Braidwell LP

In its 13F for Q1 2026 (holdings as of March 31, 2026, filed May 15, 2026), Braidwell LP reported 82 stock positions worth $2.6 billion. Its top holding was Caris Life Sciences (CAI) at 5.5% of the portfolio, followed by Neurocrine Biosciences (NBIX, 3.3%) and Glaukos (GKOS, 3.1%). Compared with Q4 2025, it opened 28 new positions, sold out of 14, added to 19 and reduced 31. The biggest buy was a new position in Guardant Health (GH) and the biggest sale an exit from Align Technology (ALGN).

Most Recent 13F
Q2 2026
Location
STAMFORD, CT
CIK
0001920938
Portfolio Value
$2.6B (Q1 2026)
SEC Filing
0001420506-26-001145 ↗ filed May 15, 2026

Holdings Value

0$1.0B$2.0B$3.0B Q1 2024: $1.8B Q1 2024 Q2 2024: $2.0B Q2 2024 Q3 2024: $2.3B Q3 2024 Q4 2024: $2.2B Q4 2024 Q1 2025: $1.9B Q1 2025 Q2 2025: $2.1B Q2 2025 Q3 2025: $2.5B Q3 2025 Q4 2025: $2.6B Q4 2025 Q1 2026: $2.6B $2.6B Q1 2026 Q2 2026: $2.6B Q2 2026

