MPM Asset Management LLC

In its 13F for Q3 2025 (holdings as of September 30, 2025, filed November 14, 2025), MPM Asset Management LLC reported 4 stock positions worth $44.5 million. Its top holding was Entrada Therapeutics (TRDA) at 57.1% of the portfolio, followed by Dyne Therapeutics (DYN, 19.4%) and Werewolf Therapeutics (HOWL, 19.1%). Compared with Q2 2025, it sold out of 1. The biggest sale was an exit from Adaptimmune Therapeutics-ADR (ADAPY).

Most Recent 13F
Q3 2025
Location
BOSTON, MA
CIK
0001263048
Portfolio Value
$44.5M (Q3 2025)
SEC Filing
0001193125-25-283116 ↗ filed Nov 14, 2025

Holdings Value

0$50.0M$100.0M$150.0M$200.0M$250.0M Q1 2024: $245.2M Q1 2024 Q2 2024: $182.1M Q2 2024 Q3 2024: $145.3M Q3 2024 Q4 2024: $124.4M Q4 2024 Q1 2025: $69.4M Q1 2025 Q2 2025: $43.3M Q2 2025 Q3 2025: $44.5M $44.5M Q3 2025

Holdings 4 stocks · $44.5M
TRDA Entrada Therapeutics Inc. 57.09% 4,381,062 $25.4M No change
DYN Dyne Therapeutics Inc. 19.40% 682,376 $8.6M No change
HOWL Werewolf Therapeutics Inc. 19.08% 4,309,860 $8.5M No change
RPTX Repare Therapeutics Inc. 4.43% 1,121,318 $2.0M No change

Portfolio Sells Q2 2025 → Q3 2025
ADAPY Adaptimmune Therapeutics-ADR Sold out 0.00% −2.66

Portfolio Buys Q2 2025 → Q3 2025
None this quarter.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q3 2025 4$44.5MTRDA, DYN, HOWL, RPTX
Q2 2025 5$43.3MTRDA, DYN, HOWL, RPTX, ADAPY
Q1 2025 6$69.4MTRDA, ITOS, DYN, HOWL, RPTX
Q4 2024 6$124.4MTRDA, ITOS, DYN, HOWL, ADAPY
Q3 2024 6$145.3MTRDA, ITOS, DYN, HOWL, RPTX
Q2 2024 6$182.1MTRDA, DYN, ITOS, HOWL, RPTX
Q1 2024 6$245.2MDYN, TRDA, ITOS, HOWL, RPTX