MPM Asset Management LLC
In its 13F for Q4 2024 (holdings as of December 31, 2024, filed February 14, 2025), MPM Asset Management LLC reported 6 stock positions worth $124.4 million. Its top holding was Entrada Therapeutics (TRDA) at 60.9% of the portfolio, followed by Iteos Therapeutics (ITOS, 16.9%) and Dyne Therapeutics (DYN, 12.9%). Compared with Q3 2024, it reduced 2. The biggest sale was Repare Therapeutics (RPTX, shares −25%).
- Most Recent 13F
- Q3 2025
- Location
- BOSTON, MA
- CIK
- 0001263048
- Portfolio Value
- $124.4M (Q4 2024)
- SEC Filing
- 0000950123-25-002793 ↗ filed Feb 14, 2025
Holdings Value
Holdings 6 stocks · $124.4M
| TRDA Entrada Therapeutics Inc. | 60.89% | 4,381,062 | $75.7M | Reduce -1.0% |
| ITOS Iteos Therapeutics Inc. | 16.91% | 2,738,785 | $21.0M | No change |
| DYN Dyne Therapeutics Inc. | 12.92% | 682,376 | $16.1M | No change |
| HOWL Werewolf Therapeutics Inc. | 5.10% | 4,284,172 | $6.3M | No change |
| ADAPY Adaptimmune Therapeutics-ADR | 2.41% | 5,555,461 | $3.0M | No change |
| RPTX Repare Therapeutics Inc. | 1.77% | 1,683,707 | $2.2M | Reduce -24.9% |
Portfolio Sells Q3 2024 → Q4 2024
Portfolio Buys Q3 2024 → Q4 2024
| None this quarter. | |||
All Filings
| Quarter | Positions | 13F Reported Value | Top Holdings |
|---|---|---|---|
| Q3 2025 | 4 | $44.5M | TRDA, DYN, HOWL, RPTX |
| Q2 2025 | 5 | $43.3M | TRDA, DYN, HOWL, RPTX, ADAPY |
| Q1 2025 | 6 | $69.4M | TRDA, ITOS, DYN, HOWL, RPTX |
| Q4 2024 | 6 | $124.4M | TRDA, ITOS, DYN, HOWL, ADAPY |
| Q3 2024 | 6 | $145.3M | TRDA, ITOS, DYN, HOWL, RPTX |
| Q2 2024 | 6 | $182.1M | TRDA, DYN, ITOS, HOWL, RPTX |
| Q1 2024 | 6 | $245.2M | DYN, TRDA, ITOS, HOWL, RPTX |