Holdings 82 stocks · $2.6B
CAI Caris Life Sciences Inc. 5.45% 8,009,447 $143.2M Add +2.5%
NBIX Neurocrine Biosciences Inc. 3.27% 652,121 $85.9M Reduce -13.2%
GKOS Glaukos Corp. 3.13% 763,505 $82.2M Reduce -17.2%
CNTA Centessa Pharmaceuticals Ltd. 3.01% 1,986,768 $78.9M Reduce -9.2%
XENE Xenon Pharmaceuticals Inc. 2.96% 1,338,452 $77.8M Reduce -26.7%
DNTH Dianthus Therapeutics Inc. 2.87% 899,364 $75.5M Reduce -29.4%
EWTX Edgewise Therapeutics Inc. 2.82% 2,347,583 $73.9M Reduce -55.0%
IRTC Irhythm Holdings Inc. 2.74% 610,192 $72.0M Add +180.8%
NUVL Nuvalent Inc. Class A 2.73% 700,429 $71.8M Reduce -14.7%
KOD Kodiak Sciences Inc. 2.64% 1,818,665 $69.3M Reduce -12.3%
CGON CG Oncology Inc. 2.54% 984,783 $66.7M Reduce -47.4%
ARGX Argenx SE - ADR 2.36% 84,939 $62.0M Add +173.9%
HNGE Hinge Health Inc. Class A 2.14% 1,455,123 $56.1M Add +11.5%
ACAD Acadia Pharmaceuticals Inc. 2.10% 2,471,199 $55.0M Add +21.6%
GLUE Monte Rosa Therapeutics Inc. 2.01% 3,206,574 $52.7M Add +238.1%
KRYS Krystal Biotech Inc. 1.79% 182,425 $47.1M Reduce -9.7%
SYRE Spyre Therapeutics Inc. 1.79% 932,823 $47.1M Reduce -42.9%
GH Guardant Health Inc. 1.76% 499,712 $46.2M New
TMO Thermo Fisher Scientific Inc. 1.74% 92,915 $45.7M Add +15.1%
GENB Generate Biomedicines Inc. 1.71% 3,592,999 $44.9M New
MBX MBX Biosciences Inc. 1.70% 1,492,467 $44.6M Add +46.5%
BTSG Brightspring Health Services 1.65% 1,016,562 $43.3M Reduce -15.0%
CLDX Celldex Therapeutics Inc. 1.64% 1,356,082 $43.0M Reduce -27.0%
NEO Neogenomics Inc. 1.59% 5,617,402 $41.7M Add +21.3%
APGE Apogee Therapeutics Inc. 1.53% 478,667 $40.3M Reduce -16.8%
DRUG Bright Minds Biosciences Inc. 1.50% 539,708 $39.4M Add +66.4%
CDNA Caredx Inc. 1.44% 2,173,146 $37.7M Add +37.1%
ISRG Intuitive Surgical Inc. 1.36% 77,297 $35.6M Reduce -7.3%
INSP Inspire Medical Systems Inc. 1.33% 677,570 $34.9M Add +25.3%
PEN Penumbra Inc. 1.32% 105,352 $34.6M Reduce -4.4%
TMDX Transmedics Group Inc. 1.25% 329,391 $32.7M Add +4.5%
SLNO Soleno Therapeutics Inc. 1.22% 959,259 $32.1M Reduce -19.2%
DYN Dyne Therapeutics Inc. 1.16% 1,681,998 $30.5M Add +13.8%
MRVI Maravai Lifesciences Hldgs-A 1.10% 10,240,164 $29.0M Add +22.6%
ILMN Illumina Inc. 1.08% 229,215 $28.3M Reduce -15.0%
KYMR Kymera Therapeutics Inc. 1.07% 337,559 $28.1M Reduce -25.7%
BMRN Biomarin Pharmaceutical Inc. 1.07% 497,020 $28.1M Reduce -17.4%
NRIX Nurix Therapeutics Inc. 1.03% 1,750,766 $27.1M Reduce -19.8%
RYTM Rhythm Pharmaceuticals Inc. 1.03% 310,628 $27.0M New
DHR Danaher Corp. 1.01% 139,327 $26.4M Add +17.9%
ESTA Establishment Labs Holdings 1.00% 463,600 $26.3M New
TECX Tectonic Therapeutic Inc. 1.00% 847,151 $26.2M Reduce -8.7%
NTRA Natera Inc. 0.98% 129,000 $25.8M Add +15.7%
CRVS Corvus Pharmaceuticals Inc. 0.98% 1,752,798 $25.6M New
