ZymeworksZYME
13F holders, Q1 2026 (March 31)212holders +2
34new positions
34sold out
5famous investors
$25.04avg. 13F price*
At the end of Q1 2026, 212 institutions reported holding Zymeworks Inc. (ZYME) in their 13F filings, up 2 from Q4 2025. 34 opened new positions and 34 sold out. The largest holders were EcoR1 Capital, LLC ($575.2M), Rubric Capital Management LP ($175.3M) and BlackRock, Inc. ($114.0M). 5 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).
- Company
- Zymeworks Inc.
- CUSIP
- 98985Y108
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 34 | $46.3M |
| Exits | 34 | $139.3M |
All 13F filers, Q4 2025 → Q1 2026: 6,264,583 shares bought and 7,398,077 shares sold, net −1,133,494 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 212 holders
| EcoR1 Capital, LLC | 24.58% | No change | 22,970,388 | $575.2M |
| Rubric Capital Management LP | 2.15% | Add +21.7% | 7,000,000 | $175.3M |
| BlackRock, Inc. | 0.00% | Reduce -0.9% | 4,553,888 | $114.0M |
| BVF Inc. | 2.98% | Reduce -5.2% | 3,734,142 | $93.5M |
| Perceptive Advisors LLC | 1.74% | Add +7.6% | 3,510,078 | $87.9M |
| Morgan Stanley | 0.00% | Reduce -4.3% | 2,480,568 | $62.1M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.06% | Add +4.7% | 1,908,039 | $47.8M |
| Vanguard Capital Management LLC | 0.00% | — | 1,705,580 | $42.7M |
| Citadel Advisors | 0.02% | Add +350.4% | 1,150,018 | $28.8M |
| Dimensional Fund Advisors LP | 0.01% | Reduce -1.7% | 1,139,135 | $28.5M |
| Nextech Invest Ltd. | 1.96% | No change | 1,113,946 | $27.9M |
| State Street Corp. | 0.00% | Reduce -2.5% | 1,011,777 | $25.3M |
| Capricorn Fund Managers Ltd | 3.93% | Reduce -1.5% | 1,007,210 | $25.2M |
| Deutsche Bank AG | 0.01% | Reduce -42.3% | 921,250 | $23.1M |
| Arrowstreet Capital, Limited Partnership | 0.01% | Add +6.3% | 743,898 | $18.6M |
| Assenagon Asset Management S.A. | 0.03% | Add +12.4% | 727,986 | $18.2M |
| FMR LLC | 0.00% | Add +19.1% | 667,153 | $16.7M |
| Geode Capital Management, LLC | 0.00% | Add +1.9% | 659,940 | $16.5M |
| Nuveen, LLC | 0.00% | Add +0.5% | 651,662 | $16.3M |
| Goldman Sachs Group Inc. | 0.00% | Add +42.7% | 599,486 | $15.0M |
| MPM Bioimpact LLC | 1.09% | New | 565,249 | $14.2M |
| Prosight Management, LP | 2.21% | Add +1.6% | 539,049 | $13.5M |
| Qube Research & Technologies Ltd | 0.02% | Add +7.9% | 511,937 | $12.8M |
| Vanguard Portfolio Management LLC | 0.00% | — | 499,875 | $12.5M |
| Redmile Group, LLC | 0.82% | No change | 491,654 | $12.3M |
| Hillsdale Investment Management Inc. | 0.24% | Add +45.3% | 345,622 | $8.7M |
| SummitTX Capital, L.P. | 0.26% | Add +43.3% | 321,427 | $8.0M |
| Northern Trust Corp. | 0.00% | Add +4.0% | 320,210 | $8.0M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -0.3% | 319,385 | $8.0M |
| Royce & Associates LP | 0.07% | New | 299,202 | $7.5M |
| Picton Mahoney Asset Management | 0.07% | Add +4.9% | 256,690 | $6.4M |
| Granahan Investment Management, LLC | 0.30% | Add +11.8% | 250,773 | $6.3M |
| HRT Financial LP | 0.01% | Add +96.5% | 237,889 | $6.0M |
| Bank of America Corp. | 0.00% | Add +164.5% | 236,754 | $5.9M |
| D. E. Shaw & Co. | 0.01% | Add +5.3% | 235,621 | $5.9M |
| Jane Street Group, LLC | 0.01% | Add +222.2% | 226,967 | $5.7M |
| Panagora Asset Management Inc. | 0.02% | Add +164.1% | 206,854 | $5.2M |
| Man Group plc | 0.01% | Add +152.1% | 189,890 | $4.8M |
| Wells Fargo & Company | 0.00% | Reduce -9.0% | 189,636 | $4.7M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -16.2% | 185,124 | $4.6M |
| Federated Hermes, Inc. | 0.01% | Add +19.5% | 182,410 | $4.6M |
| Raymond James Financial Inc. | 0.00% | Reduce -6.0% | 176,411 | $4.4M |
| UBS Group AG | 0.00% | Reduce -38.4% | 171,779 | $4.3M |
| Silvercrest Asset Management Group LLC | 0.03% | Reduce -10.0% | 163,649 | $4.1M |
| Kennedy Capital Management LLC | 0.08% | Add +1.9% | 148,226 | $3.7M |
