Apogee TherapeuticsAPGE
13F holders, Q4 2025 (December 31)207holders +33
45new positions
18sold out
4famous investors
$75.48avg. 13F price*
At the end of Q4 2025, 207 institutions reported holding Apogee Therapeutics Inc. (APGE) in their 13F filings, up 33 from Q3 2025. 45 opened new positions and 18 sold out. The largest holders were Venrock Adviser, LLC ($641.1M), FMR LLC ($620.8M) and Wellington Management Group LLP ($358.3M). 4 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio), Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Apogee Therapeutics Inc.
- CUSIP
- 03770N101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 45 | $247.9M |
| Exits | 18 | $56.2M |
All 13F filers, Q3 2025 → Q4 2025: 14,951,559 shares bought and 5,545,361 shares sold, net +9,406,198 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 207 holders
| Venrock Adviser, LLC | 31.67% | No change | 8,493,321 | $641.1M |
| FMR LLC | 0.03% | Add +18.9% | 8,225,038 | $620.8M |
| Wellington Management Group LLP | 0.06% | Add +0.5% | 4,746,585 | $358.3M |
| BlackRock, Inc. | 0.00% | Add +40.9% | 3,783,994 | $285.6M |
| Vanguard Group Inc. | 0.00% | Add +27.3% | 2,857,824 | $215.7M |
| T. Rowe Price Investment Management, Inc. | 0.13% | Add +189522.2% | 2,732,456 | $206.2M |
| RTW Investments, LP | 2.05% | No change | 2,712,097 | $204.7M |
| Perceptive Advisors LLC | 3.23% | Add +72.4% | 2,330,651 | $175.9M |
| Driehaus Capital Management LLC | 1.12% | Add +1.2% | 2,183,704 | $164.8M |
| Janus Henderson Group PLC | 0.07% | Add +324.4% | 2,062,604 | $155.7M |
| Fairmount Funds Management LLC | 11.77% | No change | 2,048,647 | $154.6M |
| State Street Corp. | 0.00% | Add +2.1% | 1,690,186 | $127.6M |
| JPMorgan Chase & Co. | 0.01% | Add +20.7% | 1,373,066 | $103.6M |
| T. Rowe Price Associates Inc. | 0.01% | Add +64.8% | 1,237,135 | $93.4M |
| Affinity Asset Advisors, LLC | 6.91% | Add +5.2% | 1,234,926 | $93.2M |
| Paradigm Biocapital Advisors LP | 2.27% | Reduce -26.2% | 1,123,243 | $84.8M |
| Alliancebernstein L.P. | 0.03% | Reduce -22.9% | 1,093,657 | $82.5M |
| Geode Capital Management, LLC | 0.00% | Add +18.7% | 1,059,085 | $80.0M |
| UBS Group AG | 0.01% | Add +21.9% | 974,826 | $73.6M |
| Mercer Global Advisors Inc. | 0.10% | Reduce -8.2% | 890,665 | $67.2M |
| Morgan Stanley | 0.00% | Add +91.5% | 890,264 | $67.2M |
| Bank of America Corp. | 0.00% | Add +101.5% | 793,695 | $59.9M |
| Citadel Advisors | 0.04% | Reduce -34.4% | 766,981 | $57.9M |
| Remedium Capital Partners, LLC | 25.88% | — | 583,591 | $44.0M |
| Jennison Associates LLC | 0.03% | New | 578,627 | $43.7M |
| Braidwell LP | 1.66% | Reduce -60.0% | 575,067 | $43.4M |
| Novo Holdings A/S | 3.34% | Add +14.0% | 570,000 | $43.0M |
| Goldman Sachs Group Inc. | 0.01% | Reduce -5.7% | 565,410 | $42.7M |
| Vestal Point Capital, LP | 1.52% | Add +29.4% | 550,000 | $41.5M |
| Sofinnova Investments, Inc. | 1.74% | Reduce -5.4% | 534,845 | $40.4M |
