Vestal Point Capital, LP

In its 13F for Q1 2024 (holdings as of March 31, 2024, filed May 14, 2024), Vestal Point Capital, LP reported 58 stock positions worth $1.2 billion. Its top holding was Cytokinetics (CYTK) at 12.5% of the portfolio, followed by Jazz Pharmaceuticals (JAZZ, 11.0%) and Neurocrine Biosciences (NBIX, 8.1%). Compared with Q4 2023, it opened 29 new positions, sold out of 19, added to 17 and reduced 10. The biggest buy was Cytokinetics (CYTK, shares +4200%) and the biggest sale an exit from Inhibrx.

Most Recent 13F
Q2 2026
Location
NEW YORK, NY
CIK
0001974915
Portfolio Value
$1.2B (Q1 2024)
SEC Filing
0001974915-24-000005 ↗ filed May 14, 2024

Holdings Value

0$1.0B$2.0B$3.0B$4.0B$5.0B Q1 2024: $1.2B $1.2B Q1 2024 Q2 2024: $1.3B Q2 2024 Q3 2024: $1.3B Q3 2024 Q4 2024: $1.7B Q4 2024 Q1 2025: $1.4B Q1 2025 Q2 2025: $1.9B Q2 2025 Q3 2025: $2.2B Q3 2025 Q4 2025: $2.7B Q4 2025 Q1 2026: $3.6B Q1 2026 Q2 2026: $4.3B Q2 2026

Holdings 58 stocks · $1.2B

CYTK Cytokinetics Inc. 12.47% 2,150,000 $150.7M Add +4200.0%
JAZZ Jazz Pharmaceuticals PLC 10.95% 1,100,000 $132.5M Add +51.7%
NBIX Neurocrine Biosciences Inc. 8.10% 710,000 $97.9M Reduce -11.3%
ASND Ascendis Pharma A/S 6.56% 525,000 $79.4M Reduce -16.0%
GMED Globus Medical Inc. Class A 4.44% 1,000,000 $53.6M Add +25.0%
SLNO Soleno Therapeutics Inc. 4.42% 1,250,000 $53.5M Reduce -3.9%
ALNY Alnylam Pharmaceuticals Inc. 4.33% 350,000 $52.3M Add +900.0%
ONC Beone Medicines Ltd.-ADR filed as BEIGENE LTD 4.20% 325,000 $50.8M New
NARI Inari Medical Inc. 3.17% 800,000 $38.4M New
APLT Applied Therapeutics Inc. 2.87% 5,110,000 $34.7M Add +23.0%
LQDA Liquidia Corp. 2.44% 2,000,000 $29.5M Add +95.1%
ALXO Alx Oncology Holdings Inc. 2.41% 2,610,000 $29.1M Add +57.7%
AZN Astrazeneca PLC-Spons ADR 2.24% 400,000 $27.1M Add +60.0%
QURE Uniqure NV 2.03% 4,725,000 $24.6M Add +20.4%
INSM Insmed Inc. 1.68% 750,000 $20.3M Reduce -16.7%
ARGX Argenx SE - ADR 1.63% 50,000 $19.7M New
XENE Xenon Pharmaceuticals Inc. 1.42% 400,000 $17.2M Add +128.6%
TGTX TG Therapeutics Inc. 1.32% 1,050,000 $16.0M New
ATXS Astria Therapeutics Inc. 1.28% 1,100,000 $15.5M New
BMRN Biomarin Pharmaceutical Inc. 1.26% 175,000 $15.3M New
ALPN Alpine Immune Sciences Inc. 1.15% 350,000 $13.9M New
SLDB Solid Biosciences Inc. 1.14% 1,035,000 $13.8M Add +2936.5%
DNTH Dianthus Therapeutics Inc. 1.13% 455,000 $13.7M Add +237.0%
APLS Apellis Pharmaceuticals Inc. 1.09% 225,000 $13.2M New
SRPT Sarepta Therapeutics Inc. 1.07% 100,000 $12.9M New
PRAX Praxis Precision Medicines I 1.06% 210,000 $12.8M New
IMTX Immatics NV 1.04% 1,200,000 $12.6M Reduce -42.9%
INCY Incyte Corp. 0.94% 200,000 $11.4M New
MGNX Macrogenics Inc. 0.88% 725,000 $10.7M New
AGIO Agios Pharmaceuticals Inc. 0.79% 325,000 $9.5M New
SWAV Shockwave Medical Inc. 0.67% 25,000 $8.1M New
KRYS Krystal Biotech Inc. 0.66% 45,000 $8.0M New
KALV Kalvista Pharmaceuticals Inc. 0.64% 655,000 $7.8M New
GERN Geron Corp. 0.60% 2,200,000 $7.3M New
ACLX Arcellx Inc. 0.58% 100,000 $7.0M Add +66.7%
EXAS Exact Sciences Corp. 0.57% 100,000 $6.9M New
FULC Fulcrum Therapeutics Inc. 0.54% 695,000 $6.6M Reduce -32.2%
VKTX Viking Therapeutics Inc. 0.51% 75,000 $6.2M New
PASG Passage Bio Inc. 0.50% 4,500,000 $6.1M New
ALLO Allogene Therapeutics Inc. 0.50% 1,350,000 $6.0M New
FATE Fate Therapeutics Inc. 0.49% 800,000 $5.9M Reduce -38.0%
VYGR Voyager Therapeutics Inc. 0.46% 600,000 $5.6M New
RLMD Relmada Therapeutics Inc. 0.46% 1,200,000 $5.6M Add +943.5%
BIO Bio-Rad Laboratories-A 0.43% 15,000 $5.2M New
RARE Ultragenyx Pharmaceutical Inc. 0.42% 110,000 $5.1M New
LYRA Lyra Therapeutics Inc. 0.41% 800,000 $5.0M Reduce -73.3%
LKFT Lakefront Biotherapeutic-ADR filed as GALAPAGOS NV 0.35% 130,000 $4.2M No change
ANRO Alto Neuroscience Inc. 0.32% 250,000 $3.8M New
LXEO Lexeo Therapeutics Inc. 0.23% 175,000 $2.7M New
PRME Prime Medicine Inc. 0.21% 360,000 $2.5M Add +1672.9%
NVAX Novavax Inc. 0.20% 500,000 $2.4M New
PCRX Pacira Biosciences Inc. 0.19% 80,000 $2.3M Reduce -93.3%
ATRA Atara Biotherapeutics Inc. 0.16% 2,800,000 $1.9M New
ACHL Achilles Therapeutics PL-ADR 0.16% 1,500,000 $1.9M Add +1287.8%
CMRX Chimerix Inc. 0.12% 1,400,000 $1.5M No change
RENEO PHARMACEUTICALS INC 0.04% 295,375 $490K Reduce -26.2%
AFMDQ Affimed NV 0.02% 55,000 $292K Add +0.7%
LYEL Lyell Immunopharma Inc. 0.02% 130,000 $290K New

