Summit TherapeuticsSMMT
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 206 institutions reported holding Summit Therapeutics Inc. (SMMT) in their 13F filings, down 26 from Q3 2025. 27 opened new positions and 59 sold out. The largest holders were Baker Bros. Advisors LP ($636.5M), FMR LLC ($233.7M) and Vanguard Group Inc. ($195.5M). 6 famous investors held it, including Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Summit Therapeutics Inc.
- CUSIP
- 86627T108
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 27 | $14.0M |
| Exits | 59 | $76.4M |
All 13F filers, Q3 2025 → Q4 2025: 21,398,654 shares bought and 7,926,984 shares sold, net +13,471,670 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 206 holders
| Baker Bros. Advisors LP | 3.74% | Add +7.9% | 36,391,063 | $636.5M |
| FMR LLC | 0.01% | Add +49.8% | 13,360,807 | $233.7M |
| Vanguard Group Inc. | 0.00% | Reduce -1.8% | 11,177,220 | $195.5M |
| T. Rowe Price Associates Inc. | 0.02% | Add +106.5% | 9,371,415 | $163.9M |
| BlackRock, Inc. | 0.00% | Add +27.1% | 9,361,921 | $163.7M |
| State Street Corp. | 0.00% | Add +4.3% | 6,636,361 | $116.1M |
| Geode Capital Management, LLC | 0.00% | Add +0.5% | 3,147,480 | $55.1M |
| Citadel Advisors | 0.03% | Add +1121.3% | 2,475,708 | $43.3M |
| Polymer Capital Management (HK) LTD | 3.87% | Add +73.9% | 1,421,155 | $24.9M |
| Pictet Asset Management Holding SA | 0.02% | Reduce -13.7% | 1,383,775 | $24.4M |
| Norges Bank | 0.00% | — | 1,373,943 | $24.0M |
| APEIRON CAPITAL Ltd | 26.48% | Reduce -0.1% | 1,309,241 | $22.9M |
| TD Asset Management Inc | 0.02% | Add +124.2% | 1,205,272 | $21.1M |
| Aberdeen Group plc | 0.03% | Reduce -18.6% | 927,171 | $16.2M |
| Morgan Stanley | 0.00% | Reduce -51.9% | 926,579 | $16.2M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +1.9% | 892,629 | $15.6M |
| UBS Group AG | 0.00% | Reduce -31.9% | 870,719 | $15.2M |
| Squarepoint Ops LLC | 0.03% | Add +551.4% | 715,410 | $12.5M |
| Rock Springs Capital Management LP | 0.64% | No change | 710,000 | $12.4M |
| Two Sigma Investments, LP | 0.02% | Add +2210.2% | 578,248 | $10.1M |
| Nomura Holdings Inc. | 0.03% | Reduce -48.3% | 542,234 | $9.5M |
| Candriam S.C.A. | 0.05% | Add +5.2% | 540,662 | $9.5M |
| Northern Trust Corp. | 0.00% | Reduce -3.3% | 528,487 | $9.2M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -2.4% | 485,566 | $8.5M |
| Bank of America Corp. | 0.00% | Reduce -27.4% | 477,393 | $8.3M |
| Millennium Management | 0.01% | Add +289.2% | 469,017 | $8.2M |
| Invesco Ltd. | 0.00% | Add +8.3% | 461,301 | $8.1M |
| Manufacturers Life Insurance Company, The | 0.01% | Add +47.2% | 440,953 | $7.7M |
| Tudor Investment Corporation | 0.04% | Add +21.8% | 423,084 | $7.4M |
| D. E. Shaw & Co. | 0.01% | Add +217.9% | 415,284 | $7.3M |
| Dimensional Fund Advisors LP | 0.00% | Add +0.5% | 376,563 | $6.6M |
| QVT Financial LP | 0.61% | No change | 360,524 | $6.3M |