| Polar Capital Holdings Plc | 0.17% | Reduce -3.9% | 503,539 | $38.0M |
| Avoro Capital Advisors LLC | 0.37% | New | 500,000 | $37.7M |
| Frontier Capital Management Co. LLC | 0.38% | Add +28.3% | 480,453 | $36.3M |
| First Turn Management, LLC | 4.10% | Add +17.9% | 474,839 | $35.8M |
| Franklin Resources Inc. | 0.01% | Reduce -38.3% | 451,002 | $34.0M |
| Eventide Asset Management, LLC | 0.51% | New | 436,015 | $32.9M |
| Opaleye Management Inc. | 3.87% | Add +6.9% | 388,257 | $29.3M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +19.2% | 381,362 | $28.8M |
| Great Point Partners LLC | 9.15% | Add +23.0% | 374,000 | $28.2M |
| Northern Trust Corp. | 0.00% | Add +15.1% | 327,376 | $24.7M |
| Pictet Asset Management Holding SA | 0.02% | New | 312,883 | $23.6M |
| First Light Asset Management, LLC | 1.64% | New | 284,991 | $21.5M |
| Loomis Sayles & Co. L P | 0.02% | New | 255,439 | $19.3M |
| Adage Capital Partners Gp, L.L.C. | 0.03% | Add +2.1% | 240,000 | $18.1M |
| Woodline Partners LP | 0.06% | Add +267.2% | 210,466 | $15.9M |
| Trails Edge Capital Partners, LP | 3.58% | — | 192,000 | $14.5M |
| Candriam S.C.A. | 0.07% | Add +51.7% | 191,318 | $14.4M |
| Millennium Management | 0.01% | Reduce -67.3% | 140,727 | $10.6M |
| Barclays PLC | 0.00% | Reduce -79.3% | 133,193 | $10.1M |
| Parkman Healthcare Partners LLC | 0.93% | Add +22.9% | 130,069 | $9.8M |
| TD Asset Management Inc | 0.01% | Add +55.3% | 129,290 | $9.8M |
| Federated Hermes, Inc. | 0.02% | New | 127,931 | $9.7M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.02% | Reduce -2.9% | 127,629 | $9.6M |
| Capital World Investors | 0.00% | No change | 127,618 | $9.6M |
| Kennedy Capital Management LLC | 0.20% | Add +0.8% | 124,979 | $9.4M |
| Ameriprise Financial Inc. | 0.00% | Add +19.1% | 122,900 | $9.3M |
| Nuveen, LLC | 0.00% | Add +45.3% | 121,050 | $9.1M |
| Bank of New York Mellon Corp | 0.00% | Add +9.8% | 118,084 | $8.9M |
| Nicholas Investment Partners, LP | 0.71% | New | 112,924 | $8.5M |
| ArrowMark Colorado Holdings LLC | 0.18% | No change | 109,410 | $8.3M |
| Victory Capital Management Inc. | 0.00% | Reduce -50.2% | 108,267 | $8.2M |
| Schroder Investment Management Group | 0.01% | Reduce -51.4% | 105,000 | $8.0M |
| Two Sigma Investments, LP | 0.01% | Reduce -14.0% | 105,241 | $7.9M |
| Neuberger Berman Group LLC | 0.01% | New | 99,648 | $7.5M |
| Granahan Investment Management, LLC | 0.31% | Reduce -28.5% | 94,720 | $7.1M |
| HighVista Strategies LLC | 1.73% | Reduce -16.7% | 89,229 | $6.7M |
| Manufacturers Life Insurance Company, The | 0.01% | Add +27.9% | 80,832 | $6.1M |
| Stempoint Capital LP | 1.04% | New | 80,574 | $6.1M |
| Deutsche Bank AG | 0.00% | Add +3.7% | 79,361 | $6.0M |
| Nomura Holdings Inc. | 0.02% | New | 76,898 | $5.8M |
| SG Americas Securities, LLC | 0.01% | Reduce -45.4% | 73,262 | $5.5M |
| Invesco Ltd. | 0.00% | Add +142.6% | 70,687 | $5.3M |
| Boxer Capital Management, LLC | 1.16% | Add +40.0% | 70,000 | $5.3M |
