Prime MedicinePRME
13F holders, Q2 2025 (June 30)121holders −4
28new positions
33sold out
5famous investors
$2.47avg. 13F price*
At the end of Q2 2025, 121 institutions reported holding Prime Medicine Inc. (PRME) in their 13F filings, down 4 from Q1 2025. 28 opened new positions and 33 sold out. The largest holders were Alphabet Inc. ($37.2M), T. Rowe Price Investment Management, Inc. ($16.0M) and BlackRock, Inc. ($11.1M). 5 famous investors held it, including Cathie Wood (0.0% of ARK Investment Management's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Cliff Asness (0.0% of AQR Capital Management's portfolio).
- Company
- Prime Medicine Inc.
- CUSIP
- 74168J101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 28 | $6.8M |
| Exits | 33 | $5.8M |
All 13F filers, Q1 2025 → Q2 2025: 8,287,336 shares bought and 9,986,541 shares sold, net −1,699,205 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 121 holders
| Alphabet Inc. | 1.74% | No change | 15,062,498 | $37.2M |
| T. Rowe Price Investment Management, Inc. | 0.01% | Add +56.5% | 6,484,787 | $16.0M |
| BlackRock, Inc. | 0.00% | Add +4.2% | 4,485,828 | $11.1M |
| FMR LLC | 0.00% | Reduce -0.1% | 3,744,427 | $9.2M |
| Vanguard Group Inc. | 0.00% | Reduce -0.4% | 3,627,510 | $9.0M |
| ARK Investment Management | 0.04% | Reduce -25.0% | 2,322,669 | $5.7M |
| Redmile Group, LLC | 0.55% | No change | 2,074,350 | $5.1M |
| MWG Management Ltd. | 8.53% | No change | 1,792,210 | $4.4M |
| Sumitomo Mitsui Trust Group, Inc. | 0.00% | Reduce -45.5% | 1,594,518 | $3.9M |
| Amova Asset Management Americas, Inc. | 0.04% | Reduce -45.7% | 1,589,117 | $3.9M |
| Casdin Capital, LLC | 0.35% | Add +326.8% | 1,567,175 | $3.9M |
| Geode Capital Management, LLC | 0.00% | Reduce -1.0% | 1,510,749 | $3.7M |
| State Street Corp. | 0.00% | Add +8.2% | 1,239,337 | $3.1M |
| Greenwich Wealth Management LLC | 0.10% | Add +3.3% | 846,201 | $2.1M |
| Schonfeld Strategic Advisors LLC | 0.02% | New | 818,518 | $2.0M |
| Farallon Capital Management, L.L.C. | 0.01% | No change | 750,000 | $1.9M |
| Morgan Stanley | 0.00% | Add +65.5% | 587,676 | $1.5M |
| Citadel Advisors | 0.00% | New | 521,508 | $1.3M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +3.0% | 518,628 | $1.3M |
| Northern Trust Corp. | 0.00% | Reduce -2.9% | 512,234 | $1.3M |
| Moore Capital Management, LP | 0.03% | No change | 500,000 | $1.2M |
| Susquehanna International Group, LLP | 0.00% | Add +238.5% | 482,728 | $1.2M |
| AQR Capital Management | 0.00% | Add +74.1% | 424,355 | $1.0M |
| Fred Alger Management, LLC | 0.00% | New | 383,194 | $946K |
| Bollard Group LLC | 0.02% | No change | 361,136 | $892K |
| Two Sigma Investments, LP | 0.00% | Reduce -0.1% | 258,423 | $638K |
| Renaissance Technologies | 0.00% | Reduce -50.1% | 223,400 | $552K |
| Bridgeway Capital Management, LLC | 0.01% | New | 214,800 | $531K |
| Chelsea Counsel Co. | 0.26% | No change | 208,210 | $514K |
| Nuveen, LLC | 0.00% | Add +250.0% | 207,894 | $513K |
| Goldman Sachs Group Inc. | 0.00% | Reduce -17.7% | 207,008 | $511K |
| UBS Group AG | 0.00% | Add +66.0% | 195,327 | $482K |
| Simplex Trading, LLC | 0.01% | Add +2211.5% | 193,615 | $478K |
| Palumbo Wealth Management LLC | 0.14% | Add +92.1% | 183,358 | $453K |
| Alliancebernstein L.P. | 0.00% | Add +120.3% | 167,420 | $414K |
| Bank of New York Mellon Corp | 0.00% | Add +3.9% | 162,052 | $400K |
| Millennium Management | 0.00% | Reduce -91.7% | 147,996 | $366K |
| Bank of America Corp. | 0.00% | Add +28.0% | 144,511 | $357K |
| Levin Capital Strategies, L.P. | 0.03% | Add +300.0% | 140,000 | $346K |
| XTX Topco Ltd | 0.01% | New | 133,490 | $330K |
| Deutsche Bank AG | 0.00% | Reduce -1.1% | 125,445 | $310K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +253.4% | 119,856 | $296K |
| FIL Ltd | 0.00% | Reduce -3.1% | 117,270 | $290K |
| Barclays PLC | 0.00% | Add +60.7% | 114,802 | $284K |