| Sculptor Capital LP | 0.13% | Add +7.0% | 356,900 | $6.2M |
| AQR Capital Management | 0.00% | Add +90.9% | 357,870 | $6.2M |
| Bank of New York Mellon Corp | 0.00% | Reduce -3.6% | 353,756 | $6.2M |
| Barclays PLC | 0.00% | Reduce -28.9% | 338,390 | $5.9M |
| Skandinaviska Enskilda Banken AB (publ) | 0.02% | No change | 338,363 | $5.9M |
| Readystate Asset Management LP | 0.41% | New | 306,184 | $5.4M |
| Rafferty Asset Management, LLC | 0.02% | Reduce -15.1% | 287,810 | $5.0M |
| Schroder Investment Management Group | 0.00% | Add +3.6% | 251,391 | $4.4M |
| Deutsche Bank AG | 0.00% | Reduce -11.9% | 237,788 | $4.2M |
| Nuveen, LLC | 0.00% | No change | 232,642 | $4.1M |
| Verition Fund Management LLC | 0.02% | Add +38.3% | 228,990 | $4.0M |
| Woodline Partners LP | 0.01% | No change | 214,507 | $3.8M |
| Griffin Asset Management, Inc. | 0.37% | Add +39.4% | 195,547 | $3.4M |
| Wells Fargo & Company | 0.00% | Reduce -32.1% | 130,886 | $2.3M |
| Citigroup Inc. | 0.00% | Reduce -18.7% | 129,926 | $2.3M |
| Rhumbline Advisers | 0.00% | Reduce -1.3% | 121,341 | $2.1M |
| China Universal Asset Management Co., Ltd. | 0.16% | Reduce -6.8% | 121,307 | $2.1M |
| Capital Fund Management S.A. | 0.02% | Add +52.9% | 113,391 | $2.0M |
| Cerity Partners LLC | 0.00% | Reduce -1.6% | 112,878 | $2.0M |
| Voya Investment Management LLC | 0.00% | Reduce -44.5% | 112,437 | $2.0M |
| Profund Advisors LLC | 0.06% | Add +48.4% | 103,761 | $1.8M |
| Jefferies Financial Group Inc. | 0.01% | Add +566.7% | 100,000 | $1.7M |
| Illinois Municipal Retirement Fund | 0.02% | Add +44.7% | 99,367 | $1.7M |
| HSBC Holdings PLC | 0.00% | New | 98,766 | $1.7M |
| NEOS Investment Management LLC | 0.01% | Add +21.1% | 97,217 | $1.7M |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 96,009 | $1.7M |
| Tema ETFs LLC | 0.13% | Add +19.3% | 95,782 | $1.7M |
| Bank of Montreal | 0.00% | Reduce -2.7% | 95,371 | $1.7M |
| State of Wisconsin Investment Board | 0.00% | Add +1.1% | 92,882 | $1.6M |
| ADAR1 Capital Management, LLC | 0.12% | Reduce -10.8% | 91,869 | $1.6M |
| Focus Partners Wealth | 0.00% | Add +0.0% | 88,448 | $1.5M |
| Dark Forest Capital Management LP | 0.07% | Reduce -22.4% | 87,069 | $1.5M |
| Axq Capital, LP | 0.32% | Add +366.7% | 81,519 | $1.4M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +0.1% | 79,626 | $1.4M |
| Sectoral Asset Management Inc. | 1.12% | Add +7.5% | 79,625 | $1.4M |
| LMR Partners LLP | 0.02% | New | 75,200 | $1.3M |
| Polianta Ltd | 0.17% | No change | 74,700 | $1.3M |
| Mariner, LLC | 0.00% | Reduce -7.6% | 73,497 | $1.3M |
| JPMorgan Chase & Co. | 0.00% | Reduce -50.6% | 67,422 | $1.2M |
| DNB Asset Management AS | 0.00% | Add +97.5% | 61,061 | $1.1M |
| Aquatic Capital Management LLC | 0.03% | New | 59,945 | $1.0M |
| Assenagon Asset Management S.A. | 0.00% | New | 59,621 | $1.0M |
| Wealth Management Partners, LLC | 0.30% | Reduce -20.3% | 59,430 | $1.0M |
