Braidwell LP

In its 13F for Q3 2024 (holdings as of September 30, 2024, filed November 14, 2024), Braidwell LP reported 65 stock positions worth $2.3 billion. Its top holding was CG Oncology (CGON) at 5.2% of the portfolio, followed by Xenon Pharmaceuticals (XENE, 4.6%) and Neurocrine Biosciences (NBIX, 4.6%). Compared with Q2 2024, it opened 15 new positions, sold out of 8, added to 24 and reduced 22. The biggest buy was Apellis Pharmaceuticals (APLS, shares +411%) and the biggest sale an exit from Thermo Fisher Scientific (TMO).

Most Recent 13F
Q2 2026
Location
STAMFORD, CT
CIK
0001920938
Portfolio Value
$2.3B (Q3 2024)
SEC Filing
0001920938-24-000006 ↗ filed Nov 14, 2024

Holdings Value

0$1.0B$2.0B$3.0B Q1 2024: $1.8B Q1 2024 Q2 2024: $2.0B Q2 2024 Q3 2024: $2.3B $2.3B Q3 2024 Q4 2024: $2.2B Q4 2024 Q1 2025: $1.9B Q1 2025 Q2 2025: $2.1B Q2 2025 Q3 2025: $2.5B Q3 2025 Q4 2025: $2.6B Q4 2025 Q1 2026: $2.6B Q1 2026 Q2 2026: $2.6B Q2 2026

