Driehaus Capital Management LLC

In its 13F for Q4 2025 (holdings as of December 31, 2025, filed February 17, 2026), Driehaus Capital Management LLC reported 385 stock positions worth $14.7 billion. Its top holding was Taiwan Semiconductor-SP ADR (TSM) at 4.5% of the portfolio, followed by Crinetics Pharmaceuticals (CRNX, 2.0%) and Praxis Precision Medicines I (PRAX, 1.9%). Compared with Q3 2025, it opened 77 new positions, sold out of 110, added to 135 and reduced 150. The biggest buy was Praxis Precision Medicines I (PRAX, shares +86%) and the biggest sale Astera Labs (ALAB, shares −100%).

Most Recent 13F
Q2 2026
Location
Chicago, IL
CIK
0000938206
Portfolio Value
$14.7B (Q4 2025)
SEC Filing
0000938206-26-000018 ↗ filed Feb 17, 2026

Holdings Value

0$5.0B$10.0B$15.0B$20.0B Q1 2024: $10.0B Q1 2024 Q2 2024: $10.3B Q2 2024 Q3 2024: $11.6B Q3 2024 Q4 2024: $12.1B Q4 2024 Q1 2025: $10.4B Q1 2025 Q2 2025: $12.5B Q2 2025 Q3 2025: $14.0B Q3 2025 Q4 2025: $14.7B $14.7B Q4 2025 Q1 2026: $13.6B Q1 2026 Q2 2026: $17.3B Q2 2026