| Farther Finance Advisors, LLC | 0.01% | Add +3.7% | 57,282 | $1.0M |
| Ameriprise Financial Inc. | 0.00% | Add +0.9% | 54,012 | $945K |
| New York State Common Retirement Fund | 0.00% | Reduce -79.7% | 53,777 | $941K |
| Police & Firemen's Retirement System of New Jersey | 0.01% | Add +0.2% | 52,619 | $920K |
| Balyasny Asset Management L.P. | 0.00% | Reduce -74.2% | 50,298 | $880K |
| Guggenheim Capital LLC | 0.01% | Add +21.5% | 49,798 | $871K |
| Treasurer of the State of North Carolina | 0.00% | Reduce -6.8% | 48,940 | $856K |
| Worldquant Millennium Advisors LLC | 0.00% | New | 41,734 | $730K |
| Beacon Pointe Advisors, LLC | 0.00% | Add +10.9% | 39,611 | $693K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +24.2% | 37,991 | $664K |
| Levin Capital Strategies, L.P. | 0.06% | Add +2.7% | 37,676 | $659K |
| Handelsbanken Fonder AB | 0.00% | Add +9.9% | 37,600 | $658K |
| BNP Paribas Financial Markets | 0.00% | Add +27.1% | 37,084 | $649K |
| Vident Advisory, LLC | 0.01% | Reduce -2.1% | 35,880 | $628K |
| Public Employees Retirement System of Ohio | 0.00% | Reduce -3.7% | 35,158 | $615K |
| ProShare Advisors LLC | 0.00% | Add +24.3% | 32,881 | $575K |
| Group One Trading LLC | 0.02% | Add +3.8% | 31,410 | $549K |
| IMC-Chicago, LLC | 0.01% | New | 29,704 | $520K |
| Capstone Capital Management Ltd | 0.47% | — | 28,190 | $493K |
| First Trust Advisors LP | 0.00% | Reduce -83.6% | 28,115 | $492K |
| Legal & General Group Plc | 0.00% | Add +3.1% | 27,359 | $479K |
| Schonfeld Strategic Advisors LLC | 0.00% | New | 27,304 | $478K |
| Eurizon Capital SGR S.p.A. | 0.00% | — | 25,662 | $449K |
| Great Valley Advisor Group, Inc. | 0.01% | Reduce -0.1% | 25,640 | $448K |
| Entropy Technologies, LP | 0.02% | New | 25,162 | $440K |
| CIBC Asset Management Inc | 0.00% | Add +9.8% | 24,289 | $425K |
| Steward Partners Investment Advisory, LLC | 0.00% | Add +15.7% | 23,045 | $403K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Add +27.2% | 20,875 | $390K |
| Allianz Asset Management GmbH | 0.00% | No change | 22,200 | $388K |
| Cynosure Group, LLC | 0.04% | Add +18.6% | 22,070 | $386K |
| Alliancebernstein L.P. | 0.00% | Add +1.9% | 20,606 | $360K |
| Vance Wealth, LLC | 0.10% | Add +0.4% | 19,983 | $350K |
| Q3 Asset Management | 0.08% | No change | 19,567 | $342K |
| Raymond James Financial Inc. | 0.00% | Add +26.5% | 17,851 | $312K |
| Xponance LLC | 0.00% | Add +2.7% | 17,503 | $306K |
| Russell Investments Group, Ltd. | 0.00% | Reduce -70.8% | 16,966 | $297K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -6.3% | 16,860 | $295K |
| Qsemble Capital Management, LP | 0.02% | Reduce -5.1% | 16,419 | $287K |
| Gotham Asset Management | 0.00% | No change | 15,727 | $275K |
| SG Americas Securities, LLC | 0.00% | Add +204.7% | 15,589 | $273K |
| Campbell & CO Investment Adviser LLC | 0.01% | New | 15,407 | $269K |
