Agios PharmaceuticalsAGIO

13F holders, Q1 2026 (March 31)
234holders −4
29new positions
35sold out
5famous investors
$33.62avg. 13F price*

At the end of Q1 2026, 234 institutions reported holding Agios Pharmaceuticals Inc. (AGIO) in their 13F filings, down 4 from Q4 2025. 29 opened new positions and 35 sold out. The largest holders were BlackRock, Inc. ($194.7M), Farallon Capital Management, L.L.C. ($192.3M) and State Street Corp. ($113.7M). 5 famous investors held it, including David E. Shaw (0.1% of D. E. Shaw & Co.'s portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).

Company
Agios Pharmaceuticals Inc.
CUSIP
00847X104
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150200250 Q1 2024: 187Q1 2024Q2 2024: 206Q2 2024Q3 2024: 208Q3 2024Q4 2024: 225Q4 2024Q1 2025: 221Q1 2025Q2 2025: 215Q2 2025Q3 2025: 221Q3 2025Q4 2025: 238Q4 2025Q1 2026: 234Q1 2026Q2 2026: 238Q2 2026

Total Exit/New Position Q4 2025 → Q1 2026

InstitutionsTotal Value
New Positions29$41.0M
Exits35$68.4M

All 13F filers, Q4 2025 → Q1 2026: 10,474,127 shares bought and 8,697,575 shares sold, net +1,776,552 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 234 holders

BlackRock, Inc. 0.00% Add +9.9% 5,754,957 $194.7M
Farallon Capital Management, L.L.C. 1.15% Add +10.2% 5,684,000 $192.3M
State Street Corp. 0.00% Add +8.3% 3,364,879 $113.7M
Armistice Capital, LLC 3.03% Reduce -10.5% 2,716,000 $91.9M
D. E. Shaw & Co. 0.08% Add +45.9% 2,681,169 $90.7M
Vanguard Capital Management LLC 0.00% — 2,632,316 $89.1M
Lynx1 Capital Management LP 13.96% Add +3179.9% 2,611,568 $88.3M
Vanguard Portfolio Management LLC 0.00% — 2,611,035 $88.3M
Erste Asset Management GmbH 0.74% Reduce -3.6% 2,704,900 $80.1M
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.06% Add +16.2% 1,580,840 $53.5M
Nomura Asset Management International Inc. 0.09% Reduce -12.2% 1,494,435 $50.6M
T. Rowe Price Investment Management, Inc. 0.03% Add +166799.1% 1,488,740 $50.4M
Geode Capital Management, LLC 0.00% Add +3.9% 1,467,910 $49.7M
Susquehanna International Group, LLP 0.06% Add +17.7% 1,344,953 $45.5M
MPM Bioimpact LLC 3.41% Add +0.2% 1,306,261 $44.2M
Frazier Life Sciences Management, L.P. 1.10% Reduce -1.9% 1,256,080 $42.5M
GW&K Investment Management, LLC 0.36% Add +0.6% 1,214,901 $41.1M
Dimensional Fund Advisors LP 0.01% Add +14.7% 1,151,614 $38.9M
Morgan Stanley 0.00% Add +8.2% 967,525 $32.7M
Goldman Sachs Group Inc. 0.00% Reduce -22.1% 805,776 $27.3M
Rock Springs Capital Management LP 1.59% No change 799,163 $27.0M
Nuveen, LLC 0.01% Add +142.5% 722,348 $24.4M
Jane Street Group, LLC 0.03% Reduce -38.9% 685,240 $23.2M
Wellington Management Group LLP 0.00% Add +7.3% 641,486 $21.7M
Citadel Advisors 0.02% Reduce -54.1% 619,613 $21.0M
SCS Capital Management LLC 0.22% Add +2.4% 612,850 $20.7M
Foresite Capital Management VI LLC 3.86% Reduce -0.9% 525,000 $17.8M
Northern Trust Corp. 0.00% Reduce -0.5% 509,272 $17.2M
Bank of America Corp. 0.00% Reduce -5.8% 507,900 $17.2M
