Puma BiotechnologyPBYI
13F holders, Q1 2025 (March 31)At the end of Q1 2025, 116 institutions reported holding Puma Biotechnology Inc. (PBYI) in their 13F filings, up 4 from Q4 2024. 23 opened new positions and 20 sold out. The largest holders were Acorn Capital Advisors, LLC ($11.7M), BlackRock, Inc. ($11.4M) and Vanguard Group Inc. ($10.9M). 4 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio).
- Company
- Puma Biotechnology Inc.
- CUSIP
- 74587V107
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 23 | $2.2M |
| Exits | 20 | $1.7M |
All 13F filers, Q4 2024 → Q1 2025: 3,110,396 shares bought and 2,093,414 shares sold, net +1,016,982 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 116 holders
| Acorn Capital Advisors, LLC | 7.78% | No change | 3,940,052 | $11.7M |
| BlackRock, Inc. | 0.00% | Add +0.6% | 3,847,368 | $11.4M |
| Vanguard Group Inc. | 0.00% | Add +0.7% | 3,669,263 | $10.9M |
| Acadian Asset Management LLC | 0.02% | Add +1.8% | 2,008,146 | $5.9M |
| Renaissance Technologies | 0.01% | Add +4.2% | 1,829,213 | $5.4M |
| Millennium Management | 0.00% | Reduce -26.9% | 1,385,194 | $4.1M |
| American Century Companies Inc. | 0.00% | Add +21.2% | 1,149,660 | $3.4M |
| Geode Capital Management, LLC | 0.00% | Add +3.9% | 955,456 | $2.8M |
| Kennedy Capital Management LLC | 0.06% | Add +12.6% | 911,123 | $2.7M |
| Dimensional Fund Advisors LP | 0.00% | Add +2.9% | 888,663 | $2.6M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.01% | Add +70.7% | 831,689 | $2.5M |
| State Street Corp. | 0.00% | Add +6.5% | 649,792 | $1.9M |
| D. E. Shaw & Co. | 0.00% | Add +156.8% | 571,665 | $1.7M |
| Globeflex Capital L P | 0.12% | No change | 452,606 | $1.3M |
| Los Angeles Capital Management LLC | 0.01% | Add +42.4% | 406,854 | $1.2M |
| Arrowstreet Capital, Limited Partnership | 0.00% | New | 358,621 | $1.1M |
| Sei Investments Co. | 0.00% | Add +11.6% | 347,679 | $1.0M |
| Bank of New York Mellon Corp | 0.00% | Add +2.7% | 340,886 | $1.0M |
| Northern Trust Corp. | 0.00% | Reduce -2.5% | 317,438 | $940K |
| Prudential Financial Inc. | 0.00% | Add +189.9% | 308,155 | $912K |
| Goldman Sachs Group Inc. | 0.00% | Reduce -6.3% | 294,243 | $871K |
| UBS Group AG | 0.00% | Add +79.8% | 279,667 | $828K |
| Eversept Partners, LP | 0.09% | Reduce -72.3% | 275,788 | $816K |
| Morgan Stanley | 0.00% | Reduce -2.9% | 262,538 | $777K |
| Two Sigma Advisers, LP | 0.00% | Add +25.3% | 246,800 | $731K |
| Marshall Wace, LLP | 0.00% | Add +152.9% | 216,413 | $641K |
| Federated Hermes, Inc. | 0.00% | Add +22.8% | 200,962 | $595K |
| Tang Capital Management LLC | 0.03% | No change | 200,000 | $592K |
| Two Sigma Investments, LP | 0.00% | Add +6.2% | 192,800 | $571K |
| Prospera Financial Services Inc | 0.01% | Add +3.6% | 184,257 | $545K |
| Mackenzie Financial Corp. | 0.00% | Add +100.5% | 157,713 | $467K |
| Qube Research & Technologies Ltd | 0.00% | Reduce -18.7% | 152,943 | $453K |
| STRS Ohio | 0.00% | Reduce -23.5% | 141,900 | $420K |
| FMR LLC | 0.00% | Reduce -3.5% | 127,174 | $376K |
| XTX Topco Ltd | 0.02% | Add +110.0% | 125,317 | $371K |
| Charles Schwab Investment Management Inc. | 0.00% | Add +0.5% | 118,254 | $350K |
| O'shaughnessy Asset Management, LLC | 0.00% | Reduce -4.1% | 107,945 | $320K |
| Gsa Capital Partners LLP | 0.03% | Reduce -8.4% | 99,394 | $294K |
| Bank of America Corp. | 0.00% | Add +13.1% | 93,087 | $276K |
| Royal Bank of Canada | 0.00% | Add +3.8% | 85,999 | $254K |
| Barclays PLC | 0.00% | Reduce -5.8% | 83,261 | $246K |
| Bridgeway Capital Management, LLC | 0.01% | Reduce -22.9% | 81,100 | $240K |
| Nuveen, LLC | 0.00% | — | 79,101 | $234K |
| Franklin Resources Inc. | 0.00% | Add +371.3% | 78,175 | $231K |
| BNP Paribas Financial Markets | 0.00% | Add +4.1% | 77,328 | $229K |
| Susquehanna International Group, LLP | 0.00% | Reduce -3.0% | 72,871 | $216K |
| Macquarie Group Ltd. | 0.00% | No change | 61,255 | $181K |
| Integrated Quantitative Investments LLC | 0.09% | Reduce -0.2% | 59,727 | $177K |
| Virtus Advisers, LLC | 0.11% | New | 55,431 | $164K |
| LSV Asset Management | 0.00% | No change | 53,400 | $158K |
| AQR Capital Management | 0.00% | Add +366.5% | 50,458 | $149K |
| JPMorgan Chase & Co. | 0.00% | Reduce -64.7% | 48,352 | $143K |
