ZymeworksZYME
13F holders, Q4 2024 (December 31)173holders +10
23new positions
19sold out
6famous investors
$14.64avg. 13F price*
At the end of Q4 2024, 173 institutions reported holding Zymeworks Inc. (ZYME) in their 13F filings, up 10 from Q3 2024. 23 opened new positions and 19 sold out. The largest holders were EcoR1 Capital, LLC ($220.0M), Redmile Group, LLC ($70.9M) and BVF Inc. ($63.1M). 6 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Zymeworks Inc.
- CUSIP
- 98985Y108
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2024 → Q4 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 23 | $22.9M |
| Exits | 19 | $14.9M |
All 13F filers, Q3 2024 → Q4 2024: 5,336,264 shares bought and 5,545,375 shares sold, net −209,111 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 173 holders
| EcoR1 Capital, LLC | 8.80% | Add +11.8% | 15,028,079 | $220.0M |
| Redmile Group, LLC | 4.94% | Reduce -5.1% | 4,840,463 | $70.9M |
| BVF Inc. | 2.14% | Reduce -6.5% | 4,308,935 | $63.1M |
| Morgan Stanley | 0.00% | Reduce -17.7% | 4,201,437 | $61.5M |
| BlackRock, Inc. | 0.00% | Reduce -1.8% | 4,184,956 | $61.3M |
| Rubric Capital Management LP | 1.04% | No change | 3,917,331 | $57.3M |
| Vanguard Group Inc. | 0.00% | Reduce -12.8% | 2,493,288 | $36.5M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.08% | Add +9.9% | 2,137,653 | $31.3M |
| Perceptive Advisors LLC | 0.87% | Reduce -2.3% | 2,130,020 | $31.2M |
| Deutsche Bank AG | 0.01% | Add +1.2% | 1,546,772 | $22.6M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -10.4% | 1,365,111 | $20.0M |
| Farallon Capital Management, L.L.C. | 0.10% | Reduce -2.3% | 1,329,974 | $19.5M |
| Nextech Invest Ltd. | 2.65% | No change | 1,113,946 | $16.3M |
| Tang Capital Management LLC | 1.07% | No change | 1,100,000 | $16.1M |
| State Street Corp. | 0.00% | Reduce -7.4% | 1,084,961 | $15.9M |
| Samsara Biocapital, LLC | 2.01% | No change | 1,000,000 | $14.6M |
| Dimensional Fund Advisors LP | 0.00% | Add +14.5% | 972,742 | $14.2M |
| Prosight Management, LP | 3.36% | Reduce -10.6% | 820,000 | $12.0M |
| Bridgeway Capital Management, LLC | 0.25% | Add +2.3% | 759,653 | $11.1M |
| Geode Capital Management, LLC | 0.00% | Reduce -3.4% | 689,884 | $10.1M |
| Assenagon Asset Management S.A. | 0.02% | Add +94.0% | 642,251 | $9.4M |
| Blackstone Inc. | 0.04% | Add +2171.4% | 569,715 | $8.3M |
| Walleye Capital LLC | 0.07% | New | 452,804 | $6.6M |
| Granahan Investment Management, LLC | 0.25% | Reduce -33.0% | 411,120 | $6.0M |
| Northern Trust Corp. | 0.00% | Add +6.4% | 394,830 | $5.8M |
| Jupiter Asset Management Ltd. | 0.05% | Reduce -13.4% | 369,499 | $5.4M |
| Jacobs Levy Equity Management, Inc. | 0.02% | Reduce -31.9% | 356,168 | $5.2M |
| Empowered Funds, LLC | 0.08% | Add +5.1% | 352,753 | $5.2M |
| Schroder Investment Management Group | 0.00% | New | 337,161 | $4.9M |
| Point72 Asset Management | 0.01% | Add +565.8% | 330,127 | $4.8M |
| Platinum Investment Management Ltd. | 0.26% | Reduce -6.4% | 306,460 | $4.5M |
| Renaissance Technologies | 0.01% | Add +54.8% | 285,700 | $4.2M |
