Prime MedicinePRME
13F holders, Q1 2025 (March 31)125holders −7
22new positions
29sold out
5famous investors
$1.99avg. 13F price*
At the end of Q1 2025, 125 institutions reported holding Prime Medicine Inc. (PRME) in their 13F filings, down 7 from Q4 2024. 22 opened new positions and 29 sold out. The largest holders were Alphabet Inc. ($30.0M), BlackRock, Inc. ($8.6M) and T. Rowe Price Investment Management, Inc. ($8.2M). 5 famous investors held it, including Cathie Wood (0.1% of ARK Investment Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).
- Company
- Prime Medicine Inc.
- CUSIP
- 74168J101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 22 | $1.8M |
| Exits | 29 | $6.1M |
All 13F filers, Q4 2024 → Q1 2025: 2,071,219 shares bought and 5,688,717 shares sold, net −3,617,498 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 125 holders
| Alphabet Inc. | 1.90% | No change | 15,062,498 | $30.0M |
| BlackRock, Inc. | 0.00% | Reduce -4.8% | 4,306,211 | $8.6M |
| T. Rowe Price Investment Management, Inc. | 0.01% | Add +4.2% | 4,143,096 | $8.2M |
| FMR LLC | 0.00% | Reduce -1.4% | 3,747,235 | $7.5M |
| Vanguard Group Inc. | 0.00% | Reduce -0.4% | 3,641,348 | $7.2M |
| ARK Investment Management | 0.06% | Reduce -39.9% | 3,095,172 | $6.2M |
| Amova Asset Management Americas, Inc. | 0.08% | Reduce -5.3% | 2,926,023 | $5.8M |
| Sumitomo Mitsui Trust Group, Inc. | 0.00% | Reduce -5.3% | 2,926,023 | $5.8M |
| Redmile Group, LLC | 0.39% | No change | 2,074,350 | $4.1M |
| MWG Management Ltd. | 6.08% | No change | 1,792,210 | $3.6M |
| Millennium Management | 0.00% | Reduce -5.0% | 1,779,945 | $3.5M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -1.1% | 1,567,192 | $3.1M |
| Geode Capital Management, LLC | 0.00% | Add +4.0% | 1,526,530 | $3.0M |
| State Street Corp. | 0.00% | Reduce -0.8% | 1,145,305 | $2.3M |
| Baker Bros. Advisors LP | 0.02% | No change | 1,028,466 | $2.0M |
| Greenwich Wealth Management LLC | 0.12% | Add +5.8% | 819,001 | $1.6M |
| Farallon Capital Management, L.L.C. | 0.01% | No change | 750,000 | $1.5M |
| EcoR1 Capital, LLC | 0.08% | No change | 700,000 | $1.4M |
| Northern Trust Corp. | 0.00% | Reduce -3.2% | 527,309 | $1.0M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +3.9% | 503,697 | $1.0M |
| Moore Capital Management, LP | 0.04% | No change | 500,000 | $995K |
| Renaissance Technologies | 0.00% | New | 447,600 | $891K |
| Samsara Biocapital, LLC | 0.14% | No change | 405,228 | $806K |
| Casdin Capital, LLC | 0.06% | No change | 367,175 | $731K |
| Bollard Group LLC | 0.02% | No change | 361,136 | $719K |
| Morgan Stanley | 0.00% | Add +14.1% | 355,176 | $707K |
| Two Sigma Investments, LP | 0.00% | Add +55.7% | 258,770 | $515K |
| Goldman Sachs Group Inc. | 0.00% | Reduce -40.4% | 251,399 | $500K |
| AQR Capital Management | 0.00% | Add +1419.3% | 243,795 | $485K |
| Chelsea Counsel Co. | 0.23% | Add +11.5% | 208,210 | $414K |
| Nuveen, LLC | 0.00% | — | 59,402 | $374K |
| Bank of New York Mellon Corp | 0.00% | Add +20.4% | 155,992 | $310K |
| Gsa Capital Partners LLP | 0.03% | Add +901.1% | 153,273 | $305K |
