Bicycle Therapeutics PLC-ADRBCYC
13F holders, Q1 2025 (March 31)At the end of Q1 2025, 95 institutions reported holding Bicycle Therapeutics PLC-ADR (BCYC) in their 13F filings, down 2 from Q4 2024. 15 opened new positions and 17 sold out. The largest holders were Baker Bros. Advisors LP ($92.4M), Point72 Asset Management ($31.3M) and FCPM III Services B.V. ($29.3M). 4 famous investors held it, including Steve Cohen (0.1% of Point72 Asset Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).
- Company
- Bicycle Therapeutics PLC-ADR
- CUSIP
- 088786108
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 15 | $9.4M |
| Exits | 17 | $17.9M |
All 13F filers, Q4 2024 → Q1 2025: 3,655,049 shares bought and 3,810,088 shares sold, net −155,039 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 95 holders
| Baker Bros. Advisors LP | 1.03% | No change | 10,885,357 | $92.4M |
| Point72 Asset Management | 0.09% | Reduce -18.9% | 3,692,069 | $31.3M |
| FCPM III Services B.V. | 7.08% | No change | 3,452,330 | $29.3M |
| Armistice Capital, LLC | 0.61% | Add +21.7% | 2,672,000 | $22.7M |
| Westfield Capital Management Co. LP | 0.11% | Add +1.8% | 2,657,305 | $22.6M |
| Siren, L.L.C. | 0.87% | Reduce -1.4% | 1,812,752 | $15.4M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -3.1% | 1,536,584 | $13.0M |
| Long Focus Capital Management, LLC | 0.75% | Add +138.2% | 1,293,753 | $11.0M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.03% | Add +5.5% | 1,219,688 | $10.4M |
| Candriam S.C.A. | 0.06% | Add +10.8% | 1,205,207 | $10.2M |
| Ra Capital Management, L.P. | 0.16% | No change | 1,093,477 | $9.3M |
| Morgan Stanley | 0.00% | Add +16.0% | 999,837 | $8.5M |
| EcoR1 Capital, LLC | 0.46% | No change | 910,000 | $7.7M |
| Deep Track Capital, LP | 0.21% | Reduce -39.9% | 767,016 | $6.5M |
| Principal Financial Group Inc. | 0.00% | Add +55.3% | 631,260 | $5.4M |
| Tybourne Capital Management (hk) Ltd. | 20.77% | Reduce -54.6% | 576,343 | $4.9M |
| Bank of America Corp. | 0.00% | Add +43.5% | 563,559 | $4.8M |
| AXA S.A. | 0.02% | Reduce -0.1% | 553,682 | $4.7M |
| Millennium Management | 0.00% | Add +156.5% | 453,428 | $3.8M |
| Jefferies Financial Group Inc. | 0.06% | New | 408,889 | $3.5M |
| Woodline Partners LP | 0.02% | New | 363,751 | $3.1M |
| BlackRock, Inc. | 0.00% | Reduce -11.6% | 322,876 | $2.7M |
| Renaissance Technologies | 0.00% | Add +11.9% | 301,500 | $2.6M |
| Platinum Investment Management Ltd. | 0.14% | Reduce -6.9% | 287,599 | $2.4M |
| Silvercrest Asset Management Group LLC | 0.02% | Add +92.9% | 265,693 | $2.3M |
| Palo Alto Investors LP | 0.40% | No change | 248,934 | $2.1M |
| Handelsbanken Fonder AB | 0.01% | No change | 215,900 | $1.8M |
| Pinnacle Associates Ltd. | 0.03% | Reduce -5.5% | 214,278 | $1.8M |
| TD Asset Management Inc | 0.00% | Reduce -10.6% | 193,092 | $1.6M |
| Aquilo Capital Management, LLC | 3.93% | Reduce -22.6% | 171,695 | $1.5M |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0.03% | Add +85.4% | 148,722 | $1.3M |
| Harbor Capital Advisors, Inc. | 0.06% | Add +12.6% | 148,129 | $1.3M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +11.1% | 138,249 | $1.2M |
| Legal & General Group Plc | 0.00% | Reduce -2.5% | 135,658 | $1.2M |
| Citadel Advisors | 0.00% | Reduce -9.8% | 130,070 | $1.1M |
| Acadian Asset Management LLC | 0.00% | New | 126,062 | $1.1M |
| State Street Corp. | 0.00% | Reduce -2.4% | 85,653 | $727K |
| Caption Management, LLC | 0.03% | Reduce -50.0% | 81,559 | $692K |
| DAFNA Capital Management LLC | 0.20% | Reduce -33.1% | 80,799 | $686K |
| UBS Group AG | 0.00% | Reduce -45.1% | 72,702 | $617K |
| Nan Fung Group Holdings Ltd | 0.48% | No change | 68,943 | $585K |