| Silvercrest Asset Management Group LLC | 0.03% | Reduce -1.0% | 282,345 | $4.1M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -0.6% | 249,960 | $3.7M |
| Acadian Asset Management LLC | 0.01% | Reduce -48.2% | 230,970 | $3.4M |
| Hillsdale Investment Management Inc. | 0.17% | New | 230,025 | $3.4M |
| Barclays PLC | 0.00% | Add +43.1% | 220,890 | $3.2M |
| Wellington Management Group LLP | 0.00% | Reduce -9.9% | 219,098 | $3.2M |
| Panagora Asset Management Inc. | 0.01% | Add +112.5% | 214,338 | $3.1M |
| Nuveen Asset Management, LLC | 0.00% | Add +0.4% | 207,023 | $3.0M |
| Picton Mahoney Asset Management | 0.11% | Reduce -15.6% | 206,569 | $3.0M |
| Norges Bank | 0.00% | No change | 201,700 | $3.0M |
| Vestal Point Capital, LP | 0.16% | Reduce -69.9% | 185,000 | $2.7M |
| Federated Hermes, Inc. | 0.01% | Add +1.9% | 181,626 | $2.7M |
| UBS Group AG | 0.00% | Add +23.1% | 166,896 | $2.4M |
| Wells Fargo & Company | 0.00% | Reduce -7.5% | 164,058 | $2.4M |
| Kennedy Capital Management LLC | 0.05% | Reduce -2.5% | 139,953 | $2.0M |
| O'shaughnessy Asset Management, LLC | 0.02% | Reduce -8.5% | 132,577 | $1.9M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -1.1% | 131,306 | $1.9M |
| Ameriprise Financial Inc. | 0.00% | Reduce -11.5% | 121,526 | $1.8M |
| Bank of New York Mellon Corp | 0.00% | Reduce -51.7% | 120,683 | $1.8M |
| JPMorgan Chase & Co. | 0.00% | Add +185.1% | 111,983 | $1.6M |
| Rhumbline Advisers | 0.00% | Add +18.1% | 103,876 | $1.5M |
| Trexquant Investment LP | 0.02% | New | 101,996 | $1.5M |
| Susquehanna Fundamental Investments, LLC | 0.02% | — | 97,553 | $1.4M |
| North Growth Management Ltd. | 0.27% | No change | 97,000 | $1.4M |
| HRT Financial LP | 0.01% | Add +96.6% | 95,974 | $1.4M |
| Swiss National Bank | 0.00% | No change | 90,200 | $1.3M |
| Citigroup Inc. | 0.00% | Add +4.1% | 83,136 | $1.2M |
| Credit Agricole S A | 0.00% | No change | 75,000 | $1.1M |
| Ritholtz Wealth Management | 0.03% | Add +6.1% | 74,466 | $1.1M |
| Invesco Ltd. | 0.00% | Reduce -57.4% | 69,382 | $1.0M |
| Acuta Capital Partners, LLC | 0.99% | New | 67,240 | $984K |
| State of Wisconsin Investment Board | 0.00% | Reduce -23.2% | 65,381 | $957K |
| Stifel Financial Corp. | 0.00% | Reduce -12.7% | 64,330 | $942K |
| Fisher Asset Management | 0.00% | No change | 63,600 | $931K |
| Royal Bank of Canada | 0.00% | Reduce -1.5% | 60,926 | $893K |
| Raymond James Financial Inc. | 0.00% | — | 60,642 | $888K |
| Voya Investment Management LLC | 0.00% | Add +207.7% | 59,514 | $871K |
| Citadel Advisors | 0.00% | Add +180.5% | 58,358 | $854K |
| Envestnet Asset Management Inc. | 0.00% | Reduce -17.6% | 54,090 | $792K |
| Victory Capital Management Inc. | 0.00% | Reduce -5.2% | 51,580 | $755K |
| Susquehanna International Group, LLP | 0.00% | Add +214.4% | 51,516 | $754K |
| Public Employees Retirement System of Ohio | 0.00% | Reduce -17.1% | 50,583 | $741K |
| Alliancebernstein L.P. | 0.00% | No change | 50,030 | $732K |
| STRS Ohio | 0.00% | New | 49,000 | $717K |
| Jump Financial, LLC | 0.02% | New | 48,612 | $712K |
| Legal & General Group Plc | 0.00% | Add +19.0% | 47,082 | $689K |
| Russell Investments Group, Ltd. | 0.00% | Reduce -9.7% | 44,945 | $658K |
