Tri Locum Partners LP

In its 13F for Q1 2024 (holdings as of March 31, 2024, filed May 15, 2024), Tri Locum Partners LP reported 27 stock positions worth $288.4 million. Its top holding was Teva Pharmaceutical-SP ADR (TEVA) at 10.8% of the portfolio, followed by Avadel Pharmaceuticals plc (AVDL, 7.0%) and Silk Road Medical (SILK, 6.9%). Compared with Q4 2023, it opened 13 new positions, sold out of 9, added to 8 and reduced 6. The biggest buy was a new position in Silk Road Medical (SILK) and the biggest sale an exit from Abbvie (ABBV).

Most Recent 13F
Q2 2026
Location
NEW YORK, NY
CIK
0001826434
Portfolio Value
$288.4M (Q1 2024)
SEC Filing
0001826434-24-000004 ↗ filed May 15, 2024

Holdings Value

0$200.0M$400.0M$600.0M$800.0M$1.0B Q1 2024: $288.4M $288.4M Q1 2024 Q2 2024: $395.5M Q2 2024 Q3 2024: $417.4M Q3 2024 Q4 2024: $482.7M Q4 2024 Q1 2025: $194.9M Q1 2025 Q2 2025: $329.5M Q2 2025 Q3 2025: $435.1M Q3 2025 Q4 2025: $770.1M Q4 2025 Q1 2026: $712.5M Q1 2026 Q2 2026: $813.2M Q2 2026

Holdings 27 stocks · $288.4M

TEVA Teva Pharmaceutical-SP ADR 10.84% 2,216,188 $31.3M Add +23.5%
AVDL Avadel Pharmaceuticals plc 6.97% 1,189,511 $20.1M Add +41.6%
SILK Silk Road Medical Inc. filed as SILK RD MED INC 6.88% 1,083,605 $19.9M New
NTRA Natera Inc. 6.03% 190,114 $17.4M Add +34.0%
ASND Ascendis Pharma A/S 5.91% 112,670 $17.0M Add +13.2%
LEGN Legend Biotech Corp.-ADR 5.52% 283,773 $15.9M Add +177.6%
MRK Merck & Co. Inc. 5.45% 119,200 $15.7M New
VRTX Vertex Pharmaceuticals Inc. 5.16% 35,598 $14.9M New
MDGL Madrigal Pharmaceuticals Inc. 4.94% 53,355 $14.2M Add +109.0%
BAX Baxter International Inc. 4.71% 317,566 $13.6M New
MRUS Merus NV 4.47% 286,322 $12.9M New
TNDM Tandem Diabetes Care Inc. 4.01% 326,506 $11.6M New
ARGX Argenx SE - ADR 3.82% 27,981 $11.0M Add +15.7%
XENE Xenon Pharmaceuticals Inc. 3.10% 207,465 $8.9M Reduce -8.0%
REGN Regeneron Pharmaceuticals 2.86% 8,567 $8.2M Reduce -46.5%
AXSM Axsome Therapeutics Inc. 2.84% 102,711 $8.2M Reduce -21.4%
PRAX Praxis Precision Medicines I 2.25% 106,494 $6.5M Reduce -57.2%
EXAS Exact Sciences Corp. 2.16% 90,000 $6.2M New
LYRA Lyra Therapeutics Inc. 2.11% 978,793 $6.1M New
ATXS Astria Therapeutics Inc. 1.80% 369,549 $5.2M Reduce -31.9%
INSP Inspire Medical Systems Inc. 1.76% 23,566 $5.1M New
ALPN Alpine Immune Sciences Inc. 1.66% 120,687 $4.8M New
ARCT Arcturus Therapeutics Holdin 1.63% 138,927 $4.7M Add +25.8%
ARQT Arcutis Biotherapeutics Inc. 1.55% 449,694 $4.5M New
MIND MEDICINE MINDMED INC 1.24% 379,596 $3.6M New
CATX Perspective Therapeutics Inc. 0.32% 780,303 $929K New
FEMY Femasys Inc. 0.02% 30,606 $47K Reduce -15.3%

