Opko HealthOPK
13F holders, Q1 2025 (March 31)At the end of Q1 2025, 255 institutions reported holding Opko Health Inc. (OPK) in their 13F filings, up 20 from Q4 2024. 41 opened new positions and 24 sold out. The largest holders were Rubric Capital Management LP ($80.9M), Vanguard Group Inc. ($49.0M) and BlackRock, Inc. ($45.8M). 7 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).
- Company
- Opko Health Inc.
- CUSIP
- 68375N103
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 41 | $65.0M |
| Exits | 24 | $3.9M |
All 13F filers, Q4 2024 → Q1 2025: 58,753,025 shares bought and 14,241,445 shares sold, net +44,511,580 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 255 holders
| Rubric Capital Management LP | 1.45% | No change | 48,706,640 | $80.9M |
| Vanguard Group Inc. | 0.00% | Add +1.0% | 29,500,071 | $49.0M |
| BlackRock, Inc. | 0.00% | Reduce -2.0% | 27,604,974 | $45.8M |
| Sculptor Capital LP | 0.74% | New | 12,717,400 | $21.1M |
| Weiss Asset Management LP | 0.73% | New | 11,192,800 | $18.6M |
| Geode Capital Management, LLC | 0.00% | Add +0.5% | 8,428,840 | $14.0M |
| State Street Corp. | 0.00% | Reduce -10.3% | 8,139,496 | $13.5M |
| Deerfield Management Company, L.P. | 0.26% | New | 6,906,362 | $11.5M |
| Millennium Management | 0.01% | Add +39.2% | 6,386,911 | $10.6M |
| Marshall Wace, LLP | 0.01% | Add +431.4% | 4,896,428 | $8.1M |
| D. E. Shaw & Co. | 0.01% | New | 4,731,688 | $7.9M |
| Bank of America Corp. | 0.00% | Add +615.1% | 4,158,882 | $6.9M |
| Morgan Stanley | 0.00% | Add +29.7% | 4,108,488 | $6.8M |
| Goldman Sachs Group Inc. | 0.00% | Add +4.2% | 4,001,214 | $6.6M |
| Lazard Asset Management LLC | 0.01% | Add +41.6% | 3,609,314 | $6.0M |
| Northern Trust Corp. | 0.00% | Reduce -4.5% | 3,529,392 | $5.9M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -21.6% | 2,741,986 | $4.6M |
| JPMorgan Chase & Co. | 0.00% | Add +58.8% | 2,501,332 | $4.2M |
| UBS Group AG | 0.00% | Reduce -49.9% | 2,417,053 | $4.0M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -2.0% | 2,222,512 | $3.7M |
| Citadel Advisors | 0.00% | Reduce -42.2% | 1,856,526 | $3.1M |
| AWM Investment Company, Inc. | 0.42% | Add +42.3% | 1,850,000 | $3.1M |
| Graham Capital Management, L.P. | 0.14% | New | 1,810,392 | $3.0M |
| Y.D. More Investments Ltd | 0.26% | Add +27.0% | 1,772,947 | $3.0M |
| Two Sigma Investments, LP | 0.01% | Reduce -0.1% | 1,645,775 | $2.7M |
| Invesco Ltd. | 0.00% | Add +4.5% | 1,623,600 | $2.7M |
| AQR Capital Management | 0.00% | Add +466.7% | 1,608,906 | $2.7M |
| Altshuler Shaham Ltd | 0.06% | Add +3.1% | 1,454,221 | $2.4M |
| Nuveen, LLC | 0.00% | — | 1,376,881 | $2.3M |
| Gsa Capital Partners LLP | 0.20% | Add +24.2% | 1,343,701 | $2.2M |
| PFG Investments, LLC | 0.13% | Add +4.9% | 1,217,360 | $2.0M |
| Bank of New York Mellon Corp | 0.00% | Reduce -0.4% | 1,020,521 | $1.7M |
| Assenagon Asset Management S.A. | 0.00% | Add +9.2% | 935,100 | $1.6M |
