Agios PharmaceuticalsAGIO
13F holders, Q2 2025 (June 30)At the end of Q2 2025, 215 institutions reported holding Agios Pharmaceuticals Inc. (AGIO) in their 13F filings, down 6 from Q1 2025. 21 opened new positions and 24 sold out. The largest holders were Farallon Capital Management, L.L.C. ($191.8M), Vanguard Group Inc. ($189.0M) and BlackRock, Inc. ($160.8M). 5 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Ken Fisher (0.0% of Fisher Asset Management's portfolio).
- Company
- Agios Pharmaceuticals Inc.
- CUSIP
- 00847X104
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 21 | $75.2M |
| Exits | 24 | $41.8M |
All 13F filers, Q1 2025 → Q2 2025: 6,663,002 shares bought and 4,786,613 shares sold, net +1,876,389 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 215 holders
| Farallon Capital Management, L.L.C. | 0.88% | Add +1.2% | 5,767,466 | $191.8M |
| Vanguard Group Inc. | 0.00% | Add +1.4% | 5,682,019 | $189.0M |
| BlackRock, Inc. | 0.00% | Reduce -5.4% | 4,833,760 | $160.8M |
| Bellevue Group AG | 2.63% | Add +2.1% | 3,590,150 | $119.4M |
| Erste Asset Management GmbH | 0.65% | Add +4.3% | 2,326,489 | $77.4M |
| Commodore Capital LP | 5.46% | Add +6.4% | 2,325,000 | $77.3M |
| T. Rowe Price Associates Inc. | 0.01% | Reduce -1.2% | 2,274,249 | $75.6M |
| State Street Corp. | 0.00% | Reduce -20.4% | 1,951,113 | $64.9M |
| Macquarie Group Ltd. | 0.08% | Add +2.7% | 1,900,596 | $63.2M |
| Geode Capital Management, LLC | 0.00% | Add +0.8% | 1,405,755 | $46.8M |
| Frazier Life Sciences Management, L.P. | 1.70% | Add +19.6% | 1,279,754 | $42.6M |
| Armistice Capital, LLC | 1.47% | Reduce -43.0% | 1,168,000 | $38.8M |
| Paradigm Biocapital Advisors LP | 1.62% | New | 1,142,511 | $38.0M |
| Bank of America Corp. | 0.00% | Reduce -1.4% | 1,120,308 | $37.3M |
| Dimensional Fund Advisors LP | 0.01% | Reduce -12.4% | 1,106,093 | $36.8M |
| Citadel Advisors | 0.03% | Add +25.2% | 1,081,470 | $36.0M |
| Caligan Partners LP | 6.92% | Add +52.8% | 1,071,258 | $35.6M |
| JPMorgan Chase & Co. | 0.00% | Reduce -2.1% | 1,027,417 | $34.2M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.08% | Reduce -0.9% | 1,016,891 | $33.8M |
| Rock Springs Capital Management LP | 2.06% | Add +189.3% | 989,745 | $32.9M |
| Deutsche Bank AG | 0.01% | Reduce -0.8% | 921,586 | $30.7M |
| Fisher Asset Management | 0.01% | Reduce -8.5% | 877,540 | $29.2M |
| GW&K Investment Management, LLC | 0.26% | Add +6.3% | 868,618 | $28.9M |
| Adage Capital Partners Gp, L.L.C. | 0.04% | Add +6.5% | 791,000 | $26.3M |
| TCG Crossover Management, LLC | 2.65% | New | 697,003 | $23.2M |
| Marshall Wace, LLP | 0.03% | Add +31.4% | 684,669 | $22.8M |
| ArrowMark Colorado Holdings LLC | 0.39% | Reduce -20.4% | 658,691 | $21.9M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -1.6% | 648,061 | $21.6M |
| SCS Capital Management LLC | 0.22% | Reduce -1.1% | 604,085 | $20.1M |
| D. E. Shaw & Co. | 0.02% | Add +7.5% | 596,202 | $19.8M |
| Orbimed Advisors LLC | 0.47% | Add +71.4% | 557,900 | $18.6M |
