Knoll Capital Management, LLC

In its 13F for Q3 2024 (holdings as of September 30, 2024, filed November 14, 2024), Knoll Capital Management, LLC reported 36 stock positions worth $215.8 million. Its top holding was Applied Therapeutics (APLT) at 22.0% of the portfolio, followed by Biohaven Pharmaceutical Hold (16.5%) and Aldeyra Therapeutics (ALDX, 13.7%). Compared with Q2 2024, it opened 2 new positions, sold out of 1, added to 4 and reduced 6. The biggest buy was a new position in Meiragtx (MGTX) and the biggest sale Silvercrest Metals (SILV, shares −87%).

Most Recent 13F
Q2 2026
Location
MIAMI, FL
CIK
0001325083
Portfolio Value
$215.8M (Q3 2024)
SEC Filing
0001104659-24-118986 ↗ filed Nov 14, 2024

Holdings Value

0$50.0M$100.0M$150.0M$200.0M$250.0M Q1 2024: $160.7M Q1 2024 Q2 2024: $148.4M Q2 2024 Q3 2024: $215.8M $215.8M Q3 2024 Q4 2024: $155.3M Q4 2024 Q1 2025: $153.7M Q1 2025 Q2 2025: $140.7M Q2 2025 Q3 2025: $186.6M Q3 2025 Q4 2025: $218.0M Q4 2025 Q1 2026: $188.7M Q1 2026 Q2 2026: $214.3M Q2 2026

Holdings 36 stocks · $215.8M
APLT Applied Therapeutics Inc. 21.96% 5,574,687 $47.4M No change
BIOHAVEN PHARMACEUTICAL HOLD 16.45% 710,422 $35.5M No change
ALDX Aldeyra Therapeutics Inc. 13.68% 5,475,516 $29.5M No change
AGI Alamos Gold Inc. Class A 4.09% 41,000 $8.8M Reduce -48.8%
AVDL Avadel Pharmaceuticals plc 3.65% 600,000 $7.9M No change
GLD SPDR Gold Shares 3.60% 32,000 $7.8M No change
ENTX Entera Bio Ltd. 3.42% 3,881,879 $7.4M No change
HOOKIPA PHARMA INC 3.33% 551,738 $7.2M Reduce -90.0%
ALT Altimmune Inc. 3.19% 1,121,524 $6.9M No change
VRNA Verona Pharma Ltd. 2.67% 200,000 $5.8M No change
SA Seabridge Gold Inc. 2.47% 317,003 $5.3M Add +28.6%
OCUL Ocular Therapeutix Inc. 2.42% 600,400 $5.2M Add +199.6%
MGTX Meiragtx Holdings PLC 2.42% 1,250,000 $5.2M New
AEM Agnico Eagle Mines Ltd. 2.07% 55,500 $4.5M No change
KGC Kinross Gold Corp. 1.91% 440,000 $4.1M No change
EQX Equinox Gold Corp. 1.55% 550,811 $3.4M No change
FNV Franco-Nevada Corp. 1.44% 25,000 $3.1M No change
SKE Skeena Resources Ltd. 1.24% 315,400 $2.7M Add +713.2%
MAG Mag Silver Corp. 1.11% 170,000 $2.4M Reduce -38.2%
SLV iShares Silver Trust 1.05% 80,000 $2.3M Add +65.0%
BAH Booz Allen Hamilton Holdings 0.98% 13,000 $2.1M No change
V Visa Inc. Class A 0.62% 4,850 $1.3M No change
PM Philip Morris International 0.56% 10,000 $1.2M No change
ITA iShares U.S. Aerospace & Def 0.53% 7,650 $1.1M No change
NOC Northrop Grumman Corp. 0.53% 2,165 $1.1M No change
MREO Mereo Biopharma Group PL-ADR 0.50% 260,470 $1.1M No change
RGLD Royal Gold Inc. 0.49% 7,550 $1.1M No change
DEO Diageo PLC-Sponsored ADR 0.44% 6,750 $947K No change
CVS CVS Health Corp. 0.42% 14,500 $912K No change
WPM Wheaton Precious Metals Corp. 0.35% 12,500 $764K Reduce -79.2%
NEWP New Pacific Metals Corp. 0.33% 485,000 $723K No change
SILV Silvercrest Metals Inc. 0.26% 60,000 $555K Reduce -87.2%
Orgenesis, Inc. 0.13% 63,473 $283K Reduce -90.0%
CRDL Cardiol Therapeutics Inc. Class A 0.09% 100,000 $198K No change
IRD Opus Genetics Inc. filed as OCUPHIRE PHARMA INC 0.06% 100,000 $131K No change
GRAL Grail Inc. 0.00% 100 $1K New

Portfolio Sells Q2 2024 → Q3 2024
SILV Silvercrest Metals Inc. Reduce -87.2% 0.26% −2.32
WPM Wheaton Precious Metals Corp. Reduce -79.2% 0.35% −1.77
MAG Mag Silver Corp. Reduce -38.2% 1.11% −1.06
SIL Global X Silver Miners ETF Sold out 0.00% −0.95
Orgenesis, Inc. Reduce -90.0% 0.13% −0.13
HOOKIPA PHARMA INC Reduce -90.0% 3.33% +1.13
AGI Alamos Gold Inc. Class A Reduce -48.8% 4.09% +3.24

Portfolio Buys Q2 2024 → Q3 2024
MGTX Meiragtx Holdings PLC New 2.42% +2.42
OCUL Ocular Therapeutix Inc. Add +199.6% 2.42% +1.50
SKE Skeena Resources Ltd. Add +713.2% 1.24% +1.10
SA Seabridge Gold Inc. Add +28.6% 2.47% +0.19
SLV iShares Silver Trust Add +65.0% 1.05% +0.18
GRAL Grail Inc. New 0.00% +0.00

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026Amended 37$214.3MBIOHAVEN PHARMACEUTICAL HOLD, MGTX, PHYS, ALDX, OCUL
Q1 2026 37$188.7MBIOHAVEN PHARMACEUTICAL HOLD, PHYS, RGLD, MGTX, AEM
Q4 2025 33$218.0MALDX, BIOHAVEN PHARMACEUTICAL HOLD, NUVB, AVDL, GLD
Q3 2025 38$186.6MALDX, BIOHAVEN PHARMACEUTICAL HOLD, GLD, ENTX, MGTX
Q2 2025 38$140.7MALDX, BIOHAVEN PHARMACEUTICAL HOLD, ENTX, GLD, MGTX
Q1 2025 36$153.7MALDX, BIOHAVEN PHARMACEUTICAL HOLD, ENTX, GLD, MGTX
Q4 2024 35$155.3MBIOHAVEN PHARMACEUTICAL HOLD, ALDX, ENTX, VRNA, ALT
Q3 2024 36$215.8MAPLT, BIOHAVEN PHARMACEUTICAL HOLD, ALDX, AGI, AVDL
Q2 2024 35$148.4MAPLT, BIOHAVEN PHARMACEUTICAL HOLD, ALDX, AVDL, ALT
Q1 2024 34$160.7MAPLT, BIOHAVEN PHARMACEUTICAL HOLD, ALDX, AVDL, GLD