Holdings 385 stocks · $14.7B

TSM Taiwan Semiconductor-SP ADR 4.47% 2,163,564 $657.5M Reduce -3.6%
CRNX Crinetics Pharmaceuticals Inc. 2.02% 6,387,740 $297.3M Reduce -1.4%
PRAX Praxis Precision Medicines I 1.87% 933,061 $275.0M Add +86.4%
GH Guardant Health Inc. 1.49% 2,143,193 $218.9M Reduce -0.4%
XENE Xenon Pharmaceuticals Inc. 1.38% 4,538,691 $203.4M Add +8.9%
PL Planet Labs PBC 1.14% 8,511,620 $167.8M Reduce -40.8%
APGE Apogee Therapeutics Inc. 1.12% 2,183,704 $164.8M Add +1.2%
EOSE Eos Energy Enterprises Inc. 1.11% 14,270,294 $163.5M Add +117.3%
SITM Sitime Corp. 0.99% 412,873 $145.8M Reduce -28.2%
NTRA Natera Inc. 0.97% 625,912 $143.4M Add +6.8%
CCJ Cameco Corp. 0.95% 1,522,638 $139.3M Reduce -12.9%
FTAI Ftai Aviation Ltd. 0.94% 700,525 $137.9M Add +6.9%
RYTM Rhythm Pharmaceuticals Inc. 0.93% 1,285,222 $137.6M Reduce -7.1%
HDB HDFC Bank Ltd.-ADR 0.92% 3,722,331 $136.0M Add +16.1%
BAP Credicorp Ltd. 0.92% 472,044 $135.5M Add +6.8%
SEPN Septerna Inc. 0.91% 4,809,470 $134.1M Reduce -2.2%
NU Nu Holdings Ltd./Cayman Isl-A filed as NU HLDGS LTD 0.88% 7,706,057 $129.0M Add +91.8%
BBIO Bridgebio Pharma Inc. 0.87% 1,680,972 $128.6M Add +1.1%
PI Impinj Inc. 0.87% 737,474 $128.3M Add +43.3%
CRS Carpenter Technology 0.86% 403,296 $127.0M Add +47.2%
CW Curtiss-Wright Corp. 0.86% 229,703 $126.6M Reduce -14.6%
LITE Lumentum Holdings Inc. 0.85% 341,048 $125.7M Reduce -43.8%
IBN Icici Bank Ltd.-Spon ADR 0.82% 4,063,452 $121.1M Reduce -24.2%
IDCC Interdigital Inc. 0.81% 375,174 $119.4M Add +13.6%
XMTR Xometry Inc. Class A 0.80% 1,985,865 $118.1M Add +32.6%
ARWR Arrowhead Pharmaceuticals Inc. 0.80% 1,769,340 $117.5M Reduce -15.7%
GPCR Structure Therapeutics Inc. 0.78% 1,642,444 $114.2M Add +88.0%
WVE Wave Life Sciences Ltd. 0.76% 6,581,067 $111.9M Add +4.5%
FN Fabrinet 0.75% 240,978 $109.7M Reduce -35.5%
WFRD Weatherford International PL 0.74% 1,384,142 $108.3M Add +43.6%
UEC Uranium Energy Corp. 0.72% 9,112,072 $106.4M Reduce -4.0%
EWTX Edgewise Therapeutics Inc. 0.71% 4,191,193 $104.0M Add +88.1%
EMBJ Embraer SA-Spon ADR 0.70% 1,590,028 $102.4M Add +71.2%
KRMN Karman Holdings Inc. 0.67% 1,355,169 $99.2M Reduce -12.8%
PTGX Protagonist Therapeutics Inc. 0.65% 1,099,170 $96.0M Reduce -3.6%
TARS Tarsus Pharmaceuticals Inc. 0.65% 1,172,427 $96.0M Add +13.7%
CVNA Carvana Co. 0.65% 226,963 $95.8M Reduce -28.6%
SYRE Spyre Therapeutics Inc. 0.64% 2,882,420 $94.4M Add +39.9%
CR Crane Co. 0.63% 505,668 $93.3M Reduce -6.1%
EYE National Vision Holdings Inc. 0.63% 3,606,811 $93.1M Add +59.9%
VSEC Vse Corp. 0.61% 520,237 $89.9M Add +54.1%
RMBS Rambus Inc. 0.60% 954,164 $87.7M New
DFTX Definium Therapeutics Inc. 0.59% 6,537,202 $87.5M New
TMDX Transmedics Group Inc. 0.59% 712,041 $86.6M Reduce -3.5%
PTCT PTC Therapeutics Inc. 0.59% 1,136,188 $86.3M Add +0.4%
SRRK Scholar Rock Holding Corp. 0.58% 1,952,877 $86.0M Reduce -3.5%
SPXC SPX Technologies Inc. 0.58% 429,764 $86.0M Add +56.1%
ITUB Itau Unibanco H-Spon PRF ADR 0.58% 11,857,114 $84.9M Add +12.0%
KYMR Kymera Therapeutics Inc. 0.57% 1,069,238 $83.2M Add +13.9%
COHR Coherent Corp. 0.56% 447,945 $82.7M Add +2.1%
