Knoll Capital Management, LLC

In its 13F for Q1 2025 (holdings as of March 31, 2025, filed May 15, 2025), Knoll Capital Management, LLC reported 36 stock positions worth $153.7 million. Its top holding was Aldeyra Therapeutics (ALDX) at 20.5% of the portfolio, followed by Biohaven Pharmaceutical Hold (13.0%) and Entera Bio (ENTX, 6.5%). Compared with Q4 2024, it opened 4 new positions, sold out of 3, added to 2 and reduced 1. The biggest buy was a new position in Sandstorm Gold (SAND) and the biggest sale Verona Pharma (VRNA, shares −96%).

Most Recent 13F
Q2 2026
Location
MIAMI, FL
CIK
0001325083
Portfolio Value
$153.7M (Q1 2025)
SEC Filing
0001104659-25-049384 ↗ filed May 15, 2025

Holdings Value

0$50.0M$100.0M$150.0M$200.0M$250.0M Q1 2024: $160.7M Q1 2024 Q2 2024: $148.4M Q2 2024 Q3 2024: $215.8M Q3 2024 Q4 2024: $155.3M Q4 2024 Q1 2025: $153.7M $153.7M Q1 2025 Q2 2025: $140.7M Q2 2025 Q3 2025: $186.6M Q3 2025 Q4 2025: $218.0M Q4 2025 Q1 2026: $188.7M Q1 2026 Q2 2026: $214.3M Q2 2026

Holdings 36 stocks · $153.7M
ALDX Aldeyra Therapeutics Inc. 20.48% 5,475,516 $31.5M No change
BIOHAVEN PHARMACEUTICAL HOLD 12.99% 830,879 $20.0M Add +9.3%
ENTX Entera Bio Ltd. 6.50% 5,881,879 $10.0M No change
GLD SPDR Gold Shares 6.00% 32,000 $9.2M No change
MGTX Meiragtx Holdings PLC 5.51% 1,250,000 $8.5M No change
AEM Agnico Eagle Mines Ltd. 3.91% 55,500 $6.0M No change
ALT Altimmune Inc. 3.65% 1,121,524 $5.6M No change
KGC Kinross Gold Corp. 3.61% 440,000 $5.5M No change
SAND Sandstorm Gold Ltd. 3.44% 700,000 $5.3M New
AVDL Avadel Pharmaceuticals plc 3.06% 600,000 $4.7M No change
OCUL Ocular Therapeutix Inc. 2.86% 600,400 $4.4M No change
FNV Franco-Nevada Corp. 2.56% 25,000 $3.9M No change
ELTX Elicio Therapeutics Inc. 2.53% 630,915 $3.9M New
APLT Applied Therapeutics Inc. 2.48% 7,799,687 $3.8M Add +34.5%
EQX Equinox Gold Corp. 2.47% 550,811 $3.8M No change
SA Seabridge Gold Inc. 2.41% 317,003 $3.7M No change
SKE Skeena Resources Ltd. 2.07% 315,400 $3.2M No change
MAG Mag Silver Corp. 1.69% 170,000 $2.6M No change
SLV iShares Silver Trust 1.61% 80,000 $2.5M No change
NUVB Nuvation Bio Inc. 1.17% 1,025,000 $1.8M New
V Visa Inc. Class A 1.11% 4,850 $1.7M No change
PM Philip Morris International 1.03% 10,000 $1.6M No change
BAH Booz Allen Hamilton Holdings 0.88% 13,000 $1.4M No change
RGLD Royal Gold Inc. 0.80% 7,550 $1.2M No change
ITA iShares U.S. Aerospace & Def 0.76% 7,650 $1.2M No change
NOC Northrop Grumman Corp. 0.72% 2,165 $1.1M No change
AGI Alamos Gold Inc. Class A 0.71% 41,000 $1.1M No change
WPM Wheaton Precious Metals Corp. 0.63% 12,500 $970K No change
DEO Diageo PLC-Sponsored ADR 0.46% 6,750 $707K No change
MREO Mereo Biopharma Group PL-ADR 0.38% 260,470 $586K No change
CDE Coeur Mining Inc. 0.37% 96,132 $569K New
HOOKIPA PHARMA INC 0.35% 498,625 $539K No change
NEWP New Pacific Metals Corp. 0.35% 485,000 $536K No change
VRNA Verona Pharma Ltd. 0.29% 7,049 $448K Reduce -96.5%
Orgenesis, Inc. 0.08% 50,623 $124K No change
CRDL Cardiol Therapeutics Inc. Class A 0.06% 100,000 $97K No change

Portfolio Sells Q4 2024 → Q1 2025
VRNA Verona Pharma Ltd. Reduce -96.5% 0.29% −5.69
SILV Silvercrest Metals Inc. Sold out 0.00% −0.35
GRAL Grail Inc. Sold out 0.00% −0.00
IRD Opus Genetics Inc. Sold out 0.00% 0.00

Portfolio Buys Q4 2024 → Q1 2025
SAND Sandstorm Gold Ltd. New 3.44% +3.44
ELTX Elicio Therapeutics Inc. New 2.53% +2.53
NUVB Nuvation Bio Inc. New 1.17% +1.17
CDE Coeur Mining Inc. New 0.37% +0.37
APLT Applied Therapeutics Inc. Add +34.5% 2.48% −0.72
BIOHAVEN PHARMACEUTICAL HOLD Add +9.3% 12.99% −5.29

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026Amended 37$214.3MBIOHAVEN PHARMACEUTICAL HOLD, MGTX, PHYS, ALDX, OCUL
Q1 2026 37$188.7MBIOHAVEN PHARMACEUTICAL HOLD, PHYS, RGLD, MGTX, AEM
Q4 2025 33$218.0MALDX, BIOHAVEN PHARMACEUTICAL HOLD, NUVB, AVDL, GLD
Q3 2025 38$186.6MALDX, BIOHAVEN PHARMACEUTICAL HOLD, GLD, ENTX, MGTX
Q2 2025 38$140.7MALDX, BIOHAVEN PHARMACEUTICAL HOLD, ENTX, GLD, MGTX
Q1 2025 36$153.7MALDX, BIOHAVEN PHARMACEUTICAL HOLD, ENTX, GLD, MGTX
Q4 2024 35$155.3MBIOHAVEN PHARMACEUTICAL HOLD, ALDX, ENTX, VRNA, ALT
Q3 2024 36$215.8MAPLT, BIOHAVEN PHARMACEUTICAL HOLD, ALDX, AGI, AVDL
Q2 2024 35$148.4MAPLT, BIOHAVEN PHARMACEUTICAL HOLD, ALDX, AVDL, ALT
Q1 2024 34$160.7MAPLT, BIOHAVEN PHARMACEUTICAL HOLD, ALDX, AVDL, GLD