Puma BiotechnologyPBYI
13F holders, Q3 2025 (September 30)132holders +11
22new positions
12sold out
4famous investors
$5.31avg. 13F price*
At the end of Q3 2025, 132 institutions reported holding Puma Biotechnology Inc. (PBYI) in their 13F filings, up 11 from Q2 2025. 22 opened new positions and 12 sold out. The largest holders were Acorn Capital Advisors, LLC ($21.9M), Vanguard Group Inc. ($19.6M) and BlackRock, Inc. ($19.0M). 4 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Puma Biotechnology Inc.
- CUSIP
- 74587V107
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 22 | $4.2M |
| Exits | 12 | $6.0M |
All 13F filers, Q2 2025 → Q3 2025: 4,960,436 shares bought and 3,403,043 shares sold, net +1,557,393 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 132 holders
| Acorn Capital Advisors, LLC | 11.14% | No change | 4,131,299 | $21.9M |
| Vanguard Group Inc. | 0.00% | Reduce -0.4% | 3,691,720 | $19.6M |
| BlackRock, Inc. | 0.00% | Reduce -6.7% | 3,577,877 | $19.0M |
| Renaissance Technologies | 0.02% | Add +14.8% | 2,151,213 | $11.4M |
| Acadian Asset Management LLC | 0.02% | Add +2.3% | 2,053,305 | $10.9M |
| American Century Companies Inc. | 0.00% | Add +10.5% | 1,483,188 | $7.9M |
| Dimensional Fund Advisors LP | 0.00% | Add +10.6% | 1,271,878 | $6.8M |
| Geode Capital Management, LLC | 0.00% | Add +1.2% | 983,522 | $5.2M |
| Russell Investments Group, Ltd. | 0.01% | Add +4823365.0% | 964,693 | $5.1M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.02% | Add +4.8% | 943,472 | $5.0M |
| Kennedy Capital Management LLC | 0.10% | Reduce -12.1% | 867,630 | $4.6M |
| O'shaughnessy Asset Management, LLC | 0.03% | Add +89.2% | 828,221 | $4.4M |
| State Street Corp. | 0.00% | Add +1.9% | 748,658 | $4.0M |
| LSV Asset Management | 0.01% | Add +4.5% | 559,921 | $3.0M |
| Marshall Wace, LLP | 0.00% | Add +659.5% | 557,548 | $3.0M |
| Northern Trust Corp. | 0.00% | Add +74.4% | 526,736 | $2.8M |
| D. E. Shaw & Co. | 0.00% | Reduce -22.2% | 498,598 | $2.6M |
| Ritholtz Wealth Management | 0.05% | Add +139.0% | 470,767 | $2.5M |
| Arrowstreet Capital, Limited Partnership | 0.00% | Add +2.9% | 464,734 | $2.5M |
| Globeflex Capital L P | 0.37% | No change | 452,606 | $2.4M |
| Bridgeway Capital Management, LLC | 0.05% | Add +113.8% | 433,561 | $2.3M |
| Morgan Stanley | 0.00% | Add +17.3% | 378,082 | $2.0M |
| UBS Group AG | 0.00% | Add +37.2% | 376,091 | $2.0M |
| Bank of New York Mellon Corp | 0.00% | Add +3.3% | 355,368 | $1.9M |
| Sei Investments Co. | 0.00% | No change | 347,234 | $1.8M |
| Los Angeles Capital Management LLC | 0.00% | Reduce -38.5% | 274,050 | $1.5M |
| Goldman Sachs Group Inc. | 0.00% | Add +16.1% | 234,617 | $1.2M |
| Prudential Financial Inc. | 0.00% | Reduce -21.4% | 220,944 | $1.2M |
| Tang Capital Management LLC | 0.04% | No change | 200,000 | $1.1M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | Add +405.0% | 198,508 | $1.1M |
| Federated Hermes, Inc. | 0.00% | Reduce -2.1% | 197,981 | $1.1M |
| Prospera Financial Services Inc | 0.02% | Reduce -0.8% | 189,619 | $1.0M |
| Mackenzie Financial Corp. | 0.00% | Reduce -15.6% | 175,210 | $930K |
| Franklin Resources Inc. | 0.00% | Add +881.8% | 173,698 | $922K |
| Panagora Asset Management Inc. | 0.00% | Add +116.4% | 165,921 | $881K |
| Qube Research & Technologies Ltd | 0.00% | Add +13.4% | 155,516 | $826K |
| Wellington Management Group LLP | 0.00% | New | 149,552 | $794K |
| FMR LLC | 0.00% | Add +9.8% | 145,285 | $771K |
| Jane Street Group, LLC | 0.00% | Add +251.2% | 138,542 | $736K |
| AQR Capital Management | 0.00% | Reduce -7.8% | 130,672 | $694K |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -1.6% | 125,372 | $666K |
| STRS Ohio | 0.00% | Reduce -15.2% | 124,900 | $663K |
| First Trust Advisors LP | 0.00% | New | 119,779 | $636K |
| Empowered Funds, LLC | 0.01% | Add +212.2% | 119,561 | $635K |