MTSI Macom Technology Solutions H 0.56% 482,051 $82.6M Add +28.6%
CPA Copa Holdings SA Class A 0.55% 670,657 $80.9M Add +2.5%
IMNM Immunome Inc. 0.54% 3,705,974 $79.6M Add +432.1%
AXON Axon Enterprise Inc. 0.53% 136,364 $77.4M Reduce -17.4%
AVAV Aerovironment Inc. 0.53% 319,833 $77.4M Reduce -4.3%
TCOM Trip.com Group Ltd.-ADR 0.52% 1,072,741 $77.1M Add +5.0%
RSI Rush Street Interactive Inc. 0.51% 3,889,159 $75.6M Reduce -3.6%
VALE Vale SA-SP ADR 0.51% 5,780,150 $75.3M Reduce -29.4%
ROAD Construction Partners Inc. Class A 0.51% 693,594 $75.3M Reduce -22.4%
REAL The Realreal Inc. filed as THE REALREAL INC 0.51% 4,754,440 $75.0M Add +53.6%
ARQT Arcutis Biotherapeutics Inc. 0.51% 2,562,445 $74.4M Add +133.6%
INDV Indivior Pharmaceuticals Inc. 0.49% 2,000,339 $71.8M New
PAY Paymentus Holdings Inc. Class A 0.48% 2,239,138 $70.7M Reduce -9.3%
SCCO Southern Copper Corp. 0.47% 486,393 $69.8M Reduce -35.0%
NXT Nextpower Inc. 0.47% 799,738 $69.7M Add +74.4%
SMTC Semtech Corp. 0.47% 931,305 $68.6M Add +108.3%
FMX Fomento Economico Mex-SP ADR 0.46% 672,848 $68.0M New
FLS Flowserve Corp. 0.46% 977,589 $67.8M Reduce -8.0%
WULF Terawulf Inc. 0.46% 5,864,195 $67.4M Reduce -34.9%
GGAL Grupo Financiero Galicia-ADR 0.45% 1,236,833 $66.7M Add +31.5%
HAPN Happen Inc. filed as LENDINGCLUB CORP 0.45% 3,519,350 $66.7M Reduce -3.5%
HCI Hci Group Inc. 0.45% 346,329 $66.4M Reduce -19.6%
MDGL Madrigal Pharmaceuticals Inc. 0.44% 111,666 $65.0M Reduce -3.7%
ULS Ul Solutions Inc. Class A 0.44% 817,581 $64.5M Add +191.9%
MOD Modine Manufacturing Co. 0.44% 480,392 $64.1M Reduce -28.6%
BOOT Boot Barn Holdings Inc. 0.43% 360,278 $63.6M Reduce -23.9%
FTI Technipfmc PLC 0.42% 1,384,997 $61.7M Reduce -12.2%
PAAS Pan American Silver Corp. 0.42% 1,188,932 $61.6M Reduce -41.3%
ATEC Alphatec Holdings Inc. 0.41% 2,858,771 $60.1M Add +102.8%
OSIS Osi Systems Inc. 0.41% 235,768 $60.1M Add +60.3%
TNL Travel + Leisure Co. 0.41% 847,346 $59.8M Add +52.2%
STRL Sterling Infrastructure Inc. 0.40% 194,539 $59.6M Reduce -45.6%
LEU Centrus Energy Corp. Class A 0.40% 244,344 $59.3M Reduce -32.0%
DAVE Dave Inc. 0.39% 257,437 $57.0M Reduce -16.1%
SEI Solaris Energy Infrastructur 0.38% 1,227,721 $56.4M Add +27.7%
CUBI Customers Bancorp Inc. 0.38% 766,207 $56.0M Add +79.8%
CRDO Credo Technology Group Holdi 0.38% 383,696 $55.2M Reduce -56.3%
ONTO Onto Innovation Inc. 0.37% 349,014 $55.1M Add +247.4%
GRAB Grab Holdings Ltd. Class A 0.37% 11,003,892 $54.9M Add +42.9%
IAG Iamgold Corp. 0.37% 3,274,437 $54.0M Add +13.4%
MIR Mirion Technologies Inc. 0.37% 2,299,122 $53.8M Add +15.7%
IBP Installed Building Products 0.37% 207,279 $53.8M Reduce -9.3%
COCO The Vita Coco Co. Inc. 0.37% 1,014,236 $53.8M Add +61.9%
ORA Ormat Technologies Inc. 0.36% 473,770 $52.3M Add +226.4%
TPB Turning Point Brands Inc. 0.35% 481,834 $52.2M Add +19.0%
PIPR Piper Sandler Cos 0.35% 152,006 $51.6M Add +86.5%
SQM Quimica Y Minera Chil-SP ADR filed as SOCIEDAD QUIMICA Y MINERA DE 0.35% 747,890 $51.5M New
WGS Genedx Holdings Corp. 0.35% 395,323 $51.4M Reduce -3.6%
ECG Everus Construction Group 0.35% 593,905 $50.8M Reduce -8.3%
MYRG MYR Group Inc./Delaware 0.34% 228,655 $50.0M Add +9.5%

