Prothena Corp.PRTA

13F holders, Q2 2025 (June 30)
188holders +27
51new positions
22sold out
5famous investors
$6.07avg. 13F price*

At the end of Q2 2025, 188 institutions reported holding Prothena Corp. PLC (PRTA) in their 13F filings, up 27 from Q1 2025. 51 opened new positions and 22 sold out. The largest holders were FMR LLC ($48.0M), BlackRock, Inc. ($23.9M) and ADAR1 Capital Management, LLC ($20.5M). 5 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).

Company
Prothena Corp. PLC
CUSIP
G72800108
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150200 Q1 2024: 169Q1 2024Q2 2024: 160Q2 2024Q3 2024: 164Q3 2024Q4 2024: 170Q4 2024Q1 2025: 161Q1 2025Q2 2025: 188Q2 2025Q3 2025: 187Q3 2025Q4 2025: 182Q4 2025Q1 2026: 186Q1 2026Q2 2026: 187Q2 2026

Total Exit/New Position Q1 2025 → Q2 2025

InstitutionsTotal Value
New Positions51$59.5M
Exits22$177.8M

All 13F filers, Q1 2025 → Q2 2025: 15,030,657 shares bought and 25,576,487 shares sold, net −10,545,830 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 188 holders

FMR LLC 0.00% Reduce -0.5% 7,901,218 $48.0M
BlackRock, Inc. 0.00% Reduce -2.5% 3,939,398 $23.9M
ADAR1 Capital Management, LLC 3.36% New 3,375,009 $20.5M
Armistice Capital, LLC 0.51% Add +1.8% 2,236,000 $13.6M
Vanguard Group Inc. 0.00% Add +71.5% 2,176,227 $13.2M
Palo Alto Investors LP 1.65% Reduce -23.2% 1,274,753 $7.7M
Federated Hermes, Inc. 0.01% Add +116.2% 1,181,087 $7.2M
Citadel Advisors 0.01% Add +1183.7% 1,147,622 $7.0M
Acadian Asset Management LLC 0.01% New 1,018,177 $6.2M
State Street Corp. 0.00% Reduce -33.9% 1,005,002 $6.1M
Dimensional Fund Advisors LP 0.00% Add +11.5% 962,339 $5.8M
Morgan Stanley 0.00% Add +32.4% 953,256 $5.8M
Geode Capital Management, LLC 0.00% Reduce -8.0% 933,446 $5.7M
Rangeley Capital, LLC 5.65% New 715,367 $4.3M
Jacobs Levy Equity Management, Inc. 0.02% Add +3636.1% 693,154 $4.2M
Balyasny Asset Management L.P. 0.01% New 575,792 $3.5M
Trexquant Investment LP 0.04% New 552,826 $3.4M
Goldman Sachs Group Inc. 0.00% Add +3.5% 528,323 $3.2M
Cubist Systematic Strategies, LLC 0.03% New 501,764 $3.0M
Rock Springs Capital Management LP 0.19% No change 492,601 $3.0M
Granahan Investment Management, LLC 0.11% New 461,082 $2.8M
Birchview Capital, LP 2.72% Add +35.5% 451,019 $2.7M
Qube Research & Technologies Ltd 0.00% New 414,828 $2.5M
D. E. Shaw & Co. 0.00% Add +2099.0% 391,495 $2.4M
Mariner, LLC 0.00% Add +9.0% 386,708 $2.3M
Northern Trust Corp. 0.00% Reduce -10.5% 334,554 $2.0M
Nordea Investment Management AB 0.00% Add +1.2% 311,605 $1.9M
Schonfeld Strategic Advisors LLC 0.01% New 307,341 $1.9M
Charles Schwab Investment Management Inc. 0.00% Reduce -13.9% 275,084 $1.7M
Prosight Management, LP 0.40% Reduce -34.4% 267,800 $1.6M
Bank of America Corp. 0.00% Add +59.8% 210,945 $1.3M
Gsa Capital Partners LLP 0.09% New 210,555 $1.3M
Squarepoint Ops LLC 0.00% New 209,249 $1.3M
Monimus Capital Management, LP 1.01% New 206,475 $1.3M
