Pyxis OncologyPYXS
13F holders, Q2 2026 (June 30)76holders −2
9new positions
10sold out
4famous investors
$2.96avg. 13F price*
At the end of Q2 2026, 76 institutions reported holding Pyxis Oncology Inc. (PYXS) in their 13F filings, down 2 from Q1 2026. 9 opened new positions and 10 sold out. The largest holders were GordonMD Global Investments LP ($30.2M), Pfizer Inc ($19.5M) and Laurion Capital Management LP ($14.8M). 4 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Steve Cohen (0.0% of Point72 Asset Management's portfolio).
- Company
- Pyxis Oncology Inc.
- CUSIP
- 747324101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2026 → Q2 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 9 | $2.3M |
| Exits | 10 | $351K |
All 13F filers, Q1 2026 → Q2 2026: 8,293,294 shares bought and 1,711,011 shares sold, net +6,582,283 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 76 holders
| GordonMD Global Investments LP | 14.60% | Add +143.2% | 10,024,909 | $30.2M |
| Pfizer Inc | 11.43% | No change | 7,032,770 | $19.5M |
| Laurion Capital Management LP | 1.11% | Reduce -1.9% | 4,900,888 | $14.8M |
| Vanguard Capital Management LLC | 0.00% | Add +2.1% | 2,075,997 | $6.2M |
| Atle Fund Management AB | 0.78% | Add +390.5% | 966,459 | $2.9M |
| BlackRock, Inc. | 0.00% | Add +10.0% | 867,934 | $2.6M |
| Palo Alto Investors LP | 0.36% | Reduce -14.5% | 864,277 | $2.6M |
| Marshall Wace, LLP | 0.00% | Add +134.3% | 830,544 | $2.5M |
| Renaissance Technologies | 0.00% | Reduce -13.1% | 772,232 | $2.3M |
| Geode Capital Management, LLC | 0.00% | Reduce -1.1% | 591,849 | $1.8M |
| Woodline Partners LP | 0.00% | New | 523,999 | $1.6M |
| 683 Capital Management, LLC | 0.13% | Reduce -48.8% | 459,367 | $1.4M |
| Jacobs Levy Equity Management, Inc. | 0.00% | Reduce -7.0% | 428,606 | $1.3M |
| Longaeva Partners L.P. | 0.03% | Reduce -29.7% | 353,582 | $1.1M |
| Decheng Capital LLC | 0.13% | No change | 326,810 | $984K |
| Vanguard Fiduciary Trust Co. | 0.00% | Add +0.7% | 302,986 | $912K |
| Jane Street Group, LLC | 0.00% | Reduce -4.7% | 290,090 | $873K |
| State Street Corp. | 0.00% | No change | 248,837 | $749K |
| Millennium Management | 0.00% | Reduce -41.4% | 233,004 | $701K |
| UBS Group AG | 0.00% | Reduce -38.9% | 155,217 | $467K |
| Bank of New York Mellon Corp | 0.00% | No change | 133,996 | $403K |
| Acadian Asset Management LLC | 0.00% | Reduce -12.1% | 126,793 | $380K |
| Northern Trust Corp. | 0.00% | Add +21.6% | 123,959 | $373K |
| NewEdge Wealth, LLC | 0.00% | No change | 116,006 | $349K |
| XTX Topco Ltd | 0.00% | Reduce -44.6% | 110,939 | $334K |
| Two Sigma Investments, LP | 0.00% | Add +14.5% | 83,961 | $253K |
| Bridgeway Capital Management, LLC | 0.00% | No change | 81,260 | $245K |
| Bank of America Corp. | 0.00% | Add +378.8% | 80,464 | $242K |
| Stifel Financial Corp. | 0.00% | Add +39.4% | 70,437 | $212K |
| Cable Car Capital, LP | 0.00% | No change | 61,606 | $185K |
| MYDA Advisors LLC | 0.04% | New | 50,000 | $151K |
| Qube Research & Technologies Ltd | 0.00% | Add +342.4% | 49,932 | $150K |