| BNP Paribas Financial Markets | 0.00% | Add +1618.7% | 891,145 | $1.5M |
| Clearstead Advisors, LLC | 0.02% | No change | 883,042 | $1.5M |
| HRT Financial LP | 0.01% | Add +31.4% | 880,240 | $1.5M |
| Tejara Capital Ltd | 0.70% | Reduce -29.8% | 860,344 | $1.4M |
| Voya Investment Management LLC | 0.00% | Reduce -35.5% | 809,876 | $1.3M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +3.8% | 781,634 | $1.3M |
| Susquehanna International Group, LLP | 0.00% | Add +421.0% | 756,146 | $1.3M |
| Swiss National Bank | 0.00% | Reduce -3.5% | 661,155 | $1.1M |
| Osaic Holdings, Inc. | 0.00% | Add +22.6% | 651,809 | $1.1M |
| Two Sigma Advisers, LP | 0.00% | Add +44.7% | 551,697 | $916K |
| Jane Street Group, LLC | 0.00% | Reduce -80.4% | 549,338 | $912K |
| Alliancebernstein L.P. | 0.00% | Add +34.4% | 504,390 | $837K |
| T. Rowe Price Associates Inc. | 0.00% | Add +10.1% | 501,668 | $833K |
| Norges Bank | 0.00% | Reduce -56.2% | 494,257 | $820K |
| Rhumbline Advisers | 0.00% | Reduce -5.5% | 490,279 | $814K |
| Commonwealth Equity Services, LLC | 0.00% | Add +10.6% | 479,830 | $797K |
| X-Square Capital, LLC | 0.33% | Add +184.7% | 460,425 | $764K |
| Barclays PLC | 0.00% | Reduce -57.2% | 391,991 | $651K |
| SG Americas Securities, LLC | 0.00% | New | 352,276 | $585K |
| Legal & General Group Plc | 0.00% | Reduce -5.5% | 350,098 | $581K |
| Exchange Traded Concepts, LLC | 0.01% | Reduce -3.7% | 338,948 | $563K |
| California State Teachers Retirement System | 0.00% | No change | 324,117 | $538K |
| Verition Fund Management LLC | 0.00% | New | 317,946 | $528K |
| XTX Topco Ltd | 0.03% | Add +58.8% | 309,290 | $513K |
| Squarepoint Ops LLC | 0.00% | Add +123.0% | 301,861 | $501K |
| Deutsche Bank AG | 0.00% | Reduce -9.1% | 281,647 | $468K |
| Citigroup Inc. | 0.00% | Reduce -2.3% | 263,901 | $438K |
| Tudor Investment Corporation | 0.00% | No change | 244,821 | $406K |
| Royal Bank of Canada | 0.00% | Reduce -2.2% | 236,609 | $393K |
| Wells Fargo & Company | 0.00% | Add +0.3% | 230,015 | $382K |
| Engineers Gate Manager LP | 0.01% | Reduce -47.8% | 216,357 | $359K |
| Janus Henderson Group PLC | 0.00% | No change | 206,314 | $352K |
| Quantbot Technologies LP | 0.01% | New | 210,079 | $349K |
| ExodusPoint Capital Management, LP | 0.00% | Add +20.5% | 209,300 | $347K |
| Zazove Associates LLC | 0.63% | Add +4136.7% | 207,600 | $345K |
| Intech Investment Management LLC | 0.00% | Add +1.4% | 204,317 | $339K |
| Connor, Clark & Lunn Investment Management Ltd. | 0.00% | Add +802.9% | 201,345 | $334K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +1.3% | 189,194 | $314K |
| Ieq Capital, LLC | 0.00% | Add +417.7% | 183,363 | $304K |
| Capula Management Ltd | 0.00% | New | 182,512 | $303K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 176,260 | $293K |
| GAMCO Investors | 0.00% | No change | 175,000 | $291K |
| Gabelli Funds LLC | 0.00% | No change | 170,000 | $282K |
