Agios PharmaceuticalsAGIO
13F holders, Q1 2026 (March 31)At the end of Q1 2026, 234 institutions reported holding Agios Pharmaceuticals Inc. (AGIO) in their 13F filings, down 4 from Q4 2025. 29 opened new positions and 35 sold out. The largest holders were BlackRock, Inc. ($194.7M), Farallon Capital Management, L.L.C. ($192.3M) and State Street Corp. ($113.7M). 5 famous investors held it, including David E. Shaw (0.1% of D. E. Shaw & Co.'s portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).
- Company
- Agios Pharmaceuticals Inc.
- CUSIP
- 00847X104
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 29 | $41.0M |
| Exits | 35 | $68.4M |
All 13F filers, Q4 2025 → Q1 2026: 10,474,127 shares bought and 8,697,575 shares sold, net +1,776,552 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 234 holders
| BlackRock, Inc. | 0.00% | Add +9.9% | 5,754,957 | $194.7M |
| Farallon Capital Management, L.L.C. | 1.15% | Add +10.2% | 5,684,000 | $192.3M |
| State Street Corp. | 0.00% | Add +8.3% | 3,364,879 | $113.7M |
| Armistice Capital, LLC | 3.03% | Reduce -10.5% | 2,716,000 | $91.9M |
| D. E. Shaw & Co. | 0.08% | Add +45.9% | 2,681,169 | $90.7M |
| Vanguard Capital Management LLC | 0.00% | — | 2,632,316 | $89.1M |
| Lynx1 Capital Management LP | 13.96% | Add +3179.9% | 2,611,568 | $88.3M |
| Vanguard Portfolio Management LLC | 0.00% | — | 2,611,035 | $88.3M |
| Erste Asset Management GmbH | 0.74% | Reduce -3.6% | 2,704,900 | $80.1M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.06% | Add +16.2% | 1,580,840 | $53.5M |
| Nomura Asset Management International Inc. | 0.09% | Reduce -12.2% | 1,494,435 | $50.6M |
| T. Rowe Price Investment Management, Inc. | 0.03% | Add +166799.1% | 1,488,740 | $50.4M |
| Geode Capital Management, LLC | 0.00% | Add +3.9% | 1,467,910 | $49.7M |
| Susquehanna International Group, LLP | 0.06% | Add +17.7% | 1,344,953 | $45.5M |
| MPM Bioimpact LLC | 3.41% | Add +0.2% | 1,306,261 | $44.2M |
| Frazier Life Sciences Management, L.P. | 1.10% | Reduce -1.9% | 1,256,080 | $42.5M |
| GW&K Investment Management, LLC | 0.36% | Add +0.6% | 1,214,901 | $41.1M |
| Dimensional Fund Advisors LP | 0.01% | Add +14.7% | 1,151,614 | $38.9M |
| Morgan Stanley | 0.00% | Add +8.2% | 967,525 | $32.7M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -22.1% | 805,776 | $27.3M |
| Rock Springs Capital Management LP | 1.59% | No change | 799,163 | $27.0M |
| Nuveen, LLC | 0.01% | Add +142.5% | 722,348 | $24.4M |
| Jane Street Group, LLC | 0.03% | Reduce -38.9% | 685,240 | $23.2M |
| Wellington Management Group LLP | 0.00% | Add +7.3% | 641,486 | $21.7M |
| Citadel Advisors | 0.02% | Reduce -54.1% | 619,613 | $21.0M |
| SCS Capital Management LLC | 0.22% | Add +2.4% | 612,850 | $20.7M |
| Foresite Capital Management VI LLC | 3.86% | Reduce -0.9% | 525,000 | $17.8M |
| Northern Trust Corp. | 0.00% | Reduce -0.5% | 509,272 | $17.2M |
| Bank of America Corp. | 0.00% | Reduce -5.8% | 507,900 | $17.2M |
| Artisan Partners Limited Partnership | 0.03% | Reduce -4.5% | 481,516 | $16.3M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -1.2% | 477,032 | $16.1M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.04% | Reduce -20.0% | 450,093 | $15.2M |
| Vestal Point Capital, LP | 0.43% | Add +38.5% | 450,000 | $15.2M |
| Marshall Wace, LLP | 0.02% | Add +26.7% | 448,118 | $15.2M |
| Legal & General Group Plc | 0.00% | Add +29.2% | 423,915 | $14.3M |