| Northern Trust Corp. | 0.00% | Reduce -3.4% | 556,805 | $18.5M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.06% | Add +30.7% | 505,225 | $16.8M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +2.4% | 476,041 | $15.8M |
| Boothbay Fund Management, LLC | 0.47% | Add +71.1% | 447,019 | $14.9M |
| Wellington Management Group LLP | 0.00% | Add +1625.7% | 422,129 | $14.0M |
| Artisan Partners Limited Partnership | 0.02% | Reduce -5.0% | 389,984 | $13.0M |
| Eagle Health Investments LP | 2.72% | No change | 330,830 | $11.0M |
| Millennium Management | 0.01% | Add +465.6% | 300,203 | $10.0M |
| Pictet Asset Management Holding SA | 0.01% | Reduce -5.2% | 294,740 | $9.9M |
| Morgan Stanley | 0.00% | Reduce -0.9% | 291,965 | $9.7M |
| Palo Alto Investors LP | 1.90% | Reduce -2.8% | 268,783 | $8.9M |
| Bank of New York Mellon Corp | 0.00% | Add +1.2% | 266,654 | $8.9M |
| CenterBook Partners LP | 0.45% | Add +124.0% | 243,063 | $8.1M |
| Woodline Partners LP | 0.04% | Add +1043.6% | 233,068 | $7.8M |
| Nordea Investment Management AB | 0.01% | Add +0.3% | 224,746 | $7.5M |
| AXA S.A. | 0.02% | Add +0.1% | 225,367 | $7.5M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +47.6% | 217,402 | $7.2M |
| Baker Bros. Advisors LP | 0.06% | New | 189,866 | $6.3M |
| Voloridge Investment Management, LLC | 0.02% | Reduce -43.5% | 187,395 | $6.2M |
| Barclays PLC | 0.00% | Add +59.7% | 180,704 | $6.0M |
| TD Asset Management Inc | 0.00% | Reduce -5.5% | 168,194 | $5.6M |
| Prudential Financial Inc. | 0.01% | Reduce -22.5% | 158,359 | $5.3M |
| Patient Square Capital LP | 1.68% | No change | 139,732 | $4.6M |
| Allianz Asset Management GmbH | 0.01% | Add +50.6% | 138,898 | $4.6M |
| Cantor Fitzgerald, L. P. | 0.11% | Add +319.4% | 134,200 | $4.5M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +0.4% | 132,083 | $4.4M |
| Hudson Bay Capital Management LP | 0.03% | Add +17.4% | 130,000 | $4.3M |
| American Century Companies Inc. | 0.00% | Add +11.1% | 127,647 | $4.2M |
| Nuveen, LLC | 0.00% | Add +43.4% | 119,580 | $4.0M |
| UBS Group AG | 0.00% | Reduce -9.7% | 118,834 | $4.0M |
| Invesco Ltd. | 0.00% | Add +4.9% | 112,617 | $3.7M |
| Swiss National Bank | 0.00% | Add +10.1% | 109,460 | $3.6M |
| Casdin Capital, LLC | 0.30% | Reduce -60.0% | 100,000 | $3.3M |
| Trexquant Investment LP | 0.04% | New | 98,401 | $3.3M |
| AQR Capital Management | 0.00% | Add +88.2% | 96,896 | $3.2M |
| Rhumbline Advisers | 0.00% | Add +3.5% | 89,881 | $3.0M |
| Algert Global LLC | 0.06% | Add +18.7% | 88,830 | $3.0M |
| Silvercrest Asset Management Group LLC | 0.02% | No change | 82,679 | $2.7M |
| Moore Capital Management, LP | 0.06% | Add +33.3% | 80,000 | $2.7M |
| HighVista Strategies LLC | 0.86% | Add +59.0% | 70,127 | $2.3M |
| Capital Fund Management S.A. | 0.03% | Reduce -5.3% | 68,502 | $2.3M |
| Susquehanna International Group, LLP | 0.00% | Reduce -16.9% | 68,103 | $2.3M |
| Qube Research & Technologies Ltd | 0.00% | Reduce -47.4% | 67,379 | $2.2M |
| Legal & General Group Plc | 0.00% | Add +7.1% | 64,305 | $2.1M |
| Alliancebernstein L.P. | 0.00% | Reduce -0.0% | 61,470 | $2.0M |
