| Softbank Group Corp. | 0.95% | New | 5,405,406 | $189.2M |
| T. Rowe Price Associates Inc. | 0.02% | New | 5,227,120 | $182.9M |
| NEA Management Company, LLC | 12.04% | New | 4,572,810 | $160.0M |
| Novo Holdings A/S | 7.69% | New | 4,074,419 | $142.6M |
| Revolution Growth Management Company, Inc. | 66.21% | New | 3,660,948 | $128.1M |
| Alphabet Inc. | 2.75% | New | 1,551,102 | $54.3M |
| Norges Bank | 0.01% | New | 1,050,000 | $36.8M |
| Alliancebernstein L.P. | 0.01% | New | 967,265 | $33.9M |
| Lingotto Investment Management LLP | 1.10% | New | 933,859 | $32.7M |
| Massachusetts Financial Services Co. | 0.01% | New | 807,036 | $28.2M |
| Franklin Resources Inc. | 0.01% | New | 802,924 | $28.1M |
| Baron Capital (BAMCO) | 0.08% | New | 784,397 | $27.5M |
| Ameriprise Financial Inc. | 0.01% | New | 682,400 | $23.9M |
| Neuberger Berman Group LLC | 0.02% | New | 662,687 | $23.2M |
| Federated Hermes, Inc. | 0.05% | New | 568,173 | $19.9M |
| ARK Investment Management | 0.16% | New | 522,698 | $18.3M |
| Frontier Capital Management Co. LLC | 0.15% | New | 432,317 | $15.1M |
| Citadel Advisors | 0.01% | New | 418,575 | $14.7M |
| RTW Investments, LP | 0.22% | New | 400,000 | $14.0M |
| LMR Partners LLP | 0.31% | New | 322,275 | $11.3M |
| Amova Asset Management Americas, Inc. | 0.11% | New | 282,223 | $9.9M |
| Perceptive Advisors LLC | 0.23% | New | 275,000 | $9.6M |
| Millennium Management | 0.01% | New | 230,487 | $8.1M |
| Healthcare of Ontario Pension Plan Trust Fund | 0.02% | New | 150,000 | $5.3M |
| Sculptor Capital LP | 0.16% | New | 145,289 | $5.1M |
| Alyeska Investment Group, L.P. | 0.03% | New | 145,237 | $5.1M |
| Marshall Wace, LLP | 0.01% | New | 138,882 | $4.9M |
| Geode Capital Management, LLC | 0.00% | New | 132,632 | $4.6M |
| ArrowMark Colorado Holdings LLC | 0.05% | New | 125,000 | $4.4M |
| Teachers Retirement System of the State of Kentucky | 0.04% | New | 119,000 | $4.2M |
| Jane Street Group, LLC | 0.00% | New | 114,118 | $4.0M |
| Allen Operations LLC | 0.75% | New | 109,459 | $3.8M |
| Barclays PLC | 0.00% | New | 106,000 | $3.7M |
| Monashee Investment Management LLC | 0.47% | New | 102,604 | $3.6M |
| Vanguard Group Inc. | 0.00% | New | 100,000 | $3.5M |
| Sumitomo Mitsui Trust Group, Inc. | 0.00% | New | 72,001 | $2.5M |
| Pier Capital, LLC | 0.34% | New | 65,741 | $2.3M |
| Davidson Kempner Capital Management LP | 0.05% | New | 65,000 | $2.3M |
| Fred Alger Management, LLC | 0.01% | New | 61,920 | $2.2M |
| Ares Management LLC | 0.06% | New | 61,642 | $2.2M |
| Woodline Partners LP | 0.02% | New | 55,000 | $1.9M |
| Dragoneer Investment Group, LLC | 0.03% | New | 50,000 | $1.8M |
| Blackstone Inc. | 0.01% | New | 50,000 | $1.8M |
| Bank of America Corp. | 0.00% | New | 50,000 | $1.8M |
| Tudor Investment Corporation | 0.02% | New | 40,392 | $1.4M |
| Teacher Retirement System of Texas | 0.01% | New | 40,000 | $1.4M |
| Temasek Holdings (Private) Ltd | 0.01% | New | 39,466 | $1.4M |
| Hudson Bay Capital Management LP | 0.01% | New | 39,162 | $1.4M |
| EFG Asset Management (North America) Corp. | 0.23% | New | 38,123 | $1.3M |
| Comerica Bank | 0.01% | New | 34,628 | $1.2M |
| Kodai Capital Management LP | 0.02% | New | 34,100 | $1.2M |
| Employees Retirement System of Texas | 0.01% | New | 29,694 | $1.0M |
| Manufacturers Life Insurance Company, The | 0.00% | New | 27,024 | $946K |
| Cohen & Steers, Inc. | 0.00% | New | 25,000 | $875K |
| Scientech Research LLC | 0.16% | New | 21,605 | $756K |
| Weiss Asset Management LP | 0.06% | New | 20,000 | $700K |
| WINTON GROUP Ltd | 0.04% | New | 18,127 | $634K |
| Squarepoint Ops LLC | 0.00% | New | 18,082 | $633K |
| Morgan Stanley | 0.00% | New | 17,657 | $618K |
| Northwestern University | 0.53% | New | 14,033 | $491K |
| M&T Bank Corp | 0.00% | New | 12,016 | $420K |
| Susquehanna International Group, LLP | 0.00% | New | 9,515 | $333K |
| Oxford Asset Management LLP | 0.26% | New | 7,350 | $257K |
| Raymond James & Associates | 0.00% | New | 6,421 | $225K |
| Bellevue Group AG | 0.00% | New | 5,000 | $175K |
| Legal & General Group Plc | 0.00% | New | 5,000 | $175K |
| US Bancorp \de | 0.00% | New | 4,345 | $152K |
| Sandia Investment Management LP | 0.17% | New | 3,900 | $137K |
| Osaic Holdings, Inc. | 0.00% | New | 2,000 | $70K |
| Royal Bank of Canada | 0.00% | New | 1,996 | $70K |
| JPMorgan Chase & Co. | 0.00% | New | 1,900 | $67K |
| PNC Financial Services Group, Inc. | 0.00% | New | 1,831 | $64K |
| Steward Partners Investment Advisory, LLC | 0.00% | New | 500 | $18K |
| Your Advocates Ltd., LLP | 0.01% | New | 400 | $14K |
| Itau Unibanco Holding S.A. | 0.00% | New | 333 | $12K |
| Ancora Advisors LLC | 0.00% | New | 300 | $11K |
| Wells Fargo & Company | 0.00% | New | 162 | $6K |
| Rothschild Investment LLC | 0.00% | New | 75 | $3K |
| International Assets Investment Management, LLC | 0.00% | New | 50 | $2K |
| Prestige Wealth Management Group LLC | 0.00% | New | 32 | $1K |