| Susquehanna International Group, LLP | 0.00% | Add +284.9% | 142,619 | $284K |
| Deutsche Bank AG | 0.00% | Add +56.9% | 126,846 | $252K |
| FIL Ltd | 0.00% | No change | 121,017 | $241K |
| UBS Group AG | 0.00% | Reduce -46.1% | 117,680 | $234K |
| Bank of America Corp. | 0.00% | Reduce -73.8% | 112,926 | $225K |
| Palumbo Wealth Management LLC | 0.06% | New | 95,462 | $190K |
| Wells Fargo & Company | 0.00% | Reduce -5.6% | 90,819 | $181K |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd | 0.02% | Add +48.1% | 89,870 | $179K |
| Green Alpha Advisors, LLC | 0.18% | Add +29.6% | 83,467 | $166K |
| Rhumbline Advisers | 0.00% | Add +13.8% | 81,900 | $163K |
| Vestmark Advisory Solutions, Inc. | 0.00% | Reduce -29.5% | 78,599 | $156K |
| Alliancebernstein L.P. | 0.00% | No change | 76,000 | $151K |
| Barclays PLC | 0.00% | Reduce -26.8% | 71,424 | $142K |
| Tudor Investment Corporation | 0.00% | New | 60,368 | $120K |
| Intech Investment Management LLC | 0.00% | Add +80.7% | 54,946 | $109K |
| Virtus Investment Advisers, LLC | 0.03% | New | 54,535 | $109K |
| Two Sigma Advisers, LP | 0.00% | Add +24.8% | 53,900 | $107K |
| SG Americas Securities, LLC | 0.00% | Reduce -14.6% | 51,456 | $102K |
| Jacobs Levy Equity Management, Inc. | 0.00% | New | 50,514 | $101K |
| TD Asset Management Inc | 0.00% | No change | 46,434 | $92K |
| Citigroup Inc. | 0.00% | Reduce -10.8% | 42,302 | $84K |
| Brooklyn Investment Group | 0.02% | Add +2010.2% | 39,967 | $80K |
| Verition Fund Management LLC | 0.00% | Reduce -63.0% | 38,255 | $76K |
| JPMorgan Chase & Co. | 0.00% | Add +0.1% | 35,663 | $71K |
| Levin Capital Strategies, L.P. | 0.01% | Reduce -53.3% | 35,000 | $70K |
| Ieq Capital, LLC | 0.00% | New | 34,882 | $69K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +4.4% | 33,918 | $67K |
| Crestwood Advisors Group, LLC | 0.00% | No change | 31,687 | $63K |
| Cerity Partners LLC | 0.00% | New | 31,387 | $62K |
| BNP Paribas Financial Markets | 0.00% | Add +55.9% | 31,322 | $62K |
| Brevan Howard Capital Management LP | 0.00% | New | 28,478 | $57K |
| Corebridge Financial, Inc. | 0.00% | Reduce -1.5% | 27,785 | $55K |
| China Universal Asset Management Co., Ltd. | 0.00% | Reduce -5.4% | 26,309 | $52K |
| Quadrature Capital Ltd | 0.00% | New | 24,802 | $50K |
| Manufacturers Life Insurance Company, The | 0.00% | Add +5.7% | 24,924 | $50K |
| Prime Capital Investment Advisors, LLC | 0.00% | Add +1.3% | 24,261 | $48K |
| Sanctuary Advisors, LLC | 0.00% | New | 23,822 | $47K |
| Envestnet Asset Management Inc. | 0.00% | Add +9.1% | 23,515 | $47K |
| HighTower Advisors, LLC | 0.00% | Add +0.3% | 21,646 | $43K |
| Avanza Fonder AB | 0.00% | Add +6.4% | 23,918 | $43K |
| Benjamin Edwards Inc. | 0.00% | Reduce -3.7% | 21,101 | $42K |
| Cwm, LLC | 0.00% | Add +741.5% | 20,466 | $41K |
| ProShare Advisors LLC | 0.00% | Reduce -18.0% | 18,194 | $36K |
| Voya Investment Management LLC | 0.00% | Reduce -5.2% | 17,222 | $34K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 17,092 | $34K |