| Platinum Investment Management Ltd. | 1.21% | Reduce -26.2% | 69,212 | $5.2M |
| D. E. Shaw & Co. | 0.00% | Reduce -37.1% | 63,250 | $4.8M |
| Swiss National Bank | 0.00% | Add +44.9% | 62,900 | $4.7M |
| Simplex Trading, LLC | 0.13% | New | 62,799 | $4.7M |
| Prudential Financial Inc. | 0.00% | Add +322.2% | 54,300 | $4.1M |
| Blackstone Inc. | 0.02% | Reduce -72.8% | 51,827 | $3.9M |
| Marshall Wace, LLP | 0.00% | Add +622.1% | 50,744 | $3.8M |
| Seven Grand Managers, LLC | 0.29% | New | 50,000 | $3.8M |
| Russell Investments Group, Ltd. | 0.00% | Add +14.5% | 49,999 | $3.8M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +59.8% | 49,805 | $3.8M |
| Rafferty Asset Management, LLC | 0.01% | Reduce -26.1% | 48,619 | $3.7M |
| Rhumbline Advisers | 0.00% | Reduce -3.8% | 45,971 | $3.5M |
| Alps Advisors Inc. | 0.02% | Add +99.6% | 44,922 | $3.4M |
| Wells Fargo & Company | 0.00% | Add +93.3% | 42,499 | $3.2M |
| Banque Pictet & Cie SA | 0.03% | New | 41,800 | $3.2M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | Add +19625.7% | 39,846 | $3.0M |
| Aberdeen Group plc | 0.00% | Reduce -34.1% | 36,103 | $2.7M |
| Comerica Bank | 0.01% | Add +0.9% | 35,872 | $2.7M |
| Cinctive Capital Management LP | 0.14% | New | 33,264 | $2.5M |
| Legal & General Group Plc | 0.00% | Add +18.8% | 32,856 | $2.5M |
| California State Teachers Retirement System | 0.00% | Add +43.8% | 30,758 | $2.3M |
| Tudor Investment Corporation | 0.01% | New | 30,039 | $2.3M |
| Schonfeld Strategic Advisors LLC | 0.01% | New | 29,145 | $2.2M |
| Erste Asset Management GmbH | 0.02% | No change | 24,000 | $1.8M |
| New York State Common Retirement Fund | 0.00% | Add +127.4% | 22,484 | $1.7M |
| MetLife Investment Management, LLC | 0.01% | Add +10.8% | 21,311 | $1.6M |
| SummitTX Capital, L.P. | 0.05% | Reduce -21.2% | 20,972 | $1.6M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +11.5% | 20,709 | $1.6M |
| State of Wisconsin Investment Board | 0.00% | Add +150.9% | 20,313 | $1.5M |
| B Group, Inc. | 1.12% | Reduce -42.9% | 20,000 | $1.5M |
| XTX Topco Ltd | 0.04% | Add +225.1% | 19,026 | $1.4M |
| Voya Investment Management LLC | 0.00% | Add +97.3% | 18,492 | $1.4M |
| Profund Advisors LLC | 0.04% | Add +29.0% | 18,276 | $1.4M |
| FORA Capital, LLC | 0.17% | New | 18,200 | $1.4M |
| Moody Aldrich Partners LLC | 0.24% | Reduce -4.7% | 17,164 | $1.3M |
| Sei Investments Co. | 0.00% | New | 16,329 | $1.2M |
| Birchview Capital, LP | 0.71% | No change | 16,000 | $1.2M |
| Qube Research & Technologies Ltd | 0.00% | New | 14,283 | $1.1M |
| Intech Investment Management LLC | 0.01% | No change | 13,701 | $1.0M |
| Legato Capital Management LLC | 0.09% | New | 13,551 | $1.0M |
| Handelsbanken Fonder AB | 0.00% | Add +49.4% | 12,700 | $959K |
| Verition Fund Management LLC | 0.01% | Reduce -74.4% | 12,700 | $959K |
| Connor, Clark & Lunn Investment Management Ltd. | 0.00% | New | 12,689 | $958K |
| Vestmark Advisory Solutions, Inc. | 0.01% | New | 12,674 | $957K |