| State of Wisconsin Investment Board | 0.00% | Reduce -15.2% | 59,100 | $2.0M |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0.05% | Reduce -3.3% | 56,810 | $1.9M |
| Citigroup Inc. | 0.00% | Reduce -67.9% | 56,489 | $1.9M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | Add +1.2% | 55,284 | $1.8M |
| Ameriprise Financial Inc. | 0.00% | Add +11.6% | 52,252 | $1.7M |
| Franklin Resources Inc. | 0.00% | Reduce -26.4% | 50,108 | $1.7M |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 0.01% | Add +26.5% | 49,661 | $1.7M |
| Rafferty Asset Management, LLC | 0.01% | Reduce -47.2% | 49,403 | $1.6M |
| California State Teachers Retirement System | 0.00% | Add +1.4% | 47,659 | $1.6M |
| Panagora Asset Management Inc. | 0.01% | Reduce -0.1% | 47,190 | $1.6M |
| Schonfeld Strategic Advisors LLC | 0.01% | Add +96.4% | 46,346 | $1.5M |
| Granahan Investment Management, LLC | 0.06% | Reduce -68.3% | 41,886 | $1.4M |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 40,000 | $1.3M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -8.7% | 39,579 | $1.3M |
| New York State Common Retirement Fund | 0.00% | No change | 39,093 | $1.3M |
| Wells Fargo & Company | 0.00% | Reduce -44.7% | 37,694 | $1.3M |
| Oak Ridge Investments LLC | 0.09% | Reduce -4.7% | 37,252 | $1.2M |
| Harbor Capital Advisors, Inc. | 0.05% | Add +3.6% | 37,024 | $1.2M |
| Kennedy Capital Management LLC | 0.03% | Reduce -41.7% | 36,705 | $1.2M |
| First Trust Advisors LP | 0.00% | Reduce -2.4% | 36,427 | $1.2M |
| ADAR1 Capital Management, LLC | 0.20% | Add +28.7% | 35,900 | $1.2M |
| Edgewood Management LLC | 0.00% | No change | 35,000 | $1.2M |
| MetLife Investment Management, LLC | 0.01% | No change | 34,032 | $1.1M |
| Jane Street Group, LLC | 0.00% | Reduce -73.4% | 33,489 | $1.1M |
| Alps Advisors Inc. | 0.01% | Reduce -25.9% | 31,274 | $1.0M |
| Victory Capital Management Inc. | 0.00% | Add +234.9% | 29,414 | $978K |
| Brevan Howard Capital Management LP | 0.01% | New | 29,177 | $970K |
| Ensign Peak Advisors, Inc | 0.00% | Reduce -21.8% | 24,970 | $831K |
| Janus Henderson Group PLC | 0.00% | No change | 23,797 | $791K |
| Royal Bank of Canada | 0.00% | Reduce -30.3% | 23,164 | $770K |
| Intech Investment Management LLC | 0.01% | Reduce -35.4% | 22,793 | $758K |
| Savvy Advisors, Inc. | 0.05% | New | 21,781 | $724K |
| CANADA LIFE ASSURANCE Co | 0.00% | Add +1.3% | 19,663 | $654K |
| Handelsbanken Fonder AB | 0.00% | No change | 19,323 | $643K |
| FMR LLC | 0.00% | Add +4.4% | 18,592 | $618K |
| Guggenheim Capital LLC | 0.00% | Reduce -4.5% | 17,904 | $595K |
| Fox Run Management, L.L.C. | 0.10% | New | 17,707 | $589K |
| Thrivent Financial for Lutherans | 0.00% | No change | 17,526 | $583K |
| Caption Management, LLC | 0.05% | Reduce -75.7% | 17,000 | $565K |
| Arizona State Retirement System | 0.00% | Add +13.5% | 16,676 | $555K |
| Engineers Gate Manager LP | 0.01% | Reduce -27.2% | 16,548 | $550K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +27.7% | 16,396 | $545K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 15,847 | $527K |
| Tidal Investments LLC | 0.00% | Reduce -19.0% | 15,560 | $518K |
| Voya Investment Management LLC | 0.00% | Add +1.1% | 15,408 | $512K |
