Sectoral Asset Management Inc.

Name: SECTORAL ASSET MANAGEMENT INC 13F holdings, Q2 2024
Creator: SECTORAL ASSET MANAGEMENT INC
Published: 2024-08-13

Q2 2026Q1 2026Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q1 2024

In its 13F for Q2 2024 (holdings as of June 30, 2024, filed August 13, 2024), Sectoral Asset Management Inc. reported 97 stock positions worth $246.1 million. Its top holding was Eli Lilly (LLY) at 8.6% of the portfolio, followed by Lenz Therapeutics (LENZ, 7.6%) and Contineum Therapeutics Class A (CTNM, 5.7%). Compared with Q1 2024, it opened 13 new positions, sold out of 9, added to 20 and reduced 57. The biggest buy was a new position in Contineum Therapeutics Class A (CTNM) and the biggest sale Boundless Bio (BOLD, shares −20%).

Most Recent 13F: Q2 2026
Location: MONTREAL, A8
CIK: 0001274413
Portfolio Value: $246.1M (Q2 2024)
SEC Filing: 0001104659-24-088729 ↗ filed Aug 13, 2024

Holdings Value

Holdings 97 stocks · $246.1M


LLY Eli Lilly & Co.	8.62%	23,415	$21.2M	Reduce -8.8%
LENZ Lenz Therapeutics Inc.	7.62%	1,084,404	$18.7M	Add +1.5%
CTNM Contineum Therapeutics Inc. Class A	5.73%	800,887	$14.1M	New
UNH Unitedhealth Group Inc.	5.52%	26,675	$13.6M	Add +15.1%
MRK Merck & Co. Inc.	4.35%	86,500	$10.7M	No change
JNJ Johnson & Johnson	3.38%	56,850	$8.3M	Add +18.8%
ABBV Abbvie Inc.	3.13%	44,950	$7.7M	Add +27.7%
ABT Abbott Laboratories	2.80%	66,248	$6.9M	Reduce -5.7%
REGN Regeneron Pharmaceuticals	2.58%	6,040	$6.3M	Reduce -14.6%
TMO Thermo Fisher Scientific Inc.	2.36%	10,515	$5.8M	Add +5.0%
BSX Boston Scientific Corp.	2.24%	71,476	$5.5M	Reduce -17.4%
MLYS Mineralys Therapeutics Inc.	2.09%	438,748	$5.1M	Reduce -20.6%
PFE Pfizer Inc.	2.06%	181,400	$5.1M	Reduce -4.2%
GILD Gilead Sciences Inc.	1.92%	68,825	$4.7M	Add +77.8%
MDT Medtronic PLC	1.90%	59,551	$4.7M	Add +56.5%
AMGN Amgen Inc.	1.87%	14,700	$4.6M	Reduce -8.6%
DHR Danaher Corp.	1.80%	17,725	$4.4M	No change
SYK Stryker Corp.	1.78%	12,850	$4.4M	Add +94.7%
VRTX Vertex Pharmaceuticals Inc.	1.65%	8,650	$4.1M	Add +20.0%
DXCM Dexcom Inc.	1.48%	32,150	$3.6M	Reduce -0.8%
BMRN Biomarin Pharmaceutical Inc.	1.38%	41,260	$3.4M	Reduce -20.1%
IQV Iqvia Holdings Inc.	1.34%	15,600	$3.3M	Add +10.6%
ALNY Alnylam Pharmaceuticals Inc.	1.23%	12,480	$3.0M	Reduce -32.4%
ZBH Zimmer Biomet Holdings Inc.	1.18%	26,650	$2.9M	Reduce -10.4%
ARGX Argenx SE - ADR	1.14%	6,522	$2.8M	Reduce -29.9%
BOLD Boundless Bio Inc.	1.07%	682,274	$2.6M	Reduce -20.3%
MRNA Moderna Inc.	1.07%	22,110	$2.6M	Add +50.0%
PCVX Vaxcyte Inc.	1.04%	33,730	$2.5M	Add +296.8%
ICLR Icon PLC	1.02%	8,028	$2.5M	Add +1.1%
ELV Elevance Health Inc.	0.99%	4,500	$2.4M	Add +28.6%
ISRG Intuitive Surgical Inc.	0.98%	5,400	$2.4M	Reduce -11.5%
CVS CVS Health Corp.	0.94%	39,000	$2.3M	New
BNTX Biontech SE-ADR	0.89%	27,265	$2.2M	Add +673.5%
FOLD Amicus Therapeutics Inc.	0.87%	216,844	$2.2M	Reduce -1.9%
SRPT Sarepta Therapeutics Inc.	0.87%	13,496	$2.1M	Reduce -21.9%
GDRX Goodrx Holdings Inc. Class A	0.84%	265,000	$2.1M	Reduce -17.4%
SPRY Ars Pharmaceuticals Inc.	0.82%	236,937	$2.0M	Add +15.9%
PGNY Progyny Inc.	0.81%	70,000	$2.0M	Reduce -7.9%
CYTK Cytokinetics Inc.	0.81%	36,883	$2.0M	Reduce -13.4%
NARI Inari Medical Inc.	0.79%	40,500	$2.0M	Reduce -22.9%
OPCH Option Care Health Inc.	0.73%	65,000	$1.8M	Add +1.6%
