Rhenman & Partners Asset Management AB

In its 13F for Q4 2025 (holdings as of December 31, 2025, filed February 13, 2026), Rhenman & Partners Asset Management AB reported 94 stock positions worth $1.1 billion. Its top holding was Regeneron Pharmaceuticals (REGN) at 4.4% of the portfolio, followed by Eli Lilly (LLY, 4.2%) and Boston Scientific (BSX, 3.8%). Compared with Q3 2025, it opened 13 new positions, sold out of 11, added to 43 and reduced 32. The biggest buy was Regeneron Pharmaceuticals (REGN, shares +70%) and the biggest sale an exit from Exact Sciences (EXAS).

Most Recent 13F
Q2 2026
Location
Stockholm, V7
CIK
0001599882
Portfolio Value
$1.1B (Q4 2025)
SEC Filing
0001213900-26-015821 ↗ filed Feb 13, 2026

Holdings Value

0$500.0M$1.0B$1.5B Q1 2024: $1.1B Q1 2024 Q2 2024: $1.0B Q2 2024 Q3 2024: $1.2B Q3 2024 Q4 2024: $972.9M Q4 2024 Q1 2025: $870.0M Q1 2025 Q2 2025: $791.0M Q2 2025 Q3 2025: $903.7M Q3 2025 Q4 2025: $1.1B $1.1B Q4 2025 Q1 2026: $810.5M Q1 2026 Q2 2026: $1.1B Q2 2026

