Summit TherapeuticsSMMT

13F holders, Q4 2025 (December 31)
206holders −26
27new positions
59sold out
6famous investors
$17.49avg. 13F price*

At the end of Q4 2025, 206 institutions reported holding Summit Therapeutics Inc. (SMMT) in their 13F filings, down 26 from Q3 2025. 27 opened new positions and 59 sold out. The largest holders were Baker Bros. Advisors LP ($636.5M), FMR LLC ($233.7M) and Vanguard Group Inc. ($195.5M). 6 famous investors held it, including Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).

Company
Summit Therapeutics Inc.
CUSIP
86627T108
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150200250 Q1 2024: 103Q1 2024Q2 2024: 121Q2 2024Q3 2024: 164Q3 2024Q4 2024: 196Q4 2024Q1 2025: 202Q1 2025Q2 2025: 226Q2 2025Q3 2025: 232Q3 2025Q4 2025: 206Q4 2025Q1 2026: 222Q1 2026Q2 2026: 242Q2 2026

Total Exit/New Position Q3 2025 → Q4 2025

InstitutionsTotal Value
New Positions27$14.0M
Exits59$76.4M

All 13F filers, Q3 2025 → Q4 2025: 21,398,654 shares bought and 7,926,984 shares sold, net +13,471,670 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 206 holders