Two Sigma Investments, LP 0.00% Add +1156.5% 201,450 $1.2M
Millennium Management 0.00% Add +225.1% 170,579 $1.0M
DCF Advisers, LLC 0.46% Reduce -19.7% 156,500 $950K
Ameriprise Financial Inc. 0.00% New 151,543 $920K
Bank of New York Mellon Corp 0.00% Add +1.6% 148,350 $900K
Two Sigma Advisers, LP 0.00% New 139,800 $849K
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% Reduce -63.5% 139,284 $845K
JPMorgan Chase & Co. 0.00% Reduce -65.9% 126,951 $771K
Nuveen, LLC 0.00% Reduce -18.5% 122,155 $741K
Jane Street Group, LLC 0.00% Reduce -11.4% 117,453 $713K
Barclays PLC 0.00% Add +38.9% 115,848 $703K
Wellington Management Group LLP 0.00% Reduce -97.9% 107,839 $655K
Royal Bank of Canada 0.00% Add +2353.4% 105,939 $643K
State of Wisconsin Investment Board 0.00% New 103,996 $631K
Russell Investments Group, Ltd. 0.00% Add +7956.6% 96,196 $584K
Susquehanna International Group, LLP 0.00% Add +19.0% 91,950 $558K
Renaissance Technologies 0.00% Reduce -62.4% 90,200 $548K
Duncan Williams Asset Management, LLC 0.17% No change 88,339 $536K
Alliancebernstein L.P. 0.00% Add +87.3% 87,587 $532K
Hennion & Walsh Asset Management, Inc. 0.02% Add +11.0% 86,154 $523K
Pinnacle Associates Ltd. 0.01% Reduce -26.1% 74,079 $450K
Susquehanna Portfolio Strategies, LLC 0.01% New 71,668 $435K
T. Rowe Price Associates Inc. 0.00% Reduce -97.9% 71,047 $432K
Monaco Asset Management SAM 0.16% New 70,000 $425K
Caption Management, LLC 0.04% New 65,100 $395K
Rhumbline Advisers 0.00% Reduce -4.7% 63,005 $382K
UBS Group AG 0.00% Reduce -75.2% 60,664 $368K
American Century Companies Inc. 0.00% Add +72.1% 59,965 $364K
Quantinno Capital Management LP 0.00% New 59,618 $362K
ExodusPoint Capital Management, LP 0.00% Add +42.8% 58,918 $358K
Norges Bank 0.00% No change 57,454 $349K
Swiss National Bank 0.00% Reduce -17.8% 56,500 $343K
Franklin Resources Inc. 0.00% Add +184.0% 56,078 $340K
SG Americas Securities, LLC 0.00% Reduce -28.4% 51,941 $315K
Creative Planning 0.00% Add +373.1% 50,569 $307K
Quinn Opportunity Partners LLC 0.03% New 50,000 $304K
Citigroup Inc. 0.00% Reduce -25.1% 49,303 $299K
Algert Global LLC 0.01% New 48,150 $292K
BNP Paribas Financial Markets 0.00% Add +389.1% 46,844 $284K
HSBC Holdings PLC 0.00% Add +251.8% 46,047 $282K
Massachusetts Financial Services Co. 0.00% Add +1.3% 44,364 $269K
Simplex Trading, LLC 0.01% New 43,264 $262K
Man Group plc 0.00% Add +151.5% 42,752 $260K
Covestor Ltd 0.15% Add +1057275.0% 42,295 $257K
Public Employees Retirement System of Ohio 0.00% New 42,158 $256K
PDT Partners, LLC 0.01% Reduce -72.5% 41,281 $251K
Wells Fargo & Company 0.00% Reduce -10.2% 41,220 $250K
Engineers Gate Manager LP 0.00% New 40,967 $249K
Deutsche Bank AG 0.00% Reduce -58.7% 39,601 $240K
Thrivent Financial for Lutherans 0.00% No change 38,626 $234K
Susquehanna Fundamental Investments, LLC 0.01% Reduce -49.7% 37,591 $228K
Invesco Ltd. 0.00% Reduce -2.0% 36,885 $224K