| Jane Street Group, LLC | 0.00% | Reduce -84.3% | 12,192 | $920K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +32.6% | 11,879 | $897K |
| Teachers Retirement System of the State of Kentucky | 0.01% | No change | 11,644 | $879K |
| LMR Partners LLP | 0.01% | Reduce -39.5% | 11,461 | $865K |
| Man Group plc | 0.00% | New | 11,163 | $843K |
| Neo Ivy Capital Management | 0.13% | New | 10,910 | $823K |
| State of New Jersey Common Pension Fund D | 0.00% | New | 10,879 | $821K |
| AlphaCentric Advisors LLC | 0.81% | — | 10,751 | $811K |
| Police & Firemen's Retirement System of New Jersey | 0.01% | Add +10.6% | 10,330 | $780K |
| BNP Paribas Financial Markets | 0.00% | Reduce -73.9% | 9,965 | $752K |
| ProShare Advisors LLC | 0.00% | Add +30.7% | 9,464 | $714K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 9,350 | $706K |
| Mariner, LLC | 0.00% | Add +54.9% | 9,101 | $687K |
| China Universal Asset Management Co., Ltd. | 0.05% | Add +10.6% | 8,935 | $674K |
| Creative Planning | 0.00% | Add +21.2% | 8,904 | $672K |
| Citigroup Inc. | 0.00% | Add +36.6% | 8,882 | $670K |
| Arizona State Retirement System | 0.00% | Add +32.7% | 8,763 | $661K |
| Glenmede Trust Co. NA | 0.00% | — | 8,512 | $642K |
| Global Endowment Management, LP | 0.07% | No change | 7,797 | $589K |
| Commonwealth Equity Services, LLC | 0.00% | Add +2.2% | 7,151 | $540K |
| Act Capital Management, LLC | 0.43% | — | 7,000 | $528K |
| PSP Research LLC | 0.46% | — | 6,984 | $527K |
| KLP Kapitalforvaltning As | 0.00% | Add +65.8% | 6,800 | $513K |
| Fox Run Management, L.L.C. | 0.07% | New | 6,371 | $481K |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 0.07% | New | 6,324 | $477K |
| DNB Asset Management AS | 0.00% | New | 5,775 | $436K |
| Allspring Global Investments Holdings, LLC | 0.00% | New | 5,435 | $412K |
| Stifel Financial Corp. | 0.00% | Add +3.5% | 5,214 | $394K |
| Public Employees Retirement Association of Colorado | 0.00% | New | 4,919 | $371K |
| Teacher Retirement System of Texas | 0.00% | Reduce -14.3% | 4,705 | $355K |
| Susquehanna International Group, LLP | 0.00% | Reduce -72.2% | 4,634 | $350K |
| Tower Research Capital LLC (TRC) | 0.01% | Add +23.8% | 3,670 | $277K |
| J. Goldman & Co LP | 0.01% | Reduce -94.5% | 3,466 | $262K |
| Virtus Investment Advisers, LLC | 0.07% | Add +27.0% | 3,451 | $260K |
| First Trust Advisors LP | 0.00% | New | 3,418 | $258K |
| Quantbot Technologies LP | 0.01% | Add +38.8% | 3,340 | $252K |
| STRS Ohio | 0.00% | New | 3,300 | $249K |
| Boyer Financial Services, Inc. | 0.25% | — | 3,126 | $237K |
| Ameritas Investment Partners, Inc. | 0.01% | Add +14.3% | 3,126 | $236K |
| Baader Bank Aktiengesellschaft | 0.02% | New | 3,100 | $234K |
| Xponance LLC | 0.00% | New | 3,015 | $228K |
| Vident Advisory, LLC | 0.00% | New | 2,891 | $218K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +49.5% | 2,665 | $201K |
| AlphaQuest LLC | 0.01% | Reduce -48.6% | 2,524 | $191K |
