Knoll Capital Management, LLC

In its 13F for Q1 2024 (holdings as of March 31, 2024, filed May 15, 2024), Knoll Capital Management, LLC reported 34 stock positions worth $160.7 million. Its top holding was Applied Therapeutics (APLT) at 23.6% of the portfolio, followed by Biohaven Pharmaceutical Hold (16.7%) and Aldeyra Therapeutics (ALDX, 11.1%). Compared with Q4 2023, it opened 5 new positions, sold out of 3, added to 5 and reduced 1. The biggest buy was Applied Therapeutics (APLT, shares +2%) and the biggest sale Global X Silver Miners ETF (SIL, shares −74%).

Most Recent 13F
Q2 2026
Location
MIAMI, FL
CIK
0001325083
Portfolio Value
$160.7M (Q1 2024)
SEC Filing
0001104659-24-061904 ↗ filed May 15, 2024

Holdings Value

0$50.0M$100.0M$150.0M$200.0M$250.0M Q1 2024: $160.7M $160.7M Q1 2024 Q2 2024: $148.4M Q2 2024 Q3 2024: $215.8M Q3 2024 Q4 2024: $155.3M Q4 2024 Q1 2025: $153.7M Q1 2025 Q2 2025: $140.7M Q2 2025 Q3 2025: $186.6M Q3 2025 Q4 2025: $218.0M Q4 2025 Q1 2026: $188.7M Q1 2026 Q2 2026: $214.3M Q2 2026

Holdings 34 stocks · $160.7M
APLT Applied Therapeutics Inc. 23.58% 5,574,687 $37.9M Add +1.8%
BIOHAVEN PHARMACEUTICAL HOLD 16.69% 490,422 $26.8M No change
ALDX Aldeyra Therapeutics Inc. 11.14% 5,475,516 $17.9M No change
AVDL Avadel Pharmaceuticals plc 6.30% 600,000 $10.1M No change
GLD SPDR Gold Shares 4.10% 32,000 $6.6M New
ENTX Entera Bio Ltd. 4.03% 3,881,879 $6.5M No change
ALT Altimmune Inc. 3.59% 567,219 $5.8M Add +183.6%
HOOKIPA PHARMA INC 2.44% 5,517,385 $3.9M No change
SA Seabridge Gold Inc. 2.32% 246,597 $3.7M No change
EQX Equinox Gold Corp. 2.06% 550,811 $3.3M Add +30.9%
AEM Agnico Eagle Mines Ltd. 2.06% 55,500 $3.3M No change
VRNA Verona Pharma Ltd. 2.00% 200,000 $3.2M No change
SILV Silvercrest Metals Inc. 1.95% 470,000 $3.1M No change
FNV Franco-Nevada Corp. 1.85% 25,000 $3.0M New
MAG Mag Silver Corp. 1.81% 275,000 $2.9M Add +161.9%
WPM Wheaton Precious Metals Corp. 1.76% 60,000 $2.8M No change
KGC Kinross Gold Corp. 1.68% 440,000 $2.7M No change
BAH Booz Allen Hamilton Holdings 1.20% 13,000 $1.9M No change
OCUL Ocular Therapeutix Inc. 1.13% 200,400 $1.8M No change
V Visa Inc. Class A 0.84% 4,850 $1.4M No change
SIL Global X Silver Miners ETF 0.77% 45,175 $1.2M Reduce -74.3%
AGI Alamos Gold Inc. Class A 0.73% 80,000 $1.2M No change
CVS CVS Health Corp. 0.72% 14,500 $1.2M No change
SLV iShares Silver Trust 0.69% 48,500 $1.1M New
NOC Northrop Grumman Corp. 0.64% 2,165 $1.0M No change
ITA iShares U.S. Aerospace & Def 0.63% 7,650 $1.0M No change
DEO Diageo PLC-Sponsored ADR 0.62% 6,750 $1.0M New
RGLD Royal Gold Inc. 0.57% 7,550 $920K No change
PM Philip Morris International 0.57% 10,000 $916K No change
MREO Mereo Biopharma Group PL-ADR 0.53% 260,470 $860K Add +62.3%
NEWP New Pacific Metals Corp. 0.40% 485,000 $650K No change
Orgenesis, Inc. 0.32% 634,738 $522K No change
IRD Opus Genetics Inc. filed as OCUPHIRE PHARMA INC 0.13% 100,000 $201K No change
SKE Skeena Resources Ltd. 0.11% 38,786 $179K New

Portfolio Sells Q4 2023 → Q1 2024
SIL Global X Silver Miners ETF Reduce -74.3% 0.77% −3.36
GDX Vaneck Gold Miners ETF Sold out 0.00% −2.36
GDXJ Vaneck Junior Gold Miners Sold out 0.00% −1.67
TMO Thermo Fisher Scientific Inc. Sold out 0.00% −0.92

Portfolio Buys Q4 2023 → Q1 2024
APLT Applied Therapeutics Inc. Add +1.8% 23.58% +8.40
GLD SPDR Gold Shares New 4.10% +4.10
FNV Franco-Nevada Corp. New 1.85% +1.85
ALT Altimmune Inc. Add +183.6% 3.59% +1.73
MAG Mag Silver Corp. Add +161.9% 1.81% +0.91
SLV iShares Silver Trust New 0.69% +0.69
DEO Diageo PLC-Sponsored ADR New 0.62% +0.62
EQX Equinox Gold Corp. Add +30.9% 2.06% +0.36
MREO Mereo Biopharma Group PL-ADR Add +62.3% 0.53% +0.23
SKE Skeena Resources Ltd. New 0.11% +0.11

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026Amended 37$214.3MBIOHAVEN PHARMACEUTICAL HOLD, MGTX, PHYS, ALDX, OCUL
Q1 2026 37$188.7MBIOHAVEN PHARMACEUTICAL HOLD, PHYS, RGLD, MGTX, AEM
Q4 2025 33$218.0MALDX, BIOHAVEN PHARMACEUTICAL HOLD, NUVB, AVDL, GLD
Q3 2025 38$186.6MALDX, BIOHAVEN PHARMACEUTICAL HOLD, GLD, ENTX, MGTX
Q2 2025 38$140.7MALDX, BIOHAVEN PHARMACEUTICAL HOLD, ENTX, GLD, MGTX
Q1 2025 36$153.7MALDX, BIOHAVEN PHARMACEUTICAL HOLD, ENTX, GLD, MGTX
Q4 2024 35$155.3MBIOHAVEN PHARMACEUTICAL HOLD, ALDX, ENTX, VRNA, ALT
Q3 2024 36$215.8MAPLT, BIOHAVEN PHARMACEUTICAL HOLD, ALDX, AGI, AVDL
Q2 2024 35$148.4MAPLT, BIOHAVEN PHARMACEUTICAL HOLD, ALDX, AVDL, ALT
Q1 2024 34$160.7MAPLT, BIOHAVEN PHARMACEUTICAL HOLD, ALDX, AVDL, GLD