MPM Asset Management LLC
In its 13F for Q2 2025 (holdings as of June 30, 2025, filed August 14, 2025), MPM Asset Management LLC reported 5 stock positions worth $43.3 million. Its top holding was Entrada Therapeutics (TRDA) at 67.9% of the portfolio, followed by Dyne Therapeutics (DYN, 15.0%) and Werewolf Therapeutics (HOWL, 10.8%). Compared with Q1 2025, it sold out of 1 and reduced 1. The biggest sale was an exit from Iteos Therapeutics (ITOS).
- Most Recent 13F
- Q3 2025
- Location
- BOSTON, MA
- CIK
- 0001263048
- Portfolio Value
- $43.3M (Q2 2025)
- SEC Filing
- 0000950123-25-008430 ↗ filed Aug 14, 2025
Holdings Value
Holdings 5 stocks · $43.3M
| TRDA Entrada Therapeutics Inc. | 67.92% | 4,381,062 | $29.4M | No change |
| DYN Dyne Therapeutics Inc. | 14.99% | 682,376 | $6.5M | No change |
| HOWL Werewolf Therapeutics Inc. | 10.84% | 4,309,860 | $4.7M | No change |
| RPTX Repare Therapeutics Inc. | 3.60% | 1,121,318 | $1.6M | No change |
| ADAPY Adaptimmune Therapeutics-ADR | 2.66% | 4,809,677 | $1.2M | Reduce -9.9% |
Portfolio Sells Q1 2025 → Q2 2025
Portfolio Buys Q1 2025 → Q2 2025
| None this quarter. | |||
All Filings
| Quarter | Positions | 13F Reported Value | Top Holdings |
|---|---|---|---|
| Q3 2025 | 4 | $44.5M | TRDA, DYN, HOWL, RPTX |
| Q2 2025 | 5 | $43.3M | TRDA, DYN, HOWL, RPTX, ADAPY |
| Q1 2025 | 6 | $69.4M | TRDA, ITOS, DYN, HOWL, RPTX |
| Q4 2024 | 6 | $124.4M | TRDA, ITOS, DYN, HOWL, ADAPY |
| Q3 2024 | 6 | $145.3M | TRDA, ITOS, DYN, HOWL, RPTX |
| Q2 2024 | 6 | $182.1M | TRDA, DYN, ITOS, HOWL, RPTX |
| Q1 2024 | 6 | $245.2M | DYN, TRDA, ITOS, HOWL, RPTX |