HUM Humana Inc.	0.72%	4,751	$1.8M	No change
AZN Astrazeneca PLC-Spons ADR	0.69%	21,650	$1.7M	Reduce -11.4%
STVN Stevanato Group SPA	0.66%	89,000	$1.6M	New
EVH Evolent Health Inc. Class A	0.65%	84,000	$1.6M	New
PODD Insulet Corp.	0.60%	7,350	$1.5M	Reduce -59.4%
EW Edwards Lifesciences Corp.	0.59%	15,650	$1.4M	No change
ITOS Iteos Therapeutics Inc.	0.58%	96,966	$1.4M	Reduce -27.6%
BIIB Biogen Inc.	0.58%	6,137	$1.4M	Reduce -11.9%
TSBX Turnstone Biologics Corp.	0.55%	517,648	$1.4M	No change
OLMA Olema Pharmaceuticals Inc.	0.52%	118,480	$1.3M	Reduce -15.4%
BMY Bristol-Myers Squibb Co.	0.51%	30,000	$1.2M	New
RCUS Arcus Biosciences Inc.	0.49%	78,385	$1.2M	Reduce -16.3%
CI The Cigna Group	0.47%	3,500	$1.2M	New
MLTX Moonlake Immunotherapeutics	0.38%	21,428	$942K	Reduce -53.7%
BDX Becton Dickinson and Co.	0.38%	4,000	$935K	New
ARVN Arvinas Inc.	0.38%	34,830	$927K	Reduce -28.6%
COGT Cogent Biosciences Inc.	0.29%	85,600	$722K	Reduce -67.5%
ADCT Adc Therapeutics SA	0.29%	228,102	$721K	New
INSM Insmed Inc.	0.27%	9,821	$658K	Reduce -40.2%
ILMN Illumina Inc.	0.25%	5,810	$606K	Reduce -7.5%
UTHR United Therapeutics Corp.	0.24%	1,820	$580K	Reduce -29.9%
NBIX Neurocrine Biosciences Inc.	0.22%	3,935	$542K	Reduce -6.2%
INCY Incyte Corp.	0.22%	8,905	$540K	Reduce -5.3%
GPCR Structure Therapeutics Inc.	0.21%	13,365	$525K	Add +124.1%
ROIV Roivant Sciences Ltd.	0.20%	45,957	$486K	Reduce -7.1%
IONS Ionis Pharmaceuticals Inc.	0.19%	9,660	$460K	Reduce -4.4%
MEDP Medpace Holdings Inc.	0.19%	1,106	$456K	Reduce -14.3%
ITCI Intra-Cellular Therapies Inc.	0.18%	6,530	$447K	Reduce -7.8%
RPRX Royalty Pharma PLC Class A	0.18%	16,650	$439K	Reduce -14.3%
BPMC Blueprint Medicines Corp.	0.17%	3,850	$415K	Reduce -12.7%
ALKS Alkermes PLC	0.16%	16,730	$403K	Add +17.6%
APLS Apellis Pharmaceuticals Inc.	0.16%	10,460	$401K	Add +8.2%
BBIO Bridgebio Pharma Inc.	0.16%	15,535	$394K	Reduce -3.5%
ASND Ascendis Pharma A/S	0.15%	2,666	$364K	Reduce -33.5%
JAZZ Jazz Pharmaceuticals PLC	0.14%	3,334	$356K	Reduce -14.4%
SNY Sanofi-ADR	0.14%	7,330	$356K	Reduce -42.1%
ONC Beone Medicines Ltd.-ADR filed as BEIGENE LTD	0.14%	2,447	$349K	Reduce -33.7%
RDY Dr. Reddy's Laboratories-ADR	0.14%	4,500	$343K	Reduce -18.2%
MDGL Madrigal Pharmaceuticals Inc.	0.12%	1,065	$298K	Reduce -5.8%
VERA Vera Therapeutics Inc.	0.11%	7,718	$279K	Reduce -82.8%
RCKT Rocket Pharmaceuticals Inc.	0.11%	12,530	$270K	Reduce -15.4%
CRNX Crinetics Pharmaceuticals Inc.	0.11%	5,800	$260K	New
EXEL Exelixis Inc.	0.10%	11,460	$258K	Reduce -12.8%
RVMD Revolution Medicines Inc.	0.10%	6,600	$256K	Reduce -48.9%
VTRS Viatris Inc.	0.10%	22,500	$239K	New
HALO Halozyme Therapeutics Inc.	0.08%	3,815	$200K	Reduce -32.8%
ARWR Arrowhead Pharmaceuticals Inc.	0.08%	7,522	$195K	Reduce -2.1%
SMMT Summit Therapeutics Inc.	0.08%	25,000	$195K	Reduce -92.1%
BHVN Biohaven Ltd.	0.06%	3,900	$135K	New
PTCT PTC Therapeutics Inc.	0.05%	4,300	$131K	New
SRRK Scholar Rock Holding Corp.	0.05%	15,030	$125K	Reduce -2.4%
CATX Perspective Therapeutics Inc.	0.04%	11,000	$110K	New
LEGN Legend Biotech Corp.-ADR	0.04%	2,000	$89K	Reduce -33.3%
KYTX Kyverna Therapeutics Inc.	0.02%	7,000	$53K	No change
ZLAB Zai Lab Ltd.-ADR	0.01%	2,000	$35K	No change
GRAL Grail Inc.	0.00%	240	$4K	Reduce -77.1%

