Puma BiotechnologyPBYI

13F holders, Q2 2025 (June 30)
121holders +5
20new positions
16sold out
5famous investors
$3.43avg. 13F price*

At the end of Q2 2025, 121 institutions reported holding Puma Biotechnology Inc. (PBYI) in their 13F filings, up 5 from Q1 2025. 20 opened new positions and 16 sold out. The largest holders were Acorn Capital Advisors, LLC ($14.2M), BlackRock, Inc. ($13.2M) and Vanguard Group Inc. ($12.7M). 5 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).

Company
Puma Biotechnology Inc.
CUSIP
74587V107
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150200 Q1 2024: 93Q1 2024Q2 2024: 99Q2 2024Q3 2024: 100Q3 2024Q4 2024: 112Q4 2024Q1 2025: 116Q1 2025Q2 2025: 121Q2 2025Q3 2025: 132Q3 2025Q4 2025: 151Q4 2025Q1 2026: 157Q1 2026Q2 2026: 160Q2 2026

Total Exit/New Position Q1 2025 → Q2 2025

InstitutionsTotal Value
New Positions20$7.0M
Exits16$1.1M

All 13F filers, Q1 2025 → Q2 2025: 4,484,913 shares bought and 2,075,185 shares sold, net +2,409,728 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 121 holders