Holdings 94 stocks · $1.1B

REGN Regeneron Pharmaceuticals 4.43% 61,400 $47.4M Add +70.1%
LLY Eli Lilly & Co. 4.24% 42,220 $45.4M Reduce -21.0%
BSX Boston Scientific Corp. 3.84% 431,207 $41.1M Reduce -1.6%
MDT Medtronic PLC 2.66% 296,000 $28.4M Add +44.4%
ISRG Intuitive Surgical Inc. 2.54% 48,000 $27.2M Reduce -1.0%
COO The Cooper Cos Inc. 2.51% 327,500 $26.8M Add +38.2%
CVS CVS Health Corp. 2.49% 335,500 $26.6M Add +21.0%
ABBV Abbvie Inc. 2.36% 110,575 $25.3M Reduce -15.2%
GKOS Glaukos Corp. 2.22% 210,000 $23.7M Reduce -8.7%
DHR Danaher Corp. 2.12% 99,052 $22.7M Reduce -26.3%
COR Cencora Inc. 2.00% 63,375 $21.4M Add +1.6%
VERA Vera Therapeutics Inc. 1.99% 420,000 $21.3M Add +223.1%
MCK McKesson Corp. 1.96% 25,600 $21.0M Reduce -3.8%
AXSM Axsome Therapeutics Inc. 1.96% 114,800 $21.0M Reduce -33.6%
ALHC Alignment Healthcare Inc. 1.86% 1,009,450 $19.9M Reduce -31.8%
INSM Insmed Inc. 1.85% 113,585 $19.8M Reduce -13.9%
TMO Thermo Fisher Scientific Inc. 1.82% 33,640 $19.5M Add +12.0%
PRCT Procept Biorobotics Corp. 1.80% 611,000 $19.2M Add +56.7%
ALNY Alnylam Pharmaceuticals Inc. 1.70% 45,675 $18.2M Add +43.3%
UNH Unitedhealth Group Inc. 1.69% 54,900 $18.1M Reduce -12.2%
NBIX Neurocrine Biosciences Inc. 1.66% 125,491 $17.8M Add +9.4%
PODD Insulet Corp. 1.62% 61,000 $17.3M Add +5.2%
DOCS Doximity Inc. Class A 1.54% 372,750 $16.5M Add +174.1%
EW Edwards Lifesciences Corp. 1.54% 193,500 $16.5M Add +24.8%
NUVL Nuvalent Inc. Class A 1.54% 163,350 $16.4M Add +211.1%
BIIB Biogen Inc. 1.52% 92,350 $16.3M Add +67.9%
VRTX Vertex Pharmaceuticals Inc. 1.45% 34,255 $15.5M Reduce -27.1%
EHC Encompass Health Corp. 1.45% 146,263 $15.5M Add +22.5%
GILD Gilead Sciences Inc. 1.45% 126,150 $15.5M Add +57.4%
ALGN Align Technology Inc. 1.44% 99,000 $15.5M Add +19.3%
THC Tenet Healthcare Corp. 1.42% 76,504 $15.2M Add +30.9%
BMRN Biomarin Pharmaceutical Inc. 1.19% 215,000 $12.8M Add +15.2%
JAZZ Jazz Pharmaceuticals PLC 1.18% 74,030 $12.6M Reduce -22.1%
IONS Ionis Pharmaceuticals Inc. 1.17% 158,500 $12.5M Reduce -48.9%
AMGN Amgen Inc. 1.10% 36,000 $11.8M New
LIVN Livanova PLC 1.09% 190,000 $11.7M Add +258.5%
MDGL Madrigal Pharmaceuticals Inc. 1.06% 19,550 $11.4M Add +7.1%
CI The Cigna Group 0.99% 38,650 $10.6M Reduce -16.9%
GPCR Structure Therapeutics Inc. 0.96% 147,600 $10.3M Reduce -18.1%
SNDX Syndax Pharmaceuticals Inc. 0.96% 487,000 $10.2M Reduce -15.2%
NRIX Nurix Therapeutics Inc. 0.95% 537,500 $10.2M Add +54.7%
PNTG The Pennant Group Inc. 0.94% 357,346 $10.1M New
ADPT Adaptive Biotechnologies 0.92% 605,000 $9.8M Add +22.2%
PEN Penumbra Inc. 0.92% 31,500 $9.8M Add +53.7%
ARWR Arrowhead Pharmaceuticals Inc. 0.90% 144,500 $9.6M New
APLS Apellis Pharmaceuticals Inc. 0.88% 374,450 $9.4M Add +61.2%
NTRA Natera Inc. 0.87% 40,500 $9.3M Add +30.6%
KURA Kura Oncology Inc. 0.85% 872,000 $9.1M Add +78.0%
ACLX Arcellx Inc. 0.81% 133,500 $8.7M Add +104.6%
IDYA Ideaya Biosciences Inc. 0.81% 250,000 $8.6M New
MIRM Mirum Pharmaceuticals Inc. 0.78% 106,255 $8.4M Add +88.9%
GH Guardant Health Inc. 0.76% 80,000 $8.2M Add +60.0%
RPRX Royalty Pharma PLC Class A 0.75% 206,500 $8.0M Reduce -20.1%
BTSG Brightspring Health Services 0.69% 198,000 $7.4M Add +230.0%
BRKR Bruker Corp. 0.65% 147,315 $6.9M Reduce -4.5%
STOK Stoke Therapeutics Inc. 0.64% 216,000 $6.9M Reduce -13.6%
BBIO Bridgebio Pharma Inc. 0.58% 81,600 $6.2M New
XENE Xenon Pharmaceuticals Inc. 0.58% 139,000 $6.2M Add +71.6%
AVR Anteris Technologies Global 0.58% 1,238,625 $6.2M Reduce -1.0%
KRYS Krystal Biotech Inc. 0.58% 25,000 $6.2M Add +112.8%
IQV Iqvia Holdings Inc. 0.56% 26,500 $6.0M Add +35.9%
IMCR Immunocore Holdings PLC-ADR 0.50% 153,278 $5.3M Add +442.0%
ELV Elevance Health Inc. 0.49% 15,000 $5.3M Reduce -33.3%
MLYS Mineralys Therapeutics Inc. 0.48% 142,571 $5.2M Reduce -13.6%
MLTX Moonlake Immunotherapeutics 0.45% 364,000 $4.8M Add +75.8%
CRL Charles River Laboratories 0.41% 22,000 $4.4M New
IOVA Iovance Biotherapeutics Inc. 0.41% 1,595,327 $4.4M Add +45.3%
VCEL Vericel Corp. 0.39% 117,000 $4.2M No change
DNTH Dianthus Therapeutics Inc. 0.38% 98,627 $4.1M Reduce -43.2%
RLAY Relay Therapeutics Inc. 0.36% 460,000 $3.9M No change
RYTM Rhythm Pharmaceuticals Inc. 0.35% 35,000 $3.7M No change
OSCR Oscar Health Inc. Class A 0.35% 260,000 $3.7M New
ALKS Alkermes PLC 0.35% 133,250 $3.7M Add +41.8%
RDNT Radnet Inc. 0.31% 47,000 $3.4M Reduce -6.0%
INSP Inspire Medical Systems Inc. 0.31% 35,800 $3.3M Reduce -41.3%
OCUL Ocular Therapeutix Inc. 0.30% 265,000 $3.2M Add +31.2%
ASND Ascendis Pharma A/S 0.30% 15,000 $3.2M New
JANX Janux Therapeutics Inc. 0.29% 225,377 $3.1M Add +125.1%
PRVA Privia Health Group Inc. 0.28% 125,000 $3.0M Reduce -35.6%
STVN Stevanato Group SPA 0.28% 147,025 $3.0M Add +188.3%
VKTX Viking Therapeutics Inc. 0.27% 83,000 $2.9M Reduce -61.6%
CYTK Cytokinetics Inc. 0.26% 44,375 $2.8M Reduce -82.6%
A Agilent Technologies Inc. 0.25% 20,000 $2.7M New
XNCR Xencor Inc. 0.24% 165,750 $2.5M No change
CNTA Centessa Pharmaceuticals Ltd. 0.23% 100,000 $2.5M New
TGTX TG Therapeutics Inc. 0.20% 73,250 $2.2M Reduce -21.2%
BNTX Biontech SE-ADR 0.19% 20,870 $2.0M Reduce -41.8%
WST West Pharmaceutical Services 0.18% 7,000 $1.9M New
CNC Centene Corp. 0.18% 46,231 $1.9M Reduce -72.8%
QURE Uniqure NV 0.18% 79,375 $1.9M New
DNLI Denali Therapeutics Inc. 0.15% 100,000 $1.7M No change
STE Steris PLC 0.14% 6,000 $1.5M New
IRTC Irhythm Holdings Inc. 0.12% 7,000 $1.2M No change
ATEC Alphatec Holdings Inc. 0.04% 20,000 $421K Add +11.1%