FULC Fulcrum Therapeutics Inc. 0.92% 3,134,922 $24.0M Add +2.4%
ZURA Zura Bio Ltd. 0.90% 3,988,989 $23.7M Add +25.4%
ATEC Alphatec Holdings Inc. 0.90% 2,172,725 $23.6M New
DMRA Damora Therapeutics Inc. 0.88% 894,846 $23.2M New
BSX Boston Scientific Corp. 0.83% 346,467 $21.7M New
VERA Vera Therapeutics Inc. 0.80% 523,824 $21.1M Reduce -33.3%
BIOA Bioage Labs Inc. 0.80% 1,200,587 $21.0M New
CVS CVS Health Corp. 0.80% 290,700 $20.9M Reduce -48.5%
TARS Tarsus Pharmaceuticals Inc. 0.71% 265,715 $18.6M New
ELV Elevance Health Inc. 0.69% 62,080 $18.2M New
KIDS Orthopediatrics Corp. 0.67% 1,100,370 $17.5M No change
ENGN Engene Holdings Inc. 0.64% 2,456,870 $16.7M Reduce -21.5%
NKTR Nektar Therapeutics 0.61% 222,701 $16.0M New
ACHC Acadia Healthcare Co. Inc. 0.58% 645,900 $15.1M New
ORIC Oric Pharmaceuticals Inc. 0.54% 1,128,040 $14.3M New
AVAH Aveanna Healthcare Holdings 0.54% 2,203,506 $14.2M New
XFOR X4 Pharmaceuticals Inc. 0.51% 3,272,954 $13.5M Reduce -2.9%
KNSA Kiniksa Pharmaceuticals Inte 0.50% 272,522 $13.1M Reduce -13.2%
EOLS Evolus Inc. 0.49% 3,105,209 $12.8M No change
TGTX TG Therapeutics Inc. 0.45% 358,800 $11.9M New
SRZN Surrozen Inc. 0.44% 396,100 $11.5M Reduce -15.7%
CNC Centene Corp. 0.41% 330,000 $10.8M New
CLYM Climb Bio Inc. 0.40% 1,529,675 $10.5M New
CMPX Compass Therapeutics Inc. 0.40% 1,965,106 $10.4M Reduce -29.5%
IONS Ionis Pharmaceuticals Inc. 0.37% 130,862 $9.8M New
HLXC Helix Acquisition Corp. Class A 0.35% 900,000 $9.3M New
VOR Vor Biopharma Inc. 0.32% 466,774 $8.3M New
RVMD Revolution Medicines Inc. 0.31% 84,900 $8.3M New
GRAL Grail Inc. 0.28% 142,755 $7.4M No change
ACRS Aclaris Therapeutics Inc. 0.24% 1,699,116 $6.4M New
DNLI Denali Therapeutics Inc. 0.22% 296,324 $5.7M New
RGEN Repligen Corp. 0.21% 47,500 $5.6M Reduce -41.9%
HROW Harrow Inc. 0.21% 156,419 $5.5M Reduce -47.0%
RVTY Revvity Inc. 0.16% 48,400 $4.2M New
CELC Celcuity Inc. 0.13% 29,198 $3.3M New
PRAX Praxis Precision Medicines I 0.12% 9,976 $3.2M New
LUNG Pulmonx Corp. 0.04% 752,541 $971K No change
VYNE THERAPEUTICS INC 0.02% 916,077 $547K New
Other holdings (6): bonds, preferreds, convertibles and warrants · $372.3M (not counted above)
SecurityClassShares / PrincipalValueChange
GUARDANT HEALTH INC (GH 1.25 02/15/31) DEBT 1.250% 2/1 · principal 60,954,000$102.6MReduce -41.9%
REPLIGEN CORP (RGEN 1 12/15/28) NOTE 1.000%12/1 · principal 101,000,000$98.7MNo change
NEOGENOMICS INC (NEO 0.25 01/15/28) NOTE 0.250% 1/1 · principal 100,381,000$91.8MNo change
ALPHATEC HOLDINGS INC (ATEC 0.75 03/15/30) NOTE 0.750% 3/1 · principal 61,621,000$63.4MNew
ZENAS BIOPHARMA INC (ZBIO 2.5 04/01/32) NOTE 2.500% 4/0 · principal 13,000,000$13.5MNew
ARROWHEAD RESEARCH CORP (ARWR 0 01/15/32) NOTE 1/1 · principal 2,250,000$2.3MNew