Artisan Partners Limited Partnership 0.03% Reduce -4.5% 481,516 $16.3M
Charles Schwab Investment Management Inc. 0.00% Reduce -1.2% 477,032 $16.1M
Connor, Clark & Lunn Investment Management Ltd. 0.04% Reduce -20.0% 450,093 $15.2M
Vestal Point Capital, LP 0.43% Add +38.5% 450,000 $15.2M
Marshall Wace, LLP 0.02% Add +26.7% 448,118 $15.2M
Legal & General Group Plc 0.00% Add +29.2% 423,915 $14.3M
ArrowMark Colorado Holdings LLC 0.36% Reduce -13.4% 403,590 $13.7M
Parkman Healthcare Partners LLC 1.42% Add +305.1% 403,525 $13.7M
Vanguard Fiduciary Trust Co. 0.00% — 382,021 $12.9M
BNP Paribas Financial Markets 0.01% Add +34.9% 327,457 $11.1M
T. Rowe Price Associates Inc. 0.00% Reduce -53.2% 298,783 $10.1M
Kennedy Capital Management LLC 0.20% Add +319.6% 275,456 $9.3M
Algert Global LLC 0.14% Reduce -35.2% 268,435 $9.1M
Two Sigma Investments, LP 0.01% Reduce -16.2% 251,636 $8.5M
Arrowstreet Capital, Limited Partnership 0.00% New 250,461 $8.5M
Panagora Asset Management Inc. 0.03% Add +198.7% 238,468 $8.1M
Palo Alto Investors LP 1.11% Add +0.5% 213,601 $7.2M
Seven Fleet Capital Management LP 2.23% Add +560.2% 209,547 $7.1M
Squarepoint Ops LLC 0.02% Add +71.5% 208,888 $7.1M
Schonfeld Strategic Advisors LLC 0.06% New 200,061 $6.8M
Eversept Partners, LP 0.45% New 200,000 $6.8M
HRT Financial LP 0.02% Add +33.4% 195,432 $6.6M
Qube Research & Technologies Ltd 0.01% Reduce -50.4% 187,667 $6.3M
Bank of New York Mellon Corp 0.00% Reduce -5.1% 186,791 $6.3M
Group One Trading LLC 0.19% Add +4.0% 173,279 $5.9M
Tetragon Partners GP Ltd 1.10% Add +1.7% 164,839 $5.6M
XTX Topco Ltd 0.09% Add +249.4% 160,880 $5.4M
Invesco Ltd. 0.00% Add +6.2% 151,430 $5.1M
Man Group plc 0.01% New 144,297 $4.9M
Edgestream Partners, L.P. 0.16% Reduce -14.4% 143,731 $4.9M
ADAR1 Capital Management, LLC 0.29% Reduce -25.2% 140,672 $4.8M
JPMorgan Chase & Co. 0.00% Reduce -39.8% 151,558 $4.5M
UBS Group AG 0.00% Add +4.6% 132,540 $4.5M
Capital Fund Management S.A. 0.04% Add +261.9% 129,531 $4.4M
Exome Asset Management LLC 2.49% Reduce -8.7% 125,060 $4.2M
American Century Companies Inc. 0.00% Reduce -20.6% 120,253 $4.1M
Pictet Asset Management Holding SA 0.00% Reduce -37.2% 128,814 $3.8M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% Add +3.4% 110,679 $3.7M
Swiss National Bank 0.00% No change 108,860 $3.7M
Essex Investment Management Co. LLC 0.55% New 103,177 $3.5M
Rafferty Asset Management, LLC 0.01% Reduce -4.4% 102,741 $3.5M
Tang Capital Management LLC 0.17% New 100,000 $3.4M
Knott David M Jr 1.87% Add +417.0% 93,058 $3.1M
Trexquant Investment LP 0.02% Reduce -66.8% 75,298 $2.5M
Woodline Partners LP 0.01% No change 74,423 $2.5M
Rhumbline Advisers 0.00% Reduce -1.1% 73,369 $2.5M
California State Teachers Retirement System 0.00% Add +28.8% 68,564 $2.3M
Assenagon Asset Management S.A. 0.00% Reduce -39.2% 67,153 $2.3M
Sei Investments Co. 0.00% Add +342.8% 63,550 $2.1M