| California State Teachers Retirement System | 0.00% | Reduce -0.9% | 43,783 | $641K |
| Voloridge Investment Management, LLC | 0.00% | New | 43,708 | $640K |
| American Century Companies Inc. | 0.00% | New | 39,942 | $585K |
| Tejara Capital Ltd | 0.37% | New | 38,537 | $564K |
| Polar Asset Management Partners Inc. | 0.01% | New | 36,000 | $527K |
| MetLife Investment Management, LLC | 0.00% | Add +6.4% | 33,946 | $497K |
| Intech Investment Management LLC | 0.00% | Add +60.0% | 33,858 | $496K |
| XTX Topco Ltd | 0.04% | New | 33,702 | $493K |
| Bank of America Corp. | 0.00% | Reduce -54.5% | 31,700 | $464K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +1.0% | 30,958 | $453K |
| Commonwealth Equity Services, LLC | 0.00% | Add +16.1% | 30,960 | $453K |
| Cresset Asset Management, LLC | 0.00% | Reduce -21.8% | 30,806 | $451K |
| Journey Strategic Wealth LLC | 0.02% | No change | 28,897 | $423K |
| Massachusetts Financial Services Co. | 0.00% | Reduce -65.7% | 27,385 | $401K |
| Corebridge Financial, Inc. | 0.00% | Reduce -9.3% | 27,115 | $397K |
| SG Americas Securities, LLC | 0.00% | Add +30.4% | 26,782 | $392K |
| AQR Capital Management | 0.00% | Add +4.9% | 26,074 | $382K |
| Bank of Montreal | 0.00% | Reduce -9.2% | 25,948 | $380K |
| Jane Street Group, LLC | 0.00% | Reduce -71.2% | 23,127 | $339K |
| Schonfeld Strategic Advisors LLC | 0.00% | New | 22,800 | $334K |
| FMR LLC | 0.00% | Add +558.5% | 21,966 | $322K |
| Qube Research & Technologies Ltd | 0.00% | New | 21,868 | $320K |
| T. Rowe Price Associates Inc. | 0.00% | Add +17.6% | 21,583 | $316K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -4.9% | 20,958 | $307K |
| D. E. Shaw & Co. | 0.00% | Reduce -4.3% | 20,840 | $305K |
| Prudential Financial Inc. | 0.00% | New | 19,660 | $288K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +14.8% | 19,611 | $287K |
| ProShare Advisors LLC | 0.00% | Reduce -36.9% | 18,623 | $273K |
| Janus Henderson Group PLC | 0.00% | No change | 18,200 | $266K |
| Verition Fund Management LLC | 0.00% | New | 15,814 | $232K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 15,340 | $225K |
| Monaco Asset Management SAM | 0.10% | Reduce -95.0% | 15,000 | $220K |
| China Universal Asset Management Co., Ltd. | 0.02% | Add +6.9% | 14,605 | $214K |
| One Wealth Advisors, LLC | 0.03% | Reduce -42.6% | 13,979 | $205K |
| Teacher Retirement System of Texas | 0.00% | Add +19.2% | 13,743 | $201K |
| Arizona State Retirement System | 0.00% | Add +1.4% | 13,412 | $196K |
| Exchange Traded Concepts, LLC | 0.00% | No change | 13,386 | $196K |
| New York State Common Retirement Fund | 0.00% | Add +42.7% | 13,371 | $196K |
| Shell Asset Management Co. | 0.01% | No change | 12,357 | $181K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | — | 11,669 | $171K |
| James Investment Research, Inc. | 0.02% | No change | 10,578 | $155K |
| KLP Kapitalforvaltning As | 0.00% | — | 10,300 | $151K |
| Janney Montgomery Scott LLC | 0.00% | No change | 10,267 | $150K |
| TPG Financial Advisors, LLC | 0.06% | Reduce -9.1% | 10,017 | $147K |
| Jain Global LLC | 0.00% | — | 10,010 | $147K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +343.9% | 9,704 | $142K |