Graham Capital Management, L.P. 0.01% New 34,042 $207K
California State Teachers Retirement System 0.00% No change 33,243 $202K
Dark Forest Capital Management LP 0.01% Add +56.1% 32,866 $199K
Group One Trading LLC 0.01% New 32,258 $196K
Focused Wealth Management, Inc 0.02% No change 32,129 $195K
RBF Capital, LLC 0.01% No change 29,200 $177K
Alps Advisors Inc. 0.00% Reduce -23.5% 29,028 $176K
Tudor Investment Corporation 0.00% New 27,999 $170K
Cambridge Investment Research Advisors, Inc. 0.00% Add +168.7% 27,311 $166K
Sherbrooke Park Advisers LLC 0.07% New 27,221 $165K
MetLife Investment Management, LLC 0.00% No change 25,402 $154K
Purkiss Capital Advisors LLC 0.08% Add +15.1% 24,904 $151K
Edgewood Management LLC 0.00% No change 24,060 $146K
Point72 (DIFC) Ltd 0.01% New 23,946 $145K
Quadrature Capital Ltd 0.00% New 23,752 $144K
Nebula Research & Development LLC 0.01% New 22,857 $139K
Ensign Peak Advisors, Inc 0.00% No change 21,643 $131K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Reduce -22.4% 21,218 $129K
Handelsbanken Fonder AB 0.00% No change 20,900 $127K
Mogy Joel R Investment Counsel Inc. 0.01% New 20,750 $126K
Foundation Wealth Management, LLC 0.08% No change 19,471 $118K
Connor, Clark & Lunn Investment Management Ltd. 0.00% Reduce -79.3% 18,896 $115K
Oppenheimer & Co. Inc. 0.00% New 18,595 $113K
Virtus Investment Advisers, LLC 0.04% Add +56.0% 18,547 $113K
Voleon Capital Management LP 0.01% New 18,536 $113K
Intech Investment Management LLC 0.00% Reduce -45.0% 18,374 $112K
Jain Global LLC 0.00% New 18,262 $111K
Janus Henderson Group PLC 0.00% No change 18,047 $110K
PNC Financial Services Group, Inc. 0.00% Add +3594.3% 18,028 $109K
Los Angeles Capital Management LLC 0.00% New 16,702 $101K
Chicago Partners Investment Group LLC 0.00% Add +1.7% 14,759 $100K
STRS Ohio 0.00% New 16,400 $100K
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% Reduce -2.9% 15,568 $94K
State Board of Administration of Florida Retirement System 0.00% No change 15,386 $93K
Shelton Capital Management 0.00% Add +0.3% 15,279 $93K
Manufacturers Life Insurance Company, The 0.00% Reduce -76.8% 15,140 $92K
Jones Financial Companies LLLP 0.00% New 14,000 $85K
Corton Capital Inc. 0.10% New 13,964 $85K
DekaBank Deutsche Girozentrale 0.00% No change 14,000 $84K
Raymond James Financial Inc. 0.00% Add +8.1% 13,496 $82K
Tower Research Capital LLC (TRC) 0.00% Add +571.0% 12,709 $77K
Cary Street Partners Financial LLC 0.00% No change 12,500 $76K
Voya Investment Management LLC 0.00% Add +1.8% 11,896 $72K
Commonwealth Equity Services, LLC 0.00% Reduce -11.3% 11,820 $72K
Two Sigma Securities, LLC 0.01% New 11,683 $71K
Coastal Bridge Advisors, LLC 0.01% New 11,433 $69K
Brooklyn Investment Group 0.01% Add +533.6% 11,113 $67K
China Universal Asset Management Co., Ltd. 0.01% Add +0.1% 10,811 $66K
Police & Firemen's Retirement System of New Jersey 0.00% No change 10,113 $61K
