Puma BiotechnologyPBYI
13F holders, Q2 2025 (June 30)At the end of Q2 2025, 121 institutions reported holding Puma Biotechnology Inc. (PBYI) in their 13F filings, up 5 from Q1 2025. 20 opened new positions and 16 sold out. The largest holders were Acorn Capital Advisors, LLC ($14.2M), BlackRock, Inc. ($13.2M) and Vanguard Group Inc. ($12.7M). 5 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Puma Biotechnology Inc.
- CUSIP
- 74587V107
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 20 | $7.0M |
| Exits | 16 | $1.1M |
All 13F filers, Q1 2025 → Q2 2025: 4,484,913 shares bought and 2,075,185 shares sold, net +2,409,728 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 121 holders
| Acorn Capital Advisors, LLC | 9.27% | Add +4.8% | 4,131,299 | $14.2M |
| BlackRock, Inc. | 0.00% | Reduce -0.3% | 3,835,715 | $13.2M |
| Vanguard Group Inc. | 0.00% | Add +1.0% | 3,706,452 | $12.7M |
| Acadian Asset Management LLC | 0.01% | No change | 2,008,146 | $6.9M |
| Renaissance Technologies | 0.01% | Add +2.5% | 1,874,713 | $6.4M |
| American Century Companies Inc. | 0.00% | Add +16.8% | 1,342,275 | $4.6M |
| Dimensional Fund Advisors LP | 0.00% | Add +29.4% | 1,150,040 | $3.9M |
| Kennedy Capital Management LLC | 0.08% | Add +8.3% | 987,001 | $3.4M |
| Geode Capital Management, LLC | 0.00% | Add +1.7% | 971,674 | $3.3M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.01% | Add +8.2% | 900,256 | $3.1M |
| Janus Henderson Group PLC | 0.00% | New | 745,541 | $2.6M |
| State Street Corp. | 0.00% | Add +13.1% | 734,606 | $2.5M |
| D. E. Shaw & Co. | 0.00% | Add +12.1% | 640,780 | $2.2M |
| LSV Asset Management | 0.00% | Add +903.3% | 535,740 | $1.8M |
| Citadel Advisors | 0.00% | New | 507,818 | $1.7M |
| Globeflex Capital L P | 0.13% | No change | 452,606 | $1.6M |
| Arrowstreet Capital, Limited Partnership | 0.00% | Add +25.9% | 451,633 | $1.5M |
| Los Angeles Capital Management LLC | 0.01% | Add +9.5% | 445,477 | $1.5M |
| O'shaughnessy Asset Management, LLC | 0.01% | Add +305.4% | 437,660 | $1.5M |
| Sei Investments Co. | 0.00% | Reduce -0.1% | 347,234 | $1.2M |
| Bank of New York Mellon Corp | 0.00% | Add +0.9% | 344,083 | $1.2M |
| Millennium Management | 0.00% | Reduce -75.8% | 334,609 | $1.1M |
| Morgan Stanley | 0.00% | Add +22.8% | 322,462 | $1.1M |
| Northern Trust Corp. | 0.00% | Reduce -4.9% | 302,015 | $1.0M |
| Prudential Financial Inc. | 0.00% | Reduce -8.7% | 281,244 | $965K |
| UBS Group AG | 0.00% | Reduce -2.0% | 274,100 | $940K |
| Two Sigma Advisers, LP | 0.00% | Reduce -0.5% | 245,700 | $843K |
| Eversept Partners, LP | 0.08% | Reduce -12.7% | 240,688 | $826K |
| Mackenzie Financial Corp. | 0.00% | Add +31.6% | 207,591 | $712K |
| Bridgeway Capital Management, LLC | 0.02% | Add +150.1% | 202,790 | $696K |
| Federated Hermes, Inc. | 0.00% | Add +0.7% | 202,335 | $694K |
| Goldman Sachs Group Inc. | 0.00% | Reduce -31.3% | 202,029 | $693K |
| Tang Capital Management LLC | 0.03% | No change | 200,000 | $686K |
| Ritholtz Wealth Management | 0.01% | New | 196,985 | $676K |
| Prospera Financial Services Inc | 0.01% | Add +3.8% | 191,244 | $656K |
| Two Sigma Investments, LP | 0.00% | Reduce -1.1% | 190,621 | $654K |
| STRS Ohio | 0.00% | Add +3.8% | 147,300 | $505K |
| AQR Capital Management | 0.00% | Add +181.0% | 141,773 | $486K |
| Qube Research & Technologies Ltd | 0.00% | Reduce -10.4% | 137,079 | $470K |
| FMR LLC | 0.00% | Add +4.1% | 132,364 | $454K |
| Charles Schwab Investment Management Inc. | 0.00% | Add +7.8% | 127,443 | $437K |
| Barclays PLC | 0.00% | Add +30.5% | 108,653 | $373K |
| XTX Topco Ltd | 0.01% | Reduce -16.7% | 104,424 | $358K |
| Evergreen Capital Management LLC | 0.01% | New | 96,000 | $329K |
| Hillsdale Investment Management Inc. | 0.01% | New | 84,800 | $291K |
