Agios PharmaceuticalsAGIO
13F holders, Q1 2025 (March 31)At the end of Q1 2025, 221 institutions reported holding Agios Pharmaceuticals Inc. (AGIO) in their 13F filings, down 4 from Q4 2024. 33 opened new positions and 39 sold out. The largest holders were Farallon Capital Management, L.L.C. ($167.0M), Vanguard Group Inc. ($164.2M) and BlackRock, Inc. ($149.7M). 5 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Ken Fisher (0.0% of Fisher Asset Management's portfolio).
- Company
- Agios Pharmaceuticals Inc.
- CUSIP
- 00847X104
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 33 | $102.4M |
| Exits | 39 | $146.3M |
All 13F filers, Q4 2024 → Q1 2025: 7,568,922 shares bought and 7,285,036 shares sold, net +283,886 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 221 holders
| Farallon Capital Management, L.L.C. | 0.90% | Add +0.5% | 5,700,466 | $167.0M |
| Vanguard Group Inc. | 0.00% | Reduce -0.5% | 5,604,591 | $164.2M |
| BlackRock, Inc. | 0.00% | Add +1.8% | 5,108,746 | $149.7M |
| Bellevue Group AG | 2.31% | No change | 3,515,150 | $103.0M |
| State Street Corp. | 0.00% | Add +13.8% | 2,449,479 | $71.8M |
| T. Rowe Price Associates Inc. | 0.01% | Reduce -5.0% | 2,301,353 | $67.4M |
| Erste Asset Management GmbH | 0.84% | Add +10.9% | 2,229,900 | $65.4M |
| Commodore Capital LP | 4.72% | New | 2,185,000 | $64.0M |
| Armistice Capital, LLC | 1.60% | Reduce -9.6% | 2,048,000 | $60.0M |
| Macquarie Group Ltd. | 0.07% | Add +9.8% | 1,850,544 | $54.2M |
| Geode Capital Management, LLC | 0.00% | Add +3.3% | 1,394,581 | $40.9M |
| Dimensional Fund Advisors LP | 0.01% | Reduce -5.0% | 1,262,073 | $37.0M |
| Bank of America Corp. | 0.00% | Add +180.5% | 1,135,592 | $33.3M |
| Frazier Life Sciences Management, L.P. | 1.44% | Add +0.0% | 1,069,854 | $31.3M |
| JPMorgan Chase & Co. | 0.00% | Add +3.4% | 1,049,360 | $30.7M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.08% | Add +8.9% | 1,025,719 | $30.1M |
| Polar Capital Holdings Plc | 0.18% | Add +59.8% | 1,002,036 | $29.4M |
| Fisher Asset Management | 0.01% | Reduce -0.1% | 959,339 | $28.1M |
| Deutsche Bank AG | 0.01% | Reduce -0.7% | 928,970 | $27.2M |
| Citadel Advisors | 0.03% | Reduce -39.8% | 863,499 | $25.3M |
| ArrowMark Colorado Holdings LLC | 0.39% | Reduce -9.8% | 827,623 | $24.2M |
| GW&K Investment Management, LLC | 0.22% | Add +19.6% | 817,526 | $24.0M |
| Adage Capital Partners Gp, L.L.C. | 0.04% | Add +145.2% | 743,000 | $21.8M |
| Caligan Partners LP | 4.29% | Add +12.0% | 701,280 | $20.5M |
| Goldman Sachs Group Inc. | 0.00% | Add +16.1% | 658,652 | $19.3M |
| SCS Capital Management LLC | 0.23% | New | 611,098 | $17.9M |
| Northern Trust Corp. | 0.00% | Reduce -3.2% | 576,258 | $16.9M |
| D. E. Shaw & Co. | 0.02% | Add +7.4% | 554,820 | $16.3M |
| Marshall Wace, LLP | 0.02% | Reduce -17.5% | 520,873 | $15.3M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -1.6% | 464,958 | $13.6M |
| Artisan Partners Limited Partnership | 0.02% | Reduce -17.7% | 410,672 | $12.0M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.05% | Add +207.6% | 386,523 | $11.3M |
| Rock Springs Capital Management LP | 0.58% | Reduce -27.4% | 342,180 | $10.0M |
