Tri Locum Partners LP

In its 13F for Q1 2026 (holdings as of March 31, 2026, filed May 18, 2026), Tri Locum Partners LP reported 17 stock positions worth $712.5 million. Its top holding was Johnson & Johnson (JNJ) at 14.2% of the portfolio, followed by Intuitive Surgical (ISRG, 9.9%) and Thermo Fisher Scientific (TMO, 9.1%). Compared with Q4 2025, it opened 6 new positions, sold out of 4, added to 3 and reduced 8. The biggest buy was a new position in Intuitive Surgical (ISRG) and the biggest sale an exit from Danaher (DHR).

Most Recent 13F
Q2 2026
Location
NEW YORK, NY
CIK
0001826434
Portfolio Value
$712.5M (Q1 2026)
SEC Filing
0001826434-26-000004 ↗ filed May 18, 2026

Holdings Value

0$200.0M$400.0M$600.0M$800.0M$1.0B Q1 2024: $288.4M Q1 2024 Q2 2024: $395.5M Q2 2024 Q3 2024: $417.4M Q3 2024 Q4 2024: $482.7M Q4 2024 Q1 2025: $194.9M Q1 2025 Q2 2025: $329.5M Q2 2025 Q3 2025: $435.1M Q3 2025 Q4 2025: $770.1M Q4 2025 Q1 2026: $712.5M $712.5M Q1 2026 Q2 2026: $813.2M Q2 2026

Holdings 17 stocks · $712.5M

JNJ Johnson & Johnson 14.22% 414,503 $101.3M Reduce -31.3%
ISRG Intuitive Surgical Inc. 9.91% 153,250 $70.6M New
TMO Thermo Fisher Scientific Inc. 9.13% 132,413 $65.1M New
ASND Ascendis Pharma A/S 8.20% 255,332 $58.4M Reduce -3.6%
VRTX Vertex Pharmaceuticals Inc. 8.10% 129,314 $57.7M New
LLY Eli Lilly & Co. 7.98% 61,795 $56.8M Reduce -2.4%
MDGL Madrigal Pharmaceuticals Inc. 7.59% 103,288 $54.1M Add +20.1%
DXCM Dexcom Inc. 6.15% 698,158 $43.8M Add +65.6%
UTHR United Therapeutics Corp. 5.86% 70,370 $41.7M Reduce -41.8%
NUVL Nuvalent Inc. Class A 4.44% 308,506 $31.6M Add +0.4%
TEVA Teva Pharmaceutical-SP ADR 4.32% 1,021,008 $30.8M Reduce -28.9%
JAZZ Jazz Pharmaceuticals PLC 4.21% 158,663 $30.0M New
ARGX Argenx SE - ADR 3.24% 31,635 $23.1M Reduce -16.0%
TARS Tarsus Pharmaceuticals Inc. 2.49% 252,588 $17.7M New
DNTH Dianthus Therapeutics Inc. 1.71% 145,543 $12.2M Reduce -76.6%
AXSM Axsome Therapeutics Inc. 1.47% 62,116 $10.5M Reduce -69.2%
DFTX Definium Therapeutics Inc. 0.98% 369,588 $7.0M New

Portfolio Sells Q4 2025 → Q1 2026

DHR Danaher Corp. Sold out 0.00% −10.31
BSX Boston Scientific Corp. Sold out 0.00% −6.44
IONS Ionis Pharmaceuticals Inc. Sold out 0.00% −5.72
VERA Vera Therapeutics Inc. Sold out 0.00% −5.30
AXSM Axsome Therapeutics Inc. Reduce -69.2% 1.47% −3.31
JNJ Johnson & Johnson Reduce -31.3% 14.22% −1.99
UTHR United Therapeutics Corp. Reduce -41.8% 5.86% −1.79
DNTH Dianthus Therapeutics Inc. Reduce -76.6% 1.71% −1.62
TEVA Teva Pharmaceutical-SP ADR Reduce -28.9% 4.32% −1.50
ARGX Argenx SE - ADR Reduce -16.0% 3.24% −0.87
LLY Eli Lilly & Co. Reduce -2.4% 7.98% −0.85
ASND Ascendis Pharma A/S Reduce -3.6% 8.20% +0.86

Portfolio Buys Q4 2025 → Q1 2026

ISRG Intuitive Surgical Inc. New 9.91% +9.91
TMO Thermo Fisher Scientific Inc. New 9.13% +9.13
VRTX Vertex Pharmaceuticals Inc. New 8.10% +8.10
JAZZ Jazz Pharmaceuticals PLC New 4.21% +4.21
DXCM Dexcom Inc. Add +65.6% 6.15% +2.52
TARS Tarsus Pharmaceuticals Inc. New 2.49% +2.49
MDGL Madrigal Pharmaceuticals Inc. Add +20.1% 7.59% +1.08
DFTX Definium Therapeutics Inc. New 0.98% +0.98
NUVL Nuvalent Inc. Class A Add +0.4% 4.44% +0.42

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 19$813.2MJNJ, VRTX, LLY, ASND, DXCM
Q1 2026 17$712.5MJNJ, ISRG, TMO, ASND, VRTX
Q4 2025 15$770.1MJNJ, DHR, LLY, UTHR, ASND
Q3 2025 18$435.1MJNJ, UTHR, MRK, AXSM, ASND
Q2 2025 23$329.5MTEVA, MDGL, ALNY, ARGX, ASND
Q1 2025 22$194.9MCI, MCK, SLNO, TEVA, INSP
Q4 2024 28$482.7MTEVA, ZBH, ARGX, NTRA, INSP
Q3 2024 20$417.4MPFE, TEVA, NTRA, STVN, ARGX
Q2 2024 25$395.5MTEVA, ARGX, ASND, AMGN, NTRA
Q1 2024 27$288.4MTEVA, AVDL, SILK, NTRA, ASND