| Nuveen, LLC | 0.00% | No change | 79,101 | $271K |
| Panagora Asset Management Inc. | 0.00% | New | 76,684 | $263K |
| Royal Bank of Canada | 0.00% | Reduce -10.9% | 76,635 | $262K |
| Marshall Wace, LLP | 0.00% | Reduce -66.1% | 73,415 | $252K |
| State Board of Administration of Florida Retirement System | 0.00% | New | 71,727 | $246K |
| Kapitalo Investimentos Ltda | 0.05% | New | 70,269 | $241K |
| Bank of America Corp. | 0.00% | Reduce -27.8% | 67,242 | $231K |
| Macquarie Group Ltd. | 0.00% | No change | 61,255 | $210K |
| Rhumbline Advisers | 0.00% | Add +58.3% | 60,611 | $208K |
| Susquehanna International Group, LLP | 0.00% | Reduce -20.8% | 57,724 | $198K |
| Metis Global Partners, LLC | 0.00% | Add +30.5% | 55,798 | $191K |
| Virtus Advisers, LLC | 0.12% | No change | 55,431 | $190K |
| LPL Financial LLC | 0.00% | Add +23.1% | 53,293 | $183K |
| Invesco Ltd. | 0.00% | Add +32.8% | 49,982 | $171K |
| Jane Street Group, LLC | 0.00% | New | 39,448 | $135K |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | No change | 39,308 | $135K |
| Empowered Funds, LLC | 0.00% | New | 38,292 | $131K |
| Prelude Capital Management, LLC | 0.01% | Reduce -11.3% | 33,422 | $115K |
| Deutsche Bank AG | 0.00% | No change | 30,743 | $105K |
| Wells Fargo & Company | 0.00% | Add +19.5% | 28,026 | $96K |
| MetLife Investment Management, LLC | 0.00% | Add +0.1% | 27,158 | $93K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -4.4% | 23,765 | $82K |
| Intech Investment Management LLC | 0.00% | Reduce -31.7% | 20,823 | $71K |
| C2C Wealth Management, LLC | 0.06% | Add +36.1% | 20,620 | $71K |
| JPMorgan Chase & Co. | 0.00% | Reduce -58.1% | 20,245 | $69K |
| Kathmere Capital Management, LLC | 0.01% | New | 20,204 | $69K |
| PFG Investments, LLC | 0.00% | No change | 20,000 | $69K |
| T. Rowe Price Associates Inc. | 0.00% | No change | 19,566 | $68K |
| HSBC Holdings PLC | 0.00% | Reduce -3.7% | 19,751 | $67K |
| Osaic Holdings, Inc. | 0.00% | Add +2.6% | 17,944 | $62K |
| Squarepoint Ops LLC | 0.00% | New | 17,794 | $61K |
| Franklin Resources Inc. | 0.00% | Reduce -77.4% | 17,691 | $61K |
| Royce & Associates LP | 0.00% | Reduce -7.7% | 17,285 | $59K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -5.6% | 15,576 | $53K |
| D'Orazio & Associates, Inc. | 0.01% | New | 15,027 | $52K |
| Ethic Inc. | 0.00% | New | 15,168 | $51K |
| Citigroup Inc. | 0.00% | Reduce -51.4% | 14,320 | $49K |
| Ieq Capital, LLC | 0.00% | New | 14,305 | $49K |
| Causeway Capital Management LLC | 0.00% | No change | 14,095 | $48K |
| Alliancebernstein L.P. | 0.00% | New | 13,800 | $47K |
| Voya Investment Management LLC | 0.00% | Add +4.9% | 12,976 | $45K |
| Williams & Novak, LLC | 0.04% | Reduce -14.9% | 12,520 | $43K |
| Cerity Partners LLC | 0.00% | New | 10,528 | $36K |
| Cwm, LLC | 0.00% | Add +214.1% | 9,462 | $32K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +176.2% | 8,469 | $29K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 8,322 | $29K |
| BNP Paribas Financial Markets | 0.00% | Reduce -92.5% | 5,766 | $20K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 4,055 | $14K |
| New York State Common Retirement Fund | 0.00% | No change | 3,600 | $12K |
| Legal & General Group Plc | 0.00% | Reduce -8.9% | 3,564 | $12K |
| Private Wealth Asset Management, LLC | 0.00% | Add +75.0% | 3,500 | $12K |
| Ball & Co Wealth Management Inc. | 0.01% | No change | 3,506 | $12K |
| California State Teachers Retirement System | 0.00% | No change | 2,999 | $10K |
| Headlands Technologies LLC | 0.00% | Add +26.4% | 1,538 | $5K |
| Global Retirement Partners, LLC | 0.00% | — | 1,492 | $5K |
"% of holder's portfolio" is PBYI's weight in each manager's 13F, not the share of Puma Biotechnology Inc. the manager owns.