| Voloridge Investment Management, LLC | 0.04% | Add +65.4% | 331,643 | $9.7M |
| Eagle Health Investments LP | 2.52% | No change | 330,830 | $9.7M |
| Orbimed Advisors LLC | 0.23% | Add +1119.1% | 325,500 | $9.5M |
| Pictet Asset Management Holding SA | 0.01% | Reduce -12.3% | 310,781 | $9.4M |
| Morgan Stanley | 0.00% | Reduce -22.1% | 294,623 | $8.6M |
| Palo Alto Investors LP | 1.54% | New | 276,578 | $8.1M |
| Bank of New York Mellon Corp | 0.00% | Reduce -0.8% | 263,450 | $7.7M |
| Boothbay Fund Management, LLC | 0.28% | Add +3.8% | 261,221 | $7.7M |
| Casdin Capital, LLC | 0.60% | No change | 250,000 | $7.3M |
| Cutter Capital Management, LP | 3.00% | Reduce -22.0% | 235,350 | $6.9M |
| AXA S.A. | 0.02% | Add +28.4% | 225,119 | $6.6M |
| Nordea Investment Management AB | 0.01% | Add +1.6% | 224,173 | $6.5M |
| Prudential Financial Inc. | 0.01% | Add +94.7% | 204,242 | $6.0M |
| TD Asset Management Inc | 0.00% | Add +7.5% | 178,072 | $5.2M |
| Citigroup Inc. | 0.00% | Reduce -8.8% | 176,128 | $5.2M |
| Nuveen, LLC | 0.00% | — | 83,409 | $4.4M |
| Walleye Capital LLC | 0.05% | Reduce -24.6% | 150,511 | $4.4M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +19.9% | 147,276 | $4.3M |
| Patient Square Capital LP | 1.69% | Add +14.8% | 139,732 | $4.1M |
| Granahan Investment Management, LLC | 0.19% | Add +14.2% | 132,108 | $3.9M |
| UBS Group AG | 0.00% | Reduce -43.8% | 131,642 | $3.9M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +7.8% | 131,571 | $3.9M |
| Qube Research & Technologies Ltd | 0.01% | Reduce -36.0% | 127,980 | $3.7M |
| Jane Street Group, LLC | 0.01% | Reduce -41.1% | 126,104 | $3.7M |
| American Century Companies Inc. | 0.00% | Add +9.6% | 114,947 | $3.4M |
| Barclays PLC | 0.00% | Reduce -7.1% | 113,153 | $3.3M |
| Hudson Bay Capital Management LP | 0.02% | Add +0.7% | 110,720 | $3.2M |
| CenterBook Partners LP | 0.20% | Reduce -64.5% | 108,509 | $3.2M |
| Invesco Ltd. | 0.00% | Add +28.6% | 107,367 | $3.1M |
| Swiss National Bank | 0.00% | Reduce -1.3% | 99,460 | $2.9M |
| Rafferty Asset Management, LLC | 0.01% | Add +33.2% | 93,627 | $2.7M |
| Allianz Asset Management GmbH | 0.00% | Reduce -22.2% | 92,233 | $2.7M |
| Rhumbline Advisers | 0.00% | Reduce -8.1% | 86,842 | $2.5M |
| Silvercrest Asset Management Group LLC | 0.02% | Reduce -0.6% | 82,679 | $2.4M |
| Susquehanna International Group, LLP | 0.00% | Reduce -51.9% | 81,962 | $2.4M |
| Norges Bank | 0.00% | Reduce -46.6% | 77,544 | $2.3M |
| Algert Global LLC | 0.05% | Add +511.2% | 74,810 | $2.2M |
| Capital Fund Management S.A. | 0.03% | New | 72,302 | $2.1M |
| Caption Management, LLC | 0.09% | Reduce -33.0% | 70,000 | $2.1M |
| State of Wisconsin Investment Board | 0.01% | Add +2.0% | 69,684 | $2.0M |
| Wells Fargo & Company | 0.00% | Add +95.8% | 68,137 | $2.0M |
| Franklin Resources Inc. | 0.00% | Add +2.4% | 68,072 | $2.0M |
| Kennedy Capital Management LLC | 0.04% | Reduce -43.3% | 62,953 | $1.8M |
| Alliancebernstein L.P. | 0.00% | Reduce -0.0% | 61,478 | $1.8M |
| Legal & General Group Plc | 0.00% | Reduce -16.2% | 60,043 | $1.8M |