| Cibc World Market Inc. | 0.00% | Reduce -10.6% | 17,015 | $34K |
| Clarius Group, LLC | 0.00% | No change | 16,080 | $32K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Add +23.1% | 15,237 | $30K |
| Invesco Ltd. | 0.00% | Reduce -1.6% | 14,836 | $30K |
| Cibc World Markets Corp. | 0.00% | New | 12,585 | $25K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | New | 12,230 | $24K |
| American Century Companies Inc. | 0.00% | No change | 11,426 | $23K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 11,420 | $23K |
| Pathstone Holdings, LLC | 0.00% | Reduce -0.5% | 11,250 | $22K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +609.3% | 9,909 | $20K |
| Farther Finance Advisors, LLC | 0.00% | Add +41296.2% | 10,763 | $19K |
| New York State Common Retirement Fund | 0.00% | No change | 8,434 | $17K |
| Simplex Trading, LLC | 0.00% | Add +474.5% | 8,376 | $16K |
| Legal & General Group Plc | 0.00% | Reduce -5.8% | 5,915 | $12K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +0.4% | 4,389 | $9K |
| California State Teachers Retirement System | 0.00% | No change | 4,110 | $8K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 3,901 | $8K |
| GF Fund Management Co. LTD. | 0.00% | Add +24.4% | 3,358 | $7K |
| Signaturefd, LLC | 0.00% | Add +60.3% | 2,649 | $5K |
| Amalgamated Bank | 0.00% | Add +45.3% | 1,957 | $4K |
| Quadrant Capital Group LLC | 0.00% | Add +121.1% | 1,842 | $4K |
| Royal Bank of Canada | 0.00% | Add +41.1% | 1,640 | $3K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +16766.7% | 1,012 | $2K |
| First Horizon Advisors, Inc. | 0.00% | Reduce -16.0% | 932 | $2K |
| Leonteq Securities AG | 0.00% | New | 915 | $2K |
| Fairman Group, LLC | 0.00% | No change | 500 | $1K |
| Rise Advisors, LLC | 0.00% | New | 575 | $1K |
| SBI Securities Co., Ltd. | 0.00% | Reduce -52.4% | 574 | $1K |
| Daiwa Securities Group Inc. | 0.00% | No change | 398 | $1K |
| Prestige Wealth Management Group LLC | 0.00% | New | 434 | $864 |
| Hughes Financial Services, LLC | 0.00% | New | 480 | $857 |
| Principal Securities, Inc. | 0.00% | No change | 280 | $818 |
| PNC Financial Services Group, Inc. | 0.00% | Add +121.9% | 324 | $645 |
| Comerica Bank | 0.00% | Reduce -70.6% | 315 | $628 |
| Rothschild Investment LLC | 0.00% | Add +12.5% | 315 | $627 |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -97.5% | 315 | $627 |
| Coldstream Capital Management Inc. | 0.00% | New | 283 | $564 |
| Larson Financial Group LLC | 0.00% | New | 200 | $398 |
| Osaic Holdings, Inc. | 0.00% | Reduce -57.7% | 164 | $324 |
| Parallel Advisors, LLC | 0.00% | New | 110 | $219 |
| Sterling Capital Management LLC | 0.00% | No change | 58 | $115 |
| Russell Investments Group, Ltd. | 0.00% | Reduce -86.6% | 52 | $103 |
| True Wealth Design, LLC | 0.00% | New | 50 | $100 |
| Cordant, Inc. | 0.00% | New | 33 | $66 |
| IFP Advisors, Inc | 0.00% | No change | 24 | $48 |
| Avion Wealth | 0.00% | New | 178 | $0 |
| Covestor Ltd | 0.00% | Add +135.7% | 33 | $0 |
"% of holder's portfolio" is PRME's weight in each manager's 13F, not the share of Prime Medicine Inc. the manager owns.