| Virtus Investment Advisers, LLC | 0.07% | Add +168.3% | 15,141 | $265K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -8.5% | 14,629 | $256K |
| Quantinno Capital Management LP | 0.00% | New | 14,323 | $251K |
| Bellevue Group AG | 0.00% | Reduce -24.9% | 14,262 | $249K |
| LPL Financial LLC | 0.00% | Reduce -42.3% | 13,160 | $230K |
| Three Seasons Wealth, LLC | 0.02% | No change | 12,869 | $225K |
| Creative Planning | 0.00% | Reduce -17.3% | 12,811 | $224K |
| Blankinship & Foster, LLC | 0.05% | No change | 12,777 | $223K |
| U.S. Capital Wealth Advisors, LLC | 0.01% | No change | 12,000 | $210K |
| Machina Capital S.A.S. | 0.04% | New | 11,636 | $204K |
| State of Wyoming | 0.02% | New | 11,533 | $202K |
| Hudson Bay Capital Management LP | 0.00% | New | 11,440 | $200K |
| Advisors Asset Management, Inc. | 0.00% | Reduce -0.0% | 11,125 | $195K |
| Evoke Wealth, LLC | 0.00% | Reduce -17.5% | 11,052 | $193K |
| Two Sigma Advisers, LP | 0.00% | New | 10,700 | $187K |
| Willis Investment Counsel | 0.01% | Add +3.9% | 10,390 | $182K |
| Sei Investments Co. | 0.00% | Reduce -63.0% | 10,063 | $176K |
| Sargent Investment Group, LLC | 0.02% | No change | 10,000 | $175K |
| Amalgamated Bank | 0.00% | Add +10.7% | 9,465 | $166K |
| Federation des caisses Desjardins du Quebec | 0.00% | Reduce -7.4% | 8,613 | $151K |
| MetLife Investment Management, LLC | 0.00% | Add +0.9% | 7,544 | $132K |
| California State Teachers Retirement System | 0.00% | Reduce -1.4% | 7,270 | $127K |
| Havemeyer Place LP | 0.02% | — | 6,254 | $109K |
| AlphaQuest LLC | 0.01% | Reduce -67.9% | 6,188 | $108K |
| Osaic Holdings, Inc. | 0.00% | Reduce -3.9% | 5,281 | $92K |
| Osterweis Capital Management Inc. | 0.01% | No change | 5,000 | $87K |
| IFP Advisors, Inc | 0.00% | No change | 4,429 | $77K |
| Royal Bank of Canada | 0.00% | Reduce -98.3% | 3,196 | $56K |
| Fifth Third Bancorp | 0.00% | No change | 3,000 | $52K |
| STRS Ohio | 0.00% | Add +0.2% | 2,798 | $49K |
| Truvestments Capital LLC | 0.01% | Add +200.2% | 2,603 | $46K |
| Adirondack Trust Co. | 0.01% | No change | 2,500 | $44K |
| Daiwa Securities Group Inc. | 0.00% | Reduce -83.0% | 2,157 | $38K |
| T. Rowe Price Investment Management, Inc. | 0.00% | Add +2654.4% | 1,873 | $33K |
| Larson Financial Group LLC | 0.00% | Add +6.3% | 1,823 | $32K |
| National Bank of Canada | 0.00% | Add +121.9% | 1,695 | $30K |
| Kestra Advisory Services, LLC | 0.00% | New | 1,622 | $28K |
| Sound Income Strategies, LLC | 0.00% | No change | 1,005 | $17K |
| Bessemer Group Inc. | 0.00% | Add +651.9% | 1,015 | $17K |
| Sterling Capital Management LLC | 0.00% | Add +372.3% | 836 | $15K |
| Golden State Wealth Management, LLC | 0.00% | No change | 828 | $14K |
| GAMMA Investing LLC | 0.00% | Reduce -17.7% | 805 | $14K |
| Covestor Ltd | 0.01% | No change | 658 | $12K |
| Smartleaf Asset Management LLC | 0.00% | Add +11.2% | 635 | $11K |
| Jones Financial Companies LLLP | 0.00% | Add +26.3% | 548 | $10K |