| Diametric Capital, LP | 0.14% | New | 105,530 | $261K |
| Wells Fargo & Company | 0.00% | Add +11.4% | 101,151 | $250K |
| National Bank of Canada | 0.00% | New | 98,807 | $244K |
| Rhumbline Advisers | 0.00% | Add +19.6% | 97,972 | $242K |
| Green Alpha Advisors, LLC | 0.19% | Reduce -5.4% | 78,994 | $195K |
| Mutual Advisors, LLC | 0.00% | New | 45,200 | $190K |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -95.8% | 65,320 | $162K |
| HRT Financial LP | 0.00% | New | 64,167 | $158K |
| Prelude Capital Management, LLC | 0.01% | New | 41,288 | $102K |
| MetLife Investment Management, LLC | 0.00% | New | 39,014 | $96K |
| Jaffetilchin Investment Partners, LLC | 0.01% | New | 37,744 | $93K |
| Axq Capital, LP | 0.03% | New | 37,587 | $93K |
| Ieq Capital, LLC | 0.00% | Add +2.7% | 35,830 | $89K |
| Squarepoint Ops LLC | 0.00% | New | 35,826 | $88K |
| Cwm, LLC | 0.00% | Add +74.7% | 35,761 | $88K |
| Citigroup Inc. | 0.00% | Reduce -17.8% | 34,759 | $86K |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd | 0.01% | Reduce -62.5% | 33,660 | $83K |
| JPMorgan Chase & Co. | 0.00% | Reduce -7.4% | 33,035 | $82K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Add +112.7% | 26,007 | $81K |
| Crestwood Advisors Group, LLC | 0.00% | No change | 31,687 | $78K |
| Intech Investment Management LLC | 0.00% | Reduce -43.9% | 30,810 | $76K |
| SG Americas Securities, LLC | 0.00% | Reduce -45.7% | 27,919 | $69K |
| Jane Street Group, LLC | 0.00% | New | 27,145 | $67K |
| BNP Paribas Financial Markets | 0.00% | Reduce -14.6% | 26,735 | $66K |
| China Universal Asset Management Co., Ltd. | 0.01% | Add +0.2% | 26,370 | $65K |
| Kingsview Wealth Management, LLC | 0.00% | New | 25,000 | $62K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Add +52.2% | 23,191 | $57K |
| TD Asset Management Inc | 0.00% | Reduce -50.7% | 22,910 | $57K |
| HighTower Advisors, LLC | 0.00% | Reduce -1.4% | 21,354 | $53K |
| Federation des caisses Desjardins du Quebec | 0.00% | New | 21,200 | $52K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -15.8% | 20,979 | $52K |
| Voya Investment Management LLC | 0.00% | No change | 17,222 | $43K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 17,092 | $42K |
| ProShare Advisors LLC | 0.00% | Reduce -7.3% | 16,871 | $42K |
| Clarius Group, LLC | 0.00% | No change | 16,080 | $40K |
| Prime Capital Investment Advisors, LLC | 0.00% | Reduce -33.9% | 16,031 | $40K |
| Commonwealth Equity Services, LLC | 0.00% | New | 14,942 | $37K |
| Cibc World Market Inc. | 0.00% | Reduce -15.8% | 14,326 | $35K |
| Invesco Ltd. | 0.00% | Reduce -7.9% | 13,662 | $34K |
| JTC Employer Solutions Trustee Ltd | 0.00% | New | 13,249 | $33K |
| Virtu Financial LLC | 0.00% | New | 12,545 | $31K |
| R Squared Ltd | 0.02% | New | 12,519 | $31K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +23.6% | 12,246 | $30K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 11,420 | $28K |
| Freedom Investment Management, Inc. | 0.00% | New | 10,432 | $26K |
| Creative Planning | 0.00% | New | 10,145 | $25K |
| Fogel Capital Management, Inc. | 0.01% | New | 10,000 | $25K |
| New York State Common Retirement Fund | 0.00% | No change | 8,434 | $21K |
| Royal Bank of Canada | 0.00% | Add +213.7% | 5,145 | $13K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +15.6% | 5,072 | $13K |
| Legal & General Group Plc | 0.00% | Reduce -17.2% | 4,899 | $12K |
| Nisa Investment Advisors, LLC | 0.00% | Add +1244.8% | 4,236 | $10K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 3,901 | $10K |
| GF Fund Management Co. LTD. | 0.00% | No change | 3,358 | $8K |
| Amalgamated Bank | 0.00% | No change | 1,957 | $5K |
| Sterling Capital Management LLC | 0.00% | Add +2617.2% | 1,576 | $4K |
"% of holder's portfolio" is PRME's weight in each manager's 13F, not the share of Prime Medicine Inc. the manager owns.