Baker Bros. Advisors LP 3.74% Add +7.9% 36,391,063 $636.5M
FMR LLC 0.01% Add +49.8% 13,360,807 $233.7M
Vanguard Group Inc. 0.00% Reduce -1.8% 11,177,220 $195.5M
T. Rowe Price Associates Inc. 0.02% Add +106.5% 9,371,415 $163.9M
BlackRock, Inc. 0.00% Add +27.1% 9,361,921 $163.7M
State Street Corp. 0.00% Add +4.3% 6,636,361 $116.1M
Geode Capital Management, LLC 0.00% Add +0.5% 3,147,480 $55.1M
Citadel Advisors 0.03% Add +1121.3% 2,475,708 $43.3M
Polymer Capital Management (HK) LTD 3.87% Add +73.9% 1,421,155 $24.9M
Pictet Asset Management Holding SA 0.02% Reduce -13.7% 1,383,775 $24.4M
Norges Bank 0.00% — 1,373,943 $24.0M
APEIRON CAPITAL Ltd 26.48% Reduce -0.1% 1,309,241 $22.9M
TD Asset Management Inc 0.02% Add +124.2% 1,205,272 $21.1M
Aberdeen Group plc 0.03% Reduce -18.6% 927,171 $16.2M
Morgan Stanley 0.00% Reduce -51.9% 926,579 $16.2M
Charles Schwab Investment Management Inc. 0.00% Add +1.9% 892,629 $15.6M
UBS Group AG 0.00% Reduce -31.9% 870,719 $15.2M
Squarepoint Ops LLC 0.03% Add +551.4% 715,410 $12.5M
Rock Springs Capital Management LP 0.64% No change 710,000 $12.4M
Two Sigma Investments, LP 0.02% Add +2210.2% 578,248 $10.1M
Nomura Holdings Inc. 0.03% Reduce -48.3% 542,234 $9.5M
Candriam S.C.A. 0.05% Add +5.2% 540,662 $9.5M
Northern Trust Corp. 0.00% Reduce -3.3% 528,487 $9.2M
Goldman Sachs Group Inc. 0.00% Reduce -2.4% 485,566 $8.5M
Bank of America Corp. 0.00% Reduce -27.4% 477,393 $8.3M
Millennium Management 0.01% Add +289.2% 469,017 $8.2M
Invesco Ltd. 0.00% Add +8.3% 461,301 $8.1M
Manufacturers Life Insurance Company, The 0.01% Add +47.2% 440,953 $7.7M
Tudor Investment Corporation 0.04% Add +21.8% 423,084 $7.4M
D. E. Shaw & Co. 0.01% Add +217.9% 415,284 $7.3M
Dimensional Fund Advisors LP 0.00% Add +0.5% 376,563 $6.6M
QVT Financial LP 0.61% No change 360,524 $6.3M
Sculptor Capital LP 0.13% Add +7.0% 356,900 $6.2M
AQR Capital Management 0.00% Add +90.9% 357,870 $6.2M
Bank of New York Mellon Corp 0.00% Reduce -3.6% 353,756 $6.2M
Barclays PLC 0.00% Reduce -28.9% 338,390 $5.9M
Skandinaviska Enskilda Banken AB (publ) 0.02% No change 338,363 $5.9M
Readystate Asset Management LP 0.41% New 306,184 $5.4M
Rafferty Asset Management, LLC 0.02% Reduce -15.1% 287,810 $5.0M
Schroder Investment Management Group 0.00% Add +3.6% 251,391 $4.4M
Deutsche Bank AG 0.00% Reduce -11.9% 237,788 $4.2M
Nuveen, LLC 0.00% No change 232,642 $4.1M
Verition Fund Management LLC 0.02% Add +38.3% 228,990 $4.0M
Woodline Partners LP 0.01% No change 214,507 $3.8M
Griffin Asset Management, Inc. 0.37% Add +39.4% 195,547 $3.4M
Wells Fargo & Company 0.00% Reduce -32.1% 130,886 $2.3M
Citigroup Inc. 0.00% Reduce -18.7% 129,926 $2.3M
Rhumbline Advisers 0.00% Reduce -1.3% 121,341 $2.1M
China Universal Asset Management Co., Ltd. 0.16% Reduce -6.8% 121,307 $2.1M
Capital Fund Management S.A. 0.02% Add +52.9% 113,391 $2.0M
Cerity Partners LLC 0.00% Reduce -1.6% 112,878 $2.0M
Voya Investment Management LLC 0.00% Reduce -44.5% 112,437 $2.0M
Profund Advisors LLC 0.06% Add +48.4% 103,761 $1.8M
Jefferies Financial Group Inc. 0.01% Add +566.7% 100,000 $1.7M
Illinois Municipal Retirement Fund 0.02% Add +44.7% 99,367 $1.7M
HSBC Holdings PLC 0.00% New 98,766 $1.7M
NEOS Investment Management LLC 0.01% Add +21.1% 97,217 $1.7M
State Board of Administration of Florida Retirement System 0.00% No change 96,009 $1.7M
Tema ETFs LLC 0.13% Add +19.3% 95,782 $1.7M
Bank of Montreal 0.00% Reduce -2.7% 95,371 $1.7M
State of Wisconsin Investment Board 0.00% Add +1.1% 92,882 $1.6M
ADAR1 Capital Management, LLC 0.12% Reduce -10.8% 91,869 $1.6M
Focus Partners Wealth 0.00% Add +0.0% 88,448 $1.5M
Dark Forest Capital Management LP 0.07% Reduce -22.4% 87,069 $1.5M
Axq Capital, LP 0.32% Add +366.7% 81,519 $1.4M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% Add +0.1% 79,626 $1.4M
Sectoral Asset Management Inc. 1.12% Add +7.5% 79,625 $1.4M
