AnaptysbioANAB

13F holders, Q3 2025 (September 30)
166holders +19
34new positions
14sold out
8famous investors
$30.95avg. 13F price*

At the end of Q3 2025, 166 institutions reported holding Anaptysbio Inc. (ANAB) in their 13F filings, up 19 from Q2 2025. 34 opened new positions and 14 sold out. The largest holders were EcoR1 Capital, LLC ($241.3M), Point72 Asset Management ($69.4M) and BlackRock, Inc. ($52.7M). 8 famous investors held it, including Steve Cohen (0.2% of Point72 Asset Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio).

Company
Anaptysbio Inc.
CUSIP
032724106
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150200250 Q1 2024: 133Q1 2024Q2 2024: 135Q2 2024Q3 2024: 160Q3 2024Q4 2024: 135Q4 2024Q1 2025: 153Q1 2025Q2 2025: 147Q2 2025Q3 2025: 166Q3 2025Q4 2025: 179Q4 2025Q1 2026: 208Q1 2026Q2 2026: 213Q2 2026

Total Exit/New Position Q2 2025 → Q3 2025

InstitutionsTotal Value
New Positions34$15.1M
Exits14$5.8M

All 13F filers, Q2 2025 → Q3 2025: 4,518,050 shares bought and 9,471,191 shares sold, net −4,953,141 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 166 holders