Show all 385 holdings

Other holdings (19): bonds, preferreds, convertibles and warrants · $2.2M (not counted above)
SecurityClassShares / PrincipalValueChange
HYAC.WS Haymaker Acquisition Corp.-28 *W EXP 05/31/202 249,999$387KNo change
BEAGR Bold Eagle Acquisition Corp. RIGHT 10/11/2029 1,200,000$384KNew
ATIIW Archimedes Tech-30 *W EXP 10/15/202 400,000$220KNo change
KFIIR K&F Growth Acquisition Corp. RIGHT 08/29/2031 1,200,000$192KNo change
PGYWW Pagaya Technologies Ltd. -27 *W EXP 99/99/999 480,716$154KNo change
OACCW Oaktree Acquisition III -31 *W EXP 09/01/203 180,000$128KNo change
RVMDW Revolution Medicines Inc.-28 *W EXP 12/17/202 135,000$127KNo change
BAERW Wildfire New Pubco Inc.-27 *W EXP 01/24/202 620,220$124KNo change
NHICW Newhold Investment Corp. - 30 *W EXP 01/30/203 249,999$90KNo change
TACOW Berto Acquisition Corp. - 30 *W EXP 05/01/203 226,724$84KNo change
GSHRW Gesher Acquisition Corp. I-30 *W EXP 10/31/203 199,999$70KNo change
HVMCW Highview Merger Corp. - 30 *W EXP 07/24/203 250,000$68KNo change
DNMXW Dynamix Corp. III *W EXP 10/10/203 150,000$48KNew
APXTW Apex Treasury Corp. -30 *W EXP 10/07/203 125,000$35KNew
LATAW Galata Acquisition Corp. - 30 *W EXP 09/12/203 66,666$23KNo change
BDCIW BTC Development Corp. - 30 *W EXP 09/11/203 24,999$11KNo change
DYORW Insight Digital Partners II *W EXP 10/28/203 25,000$8KNew
HCMAW HCM III Acquisition Corp. -30 *W EXP 07/23/203 16,666$8KNew
ISPOW Inspirato -CW30 *W EXP 02/11/202 167,540$1KNo change

Total filed on the 13F, all lines: $14.7B.