| MetLife Investment Management, LLC | 0.00% | Reduce -18.8% | 164,230 | $273K |
| Corebridge Financial, Inc. | 0.00% | Reduce -3.5% | 156,247 | $259K |
| Teton Advisors, Inc. | 0.16% | Reduce -3.7% | 144,500 | $240K |
| Numerai GP LLC | 0.04% | Reduce -4.7% | 133,187 | $221K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -4.6% | 124,731 | $207K |
| Cubist Systematic Strategies, LLC | 0.00% | Add +2369.9% | 119,223 | $198K |
| Highline Wealth Partners LLC | 0.07% | No change | 116,680 | $194K |
| Van Eck Associates Corp. | 0.00% | Add +6.3% | 113,506 | $188K |
| Comerica Bank | 0.00% | Add +5.3% | 112,000 | $186K |
| Phoenix Financial Ltd. | 0.00% | No change | 100,000 | $171K |
| Cambridge Investment Research Advisors, Inc. | 0.00% | No change | 103,110 | $171K |
| Csenge Advisory Group | 0.01% | No change | 117,000 | $166K |
| Intrepid Capital Management Inc. | 0.10% | No change | 100,000 | $166K |
| Arizona State Retirement System | 0.00% | Reduce -3.0% | 97,883 | $162K |
| Ameriprise Financial Inc. | 0.00% | Reduce -0.3% | 94,091 | $156K |
| American Century Companies Inc. | 0.00% | New | 92,785 | $154K |
| Hollencrest Capital Management | 0.01% | No change | 90,000 | $149K |
| Raymond James Financial Inc. | 0.00% | Reduce -43.3% | 85,370 | $142K |
| Balyasny Asset Management L.P. | 0.00% | Add +682.2% | 84,196 | $140K |
| Teacher Retirement System of Texas | 0.00% | New | 83,766 | $139K |
| 360 Financial, Inc. | 0.05% | Reduce -1.9% | 79,300 | $132K |
| Caxton Associates LLP | 0.00% | — | 78,128 | $130K |
| Quadrature Capital Ltd | 0.00% | New | 77,658 | $129K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 77,449 | $129K |
| Two Sigma Securities, LLC | 0.02% | Reduce -0.2% | 75,647 | $126K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Add +158.4% | 74,706 | $124K |
| Cwm, LLC | 0.00% | Add +961.9% | 74,503 | $124K |
| KLP Kapitalforvaltning As | 0.00% | No change | 74,000 | $123K |
| Cibc World Markets Corp. | 0.00% | Add +132.2% | 70,769 | $117K |
| ProShare Advisors LLC | 0.00% | Reduce -24.7% | 69,045 | $115K |
| Cascade Financial Partners, LLC | 0.01% | No change | 66,490 | $110K |
| Pictet Asset Management Holding SA | 0.00% | No change | 65,495 | $109K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 61,502 | $102K |
| New York State Common Retirement Fund | 0.00% | No change | 60,801 | $101K |
| Cetera Investment Advisers | 0.00% | No change | 60,556 | $101K |
| Kestra Private Wealth Services, LLC | 0.00% | Reduce -2.1% | 58,450 | $97K |
| PNC Financial Services Group, Inc. | 0.00% | No change | 56,800 | $94K |
| Private Advisor Group, LLC | 0.00% | Add +56.7% | 55,301 | $92K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | No change | 55,140 | $92K |
| Mercer Global Advisors Inc. | 0.00% | Add +27.3% | 54,957 | $91K |
| CANADA LIFE ASSURANCE Co | 0.00% | No change | 54,068 | $90K |
| Headlands Technologies LLC | 0.01% | New | 52,149 | $87K |
| First Manhattan Co. Llc. | 0.00% | No change | 51,750 | $86K |