| BNP Paribas Financial Markets | 0.00% | New | 7,363 | $108K |
| Compagnie Lombard Odier SCmA | 0.00% | Reduce -30.0% | 7,000 | $102K |
| Virtus Advisers, LLC | 0.03% | Reduce -44.3% | 5,633 | $82K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 5,616 | $82K |
| Northwest & Ethical Investments L.P. | 0.00% | Reduce -14.1% | 5,471 | $80K |
| Clearstead Advisors, LLC | 0.00% | No change | 5,000 | $73K |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 3,843 | $55K |
| AlphaQuest LLC | 0.01% | Add +480.2% | 2,808 | $41K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Reduce -10.7% | 2,295 | $33K |
| Amalgamated Bank | 0.00% | No change | 1,799 | $26K |
| Sterling Capital Management LLC | 0.00% | Add +781.5% | 1,719 | $25K |
| GF Fund Management Co. LTD. | 0.00% | — | 1,446 | $21K |
| Simplex Trading, LLC | 0.00% | Reduce -28.9% | 1,087 | $15K |
| Curio Wealth, LLC | 0.01% | — | 1,000 | $15K |
| Group One Trading LLC | 0.00% | Reduce -97.3% | 800 | $12K |
| Osaic Holdings, Inc. | 0.00% | Reduce -15.6% | 717 | $10K |
| Brooklyn Investment Group | 0.00% | New | 589 | $9K |
| National Bank of Canada | 0.00% | Reduce -3.7% | 548 | $8K |
| GAMMA Investing LLC | 0.00% | Add +23.1% | 533 | $8K |
| US Bancorp \de | 0.00% | Reduce -46.0% | 488 | $7K |
| Truvestments Capital LLC | 0.00% | Add +67.6% | 434 | $6K |
| Lindbrook Capital, LLC | 0.00% | No change | 371 | $5K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -4.9% | 332 | $5K |
| Parallel Advisors, LLC | 0.00% | No change | 329 | $5K |
| TD Waterhouse Canada Inc. | 0.00% | No change | 311 | $5K |
| PNC Financial Services Group, Inc. | 0.00% | Add +7000.0% | 284 | $4K |
| HighMark Wealth Management LLC | 0.00% | No change | 280 | $4K |
| Daiwa Securities Group Inc. | 0.00% | No change | 286 | $4K |
| Smartleaf Asset Management LLC | 0.00% | Add +71.1% | 243 | $4K |
| Cwm, LLC | 0.00% | Add +168.1% | 193 | $3K |
| Arax Advisory Partners | 0.00% | Reduce -21.8% | 169 | $2K |
| Cornerstone Planning Group LLC | 0.00% | No change | 161 | $2K |
| Farther Finance Advisors, LLC | 0.00% | No change | 150 | $2K |
| Eagle Bay Advisors LLC | 0.00% | No change | 110 | $2K |
| Aster Capital Management (DIFC) Ltd | 0.00% | Reduce -90.7% | 70 | $1K |
| Federation des caisses Desjardins du Quebec | 0.00% | New | 60 | $878 |
| Creative Planning | 0.00% | New | 57 | $834 |
| Steward Partners Investment Advisory, LLC | 0.00% | No change | 53 | $776 |
| Amundi | 0.00% | New | 52 | $735 |
| Rothschild Investment LLC | 0.00% | Reduce -16.7% | 50 | $732 |
| Allworth Financial LP | 0.00% | No change | 34 | $499 |
| WR Wealth Planners, LLC | 0.00% | No change | 28 | $410 |
| Richards, Merrill & Peterson, Inc. | 0.00% | — | 20 | $293 |
| CoreCap Advisors, LLC | 0.00% | No change | 18 | $264 |
| EverSource Wealth Advisors, LLC | 0.00% | New | 10 | $146 |
| SBI Securities Co., Ltd. | 0.00% | — | 10 | $146 |
| Innovative Advisory Group, LLC | 0.00% | — | 8 | $117 |
| Covestor Ltd | 0.00% | Add +50.0% | 27 | $0 |
"% of holder's portfolio" is ZYME's weight in each manager's 13F, not the share of Zymeworks Inc. the manager owns.