Acorn Capital Advisors, LLC 9.27% Add +4.8% 4,131,299 $14.2M
BlackRock, Inc. 0.00% Reduce -0.3% 3,835,715 $13.2M
Vanguard Group Inc. 0.00% Add +1.0% 3,706,452 $12.7M
Acadian Asset Management LLC 0.01% No change 2,008,146 $6.9M
Renaissance Technologies 0.01% Add +2.5% 1,874,713 $6.4M
American Century Companies Inc. 0.00% Add +16.8% 1,342,275 $4.6M
Dimensional Fund Advisors LP 0.00% Add +29.4% 1,150,040 $3.9M
Kennedy Capital Management LLC 0.08% Add +8.3% 987,001 $3.4M
Geode Capital Management, LLC 0.00% Add +1.7% 971,674 $3.3M
Connor, Clark & Lunn Investment Management Ltd. 0.01% Add +8.2% 900,256 $3.1M
Janus Henderson Group PLC 0.00% New 745,541 $2.6M
State Street Corp. 0.00% Add +13.1% 734,606 $2.5M
D. E. Shaw & Co. 0.00% Add +12.1% 640,780 $2.2M
LSV Asset Management 0.00% Add +903.3% 535,740 $1.8M
Citadel Advisors 0.00% New 507,818 $1.7M
Globeflex Capital L P 0.13% No change 452,606 $1.6M
Arrowstreet Capital, Limited Partnership 0.00% Add +25.9% 451,633 $1.5M
Los Angeles Capital Management LLC 0.01% Add +9.5% 445,477 $1.5M
O'shaughnessy Asset Management, LLC 0.01% Add +305.4% 437,660 $1.5M
Sei Investments Co. 0.00% Reduce -0.1% 347,234 $1.2M
Bank of New York Mellon Corp 0.00% Add +0.9% 344,083 $1.2M
Millennium Management 0.00% Reduce -75.8% 334,609 $1.1M
Morgan Stanley 0.00% Add +22.8% 322,462 $1.1M
Northern Trust Corp. 0.00% Reduce -4.9% 302,015 $1.0M
Prudential Financial Inc. 0.00% Reduce -8.7% 281,244 $965K
UBS Group AG 0.00% Reduce -2.0% 274,100 $940K
Two Sigma Advisers, LP 0.00% Reduce -0.5% 245,700 $843K
Eversept Partners, LP 0.08% Reduce -12.7% 240,688 $826K
Mackenzie Financial Corp. 0.00% Add +31.6% 207,591 $712K
Bridgeway Capital Management, LLC 0.02% Add +150.1% 202,790 $696K
Federated Hermes, Inc. 0.00% Add +0.7% 202,335 $694K
Goldman Sachs Group Inc. 0.00% Reduce -31.3% 202,029 $693K
Tang Capital Management LLC 0.03% No change 200,000 $686K
Ritholtz Wealth Management 0.01% New 196,985 $676K
Prospera Financial Services Inc 0.01% Add +3.8% 191,244 $656K
Two Sigma Investments, LP 0.00% Reduce -1.1% 190,621 $654K
STRS Ohio 0.00% Add +3.8% 147,300 $505K
AQR Capital Management 0.00% Add +181.0% 141,773 $486K
Qube Research & Technologies Ltd 0.00% Reduce -10.4% 137,079 $470K
FMR LLC 0.00% Add +4.1% 132,364 $454K
Charles Schwab Investment Management Inc. 0.00% Add +7.8% 127,443 $437K
Barclays PLC 0.00% Add +30.5% 108,653 $373K
XTX Topco Ltd 0.01% Reduce -16.7% 104,424 $358K
Evergreen Capital Management LLC 0.01% New 96,000 $329K
Hillsdale Investment Management Inc. 0.01% New 84,800 $291K
Nuveen, LLC 0.00% No change 79,101 $271K
Panagora Asset Management Inc. 0.00% New 76,684 $263K
Royal Bank of Canada 0.00% Reduce -10.9% 76,635 $262K
Marshall Wace, LLP 0.00% Reduce -66.1% 73,415 $252K
State Board of Administration of Florida Retirement System 0.00% New 71,727 $246K
Kapitalo Investimentos Ltda 0.05% New 70,269 $241K
Bank of America Corp. 0.00% Reduce -27.8% 67,242 $231K
Macquarie Group Ltd. 0.00% No change 61,255 $210K
Rhumbline Advisers 0.00% Add +58.3% 60,611 $208K
Susquehanna International Group, LLP 0.00% Reduce -20.8% 57,724 $198K
Metis Global Partners, LLC 0.00% Add +30.5% 55,798 $191K
Virtus Advisers, LLC 0.12% No change 55,431 $190K
LPL Financial LLC 0.00% Add +23.1% 53,293 $183K
Invesco Ltd. 0.00% Add +32.8% 49,982 $171K
Jane Street Group, LLC 0.00% New 39,448 $135K
Universal- Beteiligungs- und Servicegesellschaft mbH 0.00% No change 39,308 $135K
Empowered Funds, LLC 0.00% New 38,292 $131K
Prelude Capital Management, LLC 0.01% Reduce -11.3% 33,422 $115K
Deutsche Bank AG 0.00% No change 30,743 $105K
Wells Fargo & Company 0.00% Add +19.5% 28,026 $96K
MetLife Investment Management, LLC 0.00% Add +0.1% 27,158 $93K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Reduce -4.4% 23,765 $82K
Intech Investment Management LLC 0.00% Reduce -31.7% 20,823 $71K
C2C Wealth Management, LLC 0.06% Add +36.1% 20,620 $71K
JPMorgan Chase & Co. 0.00% Reduce -58.1% 20,245 $69K
Kathmere Capital Management, LLC 0.01% New 20,204 $69K
PFG Investments, LLC 0.00% No change 20,000 $69K
T. Rowe Price Associates Inc. 0.00% No change 19,566 $68K
HSBC Holdings PLC 0.00% Reduce -3.7% 19,751 $67K
Osaic Holdings, Inc. 0.00% Add +2.6% 17,944 $62K
Squarepoint Ops LLC 0.00% New 17,794 $61K
Franklin Resources Inc. 0.00% Reduce -77.4% 17,691 $61K
Royce & Associates LP 0.00% Reduce -7.7% 17,285 $59K
Manufacturers Life Insurance Company, The 0.00% Reduce -5.6% 15,576 $53K
D'Orazio & Associates, Inc. 0.01% New 15,027 $52K
Ethic Inc. 0.00% New 15,168 $51K
Citigroup Inc. 0.00% Reduce -51.4% 14,320 $49K
Ieq Capital, LLC 0.00% New 14,305 $49K
Causeway Capital Management LLC 0.00% No change 14,095 $48K
Alliancebernstein L.P. 0.00% New 13,800 $47K
Voya Investment Management LLC 0.00% Add +4.9% 12,976 $45K
Williams & Novak, LLC 0.04% Reduce -14.9% 12,520 $43K
Cerity Partners LLC 0.00% New 10,528 $36K
Cwm, LLC 0.00% Add +214.1% 9,462 $32K
Tower Research Capital LLC (TRC) 0.00% Add +176.2% 8,469 $29K
Police & Firemen's Retirement System of New Jersey 0.00% No change 8,322 $29K
BNP Paribas Financial Markets 0.00% Reduce -92.5% 5,766 $20K
Ameritas Investment Partners, Inc. 0.00% No change 4,055 $14K
New York State Common Retirement Fund 0.00% No change 3,600 $12K
Legal & General Group Plc 0.00% Reduce -8.9% 3,564 $12K
Private Wealth Asset Management, LLC 0.00% Add +75.0% 3,500 $12K
Ball & Co Wealth Management Inc. 0.01% No change 3,506 $12K
California State Teachers Retirement System 0.00% No change 2,999 $10K
Headlands Technologies LLC 0.00% Add +26.4% 1,538 $5K
Global Retirement Partners, LLC 0.00% — 1,492 $5K

"% of holder's portfolio" is PBYI's weight in each manager's 13F, not the share of Puma Biotechnology Inc. the manager owns.

Show all 121 holders