| Transcend Capital Advisors, LLC | 0.01% | No change | 50,850 | $84K |
| Group One Trading LLC | 0.00% | Reduce -92.2% | 50,794 | $84K |
| Kestra Advisory Services, LLC | 0.00% | No change | 50,307 | $84K |
| Farmers National Bank | 0.02% | No change | 50,300 | $83K |
| Jump Financial, LLC | 0.00% | New | 49,070 | $81K |
| Captrust Financial Advisors | 0.00% | Add +29.2% | 48,482 | $80K |
| Inspire Advisors, LLC | 0.01% | New | 47,130 | $78K |
| Humankind Investments LLC | 0.02% | Reduce -2.5% | 46,413 | $77K |
| Aquatic Capital Management LLC | 0.00% | New | 45,966 | $76K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +138.2% | 42,450 | $70K |
| Shell Asset Management Co. | 0.00% | Add +1.5% | 40,997 | $68K |
| Atom Investors LP | 0.01% | Add +24.4% | 40,760 | $68K |
| World Investment Advisors | 0.00% | No change | 40,618 | $67K |
| RK Asset Management, LLC | 0.06% | Add +11.0% | 40,485 | $67K |
| HighTower Advisors, LLC | 0.00% | Reduce -2.7% | 38,906 | $65K |
| HSBC Holdings PLC | 0.00% | Reduce -2.7% | 36,852 | $61K |
| Victory Capital Management Inc. | 0.00% | Reduce -4.5% | 36,616 | $61K |
| Choreo, LLC | 0.00% | Reduce -9.0% | 33,757 | $56K |
| Operose Advisors LLC | 0.02% | No change | 32,000 | $53K |
| Norris Perne & French LLP | 0.00% | Add +6.7% | 32,000 | $53K |
| STRS Ohio | 0.00% | No change | 31,900 | $53K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 31,889 | $53K |
| Brighton Jones LLC | 0.00% | Add +0.5% | 30,141 | $50K |
| IPG Investment Advisors LLC | 0.01% | No change | 30,000 | $50K |
| Orion Porfolio Solutions, LLC | 0.00% | No change | 30,000 | $50K |
| Orion Portfolio Solutions, LLC | 0.00% | No change | 30,000 | $50K |
| Cibc World Market Inc. | 0.00% | No change | 29,928 | $50K |
| State of Wisconsin Investment Board | 0.00% | Reduce -12.1% | 29,770 | $49K |
| Capital Advisors Inc. | 0.00% | Add +133.3% | 350,000 | $49K |
| EP Wealth Advisors, LLC | 0.00% | Add +1.2% | 29,238 | $49K |
| Equitable Holdings, Inc. | 0.00% | Add +0.0% | 28,931 | $48K |
| Point72 (DIFC) Ltd | 0.00% | Add +27.1% | 28,907 | $48K |
| Creative Planning | 0.00% | Add +15.8% | 28,097 | $47K |
| Voleon Capital Management LP | 0.00% | New | 27,225 | $45K |
| PBMares Wealth Management LLC | 0.01% | No change | 27,021 | $45K |
| Prudential Financial Inc. | 0.00% | Reduce -14.6% | 26,766 | $44K |
| Cim Investment Management Inc. | 0.01% | Reduce -2.3% | 26,697 | $44K |
| SlateStone Wealth, LLC | 0.00% | No change | 25,770 | $43K |
| Pallas Capital Advisors LLC | 0.00% | New | 25,851 | $43K |
| Mackenzie Financial Corp. | 0.00% | No change | 25,843 | $43K |
| Diversify Wealth Management, LLC | 0.00% | No change | 30,000 | $42K |
| FMR LLC | 0.00% | Add +0.4% | 24,388 | $40K |
| Jain Global LLC | 0.00% | New | 24,200 | $40K |
| Moseley Investment Management Inc. | 0.02% | No change | 24,153 | $40K |
| Xponance LLC | 0.00% | Add +2.1% | 23,758 | $39K |
