Apogee TherapeuticsAPGE
13F holders, Q3 2025 (September 30)174holders −8
24new positions
32sold out
3famous investors
$39.74avg. 13F price*
At the end of Q3 2025, 174 institutions reported holding Apogee Therapeutics Inc. (APGE) in their 13F filings, down 8 from Q2 2025. 24 opened new positions and 32 sold out. The largest holders were Venrock Adviser, LLC ($337.4M), FMR LLC ($274.8M) and Wellington Management Group LLP ($187.7M). 3 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio).
- Company
- Apogee Therapeutics Inc.
- CUSIP
- 03770N101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 24 | $72.2M |
| Exits | 32 | $130.1M |
All 13F filers, Q2 2025 → Q3 2025: 7,909,337 shares bought and 6,176,727 shares sold, net +1,732,610 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 174 holders
| Venrock Adviser, LLC | 18.99% | No change | 8,493,321 | $337.4M |
| FMR LLC | 0.01% | Add +0.1% | 6,916,462 | $274.8M |
| Wellington Management Group LLP | 0.03% | Add +24.1% | 4,723,701 | $187.7M |
| RTW Investments, LP | 1.33% | No change | 2,712,097 | $107.8M |
| BlackRock, Inc. | 0.00% | Add +4.8% | 2,686,026 | $106.7M |
| Vanguard Group Inc. | 0.00% | Add +6.5% | 2,245,631 | $89.2M |
| Driehaus Capital Management LLC | 0.61% | Reduce -6.6% | 2,158,502 | $85.8M |
| Fairmount Funds Management LLC | 7.32% | No change | 2,048,647 | $81.4M |
| State Street Corp. | 0.00% | Add +31.5% | 1,655,548 | $65.8M |
| Paradigm Biocapital Advisors LP | 1.79% | Add +58.7% | 1,521,757 | $60.5M |
| Braidwell LP | 2.31% | Reduce -2.7% | 1,438,745 | $57.2M |
| Alliancebernstein L.P. | 0.02% | Add +2.2% | 1,419,132 | $56.4M |
| Perceptive Advisors LLC | 1.58% | Add +14.4% | 1,351,989 | $53.7M |
| Affinity Asset Advisors, LLC | 4.48% | Add +69.6% | 1,173,426 | $46.6M |
| Citadel Advisors | 0.04% | Add +135.9% | 1,169,244 | $46.5M |
| JPMorgan Chase & Co. | 0.00% | Add +1.1% | 1,137,731 | $45.2M |
| Mercer Global Advisors Inc. | 0.06% | Add +18.3% | 970,581 | $38.6M |
| Geode Capital Management, LLC | 0.00% | Add +14.0% | 892,203 | $35.5M |
| UBS Group AG | 0.01% | Add +646.1% | 799,465 | $31.8M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -1.4% | 750,529 | $29.8M |
| Franklin Resources Inc. | 0.01% | Reduce -14.3% | 730,761 | $29.0M |
| Barclays PLC | 0.01% | Add +5.5% | 642,316 | $25.5M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -9.0% | 599,616 | $23.8M |
| Jefferies Financial Group Inc. | 0.21% | Reduce -11.6% | 568,084 | $22.6M |
| Sofinnova Investments, Inc. | 1.38% | Add +642.2% | 565,417 | $22.5M |
| Polar Capital Holdings Plc | 0.10% | Add +5.9% | 524,094 | $20.8M |
| Novo Holdings A/S | 1.28% | Add +11.3% | 500,000 | $19.9M |
| Janus Henderson Group PLC | 0.01% | Reduce -4.6% | 485,978 | $19.3M |
| Morgan Stanley | 0.00% | Reduce -2.0% | 464,963 | $18.5M |
| Millennium Management | 0.01% | Add +75.6% | 430,463 | $17.1M |
| Vestal Point Capital, LP | 0.77% | New | 425,000 | $16.9M |
| First Turn Management, LLC | 2.40% | Add +29.3% | 402,811 | $16.0M |
| Bank of America Corp. | 0.00% | Reduce -22.6% | 393,912 | $15.7M |
| Frontier Capital Management Co. LLC | 0.13% | Add +21.1% | 374,407 | $14.9M |
| Opaleye Management Inc. | 2.05% | New | 363,257 | $14.4M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +20.1% | 319,903 | $12.7M |
| Great Point Partners LLC | 5.04% | New | 304,000 | $12.1M |
| Commodore Capital LP | 0.56% | No change | 290,000 | $11.5M |
| Northern Trust Corp. | 0.00% | Add +7.7% | 284,483 | $11.3M |
| Adage Capital Partners Gp, L.L.C. | 0.01% | Reduce -81.8% | 235,000 | $9.3M |
| Victory Capital Management Inc. | 0.01% | Reduce -14.7% | 217,213 | $8.6M |
| Schroder Investment Management Group | 0.01% | Add +81.0% | 215,846 | $8.6M |
| Tang Capital Management LLC | 0.31% | No change | 200,000 | $7.9M |
| Blackstone Inc. | 0.03% | Add +6.6% | 190,352 | $7.6M |