Portfolio Sells Q4 2023 → Q1 2024

INHIBRX INC Sold out 0.00% −6.16
MRK Merck & Co. Inc. Sold out 0.00% −4.62
PCRX Pacira Biosciences Inc. Reduce -93.3% 0.19% −4.10
CBAY Cymabay Therapeutics Inc. Sold out 0.00% −4.07
PCVX Vaxcyte Inc. Sold out 0.00% −3.49
NBIX Neurocrine Biosciences Inc. Reduce -11.3% 8.10% −3.07
VRDN Viridian Therapeutics Inc. Sold out 0.00% −2.31
RVMD Revolution Medicines Inc. Sold out 0.00% −2.20
BIIB Biogen Inc. Sold out 0.00% −2.06
EW Edwards Lifesciences Corp. Sold out 0.00% −1.82
ASND Ascendis Pharma A/S Reduce -16.0% 6.56% −1.78
CRNX Crinetics Pharmaceuticals Inc. Sold out 0.00% −1.70
SNY Sanofi-ADR Sold out 0.00% −1.58
NUVL Nuvalent Inc. Class A Sold out 0.00% −1.56
IMTX Immatics NV Reduce -42.9% 1.04% −1.30
INSM Insmed Inc. Reduce -16.7% 1.68% −1.27
LYRA Lyra Therapeutics Inc. Reduce -73.3% 0.41% −1.25
SLNO Soleno Therapeutics Inc. Reduce -3.9% 4.42% −1.12
AEROVATE THERAPEUTICS INC Sold out 0.00% −0.96
REGN Regeneron Pharmaceuticals Sold out 0.00% −0.93
ARQT Arcutis Biotherapeutics Inc. Sold out 0.00% −0.92
BLUEBIRD BIO INC Sold out 0.00% −0.31
TEVA Teva Pharmaceutical-SP ADR Sold out 0.00% −0.22
FULC Fulcrum Therapeutics Inc. Reduce -32.2% 0.54% −0.19
PYXS Pyxis Oncology Inc. Sold out 0.00% −0.08
IKENA ONCOLOGY INC Sold out 0.00% −0.07
OVID Ovid Therapeutics Inc. Sold out 0.00% −0.03
RENEO PHARMACEUTICALS INC Reduce -26.2% 0.04% −0.03
FATE Fate Therapeutics Inc. Reduce -38.0% 0.49% −0.03

