Tri Locum Partners LP

In its 13F for Q1 2025 (holdings as of March 31, 2025, filed May 14, 2025), Tri Locum Partners LP reported 22 stock positions worth $194.9 million. Its top holding was Cigna (CI) at 12.5% of the portfolio, followed by McKesson (MCK, 9.3%) and Soleno Therapeutics (SLNO, 8.6%). Compared with Q4 2024, it opened 9 new positions, sold out of 15, added to 2 and reduced 10. The biggest buy was Cigna (CI, shares +81%) and the biggest sale an exit from Zimmer Biomet (ZBH).

Most Recent 13F
Q2 2026
Location
NEW YORK, NY
CIK
0001826434
Portfolio Value
$194.9M (Q1 2025)
SEC Filing
0001826434-25-000004 ↗ filed May 14, 2025

Holdings Value

0$200.0M$400.0M$600.0M$800.0M$1.0B Q1 2024: $288.4M Q1 2024 Q2 2024: $395.5M Q2 2024 Q3 2024: $417.4M Q3 2024 Q4 2024: $482.7M Q4 2024 Q1 2025: $194.9M $194.9M Q1 2025 Q2 2025: $329.5M Q2 2025 Q3 2025: $435.1M Q3 2025 Q4 2025: $770.1M Q4 2025 Q1 2026: $712.5M Q1 2026 Q2 2026: $813.2M Q2 2026

Holdings 22 stocks · $194.9M

CI The Cigna Group 12.48% 73,905 $24.3M Add +81.1%
MCK McKesson Corp. 9.30% 26,944 $18.1M New
SLNO Soleno Therapeutics Inc. 8.61% 234,920 $16.8M New
TEVA Teva Pharmaceutical-SP ADR 8.37% 1,061,008 $16.3M Reduce -56.2%
INSP Inspire Medical Systems Inc. 6.44% 78,812 $12.6M Reduce -47.7%
MDGL Madrigal Pharmaceuticals Inc. 6.44% 37,869 $12.5M Reduce -20.2%
AXSM Axsome Therapeutics Inc. 6.06% 101,240 $11.8M Reduce -59.5%
ARGX Argenx SE - ADR 5.42% 17,844 $10.6M Reduce -69.4%
GILD Gilead Sciences Inc. 5.14% 89,453 $10.0M New
ILMN Illumina Inc. 4.91% 120,729 $9.6M New
INSM Insmed Inc. 3.99% 101,859 $7.8M New
NUVL Nuvalent Inc. Class A 3.49% 95,825 $6.8M New
MRUS Merus NV 3.39% 156,915 $6.6M Reduce -54.8%
WGS Genedx Holdings Corp. 2.64% 58,145 $5.1M Reduce -54.4%
ASND Ascendis Pharma A/S 2.58% 32,325 $5.0M New
BPMC Blueprint Medicines Corp. 2.27% 50,000 $4.4M New
EOLS Evolus Inc. 1.99% 321,802 $3.9M Reduce -56.7%
VERA Vera Therapeutics Inc. 1.85% 150,207 $3.6M New
STVN Stevanato Group SPA 1.84% 175,681 $3.6M Reduce -84.3%
PRAX Praxis Precision Medicines I 1.63% 83,659 $3.2M Add +124.5%
KRRO Korro Bio Inc. 1.15% 128,381 $2.2M Reduce -11.0%
FEMY Femasys Inc. 0.02% 30,606 $38K No change

Portfolio Sells Q4 2024 → Q1 2025

ZBH Zimmer Biomet Holdings Inc. Sold out 0.00% −8.07
NTRA Natera Inc. Sold out 0.00% −6.65
VRNA Verona Pharma Ltd. Sold out 0.00% −4.37
AVDL Avadel Pharmaceuticals Ltd. Sold out 0.00% −4.22
BMY Bristol-Myers Squibb Co. Sold out 0.00% −4.16
JAZZ Jazz Pharmaceuticals PLC Sold out 0.00% −4.13
IDXX Idexx Laboratories Inc. Sold out 0.00% −3.85
NVO Novo-Nordisk A/S-Spons ADR Sold out 0.00% −3.74
STVN Stevanato Group SPA Reduce -84.3% 1.84% −3.22
UNH Unitedhealth Group Inc. Sold out 0.00% −2.95
TEVA Teva Pharmaceutical-SP ADR Reduce -56.2% 8.37% −2.70
JANX Janux Therapeutics Inc. Sold out 0.00% −2.62
LEGN Legend Biotech Corp.-ADR Sold out 0.00% −2.62
ARGX Argenx SE - ADR Reduce -69.4% 5.42% −2.00
GERN Geron Corp. Sold out 0.00% −1.81
MIND MEDICINE MINDMED INC Sold out 0.00% −1.18
BHVN Biohaven Ltd. Sold out 0.00% −1.08
LIVN Livanova PLC Sold out 0.00% −0.96
KRRO Korro Bio Inc. Reduce -11.0% 1.15% +0.01
EOLS Evolus Inc. Reduce -56.7% 1.99% +0.29
MRUS Merus NV Reduce -54.8% 3.39% +0.36
WGS Genedx Holdings Corp. Reduce -54.4% 2.64% +0.61
INSP Inspire Medical Systems Inc. Reduce -47.7% 6.44% +0.65
AXSM Axsome Therapeutics Inc. Reduce -59.5% 6.06% +1.68
MDGL Madrigal Pharmaceuticals Inc. Reduce -20.2% 6.44% +3.40

Portfolio Buys Q4 2024 → Q1 2025

CI The Cigna Group Add +81.1% 12.48% +10.14
MCK McKesson Corp. New 9.30% +9.30
SLNO Soleno Therapeutics Inc. New 8.61% +8.61
GILD Gilead Sciences Inc. New 5.14% +5.14
ILMN Illumina Inc. New 4.91% +4.91
INSM Insmed Inc. New 3.99% +3.99
NUVL Nuvalent Inc. Class A New 3.49% +3.49
ASND Ascendis Pharma A/S New 2.58% +2.58
BPMC Blueprint Medicines Corp. New 2.27% +2.27
VERA Vera Therapeutics Inc. New 1.85% +1.85
PRAX Praxis Precision Medicines I Add +124.5% 1.63% +1.03

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 19$813.2MJNJ, VRTX, LLY, ASND, DXCM
Q1 2026 17$712.5MJNJ, ISRG, TMO, ASND, VRTX
Q4 2025 15$770.1MJNJ, DHR, LLY, UTHR, ASND
Q3 2025 18$435.1MJNJ, UTHR, MRK, AXSM, ASND
Q2 2025 23$329.5MTEVA, MDGL, ALNY, ARGX, ASND
Q1 2025 22$194.9MCI, MCK, SLNO, TEVA, INSP
Q4 2024 28$482.7MTEVA, ZBH, ARGX, NTRA, INSP
Q3 2024 20$417.4MPFE, TEVA, NTRA, STVN, ARGX
Q2 2024 25$395.5MTEVA, ARGX, ASND, AMGN, NTRA
Q1 2024 27$288.4MTEVA, AVDL, SILK, NTRA, ASND