| Moore Capital Management, LP | 0.07% | No change | 60,000 | $1.8M |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0.04% | Add +35.5% | 58,722 | $1.7M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | New | 54,651 | $1.6M |
| Millennium Management | 0.00% | Add +139.1% | 53,073 | $1.6M |
| AQR Capital Management | 0.00% | Add +66.8% | 51,489 | $1.5M |
| Kodai Capital Management LP | 0.06% | New | 50,692 | $1.5M |
| Panagora Asset Management Inc. | 0.01% | No change | 47,221 | $1.4M |
| California State Teachers Retirement System | 0.00% | Reduce -2.6% | 46,988 | $1.4M |
| Ameriprise Financial Inc. | 0.00% | Add +19.2% | 46,811 | $1.4M |
| HighVista Strategies LLC | 0.50% | New | 44,105 | $1.3M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +7.2% | 43,327 | $1.3M |
| Alps Advisors Inc. | 0.01% | Reduce -8.4% | 42,219 | $1.2M |
| Gsa Capital Partners LLP | 0.11% | Reduce -22.9% | 41,029 | $1.2M |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 40,000 | $1.2M |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 0.01% | — | 39,261 | $1.2M |
| New York State Common Retirement Fund | 0.00% | No change | 39,093 | $1.1M |
| Oak Ridge Investments LLC | 0.10% | Add +0.6% | 39,087 | $1.1M |
| Squarepoint Ops LLC | 0.00% | Reduce -76.7% | 37,920 | $1.1M |
| First Trust Advisors LP | 0.00% | Reduce -61.6% | 37,330 | $1.1M |
| Harbor Capital Advisors, Inc. | 0.05% | Add +5.8% | 35,729 | $1.0M |
| Intech Investment Management LLC | 0.01% | Add +24.9% | 35,289 | $1.0M |
| Edgewood Management LLC | 0.00% | Add +16.7% | 35,000 | $1.0M |
| MetLife Investment Management, LLC | 0.01% | Reduce -1.6% | 34,032 | $997K |
| Royal Bank of Canada | 0.00% | Reduce -3.2% | 33,237 | $973K |
| Cantor Fitzgerald, L. P. | 0.04% | New | 32,000 | $938K |
| Ensign Peak Advisors, Inc | 0.00% | No change | 31,920 | $935K |
| Capula Management Ltd | 0.01% | Add +42.7% | 29,749 | $872K |
| ADAR1 Capital Management, LLC | 0.16% | New | 27,900 | $817K |
| Verition Fund Management LLC | 0.00% | Reduce -40.7% | 27,753 | $813K |
| Corebridge Financial, Inc. | 0.00% | Reduce -1.5% | 27,688 | $811K |
| Janus Henderson Group PLC | 0.00% | No change | 23,797 | $721K |
| Wellington Management Group LLP | 0.00% | Reduce -4.0% | 24,462 | $717K |
| Schonfeld Strategic Advisors LLC | 0.00% | Reduce -24.2% | 23,600 | $691K |
| Engineers Gate Manager LP | 0.01% | Reduce -62.3% | 22,717 | $666K |
| Envestnet Asset Management Inc. | 0.00% | Reduce -9.1% | 22,553 | $661K |
| Allen Investment Management, LLC | 0.01% | No change | 21,781 | $638K |
| BIT Capital GmbH | 0.08% | New | 21,468 | $629K |
| Woodline Partners LP | 0.00% | New | 20,381 | $597K |
| Profund Advisors LLC | 0.02% | Add +38.1% | 19,582 | $574K |
| CANADA LIFE ASSURANCE Co | 0.00% | Add +2.3% | 19,408 | $570K |
| Handelsbanken Fonder AB | 0.00% | No change | 19,323 | $566K |
| Tidal Investments LLC | 0.00% | Reduce -7.6% | 19,218 | $563K |
| Guggenheim Capital LLC | 0.01% | Add +36.9% | 18,755 | $550K |
| FMR LLC | 0.00% | Reduce -29.7% | 17,806 | $522K |
| Thrivent Financial for Lutherans | 0.00% | No change | 17,526 | $514K |
| Federated Hermes, Inc. | 0.00% | Add +16.0% | 15,885 | $465K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 15,847 | $464K |