| SG Americas Securities, LLC | 0.02% | New | 134,226 | $5.3M |
| Granahan Investment Management, LLC | 0.22% | Add +1.0% | 132,400 | $5.3M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.01% | Add +4.5% | 131,436 | $5.2M |
| Capital World Investors | 0.00% | Reduce -34.2% | 127,618 | $5.1M |
| Candriam S.C.A. | 0.03% | New | 126,081 | $5.0M |
| Kennedy Capital Management LLC | 0.11% | Add +63.5% | 124,051 | $4.9M |
| Two Sigma Investments, LP | 0.01% | Add +5.8% | 122,375 | $4.9M |
| ArrowMark Colorado Holdings LLC | 0.08% | No change | 109,410 | $4.3M |
| Bank of New York Mellon Corp | 0.00% | Reduce -46.5% | 107,540 | $4.3M |
| HighVista Strategies LLC | 1.04% | Add +137.7% | 107,107 | $4.3M |
| Parkman Healthcare Partners LLC | 0.46% | Add +91.0% | 105,831 | $4.2M |
| Ameriprise Financial Inc. | 0.00% | Reduce -33.9% | 103,152 | $4.1M |
| D. E. Shaw & Co. | 0.00% | Reduce -48.3% | 100,570 | $4.0M |
| Exome Asset Management LLC | 2.48% | New | 94,400 | $3.8M |
| Platinum Investment Management Ltd. | 0.24% | Add +8.3% | 93,728 | $3.7M |
| Nuveen, LLC | 0.00% | No change | 83,291 | $3.3M |
| TD Asset Management Inc | 0.00% | Reduce -12.0% | 83,240 | $3.3M |
| Jane Street Group, LLC | 0.00% | Add +842.6% | 77,626 | $3.1M |
| Deutsche Bank AG | 0.00% | Add +222.9% | 76,547 | $3.0M |
| Balyasny Asset Management L.P. | 0.01% | Reduce -54.4% | 72,348 | $2.9M |
| Rafferty Asset Management, LLC | 0.01% | Add +55.9% | 65,796 | $2.6M |
| Diadema Partners LP | 1.78% | Add +507.7% | 64,250 | $2.6M |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -13.3% | 63,225 | $2.5M |
| J. Goldman & Co LP | 0.09% | Add +80.8% | 62,577 | $2.5M |
| Exane Asset Management | 0.81% | New | 51,543 | $2.4M |
| Woodline Partners LP | 0.01% | Reduce -93.4% | 57,321 | $2.3M |
| Aberdeen Group plc | 0.00% | New | 54,760 | $2.2M |
| Boxer Capital Management, LLC | 0.63% | New | 50,000 | $2.0M |
| Verition Fund Management LLC | 0.01% | New | 49,523 | $2.0M |
| Rhumbline Advisers | 0.00% | Reduce -2.9% | 47,799 | $1.9M |
| Russell Investments Group, Ltd. | 0.00% | Add +100.6% | 43,673 | $1.7M |
| Swiss National Bank | 0.00% | Add +1.9% | 43,400 | $1.7M |
| Aquatic Capital Management LLC | 0.03% | New | 39,332 | $1.6M |
| BNP Paribas Financial Markets | 0.00% | Add +947.5% | 38,223 | $1.5M |
| ExodusPoint Capital Management, LP | 0.02% | New | 37,535 | $1.5M |
| Comerica Bank | 0.01% | Add +20.6% | 35,534 | $1.4M |
| B Group, Inc. | 1.39% | No change | 35,000 | $1.4M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -43.4% | 31,163 | $1.2M |
| Invesco Ltd. | 0.00% | Add +8.5% | 29,138 | $1.2M |
| Legal & General Group Plc | 0.00% | Reduce -0.1% | 27,663 | $1.1M |
| SummitTX Capital, L.P. | 0.04% | New | 26,607 | $1.1M |
| Prelude Capital Management, LLC | 0.08% | New | 26,241 | $1.0M |
| AXA Investment Managers S.A. | 0.00% | — | 24,554 | $976K |
| Erste Asset Management GmbH | 0.01% | No change | 24,000 | $956K |
| Alps Advisors Inc. | 0.01% | Reduce -9.4% | 22,506 | $894K |
| Wells Fargo & Company | 0.00% | Add +30.5% | 21,990 | $874K |
| California State Teachers Retirement System | 0.00% | Add +0.0% | 21,387 | $850K |
| MetLife Investment Management, LLC | 0.00% | No change | 19,238 | $764K |
| LMR Partners LLP | 0.01% | New | 18,961 | $753K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -5.0% | 18,579 | $738K |
| Moody Aldrich Partners LLC | 0.14% | Reduce -16.7% | 18,012 | $716K |
| Susquehanna International Group, LLP | 0.00% | Reduce -56.9% | 16,689 | $663K |
| Birchview Capital, LP | 0.48% | No change | 16,000 | $636K |
| Persistent Asset Partners Ltd | 0.43% | Add +511.1% | 14,819 | $589K |
| Profund Advisors LLC | 0.02% | Add +57.8% | 14,171 | $563K |
| Intech Investment Management LLC | 0.00% | Reduce -14.7% | 13,701 | $544K |
"% of holder's portfolio" is APGE's weight in each manager's 13F, not the share of Apogee Therapeutics Inc. the manager owns.