EcoR1 Capital, LLC 11.60% No change 7,880,094 $241.3M
Point72 Asset Management 0.16% Reduce -8.5% 2,265,528 $69.4M
BlackRock, Inc. 0.00% Reduce -3.6% 1,722,324 $52.7M
Morgan Stanley 0.00% Reduce -16.8% 1,556,258 $47.7M
Millennium Management 0.04% Add +646.4% 1,519,230 $46.5M
Vanguard Group Inc. 0.00% Reduce -3.9% 1,476,989 $45.2M
Tang Capital Management LLC 1.57% Add +0.2% 1,333,639 $40.8M
First Light Asset Management, LLC 2.86% Reduce -72.0% 990,161 $30.3M
State Street Corp. 0.00% Add +6.4% 873,432 $26.7M
Assenagon Asset Management S.A. 0.04% Add +4852.7% 839,934 $25.7M
Sanofi 9.67% No change 821,917 $25.2M
Palo Alto Investors LP 3.82% Reduce -17.1% 673,520 $20.6M
Soleus Capital Management, L.P. 1.02% Add +95.0% 626,040 $19.2M
683 Capital Management, LLC 1.59% Add +9.4% 547,000 $16.7M
Woodline Partners LP 0.07% No change 501,023 $15.3M
Geode Capital Management, LLC 0.00% Add +2.2% 473,626 $14.5M
Franklin Resources Inc. 0.00% Reduce -86.7% 47,332 $11.6M
Jacobs Levy Equity Management, Inc. 0.05% Add +2.7% 378,452 $11.6M
Two Sigma Advisers, LP 0.02% Add +28.7% 373,700 $11.4M
Arrowstreet Capital, Limited Partnership 0.01% Add +145.7% 370,458 $11.3M
D. E. Shaw & Co. 0.01% Add +211.0% 349,360 $10.7M
Nuveen, LLC 0.00% Add +4.9% 339,271 $10.4M
Goldman Sachs Group Inc. 0.00% Add +17.9% 329,820 $10.1M
T. Rowe Price Associates Inc. 0.00% Reduce -55.5% 299,311 $9.2M
Two Sigma Investments, LP 0.01% Add +10.8% 256,420 $7.9M
Sofinnova Investments, Inc. 0.48% Reduce -75.4% 254,268 $7.8M
Ensign Peak Advisors, Inc 0.01% No change 215,454 $6.6M
Charles Schwab Investment Management Inc. 0.00% Add +31.4% 206,441 $6.3M
Victory Capital Management Inc. 0.00% Reduce -61.6% 204,055 $6.2M
Northern Trust Corp. 0.00% Reduce -0.4% 195,563 $6.0M
Sectoral Asset Management Inc. 3.68% Add +131.8% 194,485 $6.0M
Federated Hermes, Inc. 0.01% Add +2236.6% 193,327 $5.9M
Jane Street Group, LLC 0.01% Add +305.5% 181,112 $5.5M
Granahan Investment Management, LLC 0.19% Add +12.2% 147,773 $4.5M
Skandinaviska Enskilda Banken AB (publ) 0.02% Add +333.1% 145,191 $4.4M
Susquehanna International Group, LLP 0.01% Reduce -23.6% 144,604 $4.4M
HighMark Wealth Management LLC 1.95% Reduce -7.2% 135,050 $4.4M
Bank of America Corp. 0.00% Reduce -88.2% 127,241 $3.9M
Renaissance Technologies 0.01% Reduce -53.1% 123,300 $3.8M
Trexquant Investment LP 0.04% Reduce -43.9% 111,778 $3.4M
BNP Paribas Financial Markets 0.00% Add +2756.5% 105,663 $3.2M
Macquarie Group Ltd. 0.00% No change 93,732 $2.9M
Algert Global LLC 0.04% New 83,767 $2.6M
Jump Financial, LLC 0.03% New 82,077 $2.5M
UBS Group AG 0.00% Reduce -94.1% 75,262 $2.3M
Citigroup Inc. 0.00% Reduce -93.3% 70,534 $2.2M
Squarepoint Ops LLC 0.00% Reduce -37.8% 68,014 $2.1M
Wellington Management Group LLP 0.00% Reduce -16.8% 66,731 $2.0M
Panagora Asset Management Inc. 0.01% Add +91.4% 63,857 $2.0M
Barclays PLC 0.00% Reduce -36.5% 63,452 $1.9M
Fisher Asset Management 0.00% Reduce -0.0% 58,878 $1.8M
Bank of New York Mellon Corp 0.00% Reduce -3.7% 57,030 $1.7M
Walleye Capital LLC 0.02% New 56,422 $1.7M
Marshall Wace, LLP 0.00% New 54,416 $1.7M
FMR LLC 0.00% Reduce -26.3% 53,162 $1.6M
Moody Aldrich Partners LLC 0.29% Reduce -17.0% 49,882 $1.5M
Ikarian Capital, LLC 0.30% Add +209.1% 48,410 $1.5M
DCF Advisers, LLC 0.56% No change 48,000 $1.5M
PDT Partners, LLC 0.08% Reduce -3.3% 43,001 $1.3M
Invesco Ltd. 0.00% Reduce -49.0% 42,381 $1.3M
Bleakley Financial Group, LLC 0.03% Add +6.5% 39,981 $1.2M
Gsa Capital Partners LLP 0.10% Reduce -46.6% 37,274 $1.1M
Susquehanna Portfolio Strategies, LLC 0.02% Add +8.1% 35,448 $1.1M
Russell Investments Group, Ltd. 0.00% Add +43.0% 34,032 $1.0M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% Reduce -33.2% 33,271 $1.0M
Aquatic Capital Management LLC 0.02% Reduce -52.4% 31,298 $958K
Alliancebernstein L.P. 0.00% No change 30,520 $935K
Rafferty Asset Management, LLC 0.00% Add +12.1% 30,085 $921K
Rhumbline Advisers 0.00% Reduce -4.8% 29,244 $895K
Engineers Gate Manager LP 0.01% Add +17.8% 29,137 $892K
Swiss National Bank 0.00% Add +7.6% 28,400 $870K
Boothbay Fund Management, LLC 0.02% New 27,402 $839K
ExodusPoint Capital Management, LP 0.01% Add +11.6% 26,500 $811K
Citadel Advisors 0.00% Reduce -77.6% 26,480 $811K
AQR Capital Management 0.00% Reduce -5.6% 26,174 $801K
Brevan Howard Capital Management LP 0.01% Add +10.2% 25,299 $775K
HRT Financial LP 0.00% New 25,025 $766K
Legal & General Group Plc 0.00% No change 19,504 $597K
Campbell & CO Investment Adviser LLC 0.04% New 18,281 $560K
XTX Topco Ltd 0.03% Reduce -40.9% 18,111 $555K
Creative Planning 0.00% Reduce -0.9% 16,707 $512K
Cresset Asset Management, LLC 0.00% Add +20.9% 15,753 $482K
