Apogee TherapeuticsAPGE
13F holders, Q4 2025 (December 31)207holders +33
45new positions
18sold out
4famous investors
$75.48avg. 13F price*
At the end of Q4 2025, 207 institutions reported holding Apogee Therapeutics Inc. (APGE) in their 13F filings, up 33 from Q3 2025. 45 opened new positions and 18 sold out. The largest holders were Venrock Adviser, LLC ($641.1M), FMR LLC ($620.8M) and Wellington Management Group LLP ($358.3M). 4 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio), Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Apogee Therapeutics Inc.
- CUSIP
- 03770N101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 45 | $247.9M |
| Exits | 18 | $56.2M |
All 13F filers, Q3 2025 → Q4 2025: 14,951,559 shares bought and 5,545,361 shares sold, net +9,406,198 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 207 holders
| Venrock Adviser, LLC | 31.67% | No change | 8,493,321 | $641.1M |
| FMR LLC | 0.03% | Add +18.9% | 8,225,038 | $620.8M |
| Wellington Management Group LLP | 0.06% | Add +0.5% | 4,746,585 | $358.3M |
| BlackRock, Inc. | 0.00% | Add +40.9% | 3,783,994 | $285.6M |
| Vanguard Group Inc. | 0.00% | Add +27.3% | 2,857,824 | $215.7M |
| T. Rowe Price Investment Management, Inc. | 0.13% | Add +189522.2% | 2,732,456 | $206.2M |
| RTW Investments, LP | 2.05% | No change | 2,712,097 | $204.7M |
| Perceptive Advisors LLC | 3.23% | Add +72.4% | 2,330,651 | $175.9M |
| Driehaus Capital Management LLC | 1.12% | Add +1.2% | 2,183,704 | $164.8M |
| Janus Henderson Group PLC | 0.07% | Add +324.4% | 2,062,604 | $155.7M |
| Fairmount Funds Management LLC | 11.77% | No change | 2,048,647 | $154.6M |
| State Street Corp. | 0.00% | Add +2.1% | 1,690,186 | $127.6M |
| JPMorgan Chase & Co. | 0.01% | Add +20.7% | 1,373,066 | $103.6M |
| T. Rowe Price Associates Inc. | 0.01% | Add +64.8% | 1,237,135 | $93.4M |
| Affinity Asset Advisors, LLC | 6.91% | Add +5.2% | 1,234,926 | $93.2M |
| Paradigm Biocapital Advisors LP | 2.27% | Reduce -26.2% | 1,123,243 | $84.8M |
| Alliancebernstein L.P. | 0.03% | Reduce -22.9% | 1,093,657 | $82.5M |
| Geode Capital Management, LLC | 0.00% | Add +18.7% | 1,059,085 | $80.0M |
| UBS Group AG | 0.01% | Add +21.9% | 974,826 | $73.6M |
| Mercer Global Advisors Inc. | 0.10% | Reduce -8.2% | 890,665 | $67.2M |
| Morgan Stanley | 0.00% | Add +91.5% | 890,264 | $67.2M |
| Bank of America Corp. | 0.00% | Add +101.5% | 793,695 | $59.9M |
| Citadel Advisors | 0.04% | Reduce -34.4% | 766,981 | $57.9M |
| Remedium Capital Partners, LLC | 25.88% | — | 583,591 | $44.0M |
| Jennison Associates LLC | 0.03% | New | 578,627 | $43.7M |
| Braidwell LP | 1.66% | Reduce -60.0% | 575,067 | $43.4M |
| Novo Holdings A/S | 3.34% | Add +14.0% | 570,000 | $43.0M |
| Goldman Sachs Group Inc. | 0.01% | Reduce -5.7% | 565,410 | $42.7M |
| Vestal Point Capital, LP | 1.52% | Add +29.4% | 550,000 | $41.5M |
| Sofinnova Investments, Inc. | 1.74% | Reduce -5.4% | 534,845 | $40.4M |
| Polar Capital Holdings Plc | 0.17% | Reduce -3.9% | 503,539 | $38.0M |
| Avoro Capital Advisors LLC | 0.37% | New | 500,000 | $37.7M |
| Frontier Capital Management Co. LLC | 0.38% | Add +28.3% | 480,453 | $36.3M |
| First Turn Management, LLC | 4.10% | Add +17.9% | 474,839 | $35.8M |
| Franklin Resources Inc. | 0.01% | Reduce -38.3% | 451,002 | $34.0M |
| Eventide Asset Management, LLC | 0.51% | New | 436,015 | $32.9M |
| Opaleye Management Inc. | 3.87% | Add +6.9% | 388,257 | $29.3M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +19.2% | 381,362 | $28.8M |
| Great Point Partners LLC | 9.15% | Add +23.0% | 374,000 | $28.2M |
| Northern Trust Corp. | 0.00% | Add +15.1% | 327,376 | $24.7M |
| Pictet Asset Management Holding SA | 0.02% | New | 312,883 | $23.6M |
| First Light Asset Management, LLC | 1.64% | New | 284,991 | $21.5M |
| Loomis Sayles & Co. L P | 0.02% | New | 255,439 | $19.3M |
| Adage Capital Partners Gp, L.L.C. | 0.03% | Add +2.1% | 240,000 | $18.1M |
