Third Harmonic BioTHRD

13F holders, Q4 2024 (December 31)
97holders +12
21new positions
12sold out
4famous investors
$10.29avg. 13F price*

At the end of Q4 2024, 97 institutions reported holding Third Harmonic Bio Inc. (THRD) in their 13F filings, up 12 from Q3 2024. 21 opened new positions and 12 sold out. The largest holders were Atlas Venture Life Science Advisors, LLC ($107.0M), Orbimed Advisors LLC ($59.5M) and General Atlantic, L.P. ($34.7M). 4 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).

Company
Third Harmonic Bio Inc.
CUSIP
88427A107
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150 Q1 2024: 71Q1 2024Q2 2024: 77Q2 2024Q3 2024: 85Q3 2024Q4 2024: 97Q4 2024Q1 2025: 99Q1 2025Q2 2025: 106Q2 2025Q3 2025: 18Q3 2025Q4 2025: 4Q4 2025Q1 2026: 4Q1 2026Q2 2026: 4Q2 2026

Total Exit/New Position Q3 2024 → Q4 2024

InstitutionsTotal Value
New Positions21$24.3M
Exits12$10.5M

All 13F filers, Q3 2024 → Q4 2024: 6,350,123 shares bought and 5,433,343 shares sold, net +916,780 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 97 holders