Virtu Financial LLC 0.03% New 15,531 $476K
Graham Capital Management, L.P. 0.03% New 15,320 $469K
Sei Investments Co. 0.00% New 14,921 $457K
Los Angeles Capital Management LLC 0.00% Reduce -1.0% 14,876 $456K
JPMorgan Chase & Co. 0.00% Reduce -94.0% 14,852 $455K
California State Teachers Retirement System 0.00% Reduce -0.0% 14,215 $435K
Tudor Investment Corporation 0.00% Add +47.2% 13,869 $425K
Wells Fargo & Company 0.00% Reduce -58.8% 13,743 $421K
Orion Porfolio Solutions, LLC 0.00% New 13,739 $421K
Alps Advisors Inc. 0.00% Reduce -15.9% 13,335 $408K
Voya Investment Management LLC 0.00% Reduce -82.3% 12,961 $397K
Man Group plc 0.00% New 12,859 $394K
Deutsche Bank AG 0.00% No change 12,681 $388K
MetLife Investment Management, LLC 0.00% New 11,928 $365K
Tema ETFs LLC 0.03% Reduce -3.8% 10,975 $336K
NEOS Investment Management LLC 0.00% Reduce -3.8% 10,975 $336K
New York State Common Retirement Fund 0.00% Add +33.6% 10,586 $324K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% New 10,667 $315K
China Universal Asset Management Co., Ltd. 0.03% Add +67.9% 9,907 $303K
Voloridge Investment Management, LLC 0.00% New 9,321 $285K
AlphaQuest LLC 0.02% New 9,043 $277K
Intech Investment Management LLC 0.00% Reduce -27.7% 7,805 $239K
Janus Henderson Group PLC 0.00% New 7,464 $229K
DRW Securities, LLC 0.01% New 6,629 $209K
Manufacturers Life Insurance Company, The 0.00% New 6,719 $206K
Covestor Ltd 0.11% Add +131540.0% 6,582 $201K
Profund Advisors LLC 0.01% New 6,563 $201K
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% No change 6,498 $199K
Public Employees Retirement Association of Colorado 0.00% No change 4,864 $149K
Virtus Investment Advisers, LLC 0.04% Add +21.0% 4,860 $149K
Police & Firemen's Retirement System of New Jersey 0.00% Add +9.1% 4,559 $140K
Diadema Partners LP 0.07% New 3,295 $101K
KLP Kapitalforvaltning As 0.00% No change 3,000 $92K
Tower Research Capital LLC (TRC) 0.00% Reduce -10.3% 1,940 $59K
Ameritas Investment Partners, Inc. 0.00% No change 1,917 $59K
Osaic Holdings, Inc. 0.00% Reduce -22.6% 1,816 $56K
US Bancorp \de 0.00% Reduce -69.7% 1,790 $55K
Bessemer Group Inc. 0.00% Add +950.0% 1,428 $44K
Larson Financial Group LLC 0.00% Add +54.6% 1,340 $41K
Global Retirement Partners, LLC 0.00% No change 1,230 $38K
Mirae Asset Global Investments Co., Ltd. 0.00% Reduce -4.7% 1,082 $33K
Nisa Investment Advisors, LLC 0.00% No change 1,050 $32K
Cwm, LLC 0.00% Reduce -11.2% 1,009 $31K
EverSource Wealth Advisors, LLC 0.00% Reduce -10.8% 965 $30K
Persistent Asset Partners Ltd 0.02% New 754 $23K
Amalgamated Bank 0.00% No change 745 $23K
Allworth Financial LP 0.00% Reduce -0.9% 671 $21K
GF Fund Management Co. LTD. 0.00% Reduce -22.7% 602 $18K
CANADA LIFE ASSURANCE Co 0.00% No change 750 $17K
Versant Capital Management, Inc 0.00% Add +404.4% 454 $14K
Signaturefd, LLC 0.00% Reduce -22.3% 352 $11K
GAMMA Investing LLC 0.00% Reduce -3.3% 349 $11K
Farther Finance Advisors, LLC 0.00% Reduce -18.4% 275 $8K
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.00% Add +16.2% 272 $8K
Whittier Trust Co. 0.00% New 233 $7K
Quadrant Capital Group LLC 0.00% New 175 $5K
Summit Securities Group LLC 0.00% New 170 $5K
Rothschild Investment LLC 0.00% Reduce -10.8% 165 $5K
Royal Bank of Canada 0.00% Reduce -87.8% 158 $5K
Caitong International Asset Management Co., Ltd 0.00% New 147 $5K
PNC Financial Services Group, Inc. 0.00% Reduce -4.3% 110 $3K
Daiwa Securities Group Inc. 0.00% No change 105 $3K
Optiver Holding B.V. 0.00% New 90 $3K
Physician Wealth Advisors, Inc. 0.00% No change 85 $3K
Parallel Advisors, LLC 0.00% No change 55 $2K
Sterling Capital Management LLC 0.00% Reduce -6.0% 47 $1K
Steward Partners Investment Advisory, LLC 0.00% No change 43 $1K
Assetmark, Inc. 0.00% No change 36 $1K
Essential Partners LLC 0.00% No change 33 $1K
Parkside Financial Bank & Trust 0.00% No change 25 $766
Blue Trust, Inc. 0.00% No change 19 $582
Principal Securities, Inc. 0.00% No change 14 $429
MassMutual Private Wealth & Trust, FSB 0.00% No change 12 $367
Smartleaf Asset Management LLC 0.00% No change 14 $325
Montag A & Associates Inc. 0.00% New 9 $276
Stone House Investment Management, LLC 0.00% New 5 $153
True Wealth Design, LLC 0.00% No change 4 $123
Sunbelt Securities, Inc. 0.00% New 4 $122
SBI Securities Co., Ltd. 0.00% Add +300.0% 4 $122
Advisory Services Network, LLC 0.00% New 3 $92
CIBC Private Wealth Group LLC 0.00% New 1 $31
IFP Advisors, Inc 0.00% Add +0.0% 1 $31
TFC Financial Management, Inc. 0.00% New 1 $31
Cloud Capital Management, LLC 0.00% New 2 $0

"% of holder's portfolio" is ANAB's weight in each manager's 13F, not the share of Anaptysbio Inc. the manager owns.