| Tidal Investments LLC | 0.00% | New | 23,618 | $39K |
| CIBC Asset Management Inc | 0.00% | No change | 21,918 | $36K |
| Cerity Partners LLC | 0.00% | New | 21,528 | $36K |
| Principal Financial Group Inc. | 0.00% | Add +17.1% | 21,125 | $35K |
| LPL Financial LLC | 0.00% | Reduce -38.6% | 20,333 | $34K |
| Aster Capital Management (DIFC) Ltd | 0.01% | Add +157.0% | 19,262 | $34K |
| Sax Wealth Advisors, LLC | 0.00% | No change | 20,110 | $33K |
| Sovereign Financial Group, Inc. | 0.01% | Add +0.1% | 20,084 | $33K |
| N.E.W. Advisory Services LLC | 0.00% | No change | 20,075 | $33K |
| GM Advisory Group, LLC | 0.00% | New | 20,000 | $33K |
| Cumberland Advisors Inc. | 0.01% | No change | 19,500 | $32K |
| Sigma Planning Corp | 0.00% | No change | 17,972 | $30K |
| Mariner, LLC | 0.00% | New | 17,463 | $29K |
| Shufro Rose & Co. LLC | 0.00% | No change | 17,000 | $28K |
| Stifel Financial Corp. | 0.00% | Add +0.4% | 16,849 | $28K |
| Caprock Group, LLC | 0.00% | New | 16,770 | $28K |
| Westmount Partners, LLC | 0.01% | No change | 16,550 | $27K |
| C2C Wealth Management, LLC | 0.03% | Add +9.3% | 16,405 | $27K |
| Commons Capital, LLC | 0.02% | No change | 16,300 | $27K |
| Oak Thistle LLC | 0.01% | New | 15,636 | $26K |
| Formidable Asset Management, LLC | 0.00% | No change | 15,046 | $25K |
| Colony Family Offices, LLC | 0.01% | No change | 14,729 | $24K |
| Sanctuary Advisors, LLC | 0.00% | New | 14,191 | $24K |
| Abel Hall, LLC | 0.01% | Add +39.9% | 14,170 | $24K |
| Blueshift Asset Management, LLC | 0.01% | New | 13,870 | $23K |
| Schonfeld Strategic Advisors LLC | 0.00% | New | 13,100 | $22K |
| Canada Pension Plan Investment Board | 0.00% | New | 12,900 | $21K |
| R Squared Ltd | 0.02% | New | 12,290 | $20K |
| Farther Finance Advisors, LLC | 0.00% | Add +3.1% | 12,219 | $20K |
| Jones Financial Companies LLLP | 0.00% | Add +34.8% | 11,625 | $20K |
| Farringdon Capital, Ltd. | 0.01% | New | 11,834 | $20K |
| Traphagen Investment Advisors LLC | 0.00% | No change | 11,680 | $19K |
| Focus Partners Wealth | 0.00% | New | 11,524 | $19K |
| HBK Sorce Advisory LLC | 0.00% | No change | 11,409 | $19K |
| Stillwater Capital Advisors, LLC | 0.00% | No change | 11,380 | $19K |
| Gotham Asset Management | 0.00% | New | 11,056 | $18K |
| Capital Square, LLC | 0.01% | Reduce -25.7% | 11,000 | $18K |
| Key Financial Inc | 0.00% | No change | 11,000 | $18K |
| Boothbay Fund Management, LLC | 0.00% | New | 10,930 | $18K |
| Diversified Trust Co. | 0.00% | Add +9.1% | 10,914 | $18K |
| Amalgamated Bank | 0.00% | No change | 11,110 | $18K |
| Merit Financial Group, LLC | 0.00% | New | 10,249 | $17K |
| Steward Partners Investment Advisory, LLC | 0.00% | Reduce -0.6% | 10,234 | $17K |
| Sei Investments Co. | 0.00% | No change | 10,163 | $17K |
| MRP Capital Investments, LLC | 0.02% | No change | 10,000 | $17K |
| Greenbush Financial Group, LLC | 0.01% | No change | 10,000 | $17K |
| KLCM Advisors, Inc. | 0.00% | No change | 10,000 | $17K |