| ArrowMark Colorado Holdings LLC | 0.36% | Reduce -13.4% | 403,590 | $13.7M |
| Parkman Healthcare Partners LLC | 1.42% | Add +305.1% | 403,525 | $13.7M |
| Vanguard Fiduciary Trust Co. | 0.00% | — | 382,021 | $12.9M |
| BNP Paribas Financial Markets | 0.01% | Add +34.9% | 327,457 | $11.1M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -53.2% | 298,783 | $10.1M |
| Kennedy Capital Management LLC | 0.20% | Add +319.6% | 275,456 | $9.3M |
| Algert Global LLC | 0.14% | Reduce -35.2% | 268,435 | $9.1M |
| Two Sigma Investments, LP | 0.01% | Reduce -16.2% | 251,636 | $8.5M |
| Arrowstreet Capital, Limited Partnership | 0.00% | New | 250,461 | $8.5M |
| Panagora Asset Management Inc. | 0.03% | Add +198.7% | 238,468 | $8.1M |
| Palo Alto Investors LP | 1.11% | Add +0.5% | 213,601 | $7.2M |
| Seven Fleet Capital Management LP | 2.23% | Add +560.2% | 209,547 | $7.1M |
| Squarepoint Ops LLC | 0.02% | Add +71.5% | 208,888 | $7.1M |
| Schonfeld Strategic Advisors LLC | 0.06% | New | 200,061 | $6.8M |
| Eversept Partners, LP | 0.45% | New | 200,000 | $6.8M |
| HRT Financial LP | 0.02% | Add +33.4% | 195,432 | $6.6M |
| Qube Research & Technologies Ltd | 0.01% | Reduce -50.4% | 187,667 | $6.3M |
| Bank of New York Mellon Corp | 0.00% | Reduce -5.1% | 186,791 | $6.3M |
| Group One Trading LLC | 0.19% | Add +4.0% | 173,279 | $5.9M |
| Tetragon Partners GP Ltd | 1.10% | Add +1.7% | 164,839 | $5.6M |
| XTX Topco Ltd | 0.09% | Add +249.4% | 160,880 | $5.4M |
| Invesco Ltd. | 0.00% | Add +6.2% | 151,430 | $5.1M |
| Man Group plc | 0.01% | New | 144,297 | $4.9M |
| Edgestream Partners, L.P. | 0.16% | Reduce -14.4% | 143,731 | $4.9M |
| ADAR1 Capital Management, LLC | 0.29% | Reduce -25.2% | 140,672 | $4.8M |
| JPMorgan Chase & Co. | 0.00% | Reduce -39.8% | 151,558 | $4.5M |
| UBS Group AG | 0.00% | Add +4.6% | 132,540 | $4.5M |
| Capital Fund Management S.A. | 0.04% | Add +261.9% | 129,531 | $4.4M |
| Exome Asset Management LLC | 2.49% | Reduce -8.7% | 125,060 | $4.2M |
| American Century Companies Inc. | 0.00% | Reduce -20.6% | 120,253 | $4.1M |
| Pictet Asset Management Holding SA | 0.00% | Reduce -37.2% | 128,814 | $3.8M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +3.4% | 110,679 | $3.7M |
| Swiss National Bank | 0.00% | No change | 108,860 | $3.7M |
| Essex Investment Management Co. LLC | 0.55% | New | 103,177 | $3.5M |
| Rafferty Asset Management, LLC | 0.01% | Reduce -4.4% | 102,741 | $3.5M |
| Tang Capital Management LLC | 0.17% | New | 100,000 | $3.4M |
| Knott David M Jr | 1.87% | Add +417.0% | 93,058 | $3.1M |
| Trexquant Investment LP | 0.02% | Reduce -66.8% | 75,298 | $2.5M |
| Woodline Partners LP | 0.01% | No change | 74,423 | $2.5M |
| Rhumbline Advisers | 0.00% | Reduce -1.1% | 73,369 | $2.5M |
| California State Teachers Retirement System | 0.00% | Add +28.8% | 68,564 | $2.3M |
| Assenagon Asset Management S.A. | 0.00% | Reduce -39.2% | 67,153 | $2.3M |
| Sei Investments Co. | 0.00% | Add +342.8% | 63,550 | $2.1M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | Add +0.2% | 60,679 | $2.1M |
| Headlands Technologies LLC | 0.23% | Add +12.4% | 59,257 | $2.0M |
| VANGUARD ASSET MANAGEMENT, Ltd | 0.00% | — | 58,648 | $2.0M |
| Tudor Investment Corporation | 0.01% | Reduce -5.2% | 58,151 | $2.0M |
| SG Americas Securities, LLC | 0.00% | Add +23.2% | 57,247 | $1.9M |
| Barclays PLC | 0.00% | Reduce -83.6% | 52,438 | $1.8M |