| Voya Investment Management LLC | 0.00% | Reduce -53.8% | 15,247 | $447K |
| Centiva Capital, LP | 0.03% | New | 15,032 | $440K |
| ProShare Advisors LLC | 0.00% | Reduce -20.4% | 14,821 | $434K |
| Arizona State Retirement System | 0.00% | Reduce -0.9% | 14,698 | $431K |
| Atria Investments, Inc | 0.01% | Add +28.4% | 14,595 | $428K |
| Henshaw Capital LLC | 0.02% | No change | 14,041 | $411K |
| Teacher Retirement System of Texas | 0.00% | Reduce -9.0% | 13,813 | $405K |
| XTX Topco Ltd | 0.02% | Add +48.9% | 13,801 | $404K |
| Sei Investments Co. | 0.00% | Add +1.1% | 13,747 | $403K |
| Group One Trading LLC | 0.02% | Reduce -28.4% | 13,188 | $386K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | No change | 12,836 | $376K |
| Gallagher Fiduciary Advisors, LLC | 0.01% | Add +15.5% | 12,830 | $376K |
| Cibc World Markets Corp. | 0.00% | New | 12,541 | $367K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 12,032 | $353K |
| Creative Planning | 0.00% | Reduce -9.2% | 11,922 | $349K |
| Inspire Investing, LLC | 0.04% | Reduce -5.0% | 11,768 | $345K |
| Man Group plc | 0.00% | New | 11,622 | $341K |
| China Universal Asset Management Co., Ltd. | 0.03% | Reduce -5.0% | 11,493 | $337K |
| Catalyst Funds Management Pty Ltd | 0.09% | New | 11,200 | $328K |
| SummitTX Capital, L.P. | 0.01% | — | 10,768 | $316K |
| Headlands Technologies LLC | 0.04% | Reduce -59.9% | 10,715 | $314K |
| ExodusPoint Capital Management, LP | 0.00% | New | 10,553 | $309K |
| KLP Kapitalforvaltning As | 0.00% | No change | 10,000 | $293K |
| Virtus Investment Advisers, LLC | 0.08% | New | 9,408 | $276K |
| Victory Capital Management Inc. | 0.00% | Add +28.8% | 8,784 | $257K |
| E Fund Management Co., Ltd. | 0.01% | New | 8,750 | $256K |
| Russell Investments Group, Ltd. | 0.00% | Add +207.6% | 8,558 | $251K |
| STRS Ohio | 0.00% | Reduce -64.2% | 8,200 | $240K |
| Commerce Bank | 0.00% | New | 8,199 | $240K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 6,796 | $199K |
| Ameritas Investment Partners, Inc. | 0.01% | No change | 5,913 | $173K |
| Acadian Asset Management LLC | 0.00% | New | 4,544 | $133K |
| BNP Paribas Financial Markets | 0.00% | Reduce -55.3% | 4,336 | $127K |
| PNC Financial Services Group, Inc. | 0.00% | Add +16.2% | 3,582 | $105K |
| KBC Group NV | 0.00% | No change | 2,615 | $77K |
| Lazard Asset Management LLC | 0.00% | New | 2,658 | $77K |
| Wilmington Savings Fund Society, FSB | 0.00% | New | 2,111 | $62K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +0.9% | 1,917 | $58K |
| Amalgamated Bank | 0.00% | Add +0.4% | 1,957 | $57K |
| Cwm, LLC | 0.00% | Add +150.2% | 1,659 | $49K |
| GF Fund Management Co. LTD. | 0.00% | Add +22.0% | 1,460 | $43K |
| Coldstream Capital Management Inc. | 0.00% | New | 1,365 | $40K |
| NewEdge Advisors, LLC | 0.00% | New | 1,355 | $40K |
| State of Wyoming | 0.01% | Add +8.9% | 1,314 | $39K |
| Sterling Capital Management LLC | 0.00% | Reduce -45.3% | 975 | $29K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -91.5% | 877 | $25K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -1.7% | 822 | $24K |