| Shay Capital LLC | 0.15% | New | 60,000 | $509K |
| Moore Capital Management, LP | 0.02% | New | 50,000 | $425K |
| Cubist Systematic Strategies, LLC | 0.01% | Reduce -5.3% | 47,249 | $401K |
| Skandinaviska Enskilda Banken AB (publ) | 0.00% | No change | 42,729 | $363K |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 30,000 | $256K |
| EntryPoint Capital, LLC | 0.11% | Reduce -34.2% | 28,857 | $245K |
| Goldman Sachs Group Inc. | 0.00% | New | 25,192 | $214K |
| Woodstock Corp. | 0.02% | No change | 24,981 | $212K |
| Geode Capital Management, LLC | 0.00% | Reduce -44.9% | 21,377 | $181K |
| Tocqueville Asset Management L.P. | 0.00% | Add +24.5% | 18,300 | $155K |
| Royal Bank of Canada | 0.00% | Add +83.6% | 17,940 | $152K |
| Portland Investment Counsel Inc. | 0.04% | New | 15,000 | $127K |
| Erste Asset Management GmbH | 0.00% | No change | 14,000 | $126K |
| Horizon Kinetics Asset Management LLC | 0.00% | No change | 14,396 | $122K |
| Cerity Partners LLC | 0.00% | New | 13,350 | $113K |
| PNC Financial Services Group, Inc. | 0.00% | Add +1.4% | 13,080 | $111K |
| Exchange Traded Concepts, LLC | 0.00% | Add +90.3% | 12,764 | $108K |
| Envestnet Asset Management Inc. | 0.00% | New | 12,420 | $105K |
| Gsa Capital Partners LLP | 0.01% | New | 11,952 | $101K |
| Crossmark Global Holdings, Inc. | 0.00% | Add +0.2% | 11,400 | $97K |
| Sei Investments Co. | 0.00% | New | 10,637 | $90K |
| China Universal Asset Management Co., Ltd. | 0.01% | Reduce -5.3% | 8,833 | $75K |
| Virtus Investment Advisers, LLC | 0.02% | New | 8,162 | $69K |
| JPMorgan Chase & Co. | 0.00% | Reduce -8.6% | 7,044 | $60K |
| Deutsche Bank AG | 0.00% | No change | 6,417 | $54K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | New | 5,100 | $43K |
| Barclays PLC | 0.00% | Add +26.6% | 3,308 | $28K |
| Natixis | 0.00% | Reduce -7.5% | 2,126 | $18K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Reduce -0.1% | 1,464 | $13K |
| Rhumbline Advisers | 0.00% | Add +12.7% | 1,304 | $11K |
| Assetmark, Inc. | 0.00% | Add +1.8% | 1,282 | $11K |
| BNP Paribas Financial Markets | 0.00% | Add +78.1% | 1,211 | $10K |
| GF Fund Management Co. LTD. | 0.00% | Add +21.9% | 1,126 | $10K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +16.9% | 1,081 | $9K |
| GAMMA Investing LLC | 0.00% | Add +15.4% | 1,058 | $9K |
| Citigroup Inc. | 0.00% | Add +9.4% | 689 | $6K |
| Manchester Capital Management LLC | 0.00% | No change | 590 | $5K |
| Simplex Trading, LLC | 0.00% | New | 571 | $4K |
| HighMark Wealth Management LLC | 0.00% | Reduce -90.2% | 435 | $4K |
| FMR LLC | 0.00% | No change | 316 | $3K |
| Jones Financial Companies LLLP | 0.00% | Add +66.7% | 250 | $2K |
| SVB Wealth LLC | 0.00% | New | 210 | $2K |
| Winch Advisory Services, LLC | 0.00% | No change | 172 | $1K |
| Group One Trading LLC | 0.00% | Reduce -64.4% | 166 | $1K |
| Daiwa Securities Group Inc. | 0.00% | No change | 103 | $1K |
| TD Waterhouse Canada Inc. | 0.00% | No change | 100 | $785 |
| Federation des caisses Desjardins du Quebec | 0.00% | No change | 61 | $518 |
| Bell Investment Advisors, Inc | 0.00% | No change | 22 | $187 |
| Osaic Holdings, Inc. | 0.00% | Reduce -97.6% | 18 | $152 |
| EverSource Wealth Advisors, LLC | 0.00% | Reduce -45.8% | 13 | $110 |
| Blue Trust, Inc. | 0.00% | No change | 11 | $93 |
| Steward Partners Investment Advisory, LLC | 0.00% | No change | 10 | $85 |
| SBI Securities Co., Ltd. | 0.00% | Reduce -14.3% | 6 | $51 |
| Caitong International Asset Management Co., Ltd | 0.00% | Reduce -98.7% | 2 | $17 |
"% of holder's portfolio" is BCYC's weight in each manager's 13F, not the share of Bicycle Therapeutics PLC-ADR the manager owns.