| University of Chicago | 0.03% | No change | 48,731 | $147K |
| Citadel Advisors | 0.00% | Reduce -22.8% | 47,317 | $142K |
| Quadrature Capital Ltd | 0.00% | New | 47,067 | $142K |
| Goldman Sachs Group Inc. | 0.00% | Reduce -2.2% | 45,900 | $138K |
| Verdad Advisers, LP | 0.13% | New | 44,899 | $135K |
| LPL Financial LLC | 0.00% | Add +29.8% | 43,554 | $131K |
| Commonwealth Equity Services, LLC | 0.00% | Add +22.2% | 42,455 | $128K |
| J. Derek Lewis & Associates Inc. | 0.02% | Reduce -2.3% | 42,000 | $126K |
| Citigroup Inc. | 0.00% | Add +2095.7% | 38,205 | $115K |
| Simplex Trading, LLC | 0.00% | Add +14881.0% | 37,902 | $114K |
| Point72 Asset Management | 0.00% | Add +15.9% | 37,092 | $112K |
| Walleye Capital LLC | 0.00% | New | 36,778 | $111K |
| Dimensional Fund Advisors LP | 0.00% | Add +39.6% | 36,175 | $109K |
| Morgan Stanley | 0.00% | Reduce -52.0% | 33,448 | $101K |
| Mackenzie Financial Corp. | 0.00% | New | 26,343 | $79K |
| Cetera Investment Advisers | 0.00% | Reduce -8.3% | 25,000 | $75K |
| Graham Capital Management, L.P. | 0.00% | Reduce -0.2% | 22,708 | $68K |
| Vanguard Global Advisers, LLC | 0.00% | No change | 21,242 | $64K |
| Osaic Holdings, Inc. | 0.00% | Add +29.1% | 17,721 | $53K |
| Group One Trading LLC | 0.00% | New | 16,480 | $50K |
| FMR LLC | 0.00% | Add +4.0% | 12,383 | $37K |
| Paces Ferry Wealth Advisors, LLC | 0.01% | No change | 11,440 | $34K |
| NewEdge Advisors, LLC | 0.00% | No change | 10,250 | $31K |
| China Universal Asset Management Co., Ltd. | 0.00% | Reduce -8.7% | 10,083 | $30K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -9.0% | 9,398 | $28K |
| PNC Financial Services Group, Inc. | 0.00% | No change | 6,500 | $20K |
| Winthrop Capital Management, LLC | 0.00% | No change | 6,000 | $18K |
| JPMorgan Chase & Co. | 0.00% | Add +7.2% | 5,545 | $16K |
| Hager Investment Management Services, LLC | 0.01% | No change | 5,000 | $15K |
| Barclays PLC | 0.00% | Reduce -90.6% | 4,669 | $14K |
| Federation des caisses Desjardins du Quebec | 0.00% | New | 4,500 | $14K |
| Federated Hermes, Inc. | 0.00% | Reduce -6.9% | 2,962 | $9K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Reduce -12.8% | 2,833 | $9K |
| BNP Paribas Financial Markets | 0.00% | Add +62.6% | 2,689 | $8K |
| First United Bank & Trust | 0.00% | New | 2,500 | $7K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -6.8% | 1,226 | $4K |
| Nisa Investment Advisors, LLC | 0.00% | No change | 961 | $3K |
| Physician Wealth Advisors, Inc. | 0.00% | No change | 943 | $3K |
| SBI Securities Co., Ltd. | 0.00% | Add +50800.0% | 509 | $2K |
| Jones Financial Companies LLLP | 0.00% | No change | 500 | $1K |
| Wells Fargo & Company | 0.00% | No change | 285 | $858 |
| Cornerstone Financial Management LLC | 0.00% | No change | 172 | $518 |
| Caitong International Asset Management Co., Ltd | 0.00% | Add +775.0% | 35 | $105 |
| Arax Advisory Partners | 0.00% | Add +1300.0% | 14 | $42 |
"% of holder's portfolio" is PYXS's weight in each manager's 13F, not the share of Pyxis Oncology Inc. the manager owns.