| Quarry LP | 0.03% | New | 2,500 | $189K |
| Persistent Asset Partners Ltd | 0.09% | Reduce -83.5% | 2,445 | $185K |
| Ensign Peak Advisors, Inc | 0.00% | New | 2,250 | $170K |
| Seven Fleet Capital Management LP | 0.09% | — | 1,800 | $136K |
| Amalgamated Bank | 0.00% | Add +14.0% | 1,210 | $91K |
| Royal Bank of Canada | 0.00% | Reduce -71.7% | 1,138 | $85K |
| GF Fund Management Co. LTD. | 0.00% | Add +8.6% | 1,077 | $81K |
| Group One Trading LLC | 0.00% | New | 1,057 | $80K |
| Osaic Holdings, Inc. | 0.00% | Add +74.7% | 959 | $72K |
| ANTIPODES PARTNERS Ltd | 0.00% | Reduce -14.2% | 723 | $55K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -7.2% | 701 | $53K |
| Bessemer Group Inc. | 0.00% | Add +2.2% | 516 | $39K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +45.1% | 399 | $30K |
| Los Angeles Capital Management LLC | 0.00% | New | 490 | $27K |
| US Bancorp \de | 0.00% | Reduce -13.5% | 346 | $26K |
| Rockefeller Capital Management L.P. | 0.00% | New | 337 | $25K |
| Smartleaf Asset Management LLC | 0.00% | Add +173.3% | 276 | $21K |
| Sterling Capital Management LLC | 0.00% | Add +219.0% | 252 | $19K |
| Versant Capital Management, Inc | 0.00% | No change | 229 | $17K |
| GAMMA Investing LLC | 0.00% | Add +51.0% | 216 | $16K |
| Daiwa Securities Group Inc. | 0.00% | No change | 166 | $13K |
| Larson Financial Group LLC | 0.00% | Add +115.1% | 157 | $12K |
| Optiver Holding B.V. | 0.00% | Reduce -42.2% | 156 | $12K |
| Kemnay Advisory Services Inc. | 0.00% | New | 118 | $9K |
| Jones Financial Companies LLLP | 0.00% | No change | 98 | $7K |
| Quadrant Capital Group LLC | 0.00% | No change | 91 | $7K |
| PNC Financial Services Group, Inc. | 0.00% | Add +1.2% | 82 | $6K |
| Rothschild Investment LLC | 0.00% | Add +2.7% | 77 | $6K |
| Red Tortoise LLC | 0.00% | No change | 69 | $5K |
| Exane Asset Management | 0.00% | Reduce -99.9% | 52 | $5K |
| Cwm, LLC | 0.00% | Add +18.4% | 58 | $4K |
| Farther Finance Advisors, LLC | 0.00% | Add +85.2% | 50 | $4K |
| Parkside Financial Bank & Trust | 0.00% | No change | 31 | $2K |
| Cornerstone Financial Management LLC | 0.00% | — | 30 | $2K |
| Arax Advisory Partners | 0.00% | Reduce -69.0% | 26 | $2K |
| Bellevue Asset Management, LLC | 0.00% | Reduce -33.3% | 24 | $2K |
| Hughes Financial Services, LLC | 0.00% | Add +5.9% | 18 | $1K |
| TD Private Client Wealth LLC | 0.00% | No change | 18 | $1K |
| Bare Financial Services, Inc | 0.00% | New | 15 | $1K |
| Signaturefd, LLC | 0.00% | No change | 13 | $981 |
| Blue Trust, Inc. | 0.00% | New | 8 | $604 |
| SBI Securities Co., Ltd. | 0.00% | Reduce -64.7% | 6 | $453 |
| Sunbelt Securities, Inc. | 0.00% | No change | 3 | $226 |
| IFP Advisors, Inc | 0.00% | No change | 2 | $151 |
| Allworth Financial LP | 0.00% | No change | 1 | $76 |
| Covestor Ltd | 0.00% | Reduce -33.3% | 2 | $0 |
"% of holder's portfolio" is APGE's weight in each manager's 13F, not the share of Apogee Therapeutics Inc. the manager owns.