| Hudson Bay Capital Management LP | 0.01% | Reduce -48.2% | 51,830 | $1.8M |
| New York State Common Retirement Fund | 0.00% | No change | 51,707 | $1.7M |
| Deutsche Bank AG | 0.00% | Reduce -59.0% | 50,384 | $1.7M |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -28.8% | 50,046 | $1.7M |
| Alliancebernstein L.P. | 0.00% | No change | 61,494 | $1.7M |
| Capital International Investors | 0.00% | Reduce -93.1% | 48,616 | $1.6M |
| Alps Advisors Inc. | 0.01% | Reduce -0.4% | 47,701 | $1.6M |
| Profund Advisors LLC | 0.06% | Add +14.9% | 45,794 | $1.5M |
| Harbor Capital Advisors, Inc. | 0.12% | Add +15.5% | 43,005 | $1.5M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +6.6% | 42,071 | $1.4M |
| Russell Investments Group, Ltd. | 0.00% | Add +60.9% | 39,710 | $1.3M |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 0.01% | Reduce -5.6% | 39,061 | $1.3M |
| Simplex Trading, LLC | 0.04% | Add +503.4% | 37,462 | $1.3M |
| Gsa Capital Partners LLP | 0.08% | New | 36,472 | $1.2M |
| AQR Capital Management | 0.00% | Add +30.4% | 36,410 | $1.2M |
| Martingale Asset Management L P | 0.03% | New | 35,814 | $1.2M |
| Edgewood Management LLC | 0.01% | No change | 35,000 | $1.2M |
| Hennion & Walsh Asset Management, Inc. | 0.04% | Add +1.2% | 33,868 | $1.1M |
| MetLife Investment Management, LLC | 0.01% | Add +2.0% | 32,858 | $1.1M |
| Legato Capital Management LLC | 0.10% | New | 32,373 | $1.1M |
| Millennium Management | 0.00% | Reduce -91.9% | 32,144 | $1.1M |
| Virtus Investment Advisers, LLC | 0.29% | Add +23.5% | 30,959 | $1.0M |
| Prelude Capital Management, LLC | 0.08% | Reduce -13.7% | 29,085 | $984K |
| Engineers Gate Manager LP | 0.01% | Reduce -41.1% | 28,920 | $978K |
| Jacobs Levy Equity Management, Inc. | 0.00% | Reduce -74.3% | 28,530 | $965K |
| State of Wisconsin Investment Board | 0.00% | Reduce -19.7% | 27,810 | $941K |
| Quantinno Capital Management LP | 0.00% | Add +2.7% | 27,591 | $933K |
| Brevan Howard Capital Management LP | 0.01% | Add +26.6% | 24,469 | $867K |
| Oak Ridge Investments LLC | 0.06% | Add +24.3% | 24,865 | $841K |
| Canada Pension Plan Investment Board | 0.00% | Add +34.1% | 24,400 | $825K |
| Janus Henderson Group PLC | 0.00% | No change | 23,797 | $805K |
| TD Asset Management Inc | 0.00% | Reduce -58.6% | 23,732 | $803K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | No change | 23,620 | $799K |
| Vanguard Global Advisers, LLC | 0.00% | — | 23,352 | $790K |
| Wells Fargo & Company | 0.00% | Reduce -64.9% | 22,763 | $770K |
| Virtu Financial LLC | 0.03% | New | 21,392 | $724K |
| Handelsbanken Fonder AB | 0.00% | No change | 19,323 | $654K |
| Victory Capital Management Inc. | 0.00% | Reduce -31.0% | 19,115 | $647K |
| State of New Jersey Common Pension Fund D | 0.00% | Reduce -60.2% | 18,864 | $638K |
| Balyasny Asset Management L.P. | 0.00% | Reduce -97.2% | 18,009 | $609K |
| CenterBook Partners LP | 0.03% | New | 17,445 | $590K |
| Citigroup Inc. | 0.00% | Reduce -80.6% | 17,096 | $578K |
| Caitong International Asset Management Co., Ltd | 0.10% | Add +140.7% | 16,222 | $549K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 15,847 | $536K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 15,640 | $529K |
| Diversified Trust Co. | 0.01% | Add +67.2% | 15,319 | $518K |
| Arizona State Retirement System | 0.00% | Reduce -1.1% | 15,161 | $513K |
