MPM Asset Management LLC
In its 13F for Q1 2025 (holdings as of March 31, 2025, filed May 15, 2025), MPM Asset Management LLC reported 6 stock positions worth $69.4 million. Its top holding was Entrada Therapeutics (TRDA) at 57.0% of the portfolio, followed by Iteos Therapeutics (ITOS, 23.5%) and Dyne Therapeutics (DYN, 10.3%). Compared with Q4 2024, it added to 1 and reduced 2. The biggest buy was Werewolf Therapeutics (HOWL, shares +1%) and the biggest sale Adaptimmune Therapeutics-ADR (ADAPY, shares −4%).
- Most Recent 13F
- Q3 2025
- Location
- BOSTON, MA
- CIK
- 0001263048
- Portfolio Value
- $69.4M (Q1 2025)
- SEC Filing
- 0000950123-25-005757 ↗ filed May 15, 2025
Holdings Value
Holdings 6 stocks · $69.4M
| TRDA Entrada Therapeutics Inc. | 57.04% | 4,381,062 | $39.6M | No change |
| ITOS Iteos Therapeutics Inc. | 23.55% | 2,738,785 | $16.4M | No change |
| DYN Dyne Therapeutics Inc. | 10.28% | 682,376 | $7.1M | No change |
| HOWL Werewolf Therapeutics Inc. | 6.03% | 4,309,860 | $4.2M | Add +0.6% |
| RPTX Repare Therapeutics Inc. | 1.59% | 1,121,318 | $1.1M | Reduce -33.4% |
| ADAPY Adaptimmune Therapeutics-ADR | 1.51% | 5,335,715 | $1.1M | Reduce -4.0% |
Portfolio Sells Q4 2024 → Q1 2025
Portfolio Buys Q4 2024 → Q1 2025
| HOWL Werewolf Therapeutics Inc. | Add +0.6% | 6.03% | +0.94 |
All Filings
| Quarter | Positions | 13F Reported Value | Top Holdings |
|---|---|---|---|
| Q3 2025 | 4 | $44.5M | TRDA, DYN, HOWL, RPTX |
| Q2 2025 | 5 | $43.3M | TRDA, DYN, HOWL, RPTX, ADAPY |
| Q1 2025 | 6 | $69.4M | TRDA, ITOS, DYN, HOWL, RPTX |
| Q4 2024 | 6 | $124.4M | TRDA, ITOS, DYN, HOWL, ADAPY |
| Q3 2024 | 6 | $145.3M | TRDA, ITOS, DYN, HOWL, RPTX |
| Q2 2024 | 6 | $182.1M | TRDA, DYN, ITOS, HOWL, RPTX |
| Q1 2024 | 6 | $245.2M | DYN, TRDA, ITOS, HOWL, RPTX |