| Assetmark, Inc. | 0.00% | Add +45.0% | 805 | $24K |
| US Bancorp \de | 0.00% | Add +15.7% | 559 | $16K |
| First Horizon Advisors, Inc. | 0.00% | Add +7.9% | 544 | $16K |
| Parallel Advisors, LLC | 0.00% | Add +2.4% | 504 | $15K |
| Signaturefd, LLC | 0.00% | Reduce -6.7% | 477 | $14K |
| AlphaQuest LLC | 0.00% | Reduce -91.8% | 373 | $11K |
| Hurley Capital, LLC | 0.01% | New | 366 | $11K |
| Aspect Partners, LLC | 0.01% | No change | 361 | $11K |
| Lanark Financial, Inc. | 0.00% | — | 345 | $10K |
| Smartleaf Asset Management LLC | 0.00% | Add +19.4% | 314 | $10K |
| GAMMA Investing LLC | 0.00% | Add +220.7% | 279 | $8K |
| Lindbrook Capital, LLC | 0.00% | Add +57.7% | 257 | $8K |
| Bell Investment Advisors, Inc | 0.00% | No change | 237 | $7K |
| Spire Wealth Management | 0.00% | No change | 230 | $7K |
| Optiver Holding B.V. | 0.00% | New | 215 | $6K |
| Daiwa Securities Group Inc. | 0.00% | No change | 204 | $6K |
| Concord Wealth Partners | 0.00% | No change | 200 | $6K |
| Hillsdale Investment Management Inc. | 0.00% | No change | 200 | $6K |
| Comerica Bank | 0.00% | Add +5.6% | 190 | $6K |
| Kestra Investment Management, LLC | 0.00% | New | 139 | $4K |
| Rothschild Investment LLC | 0.00% | Add +340.0% | 110 | $3K |
| Bessemer Group Inc. | 0.00% | Reduce -8.3% | 110 | $3K |
| Private Wealth Management Group, LLC | 0.00% | No change | 84 | $2K |
| Mather Group, Llc. | 0.00% | New | 80 | $2K |
| Quadrant Capital Group LLC | 0.00% | Reduce -27.0% | 73 | $2K |
| Caitong International Asset Management Co., Ltd | 0.00% | Reduce -94.1% | 45 | $1K |
| Riggs Asset Managment Co. Inc. | 0.00% | No change | 41 | $1K |
| EverSource Wealth Advisors, LLC | 0.00% | Reduce -12.8% | 41 | $1K |
| MAI Capital Management | 0.00% | Add +90.0% | 38 | $1K |
| Osaic Holdings, Inc. | 0.00% | Reduce -87.5% | 35 | $1K |
| Raffa Wealth Management, LLC | 0.00% | No change | 32 | $938 |
| Parkside Financial Bank & Trust | 0.00% | New | 30 | $879 |
| Principal Securities, Inc. | 0.00% | No change | 25 | $822 |
| Arax Advisory Partners | 0.00% | Reduce -75.6% | 20 | $586 |
| Stephens Consulting, LLC | 0.00% | New | 15 | $440 |
| Farther Finance Advisors, LLC | 0.00% | Reduce -33.3% | 12 | $329 |
| Allworth Financial LP | 0.00% | Reduce -82.8% | 11 | $322 |
| Steward Partners Investment Advisory, LLC | 0.00% | No change | 9 | $264 |
| True Wealth Design, LLC | 0.00% | New | 5 | $147 |
| JFS Wealth Advisors, LLC | 0.00% | Reduce -66.7% | 5 | $147 |
| SouthState Bank Corp | 0.00% | New | 4 | $117 |
| SBI Securities Co., Ltd. | 0.00% | No change | 3 | $88 |
| Global Financial Private Client, LLC | 0.00% | Add +50.0% | 3 | $88 |
| SJS Investment Consulting Inc. | 0.00% | Reduce -77.8% | 2 | $59 |
| DiNuzzo Private Wealth, Inc. | 0.00% | Reduce -66.7% | 2 | $59 |
| HFM Investment Advisors, LLC | 0.00% | — | 1 | $30 |
| Bay Harbor Wealth Management, LLC | 0.00% | New | 1 | $29 |
| Hemington Wealth Management | 0.00% | Reduce -19.2% | 21 | $0 |
| Covestor Ltd | 0.00% | Reduce -40.0% | 3 | $0 |
"% of holder's portfolio" is AGIO's weight in each manager's 13F, not the share of Agios Pharmaceuticals Inc. the manager owns.