Holdings 65 stocks · $2.3B

CGON CG Oncology Inc. 5.15% 3,170,875 $119.6M Reduce -4.2%
XENE Xenon Pharmaceuticals Inc. 4.59% 2,707,255 $106.6M Add +5.7%
NBIX Neurocrine Biosciences Inc. 4.55% 917,674 $105.7M Add +20.9%
APGE Apogee Therapeutics Inc. 4.16% 1,643,226 $96.5M Reduce -31.3%
APLS Apellis Pharmaceuticals Inc. 3.88% 3,125,183 $90.1M Add +410.8%
ALGN Align Technology Inc. 3.41% 311,679 $79.3M Add +13.3%
GH Guardant Health Inc. 3.30% 3,342,124 $76.7M Add +19.0%
LEGN Legend Biotech Corp.-ADR 3.23% 1,541,551 $75.1M Reduce -7.7%
VKTX Viking Therapeutics Inc. 3.15% 1,156,977 $73.2M Add +4.5%
KNSA Kiniksa Pharmaceuticals Inte 3.11% 2,894,513 $72.3M Add +40.6%
PEN Penumbra Inc. 3.02% 361,428 $70.2M Add +70.0%
MRVI Maravai Lifesciences Hldgs-A 2.99% 8,353,287 $69.4M Reduce -7.4%
DAWN Day One Biopharmaceuticals I 2.92% 4,873,853 $67.9M Add +60.5%
SYRE Spyre Therapeutics Inc. 2.77% 2,189,836 $64.4M Reduce -12.9%
RGEN Repligen Corp. 2.54% 396,781 $59.0M Add +22.6%
IRTC Irhythm Holdings Inc. 2.50% 782,557 $58.1M Add +48.7%
ARGX Argenx SE - ADR 2.26% 96,724 $52.4M Reduce -42.1%
EWTX Edgewise Therapeutics Inc. 2.25% 1,958,310 $52.3M New
INSP Inspire Medical Systems Inc. 2.17% 238,911 $50.4M Reduce -37.0%
SRPT Sarepta Therapeutics Inc. 1.99% 370,400 $46.3M Add +352.3%
ISRG Intuitive Surgical Inc. 1.93% 91,300 $44.9M Reduce -9.2%
AVDL Avadel Pharmaceuticals Ltd. 1.91% 3,388,939 $44.4M Add +16.9%
BCAX Bicara Therapeutics Inc. 1.82% 1,657,600 $42.2M New
KROS Keros Therapeutics Inc. 1.77% 707,240 $41.1M Reduce -28.0%
GKOS Glaukos Corp. 1.75% 311,616 $40.6M Reduce -37.3%
MDGL Madrigal Pharmaceuticals Inc. 1.68% 183,818 $39.0M New
PCVX Vaxcyte Inc. 1.46% 297,568 $34.0M Reduce -63.2%
REPL Replimune Group Inc. 1.45% 3,070,837 $33.7M Add +203.0%
ARVN Arvinas Inc. 1.36% 1,284,472 $31.6M Add +148.3%
KRYS Krystal Biotech Inc. 1.32% 168,691 $30.7M Add +57.4%
KIDS Orthopediatrics Corp. 1.29% 1,107,770 $30.0M No change
DXCM Dexcom Inc. 1.27% 441,086 $29.6M New
BNTX Biontech SE-ADR 1.27% 247,750 $29.4M New
FNA Paragon 28 Inc. 1.19% 4,135,109 $27.6M Reduce -0.4%
RLAY Relay Therapeutics Inc. 1.07% 3,499,427 $24.8M Add +16.4%
ATEC Alphatec Holdings Inc. 0.97% 4,041,065 $22.5M Add +84.1%
HROW Harrow Inc. 0.85% 439,638 $19.8M Add +47.9%
CGEM Cullinan Therapeutics Inc. 0.85% 1,176,173 $19.7M Add +567.6%
EXAS Exact Sciences Corp. 0.84% 286,178 $19.5M Reduce -74.9%
OCUL Ocular Therapeutix Inc. 0.84% 2,239,770 $19.5M Add +36.3%
IMTX Immatics NV 0.81% 1,647,565 $18.8M New
IRWD Ironwood Pharmaceuticals Inc. 0.79% 4,438,232 $18.3M No change
BSX Boston Scientific Corp. 0.68% 189,200 $15.9M New
DNTH Dianthus Therapeutics Inc. 0.58% 493,687 $13.5M Add +34.6%
FDMT 4D Molecular Therapeutics Inc. 0.57% 1,225,448 $13.2M Add +231.7%
CELC Celcuity Inc. 0.57% 884,306 $13.2M Add +71.2%
ORKA Oruka Therapeutics Inc. 0.54% 515,726 $12.6M New
ALEC Alector Inc. 0.43% 2,158,245 $10.1M Reduce -9.3%
ZURA Zura Bio Ltd. 0.43% 2,472,806 $10.0M New
PODD Insulet Corp. 0.43% 42,500 $9.9M New
NVRO Nevro LLC filed as NEVRO CORP 0.41% 1,698,768 $9.5M No change
CSTL Castle Biosciences Inc. 0.41% 331,986 $9.5M Reduce -20.2%
XNCR Xencor Inc. 0.40% 466,448 $9.4M New
JSPR Jasper Therapeutics Inc. 0.39% 483,300 $9.1M New
BBIO Bridgebio Pharma Inc. 0.33% 298,400 $7.6M Reduce -13.7%
LXEO Lexeo Therapeutics Inc. 0.28% 728,777 $6.6M Reduce -47.3%
LUNG Pulmonx Corp. 0.27% 752,541 $6.2M No change
SKIN Skinhealth Systems Inc. filed as THE BEAUTY HEALTH COMPANY 0.25% 4,049,694 $5.8M Reduce -20.9%
FULC Fulcrum Therapeutics Inc. 0.16% 1,069,158 $3.8M New
VERV Verve Therapeutics Inc. 0.13% 623,980 $3.0M New
IOVA Iovance Biotherapeutics Inc. 0.09% 217,928 $2.0M Reduce -85.1%
HLVX Hillevax Inc. 0.08% 1,064,000 $1.9M New
LXRX Lexicon Pharmaceuticals Inc. 0.05% 801,584 $1.3M Reduce -90.3%
DBV TECHNOLOGIES S A 0.05% 1,630,542 $1.1M Reduce -33.2%
ELEV Elevation Oncology Inc. 0.01% 473,503 $284K Reduce -80.9%
Other holdings (16): bonds, preferreds, convertibles and warrants · $1.2B (not counted above)
SecurityClassShares / PrincipalValueChange
GUARDANT HEALTH INC (GH 0 11/15/27) NOTE 11/1 · principal 268,252,000$216.0MNo change
BRIDGEBIO PHARMA INC (BBIO 2.5 03/15/27) NOTE 2.500% 3/1 · principal 140,838,000$145.6MNo change
NOVOCURE LTD (NVCR 0 11/01/25) NOTE 11/0 · principal 140,834,000$133.3MNo change
NUVASIVE INC (GMED 0.375 03/15/25) NOTE 0.375% 3/1 · principal 114,206,000$111.9MNo change
NEOGENOMICS INC (NEO 0.25 01/15/28) NOTE 0.250% 1/1 · principal 116,381,000$96.9MNo change
IRONWOOD PHARMACEUTICALS (IRWD 1.5 06/15/26) NOTE 1.500% 6/1 · principal 92,740,000$82.5MAdd +3.3%
DEXCOM INC (DXCM 0.375 05/15/28) NOTE 0.375% 5/1 · principal 92,700,000$82.3MAdd +12.1%
INSULET CORPORATION (PODD 0.375 09/01/26) NOTE 0.375% 9/0 · principal 63,800,000$76.4MReduce -6.2%
DEXCOM INC (DXCM 0.25 11/15/25) NOTE 0.250%11/1 · principal 73,500,000$70.1MNo change
TRAVERE THERAPEUTICS INC (TVTX 2.5 09/15/25) NOTE 2.500% 9/1 · principal 56,031,000$53.5MNo change
ALPHATEC HOLDINGS INC (ATEC 0.75 08/01/26) NOTE 0.750% 8/0 · principal 58,217,000$52.5MNo change
BRIDGEBIO PHARMA INC (BBIO 2.25 02/01/29) NOTE 2.250% 2/0 · principal 53,594,000$45.0MReduce -18.3%
AMPHASTAR PHARMACEUTICAL (AMPH 2 03/15/29) NOTE 2.000% 3/1 · principal 18,400,000$19.5MNew
HAEMONETICS CORP (HAE 0 03/01/26) NOTE 3/0 · principal 11,500,000$10.6MNo change
CUTERA INC (CUTR 4 06/01/29) NOTE 4.000% 6/0 · principal 29,000,000$5.0MNo change
CUTERA INC (CUTR 2.25 06/01/28) NOTE 2.250% 6/0 · principal 25,240,000$4.0MNo change