| Woodline Partners LP | 0.06% | Add +267.2% | 210,466 | $15.9M |
| Trails Edge Capital Partners, LP | 3.58% | — | 192,000 | $14.5M |
| Candriam S.C.A. | 0.07% | Add +51.7% | 191,318 | $14.4M |
| Millennium Management | 0.01% | Reduce -67.3% | 140,727 | $10.6M |
| Barclays PLC | 0.00% | Reduce -79.3% | 133,193 | $10.1M |
| Parkman Healthcare Partners LLC | 0.93% | Add +22.9% | 130,069 | $9.8M |
| TD Asset Management Inc | 0.01% | Add +55.3% | 129,290 | $9.8M |
| Federated Hermes, Inc. | 0.02% | New | 127,931 | $9.7M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.02% | Reduce -2.9% | 127,629 | $9.6M |
| Capital World Investors | 0.00% | No change | 127,618 | $9.6M |
| Kennedy Capital Management LLC | 0.20% | Add +0.8% | 124,979 | $9.4M |
| Ameriprise Financial Inc. | 0.00% | Add +19.1% | 122,900 | $9.3M |
| Nuveen, LLC | 0.00% | Add +45.3% | 121,050 | $9.1M |
| Bank of New York Mellon Corp | 0.00% | Add +9.8% | 118,084 | $8.9M |
| Nicholas Investment Partners, LP | 0.71% | New | 112,924 | $8.5M |
| ArrowMark Colorado Holdings LLC | 0.18% | No change | 109,410 | $8.3M |
| Victory Capital Management Inc. | 0.00% | Reduce -50.2% | 108,267 | $8.2M |
| Schroder Investment Management Group | 0.01% | Reduce -51.4% | 105,000 | $8.0M |
| Two Sigma Investments, LP | 0.01% | Reduce -14.0% | 105,241 | $7.9M |
| Neuberger Berman Group LLC | 0.01% | New | 99,648 | $7.5M |
| Granahan Investment Management, LLC | 0.31% | Reduce -28.5% | 94,720 | $7.1M |
| HighVista Strategies LLC | 1.73% | Reduce -16.7% | 89,229 | $6.7M |
| Manufacturers Life Insurance Company, The | 0.01% | Add +27.9% | 80,832 | $6.1M |
| Stempoint Capital LP | 1.04% | New | 80,574 | $6.1M |
| Deutsche Bank AG | 0.00% | Add +3.7% | 79,361 | $6.0M |
| Nomura Holdings Inc. | 0.02% | New | 76,898 | $5.8M |
| SG Americas Securities, LLC | 0.01% | Reduce -45.4% | 73,262 | $5.5M |
| Invesco Ltd. | 0.00% | Add +142.6% | 70,687 | $5.3M |
| Boxer Capital Management, LLC | 1.16% | Add +40.0% | 70,000 | $5.3M |
| Platinum Investment Management Ltd. | 1.21% | Reduce -26.2% | 69,212 | $5.2M |
| D. E. Shaw & Co. | 0.00% | Reduce -37.1% | 63,250 | $4.8M |
| Swiss National Bank | 0.00% | Add +44.9% | 62,900 | $4.7M |
| Simplex Trading, LLC | 0.13% | New | 62,799 | $4.7M |
| Prudential Financial Inc. | 0.00% | Add +322.2% | 54,300 | $4.1M |
| Blackstone Inc. | 0.02% | Reduce -72.8% | 51,827 | $3.9M |
| Marshall Wace, LLP | 0.00% | Add +622.1% | 50,744 | $3.8M |
| Seven Grand Managers, LLC | 0.29% | New | 50,000 | $3.8M |
| Russell Investments Group, Ltd. | 0.00% | Add +14.5% | 49,999 | $3.8M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +59.8% | 49,805 | $3.8M |
| Rafferty Asset Management, LLC | 0.01% | Reduce -26.1% | 48,619 | $3.7M |
| Rhumbline Advisers | 0.00% | Reduce -3.8% | 45,971 | $3.5M |
| Alps Advisors Inc. | 0.02% | Add +99.6% | 44,922 | $3.4M |
| Wells Fargo & Company | 0.00% | Add +93.3% | 42,499 | $3.2M |
| Banque Pictet & Cie SA | 0.03% | New | 41,800 | $3.2M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | Add +19625.7% | 39,846 | $3.0M |
| Aberdeen Group plc | 0.00% | Reduce -34.1% | 36,103 | $2.7M |
| Comerica Bank | 0.01% | Add +0.9% | 35,872 | $2.7M |
| Cinctive Capital Management LP | 0.14% | New | 33,264 | $2.5M |
| Legal & General Group Plc | 0.00% | Add +18.8% | 32,856 | $2.5M |
| California State Teachers Retirement System | 0.00% | Add +43.8% | 30,758 | $2.3M |
| Tudor Investment Corporation | 0.01% | New | 30,039 | $2.3M |
| Schonfeld Strategic Advisors LLC | 0.01% | New | 29,145 | $2.2M |
| Erste Asset Management GmbH | 0.02% | No change | 24,000 | $1.8M |
| New York State Common Retirement Fund | 0.00% | Add +127.4% | 22,484 | $1.7M |
| MetLife Investment Management, LLC | 0.01% | Add +10.8% | 21,311 | $1.6M |
| SummitTX Capital, L.P. | 0.05% | Reduce -21.2% | 20,972 | $1.6M |
"% of holder's portfolio" is APGE's weight in each manager's 13F, not the share of Apogee Therapeutics Inc. the manager owns.