| Millennium Management | 0.00% | Reduce -68.4% | 105,633 | $561K |
| Evergreen Capital Management LLC | 0.01% | No change | 96,000 | $510K |
| Barclays PLC | 0.00% | Reduce -26.5% | 79,881 | $424K |
| Nuveen, LLC | 0.00% | No change | 79,101 | $420K |
| Hillsdale Investment Management Inc. | 0.01% | Reduce -8.3% | 77,800 | $413K |
| Two Sigma Advisers, LP | 0.00% | Reduce -70.2% | 73,200 | $389K |
| Assenagon Asset Management S.A. | 0.00% | New | 72,979 | $388K |
| Invesco Ltd. | 0.00% | Add +27.7% | 63,817 | $339K |
| Lazard Asset Management LLC | 0.00% | New | 63,147 | $335K |
| Round Rock Advisors LLC | 0.05% | New | 65,396 | $330K |
| WINTON GROUP Ltd | 0.01% | New | 61,324 | $326K |
| Macquarie Group Ltd. | 0.00% | No change | 61,255 | $325K |
| Rhumbline Advisers | 0.00% | Reduce -1.0% | 60,001 | $319K |
| Two Sigma Investments, LP | 0.00% | Reduce -70.6% | 56,126 | $298K |
| Metis Global Partners, LLC | 0.01% | No change | 55,798 | $296K |
| State of Wisconsin Investment Board | 0.00% | New | 54,318 | $288K |
| Graham Capital Management, L.P. | 0.02% | New | 52,708 | $280K |
| LPL Financial LLC | 0.00% | Reduce -3.7% | 51,303 | $272K |
| Cambridge Investment Research Advisors, Inc. | 0.00% | New | 50,823 | $270K |
| Virtus Advisers, LLC | 0.14% | Reduce -14.9% | 47,172 | $250K |
| Bank of America Corp. | 0.00% | Reduce -33.1% | 44,967 | $239K |
| Prelude Capital Management, LLC | 0.02% | Add +15.0% | 38,422 | $204K |
| Wells Fargo & Company | 0.00% | Add +16.1% | 32,531 | $173K |
| D'Orazio & Associates, Inc. | 0.02% | Add +112.5% | 31,933 | $170K |
| Deutsche Bank AG | 0.00% | No change | 30,743 | $163K |
| Sherbrooke Park Advisers LLC | 0.08% | New | 30,527 | $162K |
| Headlands Technologies LLC | 0.01% | Add +1796.9% | 29,174 | $155K |
| Kathmere Capital Management, LLC | 0.01% | Add +38.4% | 27,953 | $148K |
| XTX Topco Ltd | 0.01% | Reduce -75.6% | 25,524 | $136K |
| Sanctuary Advisors, LLC | 0.00% | New | 23,866 | $127K |
| C2C Wealth Management, LLC | 0.10% | Add +11.6% | 23,020 | $122K |
| Baron Wealth Management LLC | 0.04% | New | 21,767 | $116K |
| T. Rowe Price Associates Inc. | 0.00% | Add +10.5% | 21,625 | $115K |
| Squarepoint Ops LLC | 0.00% | Add +19.9% | 21,334 | $113K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -14.9% | 20,223 | $107K |
| Intech Investment Management LLC | 0.00% | Reduce -9.2% | 18,900 | $100K |
| Royce & Associates LP | 0.00% | Add +8.3% | 18,725 | $99K |
| Osaic Holdings, Inc. | 0.00% | Add +1.8% | 18,263 | $96K |
| JPMorgan Chase & Co. | 0.00% | Reduce -14.6% | 17,285 | $92K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -2.7% | 15,157 | $80K |
| PFG Investments, LLC | 0.00% | Reduce -25.0% | 15,000 | $80K |
| MetLife Investment Management, LLC | 0.00% | Reduce -46.4% | 14,545 | $77K |
| Causeway Capital Management LLC | 0.00% | No change | 14,095 | $75K |
| Alliancebernstein L.P. | 0.00% | No change | 13,800 | $73K |
| State of Wyoming | 0.01% | New | 12,737 | $68K |
| Perkins Capital Management Inc. | 0.06% | New | 12,200 | $65K |
| Caprock Group, LLC | 0.00% | — | 11,768 | $59K |
| Ethic Inc. | 0.00% | Reduce -31.7% | 10,353 | $55K |
| Cerity Partners LLC | 0.00% | Reduce -3.0% | 10,210 | $54K |
| Cwm, LLC | 0.00% | Reduce -5.7% | 8,920 | $47K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 8,322 | $44K |
| BNP Paribas Financial Markets | 0.00% | Add +39.7% | 8,056 | $43K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 4,055 | $22K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -54.2% | 3,879 | $21K |
| New York State Common Retirement Fund | 0.00% | No change | 3,600 | $19K |
| Legal & General Group Plc | 0.00% | No change | 3,564 | $19K |
"% of holder's portfolio" is PBYI's weight in each manager's 13F, not the share of Puma Biotechnology Inc. the manager owns.