Portfolio Sells Q3 2025 → Q4 2025

ALAB Astera Labs Inc. Reduce -99.7% 0.00% −1.15
CVLT Commvault Systems Inc. Sold out 0.00% −0.86
STNE Stoneco Ltd. Class A Reduce -79.5% 0.10% −0.58
OLLI Ollie's Bargain Outlet Holdi Sold out 0.00% −0.55
CRDO Credo Technology Group Holdi Reduce -56.3% 0.38% −0.54
MELI MercadoLibre Inc. Sold out 0.00% −0.51
CORZ Core Scientific Inc. Sold out 0.00% −0.51
TME Tencent Music Entertainm-ADR Sold out 0.00% −0.50
LOPE Grand Canyon Education Inc. Reduce -75.1% 0.11% −0.49
STRL Sterling Infrastructure Inc. Reduce -45.6% 0.40% −0.47
CVSA Covista Inc. Sold out 0.00% −0.46
SRAD Sportradar Group AG-A Sold out 0.00% −0.44
QBTS D-Wave Quantum Inc. Sold out 0.00% −0.43
AMSC American Superconductor Corp. Reduce -59.0% 0.10% −0.42
LRN Stride Inc. Sold out 0.00% −0.41
KTOS Kratos Defense & Security Reduce -59.4% 0.19% −0.41
LEU Centrus Energy Corp. Class A Reduce -32.0% 0.40% −0.40
RKLB Rocket Lab Corp. Reduce -76.6% 0.19% −0.39
VC Visteon Corp. Sold out 0.00% −0.37
BE Bloom Energy Corp. Class A Reduce -52.6% 0.30% −0.35
IBN Icici Bank Ltd.-Spon ADR Reduce -24.2% 0.82% −0.34
AXON Axon Enterprise Inc. Reduce -17.4% 0.53% −0.32
CORT Corcept Therapeutics Inc. Sold out 0.00% −0.31
ROAD Construction Partners Inc. Class A Reduce -22.4% 0.51% −0.30
RBRK Rubrik Inc. Class A Sold out 0.00% −0.30
ODD Oddity Tech Ltd. Class A Sold out 0.00% −0.30
OUST Ouster Inc. Sold out 0.00% −0.30
USAR USA Rare Earth Inc. Sold out 0.00% −0.28
GTES Gates Industrial Corp. UK Ltd. Sold out 0.00% −0.28
WULF Terawulf Inc. Reduce -34.9% 0.46% −0.28
WYFI Whitefiber Inc. Sold out 0.00% −0.27
MIND MEDICINE MINDMED INC Sold out 0.00% −0.26
SITM Sitime Corp. Reduce -28.2% 0.99% −0.25
MOD Modine Manufacturing Co. Reduce -28.6% 0.44% −0.25
HUT Hut 8 Corp. Reduce -82.8% 0.07% −0.25
LTH Life Time Group Holdings Inc. Reduce -70.8% 0.09% −0.24
CLS Celestica Inc. Reduce -49.8% 0.32% −0.24
ASTS Ast Spacemobile Inc. Reduce -76.0% 0.12% −0.24
MGNI Magnite Inc. Sold out 0.00% −0.24
SMR Nuscale Power Corp. Sold out 0.00% −0.24
KRRO Korro Bio Inc. Sold out 0.00% −0.23
FN Fabrinet Reduce -35.5% 0.75% −0.23
AVAV Aerovironment Inc. Reduce -4.3% 0.53% −0.23
VRNS Varonis Systems Inc. Sold out 0.00% −0.23
SKWD Skyward Specialty Insurance Sold out 0.00% −0.22
QFIN Qfin Holdings Inc.-ADR Sold out 0.00% −0.21
CVNA Carvana Co. Reduce -28.6% 0.65% −0.21
AGX Argan Inc. Reduce -81.8% 0.05% −0.20
PL Planet Labs PBC Reduce -40.8% 1.14% −0.20
WWW Wolverine World Wide Inc. Sold out 0.00% −0.20