Total filed on the 13F, all lines: $3.0B.

Portfolio Sells Q4 2025 → Q1 2026
ALGN Align Technology Inc. Sold out 0.00% −2.28
EWTX Edgewise Therapeutics Inc. Reduce -55.0% 2.82% −2.14
RAPT Rapt Therapeutics Inc. Sold out 0.00% −1.21
LEGN Legend Biotech Corp.-ADR Sold out 0.00% −1.08
CVS CVS Health Corp. Reduce -48.5% 0.80% −0.92
TERN Terns Pharmaceuticals Inc. Sold out 0.00% −0.89
SLNO Soleno Therapeutics Inc. Reduce -19.2% 1.22% −0.88
GKOS Glaukos Corp. Reduce -17.2% 3.13% −0.86
NBIX Neurocrine Biosciences Inc. Reduce -13.2% 3.27% −0.81
BIIB Biogen Inc. Sold out 0.00% −0.78
VERA Vera Therapeutics Inc. Reduce -33.3% 0.80% −0.72
VTYX Ventyx Biosciences Inc. Sold out 0.00% −0.66
NRIX Nurix Therapeutics Inc. Reduce -19.8% 1.03% −0.55
ICLR Icon PLC Sold out 0.00% −0.51
ISRG Intuitive Surgical Inc. Reduce -7.3% 1.36% −0.45
ENGN Engene Holdings Inc. Reduce -21.5% 0.64% −0.45
CGON CG Oncology Inc. Reduce -47.4% 2.54% −0.44
NUVL Nuvalent Inc. Class A Reduce -14.7% 2.73% −0.43
HROW Harrow Inc. Reduce -47.0% 0.21% −0.34
RGEN Repligen Corp. Reduce -41.9% 0.21% −0.30
BMRN Biomarin Pharmaceutical Inc. Reduce -17.4% 1.07% −0.30
CLDX Celldex Therapeutics Inc. Reduce -27.0% 1.64% −0.29
RLMD Relmada Therapeutics Inc. Sold out 0.00% −0.29
KYMR Kymera Therapeutics Inc. Reduce -25.7% 1.07% −0.28
ILMN Illumina Inc. Reduce -15.0% 1.08% −0.28
XNCR Xencor Inc. Sold out 0.00% −0.27
CSTL Castle Biosciences Inc. Sold out 0.00% −0.26
SYRE Spyre Therapeutics Inc. Reduce -42.9% 1.79% −0.26
ADPT Adaptive Biotechnologies Sold out 0.00% −0.19
CMPX Compass Therapeutics Inc. Reduce -29.5% 0.40% −0.18
XENE Xenon Pharmaceuticals Inc. Reduce -26.7% 2.96% −0.17
BLLN Billiontoone Inc. Class A Sold out 0.00% −0.16
APGE Apogee Therapeutics Inc. Reduce -16.8% 1.53% −0.13
KRYS Krystal Biotech Inc. Reduce -9.7% 1.79% −0.11
ORKA Oruka Therapeutics Inc. Sold out 0.00% −0.10
KPTI Karyopharm Therapeutics Inc. Sold out 0.00% −0.09
BTSG Brightspring Health Services Reduce -15.0% 1.65% −0.07
XFOR X4 Pharmaceuticals Inc. Reduce -2.9% 0.51% −0.00
KNSA Kiniksa Pharmaceuticals Inte Reduce -13.2% 0.50% +0.00
PEN Penumbra Inc. Reduce -4.4% 1.32% +0.01
SRZN Surrozen Inc. Reduce -15.7% 0.44% +0.03
TECX Tectonic Therapeutic Inc. Reduce -8.7% 1.00% +0.26
KOD Kodiak Sciences Inc. Reduce -12.3% 2.64% +0.42
DNTH Dianthus Therapeutics Inc. Reduce -29.4% 2.87% +0.86
CNTA Centessa Pharmaceuticals Ltd. Reduce -9.2% 3.01% +0.91