Total filed on the 13F, all lines: $3.5B.

Portfolio Sells Q2 2024 → Q3 2024

TMO Thermo Fisher Scientific Inc. Sold out 0.00% −1.99
PCVX Vaxcyte Inc. Reduce -63.2% 1.46% −1.66
EXAS Exact Sciences Corp. Reduce -74.9% 0.84% −1.63
TMDX Transmedics Group Inc. Sold out 0.00% −1.46
ARGX Argenx SE - ADR Reduce -42.1% 2.26% −1.42
IMCR Immunocore Holdings PLC-ADR Sold out 0.00% −1.38
AKRO Akero Therapeutics Inc. Sold out 0.00% −1.30
GKOS Glaukos Corp. Reduce -37.3% 1.75% −1.26
LXEO Lexeo Therapeutics Inc. Reduce -47.3% 0.28% −0.85
APGE Apogee Therapeutics Inc. Reduce -31.3% 4.16% −0.66
LXRX Lexicon Pharmaceuticals Inc. Reduce -90.3% 0.05% −0.66
LEGN Legend Biotech Corp.-ADR Reduce -7.7% 3.23% −0.55
KROS Keros Therapeutics Inc. Reduce -28.0% 1.77% −0.53
IOVA Iovance Biotherapeutics Inc. Reduce -85.1% 0.09% −0.51
LIVN Livanova PLC Sold out 0.00% −0.49
INSP Inspire Medical Systems Inc. Reduce -37.0% 2.17% −0.43
ISRG Intuitive Surgical Inc. Reduce -9.2% 1.93% −0.36
ELEV Elevation Oncology Inc. Reduce -80.9% 0.01% −0.33
MRVI Maravai Lifesciences Hldgs-A Reduce -7.4% 2.99% −0.32
LBPH Longboard Pharmaceuticals Inc. Sold out 0.00% −0.28
FNA Paragon 28 Inc. Reduce -0.4% 1.19% −0.26
SYRE Spyre Therapeutics Inc. Reduce -12.9% 2.77% −0.25
SKIN Skinhealth Systems Inc. Reduce -20.9% 0.25% −0.25
CGON CG Oncology Inc. Reduce -4.2% 5.15% −0.20
OM Outset Medical Inc. Sold out 0.00% −0.14
BBIO Bridgebio Pharma Inc. Reduce -13.7% 0.33% −0.12
ALEC Alector Inc. Reduce -9.3% 0.43% −0.12
ETNB 89BIO Inc. Sold out 0.00% −0.07
CSTL Castle Biosciences Inc. Reduce -20.2% 0.41% −0.06
DBV TECHNOLOGIES S A Reduce -33.2% 0.05% −0.05