Universal- Beteiligungs- und Servicegesellschaft mbH 0.00% Add +0.2% 60,679 $2.1M
Headlands Technologies LLC 0.23% Add +12.4% 59,257 $2.0M
VANGUARD ASSET MANAGEMENT, Ltd 0.00% — 58,648 $2.0M
Tudor Investment Corporation 0.01% Reduce -5.2% 58,151 $2.0M
SG Americas Securities, LLC 0.00% Add +23.2% 57,247 $1.9M
Barclays PLC 0.00% Reduce -83.6% 52,438 $1.8M
Hudson Bay Capital Management LP 0.01% Reduce -48.2% 51,830 $1.8M
New York State Common Retirement Fund 0.00% No change 51,707 $1.7M
Deutsche Bank AG 0.00% Reduce -59.0% 50,384 $1.7M
Manufacturers Life Insurance Company, The 0.00% Reduce -28.8% 50,046 $1.7M
Alliancebernstein L.P. 0.00% No change 61,494 $1.7M
Capital International Investors 0.00% Reduce -93.1% 48,616 $1.6M
Alps Advisors Inc. 0.01% Reduce -0.4% 47,701 $1.6M
Profund Advisors LLC 0.06% Add +14.9% 45,794 $1.5M
Harbor Capital Advisors, Inc. 0.12% Add +15.5% 43,005 $1.5M
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Add +6.6% 42,071 $1.4M
Russell Investments Group, Ltd. 0.00% Add +60.9% 39,710 $1.3M
VIRGINIA RETIREMENT SYSTEMS ET Al 0.01% Reduce -5.6% 39,061 $1.3M
Simplex Trading, LLC 0.04% Add +503.4% 37,462 $1.3M
Gsa Capital Partners LLP 0.08% New 36,472 $1.2M
AQR Capital Management 0.00% Add +30.4% 36,410 $1.2M
Martingale Asset Management L P 0.03% New 35,814 $1.2M
Edgewood Management LLC 0.01% No change 35,000 $1.2M
Hennion & Walsh Asset Management, Inc. 0.04% Add +1.2% 33,868 $1.1M
MetLife Investment Management, LLC 0.01% Add +2.0% 32,858 $1.1M
Legato Capital Management LLC 0.10% New 32,373 $1.1M
Millennium Management 0.00% Reduce -91.9% 32,144 $1.1M
Virtus Investment Advisers, LLC 0.29% Add +23.5% 30,959 $1.0M
Prelude Capital Management, LLC 0.08% Reduce -13.7% 29,085 $984K
Engineers Gate Manager LP 0.01% Reduce -41.1% 28,920 $978K
Jacobs Levy Equity Management, Inc. 0.00% Reduce -74.3% 28,530 $965K
State of Wisconsin Investment Board 0.00% Reduce -19.7% 27,810 $941K
Quantinno Capital Management LP 0.00% Add +2.7% 27,591 $933K
Brevan Howard Capital Management LP 0.01% Add +26.6% 24,469 $867K
Oak Ridge Investments LLC 0.06% Add +24.3% 24,865 $841K
Canada Pension Plan Investment Board 0.00% Add +34.1% 24,400 $825K
Janus Henderson Group PLC 0.00% No change 23,797 $805K
TD Asset Management Inc 0.00% Reduce -58.6% 23,732 $803K
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% No change 23,620 $799K
Vanguard Global Advisers, LLC 0.00% — 23,352 $790K
Wells Fargo & Company 0.00% Reduce -64.9% 22,763 $770K
Virtu Financial LLC 0.03% New 21,392 $724K
Handelsbanken Fonder AB 0.00% No change 19,323 $654K
Victory Capital Management Inc. 0.00% Reduce -31.0% 19,115 $647K
State of New Jersey Common Pension Fund D 0.00% Reduce -60.2% 18,864 $638K
Balyasny Asset Management L.P. 0.00% Reduce -97.2% 18,009 $609K
CenterBook Partners LP 0.03% New 17,445 $590K
Citigroup Inc. 0.00% Reduce -80.6% 17,096 $578K
Caitong International Asset Management Co., Ltd 0.10% Add +140.7% 16,222 $549K