Portfolio Buys Q3 2025 → Q4 2025

PRAX Praxis Precision Medicines I Add +86.4% 1.87% +1.68
GPCR Structure Therapeutics Inc. Add +88.0% 0.78% +0.60
RMBS Rambus Inc. New 0.60% +0.60
DFTX Definium Therapeutics Inc. New 0.59% +0.59
EOSE Eos Energy Enterprises Inc. Add +117.3% 1.11% +0.58
APGE Apogee Therapeutics Inc. Add +1.2% 1.12% +0.51
INDV Indivior Pharmaceuticals Inc. New 0.49% +0.49
IMNM Immunome Inc. Add +432.1% 0.54% +0.48
FMX Fomento Economico Mex-SP ADR New 0.46% +0.46
EWTX Edgewise Therapeutics Inc. Add +88.1% 0.71% +0.45
WVE Wave Life Sciences Ltd. Add +4.5% 0.76% +0.43
NU Nu Holdings Ltd./Cayman Isl-A Add +91.8% 0.88% +0.42
SYRE Spyre Therapeutics Inc. Add +39.9% 0.64% +0.39
CRS Carpenter Technology Add +47.2% 0.86% +0.38
ARQT Arcutis Biotherapeutics Inc. Add +133.6% 0.51% +0.36
SQM Quimica Y Minera Chil-SP ADR New 0.35% +0.35
SAIA Saia Inc. New 0.32% +0.32
ALH Alliance Laundry Holdings Inc. New 0.30% +0.30
NTRA Natera Inc. Add +6.8% 0.97% +0.30
ULS Ul Solutions Inc. Class A Add +191.9% 0.44% +0.30
GLOB Globant SA New 0.30% +0.30
EMBJ Embraer SA-Spon ADR Add +71.2% 0.70% +0.29
TER Teradyne Inc. New 0.29% +0.29
ONTO Onto Innovation Inc. Add +247.4% 0.37% +0.28
COMP Compass Inc. Class A New 0.28% +0.28
DOO BRP Inc./Ca- Sub Voting New 0.28% +0.28
REAL The Realreal Inc. Add +53.6% 0.51% +0.27
GGAL Grupo Financiero Galicia-ADR Add +31.5% 0.45% +0.27
WFRD Weatherford International PL Add +43.6% 0.74% +0.26
ATEC Alphatec Holdings Inc. Add +102.8% 0.41% +0.26
ORA Ormat Technologies Inc. Add +226.4% 0.36% +0.26
BBIO Bridgebio Pharma Inc. Add +1.1% 0.87% +0.26
SHOO Steven Madden Ltd. New 0.24% +0.24
TNDM Tandem Diabetes Care Inc. New 0.24% +0.24
SMTC Semtech Corp. Add +108.3% 0.47% +0.24
TTI Tetra Technologies Inc. New 0.24% +0.24
NXT Nextpower Inc. Add +74.4% 0.47% +0.23
MTSI Macom Technology Solutions H Add +28.6% 0.56% +0.23
VIST Vista Energy Sab DE CV Add +1123.3% 0.24% +0.22
COHR Coherent Corp. Add +2.1% 0.56% +0.22
VSXY Victoria's Secret & Co. New 0.22% +0.22
INSP Inspire Medical Systems Inc. New 0.22% +0.22
XMTR Xometry Inc. Class A Add +32.6% 0.80% +0.22
SPXC SPX Technologies Inc. Add +56.1% 0.58% +0.22
TARS Tarsus Pharmaceuticals Inc. Add +13.7% 0.65% +0.21
VSEC Vse Corp. Add +54.1% 0.61% +0.21
PI Impinj Inc. Add +43.3% 0.87% +0.21
LGN Legence Corp. Class A New 0.20% +0.20
NEO Neogenomics Inc. New 0.20% +0.20
NUVL Nuvalent Inc. Class A Add +123.3% 0.33% +0.20

Notes & Other Activity Q3 2025 → Q4 2025

BEAGR Bold Eagle Acquisition Corp. RIGHT 10/11/2029 New 1,200,000 $384K
XRPNW Armada Acquisition Corp - A *W EXP 05/21/203 Sold out 74,999 $71Kbefore exit
DNMXW Dynamix Corp. III *W EXP 10/10/203 New 150,000 $48K
APXTW Apex Treasury Corp. -30 *W EXP 10/07/203 New 125,000 $35K
BLUWW Blue Water Acquisition-CW26 *W EXP 05/23/203 Sold out 112,500 $16Kbefore exit
DYORW Insight Digital Partners II *W EXP 10/28/203 New 25,000 $8K
HCMAW HCM III Acquisition Corp. -30 *W EXP 07/23/203 New 16,666 $8K

Bonds, preferreds, convertibles and warrants; not part of the stock holdings or percentages above.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 353$17.3BTSM, DFTX, PRAX, XENE, SIMO
Q1 2026 354$13.6BTSM, PRAX, XENE, CRNX, PL
Q4 2025 385$14.7BTSM, CRNX, PRAX, GH, XENE
Q3 2025 418$14.0BTSM, CRNX, PL, SITM, XENE
Q2 2025 403$12.5BTSM, CCJ, IBN, AXON, CYBR
Q1 2025 388$10.4BTSM, IBN, CRNX, XENE, SFM
Q4 2024 375$12.1BTSM, CRNX, IBN, XENE, ALAB
Q3 2024 370$11.6BTSM, CRNX, TMDX, IBN, PCVX
Q2 2024Amended 361$10.3BTSM, CRNX, TMDX, CCJ, IBN
Q1 2024 380$10.0BTSM, SMCI, CRNX, XENE, CAMT