Knoll Capital Management, LLC

In its 13F for Q2 2025 (holdings as of June 30, 2025, filed August 14, 2025), Knoll Capital Management, LLC reported 38 stock positions worth $140.7 million. Its top holding was Aldeyra Therapeutics (ALDX) at 14.9% of the portfolio, followed by Biohaven Pharmaceutical Hold (9.0%) and Entera Bio (ENTX, 7.9%). Compared with Q1 2025, it opened 3 new positions, sold out of 1, added to 3 and reduced 1. The biggest buy was Royal Gold (RGLD, shares +19%) and the biggest sale an exit from Equinox Gold (EQX).

Most Recent 13F
Q2 2026
Location
MIAMI, FL
CIK
0001325083
Portfolio Value
$140.7M (Q2 2025)
SEC Filing
0001104659-25-078541 ↗ filed Aug 14, 2025

Holdings Value

0$50.0M$100.0M$150.0M$200.0M$250.0M Q1 2024: $160.7M Q1 2024 Q2 2024: $148.4M Q2 2024 Q3 2024: $215.8M Q3 2024 Q4 2024: $155.3M Q4 2024 Q1 2025: $153.7M Q1 2025 Q2 2025: $140.7M $140.7M Q2 2025 Q3 2025: $186.6M Q3 2025 Q4 2025: $218.0M Q4 2025 Q1 2026: $188.7M Q1 2026 Q2 2026: $214.3M Q2 2026

Holdings 38 stocks · $140.7M
ALDX Aldeyra Therapeutics Inc. 14.91% 5,475,516 $21.0M No change
BIOHAVEN PHARMACEUTICAL HOLD 8.98% 895,269 $12.6M Add +7.8%
ENTX Entera Bio Ltd. 7.95% 5,881,879 $11.2M No change
GLD SPDR Gold Shares 6.94% 32,000 $9.8M No change
MGTX Meiragtx Holdings PLC 5.79% 1,250,000 $8.2M No change
KGC Kinross Gold Corp. 4.89% 440,000 $6.9M No change
AEM Agnico Eagle Mines Ltd. 4.69% 55,500 $6.6M No change
SAND Sandstorm Gold Ltd. 4.68% 700,000 $6.6M No change
AVDL Avadel Pharmaceuticals plc 3.78% 600,000 $5.3M No change
ELTX Elicio Therapeutics Inc. 3.46% 630,915 $4.9M No change
SKE Skeena Resources Ltd. 3.34% 295,400 $4.7M Reduce -6.3%
SA Seabridge Gold Inc. 3.27% 317,003 $4.6M No change
ALT Altimmune Inc. 3.09% 1,121,524 $4.3M No change
FNV Franco-Nevada Corp. 2.91% 25,000 $4.1M No change
MAG Mag Silver Corp. 2.55% 170,000 $3.6M No change
NUVB Nuvation Bio Inc. 2.08% 1,025,000 $2.9M No change
SLV iShares Silver Trust 1.87% 80,000 $2.6M No change
APLT Applied Therapeutics Inc. 1.72% 7,799,687 $2.4M No change
OCUL Ocular Therapeutix Inc. 1.32% 600,400 $1.9M No change
PM Philip Morris International 1.29% 10,000 $1.8M No change
V Visa Inc. Class A 1.22% 4,850 $1.7M No change
RGLD Royal Gold Inc. 1.14% 9,000 $1.6M Add +19.2%
ITA iShares U.S. Aerospace & Def 1.03% 7,650 $1.4M No change
BAH Booz Allen Hamilton Holdings 0.96% 13,000 $1.4M No change
AGI Alamos Gold Inc. Class A 0.94% 50,000 $1.3M Add +21.9%
WPM Wheaton Precious Metals Corp. 0.80% 12,500 $1.1M No change
NOC Northrop Grumman Corp. 0.77% 2,165 $1.1M No change
CDE Coeur Mining Inc. 0.61% 96,132 $852K No change
MREO Mereo Biopharma Group PL-ADR 0.50% 260,470 $706K No change
DEO Diageo PLC-Sponsored ADR 0.48% 6,750 $681K No change
VRNA Verona Pharma Ltd. 0.47% 7,049 $667K No change
NEWP New Pacific Metals Corp. 0.46% 485,000 $650K No change
HOOKIPA PHARMA INC 0.44% 498,625 $626K No change
ABEO Abeona Therapeutics Inc. 0.25% 62,689 $356K New
CGAU Centerra Gold Inc. 0.12% 1,227,863 $170K New
OBIO Orchestra Biomed Holdings Inc. 0.12% 455,128 $170K New
CRDL Cardiol Therapeutics Inc. Class A 0.10% 100,000 $136K No change
Orgenesis, Inc. 0.05% 50,623 $75K No change

Portfolio Sells Q1 2025 → Q2 2025
EQX Equinox Gold Corp. Sold out 0.00% −2.47
SKE Skeena Resources Ltd. Reduce -6.3% 3.34% +1.27

Portfolio Buys Q1 2025 → Q2 2025
RGLD Royal Gold Inc. Add +19.2% 1.14% +0.33
ABEO Abeona Therapeutics Inc. New 0.25% +0.25
AGI Alamos Gold Inc. Class A Add +21.9% 0.94% +0.23
CGAU Centerra Gold Inc. New 0.12% +0.12
OBIO Orchestra Biomed Holdings Inc. New 0.12% +0.12
BIOHAVEN PHARMACEUTICAL HOLD Add +7.8% 8.98% −4.01

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026Amended 37$214.3MBIOHAVEN PHARMACEUTICAL HOLD, MGTX, PHYS, ALDX, OCUL
Q1 2026 37$188.7MBIOHAVEN PHARMACEUTICAL HOLD, PHYS, RGLD, MGTX, AEM
Q4 2025 33$218.0MALDX, BIOHAVEN PHARMACEUTICAL HOLD, NUVB, AVDL, GLD
Q3 2025 38$186.6MALDX, BIOHAVEN PHARMACEUTICAL HOLD, GLD, ENTX, MGTX
Q2 2025 38$140.7MALDX, BIOHAVEN PHARMACEUTICAL HOLD, ENTX, GLD, MGTX
Q1 2025 36$153.7MALDX, BIOHAVEN PHARMACEUTICAL HOLD, ENTX, GLD, MGTX
Q4 2024 35$155.3MBIOHAVEN PHARMACEUTICAL HOLD, ALDX, ENTX, VRNA, ALT
Q3 2024 36$215.8MAPLT, BIOHAVEN PHARMACEUTICAL HOLD, ALDX, AGI, AVDL
Q2 2024 35$148.4MAPLT, BIOHAVEN PHARMACEUTICAL HOLD, ALDX, AVDL, ALT
Q1 2024 34$160.7MAPLT, BIOHAVEN PHARMACEUTICAL HOLD, ALDX, AVDL, GLD