AnaptysbioANAB
13F holders, Q3 2025 (September 30)At the end of Q3 2025, 166 institutions reported holding Anaptysbio Inc. (ANAB) in their 13F filings, up 19 from Q2 2025. 34 opened new positions and 14 sold out. The largest holders were EcoR1 Capital, LLC ($241.3M), Point72 Asset Management ($69.4M) and BlackRock, Inc. ($52.7M). 8 famous investors held it, including Steve Cohen (0.2% of Point72 Asset Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio).
- Company
- Anaptysbio Inc.
- CUSIP
- 032724106
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 34 | $15.1M |
| Exits | 14 | $5.8M |
All 13F filers, Q2 2025 → Q3 2025: 4,518,050 shares bought and 9,471,191 shares sold, net −4,953,141 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 166 holders
| EcoR1 Capital, LLC | 11.60% | No change | 7,880,094 | $241.3M |
| Point72 Asset Management | 0.16% | Reduce -8.5% | 2,265,528 | $69.4M |
| BlackRock, Inc. | 0.00% | Reduce -3.6% | 1,722,324 | $52.7M |
| Morgan Stanley | 0.00% | Reduce -16.8% | 1,556,258 | $47.7M |
| Millennium Management | 0.04% | Add +646.4% | 1,519,230 | $46.5M |
| Vanguard Group Inc. | 0.00% | Reduce -3.9% | 1,476,989 | $45.2M |
| Tang Capital Management LLC | 1.57% | Add +0.2% | 1,333,639 | $40.8M |
| First Light Asset Management, LLC | 2.86% | Reduce -72.0% | 990,161 | $30.3M |
| State Street Corp. | 0.00% | Add +6.4% | 873,432 | $26.7M |
| Assenagon Asset Management S.A. | 0.04% | Add +4852.7% | 839,934 | $25.7M |
| Sanofi | 9.67% | No change | 821,917 | $25.2M |
| Palo Alto Investors LP | 3.82% | Reduce -17.1% | 673,520 | $20.6M |
| Soleus Capital Management, L.P. | 1.02% | Add +95.0% | 626,040 | $19.2M |
| 683 Capital Management, LLC | 1.59% | Add +9.4% | 547,000 | $16.7M |
| Woodline Partners LP | 0.07% | No change | 501,023 | $15.3M |
| Geode Capital Management, LLC | 0.00% | Add +2.2% | 473,626 | $14.5M |
| Franklin Resources Inc. | 0.00% | Reduce -86.7% | 47,332 | $11.6M |
| Jacobs Levy Equity Management, Inc. | 0.05% | Add +2.7% | 378,452 | $11.6M |
| Two Sigma Advisers, LP | 0.02% | Add +28.7% | 373,700 | $11.4M |
| Arrowstreet Capital, Limited Partnership | 0.01% | Add +145.7% | 370,458 | $11.3M |
| D. E. Shaw & Co. | 0.01% | Add +211.0% | 349,360 | $10.7M |
| Nuveen, LLC | 0.00% | Add +4.9% | 339,271 | $10.4M |
| Goldman Sachs Group Inc. | 0.00% | Add +17.9% | 329,820 | $10.1M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -55.5% | 299,311 | $9.2M |
| Two Sigma Investments, LP | 0.01% | Add +10.8% | 256,420 | $7.9M |
| Sofinnova Investments, Inc. | 0.48% | Reduce -75.4% | 254,268 | $7.8M |
| Ensign Peak Advisors, Inc | 0.01% | No change | 215,454 | $6.6M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +31.4% | 206,441 | $6.3M |
| Victory Capital Management Inc. | 0.00% | Reduce -61.6% | 204,055 | $6.2M |
| Northern Trust Corp. | 0.00% | Reduce -0.4% | 195,563 | $6.0M |
| Sectoral Asset Management Inc. | 3.68% | Add +131.8% | 194,485 | $6.0M |
| Federated Hermes, Inc. | 0.01% | Add +2236.6% | 193,327 | $5.9M |