Portfolio Sells Q4 2023 → Q1 2024

ABBV Abbvie Inc. Sold out 0.00% −12.77
GEHC GE Healthcare Technology Sold out 0.00% −6.52
BIIB Biogen Inc. Sold out 0.00% −5.82
CTLT Catalent Inc. Sold out 0.00% −5.77
REGN Regeneron Pharmaceuticals Reduce -46.5% 2.86% −4.04
VRNA Verona Pharma Ltd. Sold out 0.00% −2.86
AXSM Axsome Therapeutics Inc. Reduce -21.4% 2.84% −2.27
XENE Xenon Pharmaceuticals Inc. Reduce -8.0% 3.10% −2.00
AZN Astrazeneca PLC-Spons ADR Sold out 0.00% −1.94
SRRK Scholar Rock Holding Corp. Sold out 0.00% −1.91
IMTX Immatics NV Sold out 0.00% −1.42
MLTX Moonlake Immunotherapeutics Sold out 0.00% −1.41
PRAX Praxis Precision Medicines I Reduce -57.2% 2.25% −0.47
ATXS Astria Therapeutics Inc. Reduce -31.9% 1.80% −0.24
FEMY Femasys Inc. Reduce -15.3% 0.02% −0.00

Portfolio Buys Q4 2023 → Q1 2024

SILK Silk Road Medical Inc. New 6.88% +6.88
MRK Merck & Co. Inc. New 5.45% +5.45
VRTX Vertex Pharmaceuticals Inc. New 5.16% +5.16
BAX Baxter International Inc. New 4.71% +4.71
MRUS Merus NV New 4.47% +4.47
TNDM Tandem Diabetes Care Inc. New 4.01% +4.01
LEGN Legend Biotech Corp.-ADR Add +177.6% 5.52% +2.50
EXAS Exact Sciences Corp. New 2.16% +2.16
LYRA Lyra Therapeutics Inc. New 2.11% +2.11
MDGL Madrigal Pharmaceuticals Inc. Add +109.0% 4.94% +2.04
INSP Inspire Medical Systems Inc. New 1.76% +1.76
NTRA Natera Inc. Add +34.0% 6.03% +1.67
ALPN Alpine Immune Sciences Inc. New 1.66% +1.66
TEVA Teva Pharmaceutical-SP ADR Add +23.5% 10.84% +1.65
ARQT Arcutis Biotherapeutics Inc. New 1.55% +1.55
MIND MEDICINE MINDMED INC New 1.24% +1.24
AVDL Avadel Pharmaceuticals plc Add +41.6% 6.97% +1.15
CATX Perspective Therapeutics Inc. New 0.32% +0.32
ARCT Arcturus Therapeutics Holdin Add +25.8% 1.63% −0.08
ASND Ascendis Pharma A/S Add +13.2% 5.91% −0.25
ARGX Argenx SE - ADR Add +15.7% 3.82% −0.70

Options Activity Q4 2023 → Q1 2024

KVUE Kenvue Inc. put Sold out 698,800 $15.0Mbefore exit

Calls and puts are listed by the shares they cover; their value is not part of the stock holdings above.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 19$813.2MJNJ, VRTX, LLY, ASND, DXCM
Q1 2026 17$712.5MJNJ, ISRG, TMO, ASND, VRTX
Q4 2025 15$770.1MJNJ, DHR, LLY, UTHR, ASND
Q3 2025 18$435.1MJNJ, UTHR, MRK, AXSM, ASND
Q2 2025 23$329.5MTEVA, MDGL, ALNY, ARGX, ASND
Q1 2025 22$194.9MCI, MCK, SLNO, TEVA, INSP
Q4 2024 28$482.7MTEVA, ZBH, ARGX, NTRA, INSP
Q3 2024 20$417.4MPFE, TEVA, NTRA, STVN, ARGX
Q2 2024 25$395.5MTEVA, ARGX, ASND, AMGN, NTRA
Q1 2024 27$288.4MTEVA, AVDL, SILK, NTRA, ASND