| PSP Research LLC | 0.36% | New | 15,000 | $507K |
| Rockefeller Capital Management L.P. | 0.00% | Reduce -29.4% | 14,875 | $503K |
| Inspire Investing, LLC | 0.03% | Reduce -13.9% | 14,740 | $499K |
| Tidal Investments LLC | 0.00% | Add +0.9% | 14,376 | $486K |
| Intech Investment Management LLC | 0.00% | Reduce -49.6% | 14,029 | $475K |
| AlphaCentric Advisors LLC | 0.47% | Add +6.3% | 13,971 | $473K |
| Atria Investments, Inc | 0.01% | Reduce -1.3% | 13,877 | $469K |
| Y-Intercept (Hong Kong) Ltd | 0.01% | Reduce -82.6% | 13,866 | $469K |
| Pale Fire Capital SE | 0.04% | Add +15.2% | 13,650 | $462K |
| Vanguard Investments Australia, Ltd. | 0.00% | — | 13,537 | $458K |
| Creative Planning | 0.00% | Add +28.6% | 13,333 | $451K |
| E Fund Management Co., Ltd. | 0.01% | — | 12,915 | $437K |
| Commerce Bank | 0.00% | Reduce -1.7% | 12,437 | $421K |
| Caption Management, LLC | 0.02% | Reduce -86.8% | 12,349 | $418K |
| Envestnet Asset Management Inc. | 0.00% | Reduce -4.0% | 12,228 | $414K |
| KLP Kapitalforvaltning As | 0.00% | No change | 11,800 | $399K |
| Royal Bank of Canada | 0.00% | Reduce -9.7% | 11,790 | $399K |
| Aquatic Capital Management LLC | 0.01% | Reduce -68.6% | 11,322 | $383K |
| Gallagher Fiduciary Advisors, LLC | 0.01% | Reduce -1.5% | 11,077 | $375K |
| ProShare Advisors LLC | 0.00% | Reduce -16.2% | 10,805 | $366K |
| CANADA LIFE ASSURANCE Co | 0.00% | Add +2.4% | 10,684 | $362K |
| China Universal Asset Management Co., Ltd. | 0.03% | Add +9.4% | 10,398 | $352K |
| Voya Investment Management LLC | 0.00% | Reduce -1.4% | 9,996 | $338K |
| Voleon Capital Management LP | 0.01% | New | 9,679 | $327K |
| Nomura Holdings Inc. | 0.00% | Reduce -25.7% | 9,176 | $310K |
| FMR LLC | 0.00% | Reduce -62.5% | 9,121 | $309K |
| Prudential Financial Inc. | 0.00% | Reduce -88.8% | 9,045 | $306K |
| Inscription Capital, LLC | 0.03% | No change | 8,595 | $291K |
| Tower Research Capital LLC (TRC) | 0.01% | Add +26.9% | 8,417 | $285K |
| Ground Swell Capital, LLC | 0.58% | New | 8,347 | $282K |
| Franklin Resources Inc. | 0.00% | New | 8,287 | $280K |
| Fiduciary Trust Co | 0.00% | No change | 8,247 | $279K |
| PDT Partners, LLC | 0.01% | New | 7,500 | $254K |
| Teacher Retirement System of Texas | 0.00% | Reduce -12.7% | 7,127 | $241K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 6,796 | $230K |
| Savvy Advisors, Inc. | 0.01% | New | 6,794 | $230K |
| Ensign Peak Advisors, Inc | 0.00% | No change | 6,570 | $222K |
| Bridgefront Capital, LLC | 0.06% | Reduce -48.2% | 6,551 | $222K |
| Magnetar Financial LLC | 0.00% | New | 5,936 | $201K |
| Acadian Asset Management LLC | 0.00% | New | 5,859 | $196K |
| State of Alaska, Department of Revenue | 0.00% | No change | 5,000 | $169K |
| PNC Financial Services Group, Inc. | 0.00% | Add +4.9% | 4,940 | $167K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 4,719 | $160K |
| Jones Financial Companies LLLP | 0.00% | Add +404300.0% | 4,044 | $119K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +7.8% | 3,056 | $103K |
| Bayforest Capital Ltd | 0.11% | New | 2,815 | $95K |
| Eurizon Capital SGR S.p.A. | 0.00% | No change | 2,647 | $79K |
| KBC Group NV | 0.00% | Reduce -31.4% | 2,073 | $70K |
| Sterling Capital Management LLC | 0.00% | Reduce -43.0% | 1,871 | $63K |
| Osaic Holdings, Inc. | 0.00% | Add +2.2% | 1,786 | $60K |
| Assetmark, Inc. | 0.00% | No change | 1,317 | $45K |