| Jane Street Group, LLC | 0.01% | Add +305.5% | 181,112 | $5.5M |
| Granahan Investment Management, LLC | 0.19% | Add +12.2% | 147,773 | $4.5M |
| Skandinaviska Enskilda Banken AB (publ) | 0.02% | Add +333.1% | 145,191 | $4.4M |
| Susquehanna International Group, LLP | 0.01% | Reduce -23.6% | 144,604 | $4.4M |
| HighMark Wealth Management LLC | 1.95% | Reduce -7.2% | 135,050 | $4.4M |
| Bank of America Corp. | 0.00% | Reduce -88.2% | 127,241 | $3.9M |
| Renaissance Technologies | 0.01% | Reduce -53.1% | 123,300 | $3.8M |
| Trexquant Investment LP | 0.04% | Reduce -43.9% | 111,778 | $3.4M |
| BNP Paribas Financial Markets | 0.00% | Add +2756.5% | 105,663 | $3.2M |
| Macquarie Group Ltd. | 0.00% | No change | 93,732 | $2.9M |
| Algert Global LLC | 0.04% | New | 83,767 | $2.6M |
| Jump Financial, LLC | 0.03% | New | 82,077 | $2.5M |
| UBS Group AG | 0.00% | Reduce -94.1% | 75,262 | $2.3M |
| Citigroup Inc. | 0.00% | Reduce -93.3% | 70,534 | $2.2M |
| Squarepoint Ops LLC | 0.00% | Reduce -37.8% | 68,014 | $2.1M |
| Wellington Management Group LLP | 0.00% | Reduce -16.8% | 66,731 | $2.0M |
| Panagora Asset Management Inc. | 0.01% | Add +91.4% | 63,857 | $2.0M |
| Barclays PLC | 0.00% | Reduce -36.5% | 63,452 | $1.9M |
| Fisher Asset Management | 0.00% | Reduce -0.0% | 58,878 | $1.8M |
| Bank of New York Mellon Corp | 0.00% | Reduce -3.7% | 57,030 | $1.7M |
| Walleye Capital LLC | 0.02% | New | 56,422 | $1.7M |
| Marshall Wace, LLP | 0.00% | New | 54,416 | $1.7M |
| FMR LLC | 0.00% | Reduce -26.3% | 53,162 | $1.6M |
| Moody Aldrich Partners LLC | 0.29% | Reduce -17.0% | 49,882 | $1.5M |
| Ikarian Capital, LLC | 0.30% | Add +209.1% | 48,410 | $1.5M |
| DCF Advisers, LLC | 0.56% | No change | 48,000 | $1.5M |
| PDT Partners, LLC | 0.08% | Reduce -3.3% | 43,001 | $1.3M |
| Invesco Ltd. | 0.00% | Reduce -49.0% | 42,381 | $1.3M |
| Bleakley Financial Group, LLC | 0.03% | Add +6.5% | 39,981 | $1.2M |
| Gsa Capital Partners LLP | 0.10% | Reduce -46.6% | 37,274 | $1.1M |
| Susquehanna Portfolio Strategies, LLC | 0.02% | Add +8.1% | 35,448 | $1.1M |
| Russell Investments Group, Ltd. | 0.00% | Add +43.0% | 34,032 | $1.0M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -33.2% | 33,271 | $1.0M |
| Aquatic Capital Management LLC | 0.02% | Reduce -52.4% | 31,298 | $958K |
| Alliancebernstein L.P. | 0.00% | No change | 30,520 | $935K |
| Rafferty Asset Management, LLC | 0.00% | Add +12.1% | 30,085 | $921K |
| Rhumbline Advisers | 0.00% | Reduce -4.8% | 29,244 | $895K |
| Engineers Gate Manager LP | 0.01% | Add +17.8% | 29,137 | $892K |
| Swiss National Bank | 0.00% | Add +7.6% | 28,400 | $870K |
| Boothbay Fund Management, LLC | 0.02% | New | 27,402 | $839K |
| ExodusPoint Capital Management, LP | 0.01% | Add +11.6% | 26,500 | $811K |
| Citadel Advisors | 0.00% | Reduce -77.6% | 26,480 | $811K |
| AQR Capital Management | 0.00% | Reduce -5.6% | 26,174 | $801K |
| Brevan Howard Capital Management LP | 0.01% | Add +10.2% | 25,299 | $775K |