LMR Partners LLP 0.02% New 75,200 $1.3M
Polianta Ltd 0.17% No change 74,700 $1.3M
Mariner, LLC 0.00% Reduce -7.6% 73,497 $1.3M
JPMorgan Chase & Co. 0.00% Reduce -50.6% 67,422 $1.2M
DNB Asset Management AS 0.00% Add +97.5% 61,061 $1.1M
Aquatic Capital Management LLC 0.03% New 59,945 $1.0M
Assenagon Asset Management S.A. 0.00% New 59,621 $1.0M
Wealth Management Partners, LLC 0.30% Reduce -20.3% 59,430 $1.0M
Farther Finance Advisors, LLC 0.01% Add +3.7% 57,282 $1.0M
Ameriprise Financial Inc. 0.00% Add +0.9% 54,012 $945K
New York State Common Retirement Fund 0.00% Reduce -79.7% 53,777 $941K
Police & Firemen's Retirement System of New Jersey 0.01% Add +0.2% 52,619 $920K
Balyasny Asset Management L.P. 0.00% Reduce -74.2% 50,298 $880K
Guggenheim Capital LLC 0.01% Add +21.5% 49,798 $871K
Treasurer of the State of North Carolina 0.00% Reduce -6.8% 48,940 $856K
Worldquant Millennium Advisors LLC 0.00% New 41,734 $730K
Beacon Pointe Advisors, LLC 0.00% Add +10.9% 39,611 $693K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +24.2% 37,991 $664K
Levin Capital Strategies, L.P. 0.06% Add +2.7% 37,676 $659K
Handelsbanken Fonder AB 0.00% Add +9.9% 37,600 $658K
BNP Paribas Financial Markets 0.00% Add +27.1% 37,084 $649K
Vident Advisory, LLC 0.01% Reduce -2.1% 35,880 $628K
Public Employees Retirement System of Ohio 0.00% Reduce -3.7% 35,158 $615K
ProShare Advisors LLC 0.00% Add +24.3% 32,881 $575K
Group One Trading LLC 0.02% Add +3.8% 31,410 $549K
IMC-Chicago, LLC 0.01% New 29,704 $520K
Capstone Capital Management Ltd 0.47% — 28,190 $493K
First Trust Advisors LP 0.00% Reduce -83.6% 28,115 $492K
Legal & General Group Plc 0.00% Add +3.1% 27,359 $479K
Schonfeld Strategic Advisors LLC 0.00% New 27,304 $478K
Eurizon Capital SGR S.p.A. 0.00% — 25,662 $449K
Great Valley Advisor Group, Inc. 0.01% Reduce -0.1% 25,640 $448K
Entropy Technologies, LP 0.02% New 25,162 $440K
CIBC Asset Management Inc 0.00% Add +9.8% 24,289 $425K
Steward Partners Investment Advisory, LLC 0.00% Add +15.7% 23,045 $403K
Wealth Enhancement Advisory Services, LLC 0.00% Add +27.2% 20,875 $390K
Allianz Asset Management GmbH 0.00% No change 22,200 $388K
Cynosure Group, LLC 0.04% Add +18.6% 22,070 $386K
Alliancebernstein L.P. 0.00% Add +1.9% 20,606 $360K
Vance Wealth, LLC 0.10% Add +0.4% 19,983 $350K
Q3 Asset Management 0.08% No change 19,567 $342K
Raymond James Financial Inc. 0.00% Add +26.5% 17,851 $312K
Xponance LLC 0.00% Add +2.7% 17,503 $306K
Russell Investments Group, Ltd. 0.00% Reduce -70.8% 16,966 $297K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Reduce -6.3% 16,860 $295K
Qsemble Capital Management, LP 0.02% Reduce -5.1% 16,419 $287K
Gotham Asset Management 0.00% No change 15,727 $275K
SG Americas Securities, LLC 0.00% Add +204.7% 15,589 $273K
Campbell & CO Investment Adviser LLC 0.01% New 15,407 $269K
Virtus Investment Advisers, LLC 0.07% Add +168.3% 15,141 $265K
GF Fund Management Co. LTD. 0.00% Reduce -8.5% 14,629 $256K
Quantinno Capital Management LP 0.00% New 14,323 $251K
Bellevue Group AG 0.00% Reduce -24.9% 14,262 $249K
LPL Financial LLC 0.00% Reduce -42.3% 13,160 $230K
Three Seasons Wealth, LLC 0.02% No change 12,869 $225K
Creative Planning 0.00% Reduce -17.3% 12,811 $224K
Blankinship & Foster, LLC 0.05% No change 12,777 $223K
U.S. Capital Wealth Advisors, LLC 0.01% No change 12,000 $210K
Machina Capital S.A.S. 0.04% New 11,636 $204K
State of Wyoming 0.02% New 11,533 $202K
Hudson Bay Capital Management LP 0.00% New 11,440 $200K
Advisors Asset Management, Inc. 0.00% Reduce -0.0% 11,125 $195K
Evoke Wealth, LLC 0.00% Reduce -17.5% 11,052 $193K
Two Sigma Advisers, LP 0.00% New 10,700 $187K
Willis Investment Counsel 0.01% Add +3.9% 10,390 $182K
Sei Investments Co. 0.00% Reduce -63.0% 10,063 $176K
Sargent Investment Group, LLC 0.02% No change 10,000 $175K
Amalgamated Bank 0.00% Add +10.7% 9,465 $166K