State Board of Administration of Florida Retirement System 0.00% No change 15,847 $536K
Police & Firemen's Retirement System of New Jersey 0.00% No change 15,640 $529K
Diversified Trust Co. 0.01% Add +67.2% 15,319 $518K
Arizona State Retirement System 0.00% Reduce -1.1% 15,161 $513K
PSP Research LLC 0.36% New 15,000 $507K
Rockefeller Capital Management L.P. 0.00% Reduce -29.4% 14,875 $503K
Inspire Investing, LLC 0.03% Reduce -13.9% 14,740 $499K
Tidal Investments LLC 0.00% Add +0.9% 14,376 $486K
Intech Investment Management LLC 0.00% Reduce -49.6% 14,029 $475K
AlphaCentric Advisors LLC 0.47% Add +6.3% 13,971 $473K
Atria Investments, Inc 0.01% Reduce -1.3% 13,877 $469K
Y-Intercept (Hong Kong) Ltd 0.01% Reduce -82.6% 13,866 $469K
Pale Fire Capital SE 0.04% Add +15.2% 13,650 $462K
Vanguard Investments Australia, Ltd. 0.00% — 13,537 $458K
Creative Planning 0.00% Add +28.6% 13,333 $451K
E Fund Management Co., Ltd. 0.01% — 12,915 $437K
Commerce Bank 0.00% Reduce -1.7% 12,437 $421K
Caption Management, LLC 0.02% Reduce -86.8% 12,349 $418K
Envestnet Asset Management Inc. 0.00% Reduce -4.0% 12,228 $414K
KLP Kapitalforvaltning As 0.00% No change 11,800 $399K
Royal Bank of Canada 0.00% Reduce -9.7% 11,790 $399K
Aquatic Capital Management LLC 0.01% Reduce -68.6% 11,322 $383K
Gallagher Fiduciary Advisors, LLC 0.01% Reduce -1.5% 11,077 $375K
ProShare Advisors LLC 0.00% Reduce -16.2% 10,805 $366K
CANADA LIFE ASSURANCE Co 0.00% Add +2.4% 10,684 $362K
China Universal Asset Management Co., Ltd. 0.03% Add +9.4% 10,398 $352K
Voya Investment Management LLC 0.00% Reduce -1.4% 9,996 $338K
Voleon Capital Management LP 0.01% New 9,679 $327K
Nomura Holdings Inc. 0.00% Reduce -25.7% 9,176 $310K
FMR LLC 0.00% Reduce -62.5% 9,121 $309K
Prudential Financial Inc. 0.00% Reduce -88.8% 9,045 $306K
Inscription Capital, LLC 0.03% No change 8,595 $291K
Tower Research Capital LLC (TRC) 0.01% Add +26.9% 8,417 $285K
Ground Swell Capital, LLC 0.58% New 8,347 $282K
Franklin Resources Inc. 0.00% New 8,287 $280K
Fiduciary Trust Co 0.00% No change 8,247 $279K
PDT Partners, LLC 0.01% New 7,500 $254K
Teacher Retirement System of Texas 0.00% Reduce -12.7% 7,127 $241K
Public Employees Retirement Association of Colorado 0.00% No change 6,796 $230K
Savvy Advisors, Inc. 0.01% New 6,794 $230K
Ensign Peak Advisors, Inc 0.00% No change 6,570 $222K
Bridgefront Capital, LLC 0.06% Reduce -48.2% 6,551 $222K
Magnetar Financial LLC 0.00% New 5,936 $201K
Acadian Asset Management LLC 0.00% New 5,859 $196K
State of Alaska, Department of Revenue 0.00% No change 5,000 $169K
PNC Financial Services Group, Inc. 0.00% Add +4.9% 4,940 $167K
Ameritas Investment Partners, Inc. 0.00% No change 4,719 $160K
Jones Financial Companies LLLP 0.00% Add +404300.0% 4,044 $119K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +7.8% 3,056 $103K
Bayforest Capital Ltd 0.11% New 2,815 $95K
Eurizon Capital SGR S.p.A. 0.00% No change 2,647 $79K
KBC Group NV 0.00% Reduce -31.4% 2,073 $70K