| HRT Financial LP | 0.00% | New | 25,025 | $766K |
| Legal & General Group Plc | 0.00% | No change | 19,504 | $597K |
| Campbell & CO Investment Adviser LLC | 0.04% | New | 18,281 | $560K |
| XTX Topco Ltd | 0.03% | Reduce -40.9% | 18,111 | $555K |
| Creative Planning | 0.00% | Reduce -0.9% | 16,707 | $512K |
| Cresset Asset Management, LLC | 0.00% | Add +20.9% | 15,753 | $482K |
| Virtu Financial LLC | 0.03% | New | 15,531 | $476K |
| Graham Capital Management, L.P. | 0.03% | New | 15,320 | $469K |
| Sei Investments Co. | 0.00% | New | 14,921 | $457K |
| Los Angeles Capital Management LLC | 0.00% | Reduce -1.0% | 14,876 | $456K |
| JPMorgan Chase & Co. | 0.00% | Reduce -94.0% | 14,852 | $455K |
| California State Teachers Retirement System | 0.00% | Reduce -0.0% | 14,215 | $435K |
| Tudor Investment Corporation | 0.00% | Add +47.2% | 13,869 | $425K |
| Wells Fargo & Company | 0.00% | Reduce -58.8% | 13,743 | $421K |
| Orion Porfolio Solutions, LLC | 0.00% | New | 13,739 | $421K |
| Alps Advisors Inc. | 0.00% | Reduce -15.9% | 13,335 | $408K |
| Voya Investment Management LLC | 0.00% | Reduce -82.3% | 12,961 | $397K |
| Man Group plc | 0.00% | New | 12,859 | $394K |
| Deutsche Bank AG | 0.00% | No change | 12,681 | $388K |
| MetLife Investment Management, LLC | 0.00% | New | 11,928 | $365K |
| Tema ETFs LLC | 0.03% | Reduce -3.8% | 10,975 | $336K |
| NEOS Investment Management LLC | 0.00% | Reduce -3.8% | 10,975 | $336K |
| New York State Common Retirement Fund | 0.00% | Add +33.6% | 10,586 | $324K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | New | 10,667 | $315K |
| China Universal Asset Management Co., Ltd. | 0.03% | Add +67.9% | 9,907 | $303K |
| Voloridge Investment Management, LLC | 0.00% | New | 9,321 | $285K |
| AlphaQuest LLC | 0.02% | New | 9,043 | $277K |
| Intech Investment Management LLC | 0.00% | Reduce -27.7% | 7,805 | $239K |
| Janus Henderson Group PLC | 0.00% | New | 7,464 | $229K |
| DRW Securities, LLC | 0.01% | New | 6,629 | $209K |
| Manufacturers Life Insurance Company, The | 0.00% | New | 6,719 | $206K |
| Covestor Ltd | 0.11% | Add +131540.0% | 6,582 | $201K |
| Profund Advisors LLC | 0.01% | New | 6,563 | $201K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | No change | 6,498 | $199K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 4,864 | $149K |
| Virtus Investment Advisers, LLC | 0.04% | Add +21.0% | 4,860 | $149K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +9.1% | 4,559 | $140K |
| Diadema Partners LP | 0.07% | New | 3,295 | $101K |
| KLP Kapitalforvaltning As | 0.00% | No change | 3,000 | $92K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -10.3% | 1,940 | $59K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 1,917 | $59K |
| Osaic Holdings, Inc. | 0.00% | Reduce -22.6% | 1,816 | $56K |
| US Bancorp \de | 0.00% | Reduce -69.7% | 1,790 | $55K |
| Bessemer Group Inc. | 0.00% | Add +950.0% | 1,428 | $44K |
| Larson Financial Group LLC | 0.00% | Add +54.6% | 1,340 | $41K |