| Kovack Advisors, Inc. | 0.00% | Reduce -0.0% | 10,000 | $17K |
| Atria Wealth Solutions, Inc. | 0.00% | Reduce -55.4% | 10,000 | $17K |
| Aventura Private Wealth, LLC | 0.01% | No change | 8,400 | $14K |
| Point72 Asia (Singapore) Pte. Ltd. | 0.00% | Reduce -83.4% | 6,914 | $11K |
| Raiffeisen Bank International AG | 0.00% | No change | 6,521 | $11K |
| Penserra Capital Management LLC | 0.00% | Add +5.5% | 6,434 | $10K |
| National Bank of Canada | 0.00% | Reduce -9.7% | 5,597 | $9K |
| Sterling Capital Management LLC | 0.00% | Reduce -47.3% | 5,503 | $9K |
| Quarry LP | 0.00% | Add +174.9% | 4,706 | $8K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -5.9% | 4,463 | $7K |
| FSA Wealth Management LLC | 0.00% | No change | 3,950 | $7K |
| Gables Capital Management Inc. | 0.00% | No change | 3,000 | $5K |
| Moser Wealth Advisors, LLC | 0.00% | No change | 2,392 | $4K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +99.0% | 2,280 | $4K |
| Caitong International Asset Management Co., Ltd | 0.00% | Add +75.7% | 1,820 | $3K |
| CoreCap Advisors, LLC | 0.00% | Add +8.4% | 1,734 | $3K |
| US Bancorp \de | 0.00% | Add +138.0% | 1,428 | $2K |
| Allworth Financial LP | 0.00% | No change | 1,623 | $2K |
| Washington Growth Strategies LLC | 2.02% | — | 2 | $2K |
| PFS Partners, LLC | 0.00% | No change | 1,100 | $2K |
| MAI Capital Management | 0.00% | No change | 1,000 | $2K |
| Salomon & Ludwin, LLC | 0.00% | No change | 995 | $2K |
| Transce3nd, LLC | 0.00% | Reduce -38.2% | 900 | $1K |
| True Wealth Design, LLC | 0.00% | Add +9650.0% | 780 | $1K |
| CBIZ Investment Advisory Services, LLC | 0.00% | No change | 698 | $1K |
| Russell Investments Group, Ltd. | 0.00% | Reduce -26.2% | 620 | $1K |
| Smartleaf Asset Management LLC | 0.00% | Reduce -87.5% | 474 | $805 |
| Grove Bank & Trust | 0.00% | New | 250 | $415 |
| Pittenger & Anderson Inc. | 0.00% | No change | 250 | $415 |
| Northwestern Mutual Wealth Management Co. | 0.00% | Reduce -50.0% | 227 | $377 |
| Medallion Wealth Advisors, LLC | 0.00% | New | 200 | $332 |
| Rothschild Investment LLC | 0.00% | No change | 200 | $332 |
| Harbor Investment Advisory, LLC | 0.00% | New | 180 | $299 |
| IFP Advisors, Inc | 0.00% | No change | 103 | $171 |
| Salem Investment Counselors Inc. | 0.00% | No change | 100 | $166 |
| Truvestments Capital LLC | 0.00% | New | 100 | $166 |
| SBI Securities Co., Ltd. | 0.00% | Add +2.2% | 93 | $154 |
| Larson Financial Group LLC | 0.00% | No change | 40 | $66 |
| NewEdge Advisors, LLC | 0.00% | No change | 19 | $32 |
| Darwin Wealth Management, LLC | 0.00% | No change | 5 | $7 |
| LRI Investments, LLC | 0.00% | New | 1 | $2 |
| Bessemer Group Inc. | 0.00% | New | 273 | $0 |
| Centerpoint Advisors, LLC | 0.00% | No change | 100 | $0 |
| Covestor Ltd | 0.00% | Reduce -17.1% | 87 | $0 |
"% of holder's portfolio" is OPK's weight in each manager's 13F, not the share of Opko Health Inc. the manager owns.