Sterling Capital Management LLC 0.00% Reduce -43.0% 1,871 $63K
Osaic Holdings, Inc. 0.00% Add +2.2% 1,786 $60K
Assetmark, Inc. 0.00% No change 1,317 $45K
GF Fund Management Co. LTD. 0.00% Add +14.4% 1,310 $44K
Cwm, LLC 0.00% Add +164.7% 1,281 $43K
Los Angeles Capital Management LLC 0.00% Add +216.7% 950 $32K
GAMMA Investing LLC 0.00% Add +301.8% 687 $23K
First Horizon Corp. 0.00% Reduce -79.2% 643 $22K
US Bancorp \de 0.00% Add +6.5% 542 $18K
Nisa Investment Advisors, LLC 0.00% Add +73.9% 513 $17K
City Holding Co. 0.00% No change 500 $17K
Kemnay Advisory Services Inc. 0.00% New 477 $16K
Versant Capital Management, Inc 0.00% Add +354.4% 418 $14K
Summit Securities Group LLC 0.01% New 408 $14K
Signaturefd, LLC 0.00% No change 399 $13K
Smartleaf Asset Management LLC 0.00% Reduce -7.8% 424 $13K
Advisory Services Network, LLC 0.00% New 350 $12K
Thurston, Springer, Miller, Herd & Titak, Inc. 0.00% No change 241 $8K
Bell Investment Advisors, Inc 0.00% Reduce -15.7% 237 $8K
Fifth Third Bancorp 0.00% New 209 $7K
Farther Finance Advisors, LLC 0.00% Add +33.8% 202 $7K
Hillsdale Investment Management Inc. 0.00% No change 200 $7K
Keating Financial Advisory Services, Inc. 0.00% Add +581.0% 143 $5K
Arax Advisory Partners 0.00% Add +51.9% 120 $4K
Hurley Capital, LLC 0.00% Reduce -75.3% 120 $4K
Optiver Holding B.V. 0.00% New 108 $4K
Triumph Capital Management 0.00% No change 100 $3K
Bessemer Group Inc. 0.00% No change 76 $3K
Private Wealth Management Group, LLC 0.00% No change 83 $3K
JPL Wealth Management, LLC 0.00% New 70 $2K
Allworth Financial LP 0.00% Add +518.2% 68 $2K
Larson Financial Group LLC 0.00% New 66 $2K
Parkside Financial Bank & Trust 0.00% Add +313.3% 62 $2K
EverSource Wealth Advisors, LLC 0.00% Add +35.3% 46 $2K
Root Financial Partners, LLC 0.00% Reduce -33.3% 44 $1K
Rothschild Investment LLC 0.00% Add +700.0% 40 $1K
Pinnacle Wealth Planning Services, Inc. 0.00% No change 40 $1K
MAI Capital Management 0.00% New 37 $1K
SBI Securities Co., Ltd. 0.00% Add +725.0% 33 $1K
Raffa Wealth Management, LLC 0.00% No change 32 $1K
Parallel Advisors, LLC 0.00% Add +66.7% 20 $677
Federated Hermes, Inc. 0.00% Reduce -99.9% 19 $643
Manchester Capital Management LLC 0.00% No change 16 $542
Quadrant Capital Group LLC 0.00% No change 16 $542
True Wealth Design, LLC 0.00% New 12 $406
Steward Partners Investment Advisory, LLC 0.00% No change 9 $304
Essential Partners LLC 0.00% No change 5 $169
JFS Wealth Advisors, LLC 0.00% Reduce -50.0% 2 $68
IFP Advisors, Inc 0.00% Reduce -66.7% 2 $68
Fortitude Family Office, LLC 0.00% Reduce -60.0% 2 $68
Bay Harbor Wealth Management, LLC 0.00% Reduce -50.0% 2 $67
Dunhill Financial, LLC 0.00% Reduce -50.0% 1 $61
SJS Investment Consulting Inc. 0.00% No change 1 $34
Rialto Wealth Management, LLC 0.00% Reduce -50.0% 1 $34
Covestor Ltd 0.00% Reduce -92.7% 3 $0

"% of holder's portfolio" is AGIO's weight in each manager's 13F, not the share of Agios Pharmaceuticals Inc. the manager owns.