Atlas Venture Life Science Advisors, LLC 13.06% Reduce -4.6% 10,402,286 $107.0M
Orbimed Advisors LLC 1.23% No change 5,779,071 $59.5M
General Atlantic, L.P. 1.24% Add +14.0% 3,372,323 $34.7M
EcoR1 Capital, LLC 1.31% No change 3,182,444 $32.7M
T. Rowe Price Investment Management, Inc. 0.02% Add +3.5% 2,929,498 $30.1M
FMR LLC 0.00% Add +723.6% 2,536,540 $26.1M
TCG Crossover Management, LLC 2.52% Add +3.7% 2,505,424 $25.8M
BVF Inc. 0.83% Reduce -45.6% 2,372,933 $24.4M
Boxer Capital Management, LLC 1.75% — 2,000,000 $20.6M
BlackRock, Inc. 0.00% Add +1.4% 1,478,393 $15.2M
Vanguard Group Inc. 0.00% Add +15.5% 1,029,987 $10.6M
Deerfield Management Company, L.P. 0.23% New 1,019,700 $10.5M
Ra Capital Management, L.P. 0.13% Reduce -25.0% 960,620 $9.9M
Millennium Management 0.01% Add +685.7% 640,084 $6.6M
Nantahala Capital Management, LLC 0.36% New 501,000 $5.2M
Geode Capital Management, LLC 0.00% Add +9.4% 481,859 $5.0M
State Street Corp. 0.00% Add +5.3% 421,838 $4.3M
T. Rowe Price Associates Inc. 0.00% New 361,890 $3.7M
Schonfeld Strategic Advisors LLC 0.02% Add +25.7% 322,202 $3.3M
Commodore Capital LP 0.18% Reduce -82.5% 237,704 $2.4M
Northern Trust Corp. 0.00% Add +0.5% 192,340 $2.0M
Charles Schwab Investment Management Inc. 0.00% Add +21.5% 173,199 $1.8M
Morgan Stanley 0.00% Reduce -0.3% 162,048 $1.7M
Tang Capital Management LLC 0.10% New 150,000 $1.5M
Renaissance Technologies 0.00% Add +22.0% 127,706 $1.3M
Goldman Sachs Group Inc. 0.00% Add +53.7% 106,667 $1.1M
Citadel Advisors 0.00% Reduce -82.5% 106,534 $1.1M
Ikarian Capital, LLC 0.29% New 100,000 $1.0M
Parkman Healthcare Partners LLC 0.12% Reduce -63.5% 86,707 $892K
TD Asset Management Inc 0.00% Add +126.2% 86,396 $889K
Wellington Management Group LLP 0.00% Add +7.8% 83,392 $858K
Dimensional Fund Advisors LP 0.00% Add +165.2% 71,255 $733K
OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.01% Add +2.8% 53,740 $553K
Acuta Capital Partners, LLC 0.52% Add +221.1% 49,800 $512K
Walleye Capital LLC 0.01% Reduce -41.3% 48,385 $498K
Bank of New York Mellon Corp 0.00% Reduce -0.7% 45,921 $473K
Barclays PLC 0.00% Add +46.5% 42,488 $437K
Bank of America Corp. 0.00% Reduce -8.9% 41,298 $425K
STRS Ohio 0.00% No change 39,400 $405K
Nuveen Asset Management, LLC 0.00% No change 37,246 $383K
Takeda Pharmaceutical Co. Ltd. 1.43% New 36,835 $379K
JPMorgan Chase & Co. 0.00% Add +169.5% 36,147 $372K
Kingswood Wealth Advisors, LLC 0.02% Add +48.8% 31,100 $320K
Manufacturers Life Insurance Company, The 0.00% New 30,211 $311K
State of Wisconsin Investment Board 0.00% Reduce -17.7% 29,800 $307K
BNP Paribas Financial Markets 0.00% New 29,431 $303K
Boothbay Fund Management, LLC 0.01% New 29,350 $302K
Rhumbline Advisers 0.00% Add +0.7% 28,922 $298K
American Century Companies Inc. 0.00% Add +22.3% 27,250 $280K
Citigroup Inc. 0.00% Add +23.0% 20,312 $209K
Deutsche Bank AG 0.00% Add +65.8% 19,538 $201K
Jane Street Group, LLC 0.00% New 19,492 $201K
Squarepoint Ops LLC 0.00% New 19,185 $197K
PDT Partners, LLC 0.02% Reduce -20.0% 18,642 $192K
Susquehanna International Group, LLP 0.00% New 16,823 $173K
HSBC Holdings PLC 0.00% Add +46.4% 16,375 $169K
XTX Topco Ltd 0.01% New 15,884 $163K
UBS Group AG 0.00% Add +22.3% 13,316 $137K
MetLife Investment Management, LLC 0.00% No change 12,859 $132K
SG Americas Securities, LLC 0.00% Reduce -29.1% 12,050 $124K
Alliancebernstein L.P. 0.00% No change 11,930 $123K
Wells Fargo & Company 0.00% Add +27.9% 11,637 $120K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Add +5.5% 11,355 $117K
Verition Fund Management LLC 0.00% New 11,240 $116K
D. E. Shaw & Co. 0.00% Reduce -21.2% 11,000 $113K
Quarry LP 0.02% New 10,000 $103K
Corebridge Financial, Inc. 0.00% Reduce -7.0% 9,857 $101K
AlphaQuest LLC 0.01% Reduce -33.3% 9,773 $101K
China Universal Asset Management Co., Ltd. 0.01% Add +20.9% 9,554 $98K
Virtus Advisers, LLC 0.03% New 6,320 $65K
Royal Bank of Canada 0.00% Add +89.9% 6,005 $62K
New York State Common Retirement Fund 0.00% No change 5,976 $61K
Tower Research Capital LLC (TRC) 0.00% Add +612.1% 4,949 $51K
Nisa Investment Advisors, LLC 0.00% Add +0.9% 4,477 $46K
Police & Firemen's Retirement System of New Jersey 0.00% — 3,986 $41K
Ameritas Investment Partners, Inc. 0.00% No change 2,017 $21K
Legal & General Group Plc 0.00% No change 1,954 $20K
R Squared Ltd 0.02% — 1,840 $19K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +1.1% 1,502 $15K
Avior Wealth Management, LLC 0.00% Add +598.1% 1,487 $15K
California State Teachers Retirement System 0.00% No change 1,437 $15K
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% Reduce -18.8% 1,275 $13K
GF Fund Management Co. LTD. 0.00% — 946 $10K
Amalgamated Bank 0.00% No change 665 $7K
Sterling Capital Management LLC 0.00% Add +907.9% 635 $7K
PNC Financial Services Group, Inc. 0.00% No change 580 $6K
Russell Investments Group, Ltd. 0.00% No change 343 $4K
Daiwa Securities Group Inc. 0.00% No change 149 $2K
Arax Advisory Partners 0.00% No change 171 $2K
Raffa Wealth Management, LLC 0.00% Reduce -21.1% 150 $2K
Creative Planning 0.00% New 130 $1K
Comerica Bank 0.00% New 115 $1K
Simplex Trading, LLC 0.00% New 153 $1K
Cwm, LLC 0.00% Reduce -41.0% 49 $1K
GAMMA Investing LLC 0.00% Reduce -19.2% 97 $998
SBI Securities Co., Ltd. 0.00% — 30 $309
Macquarie Group Ltd. 0.00% New 4,040 $42

"% of holder's portfolio" is THRD's weight in each manager's 13F, not the share of Third Harmonic Bio Inc. the manager owns.