| Teacher Retirement System of Texas | 0.00% | Add +11.5% | 15,405 | $512K |
| Centiva Capital, LP | 0.03% | Add +0.1% | 15,040 | $500K |
| Hennion & Walsh Asset Management, Inc. | 0.02% | New | 15,005 | $499K |
| Polar Asset Management Partners Inc. | 0.02% | New | 14,700 | $489K |
| Henshaw Capital LLC | 0.02% | No change | 14,041 | $467K |
| ProShare Advisors LLC | 0.00% | Reduce -7.3% | 13,744 | $457K |
| Atria Investments, Inc | 0.01% | Reduce -7.7% | 13,473 | $448K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +7.4% | 12,923 | $430K |
| Virtus Investment Advisers, LLC | 0.14% | Add +36.9% | 12,881 | $428K |
| Creative Planning | 0.00% | Add +7.7% | 12,839 | $427K |
| Headlands Technologies LLC | 0.05% | Add +18.0% | 12,644 | $421K |
| BNP Paribas Financial Markets | 0.00% | Add +174.6% | 11,908 | $396K |
| KLP Kapitalforvaltning As | 0.00% | Add +18.0% | 11,800 | $392K |
| Inspire Investing, LLC | 0.04% | Reduce -0.3% | 11,728 | $390K |
| China Universal Asset Management Co., Ltd. | 0.04% | Add +1.2% | 11,632 | $387K |
| Gallagher Fiduciary Advisors, LLC | 0.01% | Reduce -10.6% | 11,473 | $382K |
| Profund Advisors LLC | 0.01% | Reduce -44.6% | 10,851 | $361K |
| Sei Investments Co. | 0.00% | Reduce -24.9% | 10,326 | $343K |
| Envestnet Asset Management Inc. | 0.00% | Reduce -55.2% | 10,100 | $336K |
| Commerce Bank | 0.00% | Add +17.1% | 9,604 | $319K |
| Russell Investments Group, Ltd. | 0.00% | Add +8.6% | 9,292 | $309K |
| Two Sigma Securities, LLC | 0.04% | New | 8,646 | $288K |
| Ieq Capital, LLC | 0.00% | New | 8,086 | $269K |
| Jain Global LLC | 0.00% | New | 7,749 | $258K |
| Cibc World Markets Corp. | 0.00% | Reduce -44.5% | 6,959 | $231K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 6,796 | $226K |
| Cerity Partners LLC | 0.00% | New | 6,789 | $226K |
| Norges Bank | 0.00% | Reduce -91.3% | 6,756 | $225K |
| Tower Research Capital LLC (TRC) | 0.01% | Add +634.3% | 6,440 | $214K |
| Ameritas Investment Partners, Inc. | 0.01% | No change | 5,913 | $197K |
| Cwm, LLC | 0.00% | Add +218.6% | 5,286 | $176K |
| PNC Financial Services Group, Inc. | 0.00% | Add +23.4% | 4,419 | $147K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +16.7% | 2,237 | $74K |
| BIT Capital GmbH | 0.00% | Reduce -89.6% | 2,230 | $74K |
| Amalgamated Bank | 0.00% | No change | 1,957 | $65K |
| Wilmington Savings Fund Society, FSB | 0.00% | Reduce -10.7% | 1,885 | $63K |
| KBC Group NV | 0.00% | Reduce -33.0% | 1,751 | $58K |
| Sterling Capital Management LLC | 0.00% | Add +55.4% | 1,515 | $50K |
| GF Fund Management Co. LTD. | 0.00% | No change | 1,460 | $49K |
| NewEdge Advisors, LLC | 0.00% | Reduce -6.0% | 1,273 | $42K |
| Brooklyn Investment Group | 0.00% | New | 1,130 | $38K |
| STRS Ohio | 0.00% | Reduce -86.6% | 1,100 | $37K |
| Assetmark, Inc. | 0.00% | Add +18.6% | 955 | $32K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -5.1% | 780 | $26K |
| AlphaQuest LLC | 0.00% | Add +79.4% | 669 | $22K |
| Federated Hermes, Inc. | 0.00% | Reduce -96.2% | 597 | $20K |
| US Bancorp \de | 0.00% | Add +1.8% | 569 | $19K |