Federation des caisses Desjardins du Quebec 0.00% Reduce -7.4% 8,613 $151K
MetLife Investment Management, LLC 0.00% Add +0.9% 7,544 $132K
California State Teachers Retirement System 0.00% Reduce -1.4% 7,270 $127K
Havemeyer Place LP 0.02% — 6,254 $109K
AlphaQuest LLC 0.01% Reduce -67.9% 6,188 $108K
Osaic Holdings, Inc. 0.00% Reduce -3.9% 5,281 $92K
Osterweis Capital Management Inc. 0.01% No change 5,000 $87K
IFP Advisors, Inc 0.00% No change 4,429 $77K
Royal Bank of Canada 0.00% Reduce -98.3% 3,196 $56K
Fifth Third Bancorp 0.00% No change 3,000 $52K
STRS Ohio 0.00% Add +0.2% 2,798 $49K
Truvestments Capital LLC 0.01% Add +200.2% 2,603 $46K
Adirondack Trust Co. 0.01% No change 2,500 $44K
Daiwa Securities Group Inc. 0.00% Reduce -83.0% 2,157 $38K
T. Rowe Price Investment Management, Inc. 0.00% Add +2654.4% 1,873 $33K
Larson Financial Group LLC 0.00% Add +6.3% 1,823 $32K
National Bank of Canada 0.00% Add +121.9% 1,695 $30K
Kestra Advisory Services, LLC 0.00% New 1,622 $28K
Sound Income Strategies, LLC 0.00% No change 1,005 $17K
Bessemer Group Inc. 0.00% Add +651.9% 1,015 $17K
Sterling Capital Management LLC 0.00% Add +372.3% 836 $15K
Golden State Wealth Management, LLC 0.00% No change 828 $14K
GAMMA Investing LLC 0.00% Reduce -17.7% 805 $14K
Covestor Ltd 0.01% No change 658 $12K
Smartleaf Asset Management LLC 0.00% Add +11.2% 635 $11K
Jones Financial Companies LLLP 0.00% Add +26.3% 548 $10K
Vermillion Wealth Management, Inc. 0.00% No change 504 $9K
Rosenberg Matthew Hamilton 0.00% No change 501 $9K
PNC Financial Services Group, Inc. 0.00% Reduce -72.7% 489 $9K
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% No change 424 $7K
US Bancorp \de 0.00% Reduce -52.3% 325 $6K
SBI Securities Co., Ltd. 0.00% Add +38.9% 289 $5K
WPG Advisers, LLC 0.00% New 288 $5K
Cwm, LLC 0.00% Add +139.8% 295 $5K
Nisa Investment Advisors, LLC 0.00% Reduce -21.3% 237 $4K
AdvisorNet Financial, Inc 0.00% New 228 $4K
Gunpowder Capital Management, LLC dba Oliver Wealth Management 0.00% — 200 $3K
EverSource Wealth Advisors, LLC 0.00% Add +40.4% 139 $2K
Arax Advisory Partners 0.00% Reduce -11.3% 94 $2K
Toth Financial Advisory Corp. 0.00% New 90 $2K
J.Safra Asset Management Corp 0.00% No change 83 $1K
Signaturefd, LLC 0.00% Reduce -48.7% 78 $1K
TD Private Client Wealth LLC 0.00% No change 74 $1K
Allworth Financial LP 0.00% Reduce -80.7% 69 $1K
Harbour Investments, Inc. 0.00% Reduce -83.3% 57 $997
Physician Wealth Advisors, Inc. 0.00% No change 55 $962
Litman Gregory Wealth Management LLC 0.00% New 50 $875
Parallel Advisors, LLC 0.00% Reduce -97.3% 50 $875
Assetmark, Inc. 0.00% Reduce -99.8% 44 $770
CVA Family Office, LLC 0.00% No change 40 $700
ORG Partners LLC 0.00% No change 40 $699
Comerica Bank 0.00% Reduce -95.8% 32 $560
Rialto Wealth Management, LLC 0.00% New 29 $508
Marquette Asset Management, LLC 0.00% New 28 $490
United Financial Planning Group LLC 0.00% New 20 $350
JFS Wealth Advisors, LLC 0.00% Reduce -62.9% 13 $228
Versant Capital Management, Inc 0.00% New 10 $175
SHP Wealth Management 0.00% — 10 $175
Hughes Financial Services, LLC 0.00% New 7 $122
Transamerica Financial Advisors, LLC 0.00% Add +50.0% 6 $105
Stone House Investment Management, LLC 0.00% New 6 $105
True Wealth Design, LLC 0.00% Reduce -14.3% 6 $105
Rakuten Securities, Inc. 0.00% No change 5 $87
CIBC Private Wealth Group LLC 0.00% New 3 $52
Rothschild Investment LLC 0.00% Add +100.0% 2 $35
Root Financial Partners, LLC 0.00% Reduce -94.4% 2 $35
Seneschal Advisors, LLC 0.00% No change 2 $35
Bay Harbor Wealth Management, LLC 0.00% Reduce -66.7% 2 $34
SJS Investment Consulting Inc. 0.00% Reduce -85.7% 1 $18
Keating Financial Advisory Services, Inc. 0.00% — 1 $17
1015 Capital Partners, LLC 0.00% — 1 $17

"% of holder's portfolio" is SMMT's weight in each manager's 13F, not the share of Summit Therapeutics Inc. the manager owns.