| LPL Financial LLC | 0.00% | Add +63.0% | 43,293 | $128K |
| Metis Global Partners, LLC | 0.00% | Add +8.2% | 42,758 | $127K |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | New | 39,308 | $116K |
| Rhumbline Advisers | 0.00% | Add +0.0% | 38,295 | $113K |
| Prelude Capital Management, LLC | 0.01% | Add +52.0% | 37,700 | $112K |
| Invesco Ltd. | 0.00% | Add +88.9% | 37,631 | $111K |
| Man Group plc | 0.00% | New | 37,469 | $111K |
| Virtu Financial LLC | 0.01% | New | 31,477 | $93K |
| Deutsche Bank AG | 0.00% | New | 30,743 | $91K |
| Intech Investment Management LLC | 0.00% | Add +52.3% | 30,504 | $90K |
| Citigroup Inc. | 0.00% | Reduce -11.4% | 29,467 | $87K |
| MetLife Investment Management, LLC | 0.00% | New | 27,121 | $80K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +4.6% | 24,857 | $74K |
| Bailard, Inc. | 0.00% | New | 24,702 | $73K |
| Wells Fargo & Company | 0.00% | Add +2.3% | 23,448 | $69K |
| Dynamic Technology Lab Private Ltd | 0.01% | New | 22,030 | $66K |
| Russell Investments Group, Ltd. | 0.00% | Add +104365.0% | 20,893 | $62K |
| Corebridge Financial, Inc. | 0.00% | Reduce -1.5% | 20,618 | $61K |
| HSBC Holdings PLC | 0.00% | New | 20,509 | $61K |
| PFG Investments, LLC | 0.00% | New | 20,000 | $59K |
| T. Rowe Price Associates Inc. | 0.00% | Add +2.5% | 19,566 | $58K |
| Royce & Associates LP | 0.00% | No change | 18,725 | $55K |
| Oxford Asset Management LLP | 0.02% | Reduce -24.9% | 17,647 | $52K |
| Osaic Holdings, Inc. | 0.00% | Add +2620.7% | 17,494 | $52K |
| Manufacturers Life Insurance Company, The | 0.00% | New | 16,506 | $49K |
| C2C Wealth Management, LLC | 0.04% | Add +26.3% | 15,150 | $45K |
| Williams & Novak, LLC | 0.04% | New | 14,720 | $43K |
| Causeway Capital Management LLC | 0.00% | New | 14,095 | $42K |
| Caprock Group, LLC | 0.00% | New | 13,817 | $41K |
| Walleye Capital LLC | 0.00% | Reduce -66.4% | 13,055 | $39K |
| Graham Capital Management, L.P. | 0.00% | Add +18.8% | 12,752 | $38K |
| Quadrature Capital Ltd | 0.00% | New | 12,508 | $37K |
| Voya Investment Management LLC | 0.00% | Reduce -16.3% | 12,366 | $37K |
| Sherbrooke Park Advisers LLC | 0.02% | New | 12,224 | $36K |
| Patriot Financial Group Insurance Agency, LLC | 0.00% | Reduce -12.5% | 10,500 | $31K |
| Gateway Wealth Partners, LLC | 0.01% | No change | 10,200 | $30K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 8,322 | $25K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 4,055 | $12K |
| Legal & General Group Plc | 0.00% | No change | 3,912 | $12K |
| New York State Common Retirement Fund | 0.00% | No change | 3,600 | $11K |
| Ball & Co Wealth Management Inc. | 0.01% | No change | 3,506 | $10K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -69.8% | 3,066 | $9K |
| Cwm, LLC | 0.00% | Add +174.1% | 3,012 | $9K |
| California State Teachers Retirement System | 0.00% | No change | 2,999 | $9K |
| Lazard Asset Management LLC | 0.00% | Reduce -15.8% | 2,100 | $6K |
| Private Wealth Asset Management, LLC | 0.00% | — | 2,000 | $6K |
| Rialto Wealth Management, LLC | 0.00% | New | 1,450 | $4K |
| Amalgamated Bank | 0.00% | No change | 1,432 | $4K |
| Headlands Technologies LLC | 0.00% | New | 1,217 | $4K |
| GHP Investment Advisors, Inc. | 0.00% | No change | 1,170 | $3K |
| GPS Wealth Strategies Group, LLC | 0.00% | No change | 1,000 | $3K |
| CIBC Private Wealth Group LLC | 0.00% | No change | 775 | $2K |
| Fourth Dimension Wealth, LLC | 0.00% | No change | 700 | $2K |
| Sterling Capital Management LLC | 0.00% | Reduce -45.5% | 505 | $1K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -15.9% | 417 | $1K |
| WealthCollab, LLC | 0.00% | New | 311 | $921 |
| Coldstream Capital Management Inc. | 0.00% | New | 304 | $900 |
| US Bancorp \de | 0.00% | No change | 200 | $592 |
| True Wealth Design, LLC | 0.00% | Add +491.7% | 142 | $421 |
| SouthState Bank Corp | 0.00% | New | 111 | $329 |
| SBI Securities Co., Ltd. | 0.00% | No change | 56 | $166 |
| IFP Advisors, Inc | 0.00% | No change | 14 | $41 |
| EverSource Wealth Advisors, LLC | 0.00% | New | 6 | $18 |
| Elevation Wealth Partners, LLC | 0.00% | No change | 3 | $9 |
"% of holder's portfolio" is PBYI's weight in each manager's 13F, not the share of Puma Biotechnology Inc. the manager owns.