| Vermillion Wealth Management, Inc. | 0.00% | No change | 504 | $9K |
| Rosenberg Matthew Hamilton | 0.00% | No change | 501 | $9K |
| PNC Financial Services Group, Inc. | 0.00% | Reduce -72.7% | 489 | $9K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | No change | 424 | $7K |
| US Bancorp \de | 0.00% | Reduce -52.3% | 325 | $6K |
| SBI Securities Co., Ltd. | 0.00% | Add +38.9% | 289 | $5K |
| WPG Advisers, LLC | 0.00% | New | 288 | $5K |
| Cwm, LLC | 0.00% | Add +139.8% | 295 | $5K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -21.3% | 237 | $4K |
| AdvisorNet Financial, Inc | 0.00% | New | 228 | $4K |
| Gunpowder Capital Management, LLC dba Oliver Wealth Management | 0.00% | — | 200 | $3K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +40.4% | 139 | $2K |
| Arax Advisory Partners | 0.00% | Reduce -11.3% | 94 | $2K |
| Toth Financial Advisory Corp. | 0.00% | New | 90 | $2K |
| J.Safra Asset Management Corp | 0.00% | No change | 83 | $1K |
| Signaturefd, LLC | 0.00% | Reduce -48.7% | 78 | $1K |
| TD Private Client Wealth LLC | 0.00% | No change | 74 | $1K |
| Allworth Financial LP | 0.00% | Reduce -80.7% | 69 | $1K |
| Harbour Investments, Inc. | 0.00% | Reduce -83.3% | 57 | $997 |
| Physician Wealth Advisors, Inc. | 0.00% | No change | 55 | $962 |
| Litman Gregory Wealth Management LLC | 0.00% | New | 50 | $875 |
| Parallel Advisors, LLC | 0.00% | Reduce -97.3% | 50 | $875 |
| Assetmark, Inc. | 0.00% | Reduce -99.8% | 44 | $770 |
| CVA Family Office, LLC | 0.00% | No change | 40 | $700 |
| ORG Partners LLC | 0.00% | No change | 40 | $699 |
| Comerica Bank | 0.00% | Reduce -95.8% | 32 | $560 |
| Rialto Wealth Management, LLC | 0.00% | New | 29 | $508 |
| Marquette Asset Management, LLC | 0.00% | New | 28 | $490 |
| United Financial Planning Group LLC | 0.00% | New | 20 | $350 |
| JFS Wealth Advisors, LLC | 0.00% | Reduce -62.9% | 13 | $228 |
| Versant Capital Management, Inc | 0.00% | New | 10 | $175 |
| SHP Wealth Management | 0.00% | — | 10 | $175 |
| Hughes Financial Services, LLC | 0.00% | New | 7 | $122 |
| Transamerica Financial Advisors, LLC | 0.00% | Add +50.0% | 6 | $105 |
| Stone House Investment Management, LLC | 0.00% | New | 6 | $105 |
| True Wealth Design, LLC | 0.00% | Reduce -14.3% | 6 | $105 |
| Rakuten Securities, Inc. | 0.00% | No change | 5 | $87 |
| CIBC Private Wealth Group LLC | 0.00% | New | 3 | $52 |
| Rothschild Investment LLC | 0.00% | Add +100.0% | 2 | $35 |
| Root Financial Partners, LLC | 0.00% | Reduce -94.4% | 2 | $35 |
| Seneschal Advisors, LLC | 0.00% | No change | 2 | $35 |
| Bay Harbor Wealth Management, LLC | 0.00% | Reduce -66.7% | 2 | $34 |
| SJS Investment Consulting Inc. | 0.00% | Reduce -85.7% | 1 | $18 |
| Keating Financial Advisory Services, Inc. | 0.00% | — | 1 | $17 |
| 1015 Capital Partners, LLC | 0.00% | — | 1 | $17 |
"% of holder's portfolio" is SMMT's weight in each manager's 13F, not the share of Summit Therapeutics Inc. the manager owns.