15.7% | 1,112,776 | $1.3M |
| OP Asset Management Ltd | 0.01% | New | 1,102,254 | $1.3M |
| Clearstead Advisors, LLC | 0.01% | Add +0.2% | 884,119 | $1.0M |
| Tejara Capital Ltd | 0.33% | No change | 877,941 | $1.0M |
| Nuveen, LLC | 0.00% | Add +0.6% | 846,993 | $966K |
| Swiss National Bank | 0.00% | No change | 845,755 | $964K |
| Invesco Ltd. | 0.00% | Add +1.5% | 793,169 | $904K |
| AQR Capital Management | 0.00% | Reduce -62.3% | 763,590 | $870K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +0.2% | 674,848 | $769K |
| Gsa Capital Partners LLP | 0.05% | Add +6.8% | 663,704 | $757K |
| Assenagon Asset Management S.A. | 0.00% | No change | 652,066 | $740K |
| Connor, Clark & Lunn Investment Management Ltd. | 0.00% | Add +21.4% | 522,906 | $596K |
| First Trust Advisors LP | 0.00% | New | 500,273 | $570K |
| Rhumbline Advisers | 0.00% | Reduce -2.8% | 497,240 | $567K |
| JPMorgan Chase & Co. | 0.00% | Reduce -12.3% | 508,484 | $559K |
| Alliancebernstein L.P. | 0.00% | Reduce -5.6% | 423,190 | $533K |
| Kovack Advisors, Inc. | 0.03% | New | 459,700 | $524K |
| XTX Topco Ltd | 0.01% | Add +25.7% | 430,966 | $491K |
| Commonwealth Equity Services, LLC | 0.00% | Reduce -32.8% | 430,906 | $491K |
| California State Teachers Retirement System | 0.00% | Reduce -0.7% | 414,037 | $472K |
| T. Rowe Price Associates Inc. | 0.00% | Add +10.2% | 404,652 | $462K |
| Qube Research & Technologies Ltd | 0.00% | Add +293.5% | 404,358 | $461K |
| Susquehanna International Group, LLP | 0.00% | Reduce -10.5% | 391,516 | $446K |
| Deutsche Bank AG | 0.00% | Add +13.8% | 370,948 | $423K |
| Legal & General Group Plc | 0.00% | Reduce -24.2% | 343,474 | $392K |
| EntryPoint Capital, LLC | 0.11% | Add +10.7% | 342,171 | $390K |
| VANGUARD ASSET MANAGEMENT, Ltd | 0.00% | — | 294,013 | $335K |
| Tudor Investment Corporation | 0.00% | No change | 244,821 | $279K |
| HSBC Holdings PLC | 0.00% | New | 238,281 | $273K |
| Royal Bank of Canada | 0.00% | Reduce -15.7% | 219,994 | $251K |
| Janus Henderson Group PLC | 0.00% | No change | 206,314 | $236K |
| MetLife Investment Management, LLC | 0.00% | Add +16.5% | 204,738 | $233K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +3.6% | 197,906 | $226K |
| Vanguard Global Advisers, LLC | 0.00% | — | 181,766 | $207K |
| Creative Planning | 0.00% | Add +204.8% | 176,985 | $202K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 176,260 | $201K |
| GAMCO Investors | 0.00% | No change | 175,000 | $200K |
| Gabelli Funds LLC | 0.00% | No change | 170,000 | $194K |
| Two Sigma Investments, LP | 0.00% | Reduce -76.9% | 170,000 | $194K |
| State of Wyoming | 0.02% | New | 167,020 | $190K |
| Wells Fargo & Company | 0.00% | Reduce -65.3% | 162,609 | $185K |
| Van Eck Associates Corp. | 0.00% | Add +16.8% | 160,096 | $183K |
| Zazove Associates LLC | 0.31% | No change | 150,000 | $171K |
| ProShare Advisors LLC | 0.00% | Reduce -10.0% | 140,658 | $160K |
| Teton Advisors, LLC | 0.11% | No change | 140,000 | $160K |
| Barclays PLC | 0.00% | Reduce -79.2% | 138,300 | $158K |
| U.S. Capital Wealth Advisors, LLC | 0.00% | New | 133,261 | $152K |
| Fifth Third Bancorp | 0.00% | New | 128,791 | $147K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +1310.1% | 128,713 | $147K |
| Intech Investment Management LLC | 0.00% | Reduce -21.2% | 125,814 | $143K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -46.8% | 122,128 | $139K |
| Highline Wealth Partners LLC | 0.03% | Reduce 0.0% | 116,680 | $133K |
| Arizona State Retirement System | 0.00% | Add +1.9% | 115,978 | $132K |
| New York State Common Retirement Fund | 0.00% | No change | 114,301 | $130K |
| Glenmede Trust Co. NA | 0.00% | Reduce -0.7% | 112,750 | $129K |
| Vanguard Investments Australia, Ltd. | 0.00% | — | 110,958 | $126K |
| Renaissance Technologies | 0.00% | New | 109,543 | $125K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 102,397 | $117K |
| 360 Financial, Inc. | 0.03% | Add +11.4% | 97,300 | $111K |
| Ameriprise Financial Inc. | 0.00% | Add +0.5% | 96,722 | $110K |
| Point72 Asset Management | 0.00% | New | 93,335 | $106K |
| Ieq Capital, LLC | 0.00% | Reduce -40.9% | 93,222 | $106K |
| KLP Kapitalforvaltning As | 0.00% | No change | 90,700 | $103K |
| Cambridge Investment Research Advisors, Inc. | 0.00% | Add +0.6% | 90,279 | $103K |
| HRT Financial LP | 0.00% | Reduce -86.6% | 90,759 | $103K |
| BNP Paribas Financial Markets | 0.00% | Reduce -0.8% | 89,732 | $102K |
| Quadrature Capital Ltd | 0.00% | Reduce -3.0% | 88,937 | $101K |
| RPg Family Wealth Advisory, LLC | 0.02% | Reduce -10.5% | 88,619 | $101K |
| SG Americas Securities, LLC | 0.00% | Add +62.6% | 87,846 | $100K |
| Cwm, LLC | 0.00% | Add +1.0% | 69,834 | $80K |
| World Investment Advisors | 0.00% | No change | 66,520 | $76K |
| Cascade Financial Partners, LLC | 0.01% | No change | 66,490 | $76K |
| Prudential Financial Inc. | 0.00% | Add +148.6% | 65,556 | $75K |
| Pictet Asset Management Holding SA | 0.00% | No change | 65,495 | $75K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Add +8.4% | 62,365 | $71K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 61,502 | $70K |
| Cetera Investment Advisers | 0.00% | Add +0.3% | 59,352 | $68K |
| Kestra Private Wealth Services, LLC | 0.00% | No change | 58,450 | $67K |
"% of holder's portfolio" is OPK's weight in each manager's 13F, not the share of Opko Health Inc. the manager owns.