Portfolio Buys Q4 2023 → Q1 2024

CYTK Cytokinetics Inc. Add +4200.0% 12.47% +12.02
ONC Beone Medicines Ltd.-ADR New 4.20% +4.20
ALNY Alnylam Pharmaceuticals Inc. Add +900.0% 4.33% +3.62
NARI Inari Medical Inc. New 3.17% +3.17
ARGX Argenx SE - ADR New 1.63% +1.63
JAZZ Jazz Pharmaceuticals PLC Add +51.7% 10.95% +1.51
APLT Applied Therapeutics Inc. Add +23.0% 2.87% +1.40
TGTX TG Therapeutics Inc. New 1.32% +1.32
ATXS Astria Therapeutics Inc. New 1.28% +1.28
BMRN Biomarin Pharmaceutical Inc. New 1.26% +1.26
ALPN Alpine Immune Sciences Inc. New 1.15% +1.15
LQDA Liquidia Corp. Add +95.1% 2.44% +1.13
SLDB Solid Biosciences Inc. Add +2936.5% 1.14% +1.12
APLS Apellis Pharmaceuticals Inc. New 1.09% +1.09
SRPT Sarepta Therapeutics Inc. New 1.07% +1.07
PRAX Praxis Precision Medicines I New 1.06% +1.06
DNTH Dianthus Therapeutics Inc. Add +237.0% 1.13% +0.98
INCY Incyte Corp. New 0.94% +0.94
MGNX Macrogenics Inc. New 0.88% +0.88
AGIO Agios Pharmaceuticals Inc. New 0.79% +0.79
SWAV Shockwave Medical Inc. New 0.67% +0.67
KRYS Krystal Biotech Inc. New 0.66% +0.66
KALV Kalvista Pharmaceuticals Inc. New 0.64% +0.64
GERN Geron Corp. New 0.60% +0.60
EXAS Exact Sciences Corp. New 0.57% +0.57
XENE Xenon Pharmaceuticals Inc. Add +128.6% 1.42% +0.57
VKTX Viking Therapeutics Inc. New 0.51% +0.51
PASG Passage Bio Inc. New 0.50% +0.50
ALLO Allogene Therapeutics Inc. New 0.50% +0.50
VYGR Voyager Therapeutics Inc. New 0.46% +0.46
AZN Astrazeneca PLC-Spons ADR Add +60.0% 2.24% +0.46
BIO Bio-Rad Laboratories-A New 0.43% +0.43
RARE Ultragenyx Pharmaceutical Inc. New 0.42% +0.42
RLMD Relmada Therapeutics Inc. Add +943.5% 0.46% +0.41
ANRO Alto Neuroscience Inc. New 0.32% +0.32
LXEO Lexeo Therapeutics Inc. New 0.23% +0.23
ACLX Arcellx Inc. Add +66.7% 0.58% +0.22
NVAX Novavax Inc. New 0.20% +0.20
PRME Prime Medicine Inc. Add +1672.9% 0.21% +0.19
ATRA Atara Biotherapeutics Inc. New 0.16% +0.16
ACHL Achilles Therapeutics PL-ADR Add +1287.8% 0.16% +0.14
LYEL Lyell Immunopharma Inc. New 0.02% +0.02
AFMDQ Affimed NV Add +0.7% 0.02% −0.01
GMED Globus Medical Inc. Class A Add +25.0% 4.44% −0.08
ALXO Alx Oncology Holdings Inc. Add +57.7% 2.41% −0.20
QURE Uniqure NV Add +20.4% 2.03% −0.78

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 68$4.3BBMRN, NBIX, ABVX, UTHR, ELVN
Q1 2026 90$3.6BRVMD, BMRN, ABVX, NBIX, ARWR
Q4 2025 75$2.7BABVX, ACLX, TERN, BMRN, GMED
Q3 2025 80$2.2BASND, ACLX, NUVL, ABVX, ALC
Q2 2025 72$1.9BACLX, JAZZ, CYTK, NUVL, VERA
Q1 2025 63$1.4BACLX, CYTK, INSM, NUVL, VERA
Q4 2024 73$1.7BJAZZ, CYTK, MRK, ASND, RARE
Q3 2024 67$1.3BINSM, JAZZ, CYTK, NARI, ACLX
Q2 2024 60$1.3BJAZZ, CYTK, ASND, RARE, GMED
Q1 2024 58$1.2BCYTK, JAZZ, NBIX, ASND, GMED