| First Horizon Advisors, Inc. | 0.00% | Reduce -3.9% | 523 | $17K |
| Signaturefd, LLC | 0.00% | Add +7.5% | 513 | $17K |
| Lazard Asset Management LLC | 0.00% | Reduce -79.9% | 534 | $17K |
| Raymond James Financial Inc. | 0.00% | New | 442 | $15K |
| Hurley Capital, LLC | 0.01% | No change | 366 | $12K |
| Aspect Partners, LLC | 0.01% | No change | 361 | $12K |
| Comerica Bank | 0.00% | Add +85.8% | 353 | $12K |
| Osaic Holdings, Inc. | 0.00% | Add +891.4% | 347 | $12K |
| Lanark Financial, Inc. | 0.00% | No change | 345 | $11K |
| Versant Capital Management, Inc | 0.00% | New | 316 | $11K |
| Optiver Holding B.V. | 0.00% | Add +41.9% | 305 | $10K |
| Bell Investment Advisors, Inc | 0.00% | Add +25.7% | 298 | $10K |
| Clearstead Advisors, LLC | 0.00% | New | 291 | $10K |
| Spire Wealth Management | 0.00% | No change | 230 | $8K |
| Daiwa Securities Group Inc. | 0.00% | No change | 204 | $7K |
| Concord Wealth Partners | 0.00% | No change | 200 | $7K |
| Hillsdale Investment Management Inc. | 0.00% | No change | 200 | $7K |
| GAMMA Investing LLC | 0.00% | Reduce -34.4% | 183 | $6K |
| Smartleaf Asset Management LLC | 0.00% | Reduce -46.8% | 167 | $6K |
| Farther Finance Advisors, LLC | 0.00% | Add +1158.3% | 151 | $5K |
| Kestra Investment Management, LLC | 0.00% | No change | 139 | $5K |
| Bessemer Group Inc. | 0.00% | No change | 110 | $4K |
| Essential Partners LLC | 0.00% | — | 115 | $4K |
| Rothschild Investment LLC | 0.00% | Reduce -18.2% | 90 | $3K |
| Private Wealth Management Group, LLC | 0.00% | No change | 84 | $3K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +51.2% | 62 | $2K |
| Parkside Financial Bank & Trust | 0.00% | Add +50.0% | 45 | $1K |
| MAI Capital Management | 0.00% | Reduce -10.5% | 34 | $1K |
| Raffa Wealth Management, LLC | 0.00% | No change | 32 | $1K |
| Caitong International Asset Management Co., Ltd | 0.00% | Reduce -53.3% | 21 | $698 |
| JFS Wealth Advisors, LLC | 0.00% | Add +220.0% | 16 | $533 |
| Allworth Financial LP | 0.00% | Add +36.4% | 15 | $499 |
| Arax Advisory Partners | 0.00% | Reduce -35.0% | 13 | $432 |
| Parallel Advisors, LLC | 0.00% | Reduce -97.6% | 12 | $399 |
| True Wealth Design, LLC | 0.00% | Add +80.0% | 9 | $300 |
| Steward Partners Investment Advisory, LLC | 0.00% | No change | 9 | $299 |
| Fortitude Family Office, LLC | 0.00% | New | 5 | $166 |
| Riggs Asset Managment Co. Inc. | 0.00% | Reduce -92.7% | 3 | $100 |
| SBI Securities Co., Ltd. | 0.00% | No change | 3 | $100 |
| Rialto Wealth Management, LLC | 0.00% | New | 2 | $67 |
| Bay Harbor Wealth Management, LLC | 0.00% | Add +100.0% | 2 | $66 |
| SJS Investment Consulting Inc. | 0.00% | Reduce -50.0% | 1 | $34 |
| DiNuzzo Private Wealth, Inc. | 0.00% | Reduce -50.0% | 1 | $34 |
| Jones Financial Companies LLLP | 0.00% | New | 1 | $33 |
| HFM Investment Advisors, LLC | 0.00% | No change | 1 | $33 |
| Hemington Wealth Management | 0.00% | Reduce -71.4% | 6 | $0 |
| Covestor Ltd | 0.00% | No change | 3 | $0 |
"% of holder's portfolio" is AGIO's weight in each manager's 13F, not the share of Agios Pharmaceuticals Inc. the manager owns.