Portfolio Sells Q3 2025 → Q4 2025

EXAS Exact Sciences Corp. Sold out 0.00% −2.11
CAH Cardinal Health Inc. Sold out 0.00% −1.63
ABT Abbott Laboratories Sold out 0.00% −1.46
CYTK Cytokinetics Inc. Reduce -82.6% 0.26% −1.29
AKRO Akero Therapeutics Inc. Sold out 0.00% −1.21
IONS Ionis Pharmaceuticals Inc. Reduce -48.9% 1.17% −1.07
ALHC Alignment Healthcare Inc. Reduce -31.8% 1.86% −0.99
ABBV Abbvie Inc. Reduce -15.2% 2.36% −0.98
BSX Boston Scientific Corp. Reduce -1.6% 3.84% −0.89
DVAX Dynavax Technologies Corp. Sold out 0.00% −0.85
DHR Danaher Corp. Reduce -26.3% 2.12% −0.83
UNH Unitedhealth Group Inc. Reduce -12.2% 1.69% −0.70
VRTX Vertex Pharmaceuticals Inc. Reduce -27.1% 1.45% −0.58
MRUS Merus NV Sold out 0.00% −0.56
CNC Centene Corp. Reduce -72.8% 0.18% −0.49
CI The Cigna Group Reduce -16.9% 0.99% −0.49
RARE Ultragenyx Pharmaceutical Inc. Sold out 0.00% −0.40
DNTH Dianthus Therapeutics Inc. Reduce -43.2% 0.38% −0.38
UTHR United Therapeutics Corp. Sold out 0.00% −0.37
AXSM Axsome Therapeutics Inc. Reduce -33.6% 1.96% −0.36
VKTX Viking Therapeutics Inc. Reduce -61.6% 0.27% −0.36
ELV Elevance Health Inc. Reduce -33.3% 0.49% −0.31
MCK McKesson Corp. Reduce -3.8% 1.96% −0.31
ANNX Annexon Inc. Sold out 0.00% −0.28
UHS Universal Health Services-B Sold out 0.00% −0.27
LLY Eli Lilly & Co. Reduce -21.0% 4.24% −0.27
RPRX Royalty Pharma PLC Class A Reduce -20.1% 0.75% −0.26
PRVA Privia Health Group Inc. Reduce -35.6% 0.28% −0.26
INSM Insmed Inc. Reduce -13.9% 1.85% −0.25
JAZZ Jazz Pharmaceuticals PLC Reduce -22.1% 1.18% −0.21
MLYS Mineralys Therapeutics Inc. Reduce -13.6% 0.48% −0.21
BNTX Biontech SE-ADR Reduce -41.8% 0.19% −0.21
INSP Inspire Medical Systems Inc. Reduce -41.3% 0.31% −0.19
TGTX TG Therapeutics Inc. Reduce -21.2% 0.20% −0.17
RDNT Radnet Inc. Reduce -6.0% 0.31% −0.11
TECH Bio-Techne Corp. Sold out 0.00% −0.09
AVR Anteris Technologies Global Reduce -1.0% 0.58% −0.05
SNDX Syndax Pharmaceuticals Inc. Reduce -15.2% 0.96% −0.02
STOK Stoke Therapeutics Inc. Reduce -13.6% 0.64% −0.01
BRKR Bruker Corp. Reduce -4.5% 0.65% +0.09
GKOS Glaukos Corp. Reduce -8.7% 2.22% +0.14
ISRG Intuitive Surgical Inc. Reduce -1.0% 2.54% +0.14
GPCR Structure Therapeutics Inc. Reduce -18.1% 0.96% +0.40

