Tri Locum Partners LP

In its 13F for Q2 2025 (holdings as of June 30, 2025, filed August 14, 2025), Tri Locum Partners LP reported 23 stock positions worth $329.5 million. Its top holding was Teva Pharmaceutical-SP ADR (TEVA) at 10.4% of the portfolio, followed by Madrigal Pharmaceuticals (MDGL, 9.0%) and Alnylam Pharmaceuticals (ALNY, 8.9%). Compared with Q1 2025, it opened 9 new positions, sold out of 8, added to 11 and reduced 2. The biggest buy was a new position in Alnylam Pharmaceuticals (ALNY) and the biggest sale an exit from Cigna (CI).

Most Recent 13F
Q2 2026
Location
NEW YORK, NY
CIK
0001826434
Portfolio Value
$329.5M (Q2 2025)
SEC Filing
0001826434-25-000006 ↗ filed Aug 14, 2025

Holdings Value

0$200.0M$400.0M$600.0M$800.0M$1.0B Q1 2024: $288.4M Q1 2024 Q2 2024: $395.5M Q2 2024 Q3 2024: $417.4M Q3 2024 Q4 2024: $482.7M Q4 2024 Q1 2025: $194.9M Q1 2025 Q2 2025: $329.5M $329.5M Q2 2025 Q3 2025: $435.1M Q3 2025 Q4 2025: $770.1M Q4 2025 Q1 2026: $712.5M Q1 2026 Q2 2026: $813.2M Q2 2026

Holdings 23 stocks · $329.5M

TEVA Teva Pharmaceutical-SP ADR 10.41% 2,046,846 $34.3M Add +92.9%
MDGL Madrigal Pharmaceuticals Inc. 8.98% 97,765 $29.6M Add +158.2%
ALNY Alnylam Pharmaceuticals Inc. 8.86% 89,525 $29.2M New
ARGX Argenx SE - ADR 8.00% 47,793 $26.3M Add +167.8%
ASND Ascendis Pharma A/S 7.73% 147,642 $25.5M Add +356.7%
SLNO Soleno Therapeutics Inc. 7.34% 288,880 $24.2M Add +23.0%
VRNA Verona Pharma Ltd. 6.22% 216,578 $20.5M New
INSP Inspire Medical Systems Inc. 5.88% 149,244 $19.4M Add +89.4%
UNH Unitedhealth Group Inc. 5.74% 60,584 $18.9M New
AXSM Axsome Therapeutics Inc. 5.00% 157,861 $16.5M Add +55.9%
EOLS Evolus Inc. 3.46% 1,239,031 $11.4M Add +285.0%
ABBV Abbvie Inc. 3.14% 55,661 $10.3M New
VERA Vera Therapeutics Inc. 2.95% 413,114 $9.7M Add +175.0%
AVDL Avadel Pharmaceuticals Ltd. 2.72% 1,014,456 $9.0M New
PRAX Praxis Precision Medicines I 2.49% 195,432 $8.2M Add +133.6%
TARS Tarsus Pharmaceuticals Inc. 2.18% 177,656 $7.2M New
ISRG Intuitive Surgical Inc. 2.11% 12,824 $7.0M New
LEGN Legend Biotech Corp.-ADR 1.87% 173,260 $6.1M New
NUVL Nuvalent Inc. Class A 1.76% 75,973 $5.8M Reduce -20.7%
BHVN Biohaven Ltd. 1.16% 271,367 $3.8M New
KRRO Korro Bio Inc. 1.06% 139,493 $3.5M Add +8.7%
WGS Genedx Holdings Corp. 0.92% 32,931 $3.0M Reduce -43.4%
FEMY Femasys Inc. 0.01% 30,606 $30K No change

Portfolio Sells Q1 2025 → Q2 2025

CI The Cigna Group Sold out 0.00% −12.48
MCK McKesson Corp. Sold out 0.00% −9.30
GILD Gilead Sciences Inc. Sold out 0.00% −5.14
ILMN Illumina Inc. Sold out 0.00% −4.91
INSM Insmed Inc. Sold out 0.00% −3.99
MRUS Merus NV Sold out 0.00% −3.39
BPMC Blueprint Medicines Corp. Sold out 0.00% −2.27
STVN Stevanato Group SPA Sold out 0.00% −1.84
NUVL Nuvalent Inc. Class A Reduce -20.7% 1.76% −1.73
WGS Genedx Holdings Corp. Reduce -43.4% 0.92% −1.72

Portfolio Buys Q1 2025 → Q2 2025

ALNY Alnylam Pharmaceuticals Inc. New 8.86% +8.86
VRNA Verona Pharma Ltd. New 6.22% +6.22
UNH Unitedhealth Group Inc. New 5.74% +5.74
ASND Ascendis Pharma A/S Add +356.7% 7.73% +5.15
ABBV Abbvie Inc. New 3.14% +3.14
AVDL Avadel Pharmaceuticals Ltd. New 2.72% +2.72
ARGX Argenx SE - ADR Add +167.8% 8.00% +2.58
MDGL Madrigal Pharmaceuticals Inc. Add +158.2% 8.98% +2.54
TARS Tarsus Pharmaceuticals Inc. New 2.18% +2.18
ISRG Intuitive Surgical Inc. New 2.11% +2.11
TEVA Teva Pharmaceutical-SP ADR Add +92.9% 10.41% +2.04
LEGN Legend Biotech Corp.-ADR New 1.87% +1.87
EOLS Evolus Inc. Add +285.0% 3.46% +1.48
BHVN Biohaven Ltd. New 1.16% +1.16
VERA Vera Therapeutics Inc. Add +175.0% 2.95% +1.10
PRAX Praxis Precision Medicines I Add +133.6% 2.49% +0.87
KRRO Korro Bio Inc. Add +8.7% 1.06% −0.09
INSP Inspire Medical Systems Inc. Add +89.4% 5.88% −0.56
AXSM Axsome Therapeutics Inc. Add +55.9% 5.00% −1.06
SLNO Soleno Therapeutics Inc. Add +23.0% 7.34% −1.27

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 19$813.2MJNJ, VRTX, LLY, ASND, DXCM
Q1 2026 17$712.5MJNJ, ISRG, TMO, ASND, VRTX
Q4 2025 15$770.1MJNJ, DHR, LLY, UTHR, ASND
Q3 2025 18$435.1MJNJ, UTHR, MRK, AXSM, ASND
Q2 2025 23$329.5MTEVA, MDGL, ALNY, ARGX, ASND
Q1 2025 22$194.9MCI, MCK, SLNO, TEVA, INSP
Q4 2024 28$482.7MTEVA, ZBH, ARGX, NTRA, INSP
Q3 2024 20$417.4MPFE, TEVA, NTRA, STVN, ARGX
Q2 2024 25$395.5MTEVA, ARGX, ASND, AMGN, NTRA
Q1 2024 27$288.4MTEVA, AVDL, SILK, NTRA, ASND