Prospera Financial Services Inc 0.00% New 10,000 $61K
Legal & General Group Plc 0.00% Reduce -77.5% 9,323 $57K
US Bancorp \de 0.00% Add +1663.9% 9,031 $55K
New York State Common Retirement Fund 0.00% Reduce -37.1% 8,979 $55K
KLP Kapitalforvaltning As 0.00% No change 6,700 $41K
Public Employees Retirement Association of Colorado 0.00% No change 6,552 $40K
Brown Brothers Harriman & Co. 0.00% New 5,000 $30K
Ameritas Investment Partners, Inc. 0.00% No change 4,368 $27K
Signaturefd, LLC 0.00% Add +832.5% 3,357 $20K
Farther Finance Advisors, LLC 0.00% Add +154.1% 2,457 $15K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +15.4% 2,079 $13K
Walleye Capital LLC 0.00% New 2,058 $12K
Versant Capital Management, Inc 0.00% Add +284.9% 2,044 $12K
HighMark Wealth Management LLC 0.01% No change 2,018 $12K
Flagship Wealth Advisors, LLC 0.00% New 1,500 $9K
Amalgamated Bank 0.00% No change 1,440 $9K
GF Fund Management Co. LTD. 0.00% No change 1,377 $8K
Cwm, LLC 0.00% Add +115.1% 1,366 $8K
SBI Securities Co., Ltd. 0.00% No change 962 $6K
Sterling Capital Management LLC 0.00% Add +189.7% 959 $6K
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.00% New 683 $4K
HM Payson & Co. 0.00% No change 600 $4K
Parallel Advisors, LLC 0.00% Add +747.1% 593 $4K
Nisa Investment Advisors, LLC 0.00% Reduce -57.5% 526 $3K
Point72 Asia (Singapore) Pte. Ltd. 0.00% New 459 $3K
Allworth Financial LP 0.00% Add +691.5% 372 $2K
Huntington National Bank 0.00% New 324 $2K
Manchester Capital Management LLC 0.00% No change 250 $2K
Osaic Holdings, Inc. 0.00% Add +53.4% 247 $1K
Spire Wealth Management 0.00% No change 200 $1K
Evelyn Partners Investment Management LLP 0.00% No change 199 $1K
GAMMA Investing LLC 0.00% Reduce -59.4% 197 $1K
Asset Dedication, LLC 0.00% No change 184 $1K
Daiwa Securities Group Inc. 0.00% No change 195 $1K
North Capital, Inc. 0.00% No change 159 $965
Sittner & Nelson, LLC 0.00% No change 155 $941
MAI Capital Management 0.00% New 155 $941
Albion Financial Group 0.00% No change 125 $759
Gould Capital, LLC 0.00% No change 100 $607
Harbor Investment Advisory, LLC 0.00% No change 100 $607
CVA Family Office, LLC 0.00% No change 72 $437
Truvestments Capital LLC 0.00% Add +1.5% 69 $418
CIBC Private Wealth Group LLC 0.00% No change 49 $297
Blue Trust, Inc. 0.00% Reduce -95.4% 33 $200
CoreCap Advisors, LLC 0.00% No change 23 $140
Key Financial Inc 0.00% No change 12 $73
Lowe Wealth Advisors, LLC 0.00% No change 10 $61
Steward Partners Investment Advisory, LLC 0.00% New 6 $36
Clearstead Advisors, LLC 0.00% No change 4 $25
Whittier Trust Co. of Nevada Inc. 0.00% No change 3 $18
CBIZ Investment Advisory Services, LLC 0.00% No change 2 $12
Koesten, Hirschmann & Crabtree, INC. 0.00% New 1 $9
Harbour Investments, Inc. 0.00% Reduce -66.7% 1 $6

"% of holder's portfolio" is PRTA's weight in each manager's 13F, not the share of Prothena Corp. PLC the manager owns.