Portfolio Buys Q2 2024 → Q3 2024

APLS Apellis Pharmaceuticals Inc. Add +410.8% 3.88% +2.68
EWTX Edgewise Therapeutics Inc. New 2.25% +2.25
BCAX Bicara Therapeutics Inc. New 1.82% +1.82
MDGL Madrigal Pharmaceuticals Inc. New 1.68% +1.68
SRPT Sarepta Therapeutics Inc. Add +352.3% 1.99% +1.33
DXCM Dexcom Inc. New 1.27% +1.27
BNTX Biontech SE-ADR New 1.27% +1.27
KNSA Kiniksa Pharmaceuticals Inte Add +40.6% 3.11% +1.15
PEN Penumbra Inc. Add +70.0% 3.02% +1.07
REPL Replimune Group Inc. Add +203.0% 1.45% +0.98
IMTX Immatics NV New 0.81% +0.81
DAWN Day One Biopharmaceuticals I Add +60.5% 2.92% +0.78
CGEM Cullinan Therapeutics Inc. Add +567.6% 0.85% +0.69
BSX Boston Scientific Corp. New 0.68% +0.68
ARVN Arvinas Inc. Add +148.3% 1.36% +0.66
ORKA Oruka Therapeutics Inc. New 0.54% +0.54
HROW Harrow Inc. Add +47.9% 0.85% +0.53
RGEN Repligen Corp. Add +22.6% 2.54% +0.45
ZURA Zura Bio Ltd. New 0.43% +0.43
PODD Insulet Corp. New 0.43% +0.43
XNCR Xencor Inc. New 0.40% +0.40
JSPR Jasper Therapeutics Inc. New 0.39% +0.39
KRYS Krystal Biotech Inc. Add +57.4% 1.32% +0.31
OCUL Ocular Therapeutix Inc. Add +36.3% 0.84% +0.26
FDMT 4D Molecular Therapeutics Inc. Add +231.7% 0.57% +0.17
FULC Fulcrum Therapeutics Inc. New 0.16% +0.16
VKTX Viking Therapeutics Inc. Add +4.5% 3.15% +0.15
CELC Celcuity Inc. Add +71.2% 0.57% +0.13
VERV Verve Therapeutics Inc. New 0.13% +0.13
DNTH Dianthus Therapeutics Inc. Add +34.6% 0.58% +0.10
HLVX Hillevax Inc. New 0.08% +0.08
RLAY Relay Therapeutics Inc. Add +16.4% 1.07% +0.06
ALGN Align Technology Inc. Add +13.3% 3.41% +0.01
AVDL Avadel Pharmaceuticals Ltd. Add +16.9% 1.91% −0.17
ATEC Alphatec Holdings Inc. Add +84.1% 0.97% −0.21
IRTC Irhythm Holdings Inc. Add +48.7% 2.50% −0.40
XENE Xenon Pharmaceuticals Inc. Add +5.7% 4.59% −0.52
NBIX Neurocrine Biosciences Inc. Add +20.9% 4.55% −0.80
GH Guardant Health Inc. Add +19.0% 3.30% −0.85

Notes & Other Activity Q2 2024 → Q3 2024

IRONWOOD PHARMACEUTICALS (IRWD 1.5 06/15/26) NOTE 1.500% 6/1 · principal Add +3.3% 92,740,000 $82.5M
DEXCOM INC (DXCM 0.375 05/15/28) NOTE 0.375% 5/1 · principal Add +12.1% 92,700,000 $82.3M
INSULET CORPORATION (PODD 0.375 09/01/26) NOTE 0.375% 9/0 · principal Reduce -6.2% 63,800,000 $76.4M
SAREPTA THERAPEUTICS INC (SRPT 1.25 09/15/27) NOTE 1.250% 9/1 · principal Sold out 43,066,000 $55.5Mbefore exit
BRIDGEBIO PHARMA INC (BBIO 2.25 02/01/29) NOTE 2.250% 2/0 · principal Reduce -18.3% 53,594,000 $45.0M
AMPHASTAR PHARMACEUTICAL (AMPH 2 03/15/29) NOTE 2.000% 3/1 · principal New 18,400,000 $19.5M
CONMED CORP (CNMD 2.25 06/15/27) NOTE 2.250% 6/1 · principal Sold out 5,000,000 $4.5Mbefore exit

Bonds, preferreds, convertibles and warrants; not part of the stock holdings or percentages above.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 83$2.6BCAI, HNGE, GKOS, EWTX, SYRE
Q1 2026 82$2.6BCAI, NBIX, GKOS, CNTA, XENE
Q4 2025 68$2.6BCAI, EWTX, NBIX, GKOS, NUVL
Q3 2025 64$2.5BCAI, XENE, CGON, NBIX, KRYS
Q2 2025 45$2.1BCAI, NBIX, XENE, ARGX, KRYS
Q1 2025 52$1.9BNBIX, LEGN, ARGX, XENE, ALGN
Q4 2024 59$2.2BNBIX, XENE, LEGN, CGON, GH
Q3 2024 65$2.3BCGON, XENE, NBIX, APGE, APLS
Q2 2024 58$2.0BNBIX, CGON, XENE, APGE, GH
Q1 2024 51$1.8BAPGE, NBIX, ARGX, PCVX, LEGN