| Global Retirement Partners, LLC | 0.00% | No change | 1,230 | $38K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Reduce -4.7% | 1,082 | $33K |
| Nisa Investment Advisors, LLC | 0.00% | No change | 1,050 | $32K |
| Cwm, LLC | 0.00% | Reduce -11.2% | 1,009 | $31K |
| EverSource Wealth Advisors, LLC | 0.00% | Reduce -10.8% | 965 | $30K |
| Persistent Asset Partners Ltd | 0.02% | New | 754 | $23K |
| Amalgamated Bank | 0.00% | No change | 745 | $23K |
| Allworth Financial LP | 0.00% | Reduce -0.9% | 671 | $21K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -22.7% | 602 | $18K |
| CANADA LIFE ASSURANCE Co | 0.00% | No change | 750 | $17K |
| Versant Capital Management, Inc | 0.00% | Add +404.4% | 454 | $14K |
| Signaturefd, LLC | 0.00% | Reduce -22.3% | 352 | $11K |
| GAMMA Investing LLC | 0.00% | Reduce -3.3% | 349 | $11K |
| Farther Finance Advisors, LLC | 0.00% | Reduce -18.4% | 275 | $8K |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | Add +16.2% | 272 | $8K |
| Whittier Trust Co. | 0.00% | New | 233 | $7K |
| Quadrant Capital Group LLC | 0.00% | New | 175 | $5K |
| Summit Securities Group LLC | 0.00% | New | 170 | $5K |
| Rothschild Investment LLC | 0.00% | Reduce -10.8% | 165 | $5K |
| Royal Bank of Canada | 0.00% | Reduce -87.8% | 158 | $5K |
| Caitong International Asset Management Co., Ltd | 0.00% | New | 147 | $5K |
| PNC Financial Services Group, Inc. | 0.00% | Reduce -4.3% | 110 | $3K |
| Daiwa Securities Group Inc. | 0.00% | No change | 105 | $3K |
| Optiver Holding B.V. | 0.00% | New | 90 | $3K |
| Physician Wealth Advisors, Inc. | 0.00% | No change | 85 | $3K |
| Parallel Advisors, LLC | 0.00% | No change | 55 | $2K |
| Sterling Capital Management LLC | 0.00% | Reduce -6.0% | 47 | $1K |
| Steward Partners Investment Advisory, LLC | 0.00% | No change | 43 | $1K |
| Assetmark, Inc. | 0.00% | No change | 36 | $1K |
| Essential Partners LLC | 0.00% | No change | 33 | $1K |
| Parkside Financial Bank & Trust | 0.00% | No change | 25 | $766 |
| Blue Trust, Inc. | 0.00% | No change | 19 | $582 |
| Principal Securities, Inc. | 0.00% | No change | 14 | $429 |
| MassMutual Private Wealth & Trust, FSB | 0.00% | No change | 12 | $367 |
| Smartleaf Asset Management LLC | 0.00% | No change | 14 | $325 |
| Montag A & Associates Inc. | 0.00% | New | 9 | $276 |
| Stone House Investment Management, LLC | 0.00% | New | 5 | $153 |
| True Wealth Design, LLC | 0.00% | No change | 4 | $123 |
| Sunbelt Securities, Inc. | 0.00% | New | 4 | $122 |
| SBI Securities Co., Ltd. | 0.00% | Add +300.0% | 4 | $122 |
| Advisory Services Network, LLC | 0.00% | New | 3 | $92 |
| CIBC Private Wealth Group LLC | 0.00% | New | 1 | $31 |
| IFP Advisors, Inc | 0.00% | Add +0.0% | 1 | $31 |
| TFC Financial Management, Inc. | 0.00% | New | 1 | $31 |
| Cloud Capital Management, LLC | 0.00% | New | 2 | $0 |
"% of holder's portfolio" is ANAB's weight in each manager's 13F, not the share of Anaptysbio Inc. the manager owns.