Portfolio Sells Q1 2024 → Q2 2024


BOLD Boundless Bio Inc.	Reduce -20.3%	1.07%	−3.72
CNC Centene Corp.	Sold out	0.00%	−1.05
EYPT Eyepoint Inc.	Sold out	0.00%	−0.75
ATEC Alphatec Holdings Inc.	Sold out	0.00%	−0.74
MLYS Mineralys Therapeutics Inc.	Reduce -20.6%	2.09%	−0.72
VERA Vera Therapeutics Inc.	Reduce -82.8%	0.11%	−0.65
SLRN Acelyrin Inc.	Sold out	0.00%	−0.65
PODD Insulet Corp.	Reduce -59.4%	0.60%	−0.62
EFTR Effector Therapeutics Inc.	Sold out	0.00%	−0.54
MLTX Moonlake Immunotherapeutics	Reduce -53.7%	0.38%	−0.53
SMMT Summit Therapeutics Inc.	Reduce -92.1%	0.08%	−0.43
ARVN Arvinas Inc.	Reduce -28.6%	0.38%	−0.41
COGT Cogent Biosciences Inc.	Reduce -67.5%	0.29%	−0.40
BMRN Biomarin Pharmaceutical Inc.	Reduce -20.1%	1.38%	−0.39
ALT Altimmune Inc.	Sold out	0.00%	−0.37
ZBH Zimmer Biomet Holdings Inc.	Reduce -10.4%	1.18%	−0.37
CYTK Cytokinetics Inc.	Reduce -13.4%	0.81%	−0.36
VSTM Verastem Inc.	Sold out	0.00%	−0.34
ABT Abbott Laboratories	Reduce -5.7%	2.80%	−0.34
PGNY Progyny Inc.	Reduce -7.9%	0.81%	−0.33
ARGX Argenx SE - ADR	Reduce -29.9%	1.14%	−0.30
DXCM Dexcom Inc.	Reduce -0.8%	1.48%	−0.29
RCUS Arcus Biosciences Inc.	Reduce -16.3%	0.49%	−0.21
NARI Inari Medical Inc.	Reduce -22.9%	0.79%	−0.20
FOLD Amicus Therapeutics Inc.	Reduce -1.9%	0.87%	−0.15
ITOS Iteos Therapeutics Inc.	Reduce -27.6%	0.58%	−0.13
OLMA Olema Pharmaceuticals Inc.	Reduce -15.4%	0.52%	−0.10
DNLI Denali Therapeutics Inc.	Sold out	0.00%	−0.10
SNY Sanofi-ADR	Reduce -42.1%	0.14%	−0.10
REGN Regeneron Pharmaceuticals	Reduce -14.6%	2.58%	−0.10
NTLA Intellia Therapeutics Inc.	Sold out	0.00%	−0.10
ILMN Illumina Inc.	Reduce -7.5%	0.25%	−0.09
BSX Boston Scientific Corp.	Reduce -17.4%	2.24%	−0.09
ASND Ascendis Pharma A/S	Reduce -33.5%	0.15%	−0.09
ONC Beone Medicines Ltd.-ADR	Reduce -33.7%	0.14%	−0.09
RVMD Revolution Medicines Inc.	Reduce -48.9%	0.10%	−0.06
SRRK Scholar Rock Holding Corp.	Reduce -2.4%	0.05%	−0.06
GDRX Goodrx Holdings Inc. Class A	Reduce -17.4%	0.84%	−0.06
RPRX Royalty Pharma PLC Class A	Reduce -14.3%	0.18%	−0.05
RCKT Rocket Pharmaceuticals Inc.	Reduce -15.4%	0.11%	−0.05
JAZZ Jazz Pharmaceuticals PLC	Reduce -14.4%	0.14%	−0.04
BBIO Bridgebio Pharma Inc.	Reduce -3.5%	0.16%	−0.04
LEGN Legend Biotech Corp.-ADR	Reduce -33.3%	0.04%	−0.03
MEDP Medpace Holdings Inc.	Reduce -14.3%	0.19%	−0.02
RDY Dr. Reddy's Laboratories-ADR	Reduce -18.2%	0.14%	−0.02
EXEL Exelixis Inc.	Reduce -12.8%	0.10%	−0.02
SRPT Sarepta Therapeutics Inc.	Reduce -21.9%	0.87%	−0.01
BIIB Biogen Inc.	Reduce -11.9%	0.58%	−0.01
ITCI Intra-Cellular Therapies Inc.	Reduce -7.8%	0.18%	−0.01
HALO Halozyme Therapeutics Inc.	Reduce -32.8%	0.08%	−0.01