| GF Fund Management Co. LTD. | 0.00% | Add +14.4% | 1,310 | $44K |
| Cwm, LLC | 0.00% | Add +164.7% | 1,281 | $43K |
| Los Angeles Capital Management LLC | 0.00% | Add +216.7% | 950 | $32K |
| GAMMA Investing LLC | 0.00% | Add +301.8% | 687 | $23K |
| First Horizon Corp. | 0.00% | Reduce -79.2% | 643 | $22K |
| US Bancorp \de | 0.00% | Add +6.5% | 542 | $18K |
| Nisa Investment Advisors, LLC | 0.00% | Add +73.9% | 513 | $17K |
| City Holding Co. | 0.00% | No change | 500 | $17K |
| Kemnay Advisory Services Inc. | 0.00% | New | 477 | $16K |
| Versant Capital Management, Inc | 0.00% | Add +354.4% | 418 | $14K |
| Summit Securities Group LLC | 0.01% | New | 408 | $14K |
| Signaturefd, LLC | 0.00% | No change | 399 | $13K |
| Smartleaf Asset Management LLC | 0.00% | Reduce -7.8% | 424 | $13K |
| Advisory Services Network, LLC | 0.00% | New | 350 | $12K |
| Thurston, Springer, Miller, Herd & Titak, Inc. | 0.00% | No change | 241 | $8K |
| Bell Investment Advisors, Inc | 0.00% | Reduce -15.7% | 237 | $8K |
| Fifth Third Bancorp | 0.00% | New | 209 | $7K |
| Farther Finance Advisors, LLC | 0.00% | Add +33.8% | 202 | $7K |
| Hillsdale Investment Management Inc. | 0.00% | No change | 200 | $7K |
| Keating Financial Advisory Services, Inc. | 0.00% | Add +581.0% | 143 | $5K |
| Arax Advisory Partners | 0.00% | Add +51.9% | 120 | $4K |
| Hurley Capital, LLC | 0.00% | Reduce -75.3% | 120 | $4K |
| Optiver Holding B.V. | 0.00% | New | 108 | $4K |
| Triumph Capital Management | 0.00% | No change | 100 | $3K |
| Bessemer Group Inc. | 0.00% | No change | 76 | $3K |
| Private Wealth Management Group, LLC | 0.00% | No change | 83 | $3K |
| JPL Wealth Management, LLC | 0.00% | New | 70 | $2K |
| Allworth Financial LP | 0.00% | Add +518.2% | 68 | $2K |
| Larson Financial Group LLC | 0.00% | New | 66 | $2K |
| Parkside Financial Bank & Trust | 0.00% | Add +313.3% | 62 | $2K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +35.3% | 46 | $2K |
| Root Financial Partners, LLC | 0.00% | Reduce -33.3% | 44 | $1K |
| Rothschild Investment LLC | 0.00% | Add +700.0% | 40 | $1K |
| Pinnacle Wealth Planning Services, Inc. | 0.00% | No change | 40 | $1K |
| MAI Capital Management | 0.00% | New | 37 | $1K |
| SBI Securities Co., Ltd. | 0.00% | Add +725.0% | 33 | $1K |
| Raffa Wealth Management, LLC | 0.00% | No change | 32 | $1K |
| Parallel Advisors, LLC | 0.00% | Add +66.7% | 20 | $677 |
| Federated Hermes, Inc. | 0.00% | Reduce -99.9% | 19 | $643 |
| Manchester Capital Management LLC | 0.00% | No change | 16 | $542 |
| Quadrant Capital Group LLC | 0.00% | No change | 16 | $542 |
| True Wealth Design, LLC | 0.00% | New | 12 | $406 |
| Steward Partners Investment Advisory, LLC | 0.00% | No change | 9 | $304 |
| Essential Partners LLC | 0.00% | No change | 5 | $169 |
| JFS Wealth Advisors, LLC | 0.00% | Reduce -50.0% | 2 | $68 |
| IFP Advisors, Inc | 0.00% | Reduce -66.7% | 2 | $68 |
| Fortitude Family Office, LLC | 0.00% | Reduce -60.0% | 2 | $68 |
| Bay Harbor Wealth Management, LLC | 0.00% | Reduce -50.0% | 2 | $67 |
| Dunhill Financial, LLC | 0.00% | Reduce -50.0% | 1 | $61 |
| SJS Investment Consulting Inc. | 0.00% | No change | 1 | $34 |
| Rialto Wealth Management, LLC | 0.00% | Reduce -50.0% | 1 | $34 |
| Covestor Ltd | 0.00% | Reduce -92.7% | 3 | $0 |
"% of holder's portfolio" is AGIO's weight in each manager's 13F, not the share of Agios Pharmaceuticals Inc. the manager owns.