Portfolio Buys Q3 2025 → Q4 2025

REGN Regeneron Pharmaceuticals Add +70.1% 4.43% +2.18
VERA Vera Therapeutics Inc. Add +223.1% 1.99% +1.57
AMGN Amgen Inc. New 1.10% +1.10
NUVL Nuvalent Inc. Class A Add +211.1% 1.54% +1.03
PNTG The Pennant Group Inc. New 0.94% +0.94
ARWR Arrowhead Pharmaceuticals Inc. New 0.90% +0.90
IDYA Ideaya Biosciences Inc. New 0.81% +0.81
LIVN Livanova PLC Add +258.5% 1.09% +0.79
COO The Cooper Cos Inc. Add +38.2% 2.51% +0.71
BIIB Biogen Inc. Add +67.9% 1.52% +0.67
NRIX Nurix Therapeutics Inc. Add +54.7% 0.95% +0.60
BBIO Bridgebio Pharma Inc. New 0.58% +0.58
MDT Medtronic PLC Add +44.4% 2.66% +0.50
BTSG Brightspring Health Services Add +230.0% 0.69% +0.50
GILD Gilead Sciences Inc. Add +57.4% 1.45% +0.46
DOCS Doximity Inc. Class A Add +174.1% 1.54% +0.44
GH Guardant Health Inc. Add +60.0% 0.76% +0.42
CRL Charles River Laboratories New 0.41% +0.41
IMCR Immunocore Holdings PLC-ADR Add +442.0% 0.50% +0.38
KURA Kura Oncology Inc. Add +78.0% 0.85% +0.37
OSCR Oscar Health Inc. Class A New 0.35% +0.35
KRYS Krystal Biotech Inc. Add +112.8% 0.58% +0.35
PEN Penumbra Inc. Add +53.7% 0.92% +0.34
MIRM Mirum Pharmaceuticals Inc. Add +88.9% 0.78% +0.33
NTRA Natera Inc. Add +30.6% 0.87% +0.31
ASND Ascendis Pharma A/S New 0.30% +0.30
APLS Apellis Pharmaceuticals Inc. Add +61.2% 0.88% +0.30
ALGN Align Technology Inc. Add +19.3% 1.44% +0.29
MLTX Moonlake Immunotherapeutics Add +75.8% 0.45% +0.28
PRCT Procept Biorobotics Corp. Add +56.7% 1.80% +0.26
A Agilent Technologies Inc. New 0.25% +0.25
CNTA Centessa Pharmaceuticals Ltd. New 0.23% +0.23
XENE Xenon Pharmaceuticals Inc. Add +71.6% 0.58% +0.22
ACLX Arcellx Inc. Add +104.6% 0.81% +0.22
TMO Thermo Fisher Scientific Inc. Add +12.0% 1.82% +0.21
EW Edwards Lifesciences Corp. Add +24.8% 1.54% +0.21
WST West Pharmaceutical Services New 0.18% +0.18
QURE Uniqure NV New 0.18% +0.18
CVS CVS Health Corp. Add +21.0% 2.49% +0.17
IQV Iqvia Holdings Inc. Add +35.9% 0.56% +0.15
IOVA Iovance Biotherapeutics Inc. Add +45.3% 0.41% +0.14
STE Steris PLC New 0.14% +0.14
MDGL Madrigal Pharmaceuticals Inc. Add +7.1% 1.06% +0.14
STVN Stevanato Group SPA Add +188.3% 0.28% +0.13
THC Tenet Healthcare Corp. Add +30.9% 1.42% +0.11
ADPT Adaptive Biotechnologies Add +22.2% 0.92% +0.10
ALNY Alnylam Pharmaceuticals Inc. Add +43.3% 1.70% +0.09
BMRN Biomarin Pharmaceutical Inc. Add +15.2% 1.19% +0.08
OCUL Ocular Therapeutix Inc. Add +31.2% 0.30% +0.04
ALKS Alkermes PLC Add +41.8% 0.35% +0.04

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 99$1.1BUNH, CVS, AZN, MRK, LLY
Q1 2026 86$810.5MBSX, REGN, LLY, INSM, CVS
Q4 2025 94$1.1BREGN, LLY, BSX, MDT, ISRG
Q3 2025 92$903.7MBSX, LLY, ABBV, DHR, ALHC
Q2 2025 90$791.0MLLY, BSX, VRTX, GKOS, ISRG
Q1 2025 94$870.0MUNH, LLY, VRTX, MCK, BSX
Q4 2024 92$972.9MBSX, LLY, PRCT, ISRG, REGN
Q3 2024 95$1.2BBSX, UNH, LLY, REGN, THC
Q2 2024 93$1.0BUNH, ELV, BSX, LLY, REGN
Q1 2024 84$1.1BCI, LLY, THC, BSX, ELV