Portfolio Buys Q4 2025 → Q1 2026
GH Guardant Health Inc. New 1.76% +1.76
GENB Generate Biomedicines Inc. New 1.71% +1.71
GLUE Monte Rosa Therapeutics Inc. Add +238.1% 2.01% +1.44
ARGX Argenx SE - ADR Add +173.9% 2.36% +1.36
IRTC Irhythm Holdings Inc. Add +180.8% 2.74% +1.27
RYTM Rhythm Pharmaceuticals Inc. New 1.03% +1.03
ESTA Establishment Labs Holdings New 1.00% +1.00
CRVS Corvus Pharmaceuticals Inc. New 0.98% +0.98
ATEC Alphatec Holdings Inc. New 0.90% +0.90
DMRA Damora Therapeutics Inc. New 0.88% +0.88
BSX Boston Scientific Corp. New 0.83% +0.83
BIOA Bioage Labs Inc. New 0.80% +0.80
TARS Tarsus Pharmaceuticals Inc. New 0.71% +0.71
ELV Elevance Health Inc. New 0.69% +0.69
NKTR Nektar Therapeutics New 0.61% +0.61
ACHC Acadia Healthcare Co. Inc. New 0.58% +0.58
ORIC Oric Pharmaceuticals Inc. New 0.54% +0.54
AVAH Aveanna Healthcare Holdings New 0.54% +0.54
DRUG Bright Minds Biosciences Inc. Add +66.4% 1.50% +0.53
MBX MBX Biosciences Inc. Add +46.5% 1.70% +0.47
TGTX TG Therapeutics Inc. New 0.45% +0.45
CNC Centene Corp. New 0.41% +0.41
CLYM Climb Bio Inc. New 0.40% +0.40
IONS Ionis Pharmaceuticals Inc. New 0.37% +0.37
HLXC Helix Acquisition Corp. Class A New 0.35% +0.35
VOR Vor Biopharma Inc. New 0.32% +0.32
RVMD Revolution Medicines Inc. New 0.31% +0.31
CDNA Caredx Inc. Add +37.1% 1.44% +0.29
ZURA Zura Bio Ltd. Add +25.4% 0.90% +0.27
ACRS Aclaris Therapeutics Inc. New 0.24% +0.24
DNLI Denali Therapeutics Inc. New 0.22% +0.22
RVTY Revvity Inc. New 0.16% +0.16
CELC Celcuity Inc. New 0.13% +0.13
PRAX Praxis Precision Medicines I New 0.12% +0.12
MRVI Maravai Lifesciences Hldgs-A Add +22.6% 1.10% +0.06
DYN Dyne Therapeutics Inc. Add +13.8% 1.16% +0.05
VYNE THERAPEUTICS INC New 0.02% +0.02
ACAD Acadia Pharmaceuticals Inc. Add +21.6% 2.10% +0.02
NTRA Natera Inc. Add +15.7% 0.98% +0.00
DHR Danaher Corp. Add +17.9% 1.01% −0.03
TMO Thermo Fisher Scientific Inc. Add +15.1% 1.74% −0.05
HNGE Hinge Health Inc. Class A Add +11.5% 2.14% −0.18
TMDX Transmedics Group Inc. Add +4.5% 1.25% −0.22
FULC Fulcrum Therapeutics Inc. Add +2.4% 0.92% −0.41
NEO Neogenomics Inc. Add +21.3% 1.59% −0.50
INSP Inspire Medical Systems Inc. Add +25.3% 1.33% −0.58
CAI Caris Life Sciences Inc. Add +2.5% 5.45% −2.62

Notes & Other Activity Q4 2025 → Q1 2026
GUARDANT HEALTH INC (GH 1.25 02/15/31) DEBT 1.250% 2/1 · principal Reduce -41.9% 60,954,000 $102.6M
IRHYTHM HOLDINGS INC (IRTC 1.5 09/01/29) NOTE 1.500% 9/0 · principal Sold out 52,000,000 $72.8Mbefore exit
ALPHATEC HOLDINGS INC (ATEC 0.75 03/15/30) NOTE 0.750% 3/1 · principal New 61,621,000 $63.4M
IRONWOOD PHARMACEUTICALS (IRWD 1.5 06/15/26) NOTE 1.500% 6/1 · principal Sold out 53,405,000 $50.5Mbefore exit
ZENAS BIOPHARMA INC (ZBIO 2.5 04/01/32) NOTE 2.500% 4/0 · principal New 13,000,000 $13.5M
ARROWHEAD RESEARCH CORP (ARWR 0 01/15/32) NOTE 1/1 · principal New 2,250,000 $2.3M

Bonds, preferreds, convertibles and warrants; not part of the stock holdings or percentages above.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 83$2.6BCAI, HNGE, GKOS, EWTX, SYRE
Q1 2026 82$2.6BCAI, NBIX, GKOS, CNTA, XENE
Q4 2025 68$2.6BCAI, EWTX, NBIX, GKOS, NUVL
Q3 2025 64$2.5BCAI, XENE, CGON, NBIX, KRYS
Q2 2025 45$2.1BCAI, NBIX, XENE, ARGX, KRYS
Q1 2025 52$1.9BNBIX, LEGN, ARGX, XENE, ALGN
Q4 2024 59$2.2BNBIX, XENE, LEGN, CGON, GH
Q3 2024 65$2.3BCGON, XENE, NBIX, APGE, APLS
Q2 2024 58$2.0BNBIX, CGON, XENE, APGE, GH
Q1 2024 51$1.8BAPGE, NBIX, ARGX, PCVX, LEGN