Portfolio Buys Q1 2024 → Q2 2024


CTNM Contineum Therapeutics Inc. Class A	New	5.73%	+5.73
UNH Unitedhealth Group Inc.	Add +15.1%	5.52%	+1.01
CVS CVS Health Corp.	New	0.94%	+0.94
SYK Stryker Corp.	Add +94.7%	1.78%	+0.85
PCVX Vaxcyte Inc.	Add +296.8%	1.04%	+0.81
GILD Gilead Sciences Inc.	Add +77.8%	1.92%	+0.80
BNTX Biontech SE-ADR	Add +673.5%	0.89%	+0.76
STVN Stevanato Group SPA	New	0.66%	+0.66
EVH Evolent Health Inc. Class A	New	0.65%	+0.65
ABBV Abbvie Inc.	Add +27.7%	3.13%	+0.61
MDT Medtronic PLC	Add +56.5%	1.90%	+0.60
BMY Bristol-Myers Squibb Co.	New	0.51%	+0.51
CI The Cigna Group	New	0.47%	+0.47
VRTX Vertex Pharmaceuticals Inc.	Add +20.0%	1.65%	+0.46
MRNA Moderna Inc.	Add +50.0%	1.07%	+0.45
JNJ Johnson & Johnson	Add +18.8%	3.38%	+0.40
BDX Becton Dickinson and Co.	New	0.38%	+0.38
ADCT Adc Therapeutics SA	New	0.29%	+0.29
ELV Elevance Health Inc.	Add +28.6%	0.99%	+0.28
GPCR Structure Therapeutics Inc.	Add +124.1%	0.21%	+0.11
CRNX Crinetics Pharmaceuticals Inc.	New	0.11%	+0.11
VTRS Viatris Inc.	New	0.10%	+0.10
TMO Thermo Fisher Scientific Inc.	Add +5.0%	2.36%	+0.07
BHVN Biohaven Ltd.	New	0.06%	+0.06
PTCT PTC Therapeutics Inc.	New	0.05%	+0.05
CATX Perspective Therapeutics Inc.	New	0.04%	+0.04
ALKS Alkermes PLC	Add +17.6%	0.16%	+0.01
SPRY Ars Pharmaceuticals Inc.	Add +15.9%	0.82%	−0.00
ICLR Icon PLC	Add +1.1%	1.02%	−0.03
APLS Apellis Pharmaceuticals Inc.	Add +8.2%	0.16%	−0.06
IQV Iqvia Holdings Inc.	Add +10.6%	1.34%	−0.06
OPCH Option Care Health Inc.	Add +1.6%	0.73%	−0.11
LENZ Lenz Therapeutics Inc.	Add +1.5%	7.62%	−1.76

All Filings

Quarter	Positions	13F Reported Value	Top Holdings
Q2 2026	82	$143.3M	CTNM, SI, LLY, UNH, JNJ
Q1 2026	77	$120.7M	EVMN, CTNM, SI, LLY, JNJ
Q4 2025	74	$124.8M	EVMN, CTNM, LLY, SI, UNH
Q3 2025	82	$162.0M	CTNM, LLY, GPCR, ANAB, SI
Q2 2025	94	$151.5M	LENZ, LLY, UNH, MLYS, CTNM
Q1 2025	84	$128.5M	LENZ, LLY, UNH, MLYS, CTNM
Q4 2024	86	$149.8M	LENZ, CTNM, LLY, UNH, GILD
Q3 2024	90	$169.3M	LENZ, CTNM, LLY, UNH, GILD
Q2 2024	97	$246.1M	LLY, LENZ, CTNM, UNH, MRK
Q1 2024	92	$254.4M	LENZ, LLY, BOLD, UNH, MRK