| XTX Topco Ltd | 0.06% | Add +53.9% | 143,882 | $3.6M |
| Diadema Partners LP | 1.47% | New | 142,132 | $3.6M |
| Wellington Management Group LLP | 0.00% | Reduce -23.7% | 138,690 | $3.5M |
| Invesco Ltd. | 0.00% | Reduce -51.2% | 125,630 | $3.1M |
| Bank of New York Mellon Corp | 0.00% | Reduce -3.1% | 124,105 | $3.1M |
| Citigroup Inc. | 0.00% | Add +2.8% | 114,327 | $2.9M |
| JPMorgan Chase & Co. | 0.00% | Add +225.8% | 114,072 | $2.8M |
| Platinum Investment Management Ltd. | 0.66% | No change | 105,184 | $2.6M |
| Tema ETFs LLC | 0.18% | Add +38.1% | 104,931 | $2.6M |
| Tidal Investments LLC | 0.01% | New | 104,931 | $2.6M |
| Fisher Asset Management | 0.00% | Add +48.7% | 101,439 | $2.5M |
| Susquehanna Portfolio Strategies, LLC | 0.04% | No change | 99,795 | $2.5M |
| AQR Capital Management | 0.00% | Reduce -0.5% | 90,669 | $2.3M |
| Kornitzer Capital Management Inc. | 0.05% | No change | 88,800 | $2.2M |
| Vanguard Fiduciary Trust Co. | 0.00% | — | 84,403 | $2.1M |
| Squarepoint Ops LLC | 0.00% | New | 83,146 | $2.1M |
| Mackenzie Financial Corp. | 0.00% | Add +82.0% | 82,726 | $2.1M |
| Verdad Advisers, LP | 2.33% | New | 82,698 | $2.1M |
| Principal Financial Group Inc. | 0.00% | New | 78,547 | $2.0M |
| Franklin Resources Inc. | 0.00% | Add +31.6% | 77,659 | $1.9M |
| Stifel Financial Corp. | 0.00% | Add +1.2% | 76,756 | $1.9M |
| Rhumbline Advisers | 0.00% | Reduce -0.1% | 75,399 | $1.9M |
| Credit Agricole S A | 0.01% | No change | 75,000 | $1.9M |
| Ameriprise Financial Inc. | 0.00% | Reduce -34.4% | 74,222 | $1.9M |
| Swiss National Bank | 0.00% | No change | 74,200 | $1.9M |
| American Century Companies Inc. | 0.00% | Add +20.4% | 70,851 | $1.8M |
| State of Wisconsin Investment Board | 0.00% | Reduce -12.5% | 66,106 | $1.7M |
| Alliancebernstein L.P. | 0.00% | Add +11.7% | 55,896 | $1.5M |
| Dana Investment Advisors, Inc. | 0.04% | Add +16.1% | 56,107 | $1.4M |
| Campbell & CO Investment Adviser LLC | 0.08% | Add +63.4% | 54,883 | $1.4M |
| Russell Investments Group, Ltd. | 0.00% | Reduce -18.7% | 47,450 | $1.2M |
| Royal Bank of Canada | 0.00% | Reduce -14.0% | 47,360 | $1.2M |
| Segall Bryant & Hamill, LLC | 0.02% | New | 45,726 | $1.1M |
| North Growth Management Ltd. | 0.17% | Add +2.2% | 46,000 | $1.1M |
| Jacobs Levy Equity Management, Inc. | 0.00% | New | 42,786 | $1.1M |
| Victory Capital Management Inc. | 0.00% | Reduce -1.2% | 42,404 | $1.1M |
| Envestnet Asset Management Inc. | 0.00% | Reduce -1.0% | 40,419 | $1.0M |
| Manatuck Hill Partners, LLC | 0.33% | New | 40,000 | $1.0M |
| Los Angeles Capital Management LLC | 0.00% | Add +10171.3% | 39,750 | $995K |
| Quantinno Capital Management LP | 0.00% | Add +37.2% | 39,640 | $993K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +92.7% | 39,355 | $985K |
| Connor, Clark & Lunn Investment Management Ltd. | 0.00% | New | 37,919 | $949K |
| HSBC Holdings PLC | 0.00% | Add +111.4% | 37,777 | $940K |
| California State Teachers Retirement System | 0.00% | Reduce -1.0% | 37,389 | $936K |
| O'shaughnessy Asset Management, LLC | 0.00% | Reduce -13.8% | 37,129 | $930K |
| Tudor Investment Corporation | 0.01% | Add +21.6% | 36,875 | $923K |
| HighTower Advisors, LLC | 0.00% | New | 36,262 | $908K |
| Persistent Asset Partners Ltd | 0.35% | Add +389.2% | 35,935 | $900K |
| T. Rowe Price Associates Inc. | 0.00% | Add +23.3% | 35,487 | $889K |
| HighVista Strategies LLC | 0.24% | New | 34,085 | $853K |
| Vinva Investment Management Ltd | 0.01% | Add +97.2% | 24,090 | $851K |
| Martingale Asset Management L P | 0.02% | New | 32,764 | $820K |
| Creative Planning | 0.00% | Add +14.5% | 32,394 | $811K |
| Marshall Wace, LLP | 0.00% | New | 32,223 | $807K |
| Manufacturers Life Insurance Company, The | 0.00% | Add +81.2% | 31,592 | $791K |
"% of holder's portfolio" is ZYME's weight in each manager's 13F, not the share of Zymeworks Inc. the manager owns.