Bicycle Therapeutics PLC-ADRBCYC

13F holders, Q1 2025 (March 31)
95holders −2
15new positions
17sold out
4famous investors
$8.49avg. 13F price*

At the end of Q1 2025, 95 institutions reported holding Bicycle Therapeutics PLC-ADR (BCYC) in their 13F filings, down 2 from Q4 2024. 15 opened new positions and 17 sold out. The largest holders were Baker Bros. Advisors LP ($92.4M), Point72 Asset Management ($31.3M) and FCPM III Services B.V. ($29.3M). 4 famous investors held it, including Steve Cohen (0.1% of Point72 Asset Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).

Company
Bicycle Therapeutics PLC-ADR
CUSIP
088786108
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150 Q1 2024: 95Q1 2024Q2 2024: 107Q2 2024Q3 2024: 105Q3 2024Q4 2024: 97Q4 2024Q1 2025: 95Q1 2025Q2 2025: 110Q2 2025Q3 2025: 99Q3 2025Q4 2025: 109Q4 2025Q1 2026: 98Q1 2026Q2 2026: 103Q2 2026

Total Exit/New Position Q4 2024 → Q1 2025

InstitutionsTotal Value
New Positions15$9.4M
Exits17$17.9M

All 13F filers, Q4 2024 → Q1 2025: 3,655,049 shares bought and 3,810,088 shares sold, net −155,039 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 95 holders

Baker Bros. Advisors LP 1.03% No change 10,885,357 $92.4M
Point72 Asset Management 0.09% Reduce -18.9% 3,692,069 $31.3M
FCPM III Services B.V. 7.08% No change 3,452,330 $29.3M
Armistice Capital, LLC 0.61% Add +21.7% 2,672,000 $22.7M
Westfield Capital Management Co. LP 0.11% Add +1.8% 2,657,305 $22.6M
Siren, L.L.C. 0.87% Reduce -1.4% 1,812,752 $15.4M
T. Rowe Price Associates Inc. 0.00% Reduce -3.1% 1,536,584 $13.0M
Long Focus Capital Management, LLC 0.75% Add +138.2% 1,293,753 $11.0M
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.03% Add +5.5% 1,219,688 $10.4M
Candriam S.C.A. 0.06% Add +10.8% 1,205,207 $10.2M
Ra Capital Management, L.P. 0.16% No change 1,093,477 $9.3M
Morgan Stanley 0.00% Add +16.0% 999,837 $8.5M
EcoR1 Capital, LLC 0.46% No change 910,000 $7.7M
Deep Track Capital, LP 0.21% Reduce -39.9% 767,016 $6.5M
Principal Financial Group Inc. 0.00% Add +55.3% 631,260 $5.4M
Tybourne Capital Management (hk) Ltd. 20.77% Reduce -54.6% 576,343 $4.9M
Bank of America Corp. 0.00% Add +43.5% 563,559 $4.8M
AXA S.A. 0.02% Reduce -0.1% 553,682 $4.7M
Millennium Management 0.00% Add +156.5% 453,428 $3.8M
Jefferies Financial Group Inc. 0.06% New 408,889 $3.5M
Woodline Partners LP 0.02% New 363,751 $3.1M
BlackRock, Inc. 0.00% Reduce -11.6% 322,876 $2.7M
Renaissance Technologies 0.00% Add +11.9% 301,500 $2.6M
Platinum Investment Management Ltd. 0.14% Reduce -6.9% 287,599 $2.4M
Silvercrest Asset Management Group LLC 0.02% Add +92.9% 265,693 $2.3M
Palo Alto Investors LP 0.40% No change 248,934 $2.1M
Handelsbanken Fonder AB 0.01% No change 215,900 $1.8M
Pinnacle Associates Ltd. 0.03% Reduce -5.5% 214,278 $1.8M
TD Asset Management Inc 0.00% Reduce -10.6% 193,092 $1.6M
Aquilo Capital Management, LLC 3.93% Reduce -22.6% 171,695 $1.5M
OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.03% Add +85.4% 148,722 $1.3M
Harbor Capital Advisors, Inc. 0.06% Add +12.6% 148,129 $1.3M
Manufacturers Life Insurance Company, The 0.00% Add +11.1% 138,249 $1.2M
Legal & General Group Plc 0.00% Reduce -2.5% 135,658 $1.2M
Citadel Advisors 0.00% Reduce -9.8% 130,070 $1.1M
Acadian Asset Management LLC 0.00% New 126,062 $1.1M
State Street Corp. 0.00% Reduce -2.4% 85,653 $727K
Caption Management, LLC 0.03% Reduce -50.0% 81,559 $692K
DAFNA Capital Management LLC 0.20% Reduce -33.1% 80,799 $686K
UBS Group AG 0.00% Reduce -45.1% 72,702 $617K
Nan Fung Group Holdings Ltd 0.48% No change 68,943 $585K
Shay Capital LLC 0.15% New 60,000 $509K
Moore Capital Management, LP 0.02% New 50,000 $425K
Cubist Systematic Strategies, LLC 0.01% Reduce -5.3% 47,249 $401K
Skandinaviska Enskilda Banken AB (publ) 0.00% No change 42,729 $363K
DekaBank Deutsche Girozentrale 0.00% No change 30,000 $256K
EntryPoint Capital, LLC 0.11% Reduce -34.2% 28,857 $245K
Goldman Sachs Group Inc. 0.00% New 25,192 $214K
Woodstock Corp. 0.02% No change 24,981 $212K
Geode Capital Management, LLC 0.00% Reduce -44.9% 21,377 $181K
Tocqueville Asset Management L.P. 0.00% Add +24.5% 18,300 $155K
Royal Bank of Canada 0.00% Add +83.6% 17,940 $152K
Portland Investment Counsel Inc. 0.04% New 15,000 $127K
Erste Asset Management GmbH 0.00% No change 14,000 $126K
Horizon Kinetics Asset Management LLC 0.00% No change 14,396 $122K
Cerity Partners LLC 0.00% New 13,350 $113K
PNC Financial Services Group, Inc. 0.00% Add +1.4% 13,080 $111K
Exchange Traded Concepts, LLC 0.00% Add +90.3% 12,764 $108K
Envestnet Asset Management Inc. 0.00% New 12,420 $105K
Gsa Capital Partners LLP 0.01% New 11,952 $101K
Crossmark Global Holdings, Inc. 0.00% Add +0.2% 11,400 $97K
Sei Investments Co. 0.00% New 10,637 $90K
China Universal Asset Management Co., Ltd. 0.01% Reduce -5.3% 8,833 $75K
Virtus Investment Advisers, LLC 0.02% New 8,162 $69K
JPMorgan Chase & Co. 0.00% Reduce -8.6% 7,044 $60K
Deutsche Bank AG 0.00% No change 6,417 $54K
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% New 5,100 $43K
Barclays PLC 0.00% Add +26.6% 3,308 $28K
Natixis 0.00% Reduce -7.5% 2,126 $18K
Mirae Asset Global Investments Co., Ltd. 0.00% Reduce -0.1% 1,464 $13K
Rhumbline Advisers 0.00% Add +12.7% 1,304 $11K
Assetmark, Inc. 0.00% Add +1.8% 1,282 $11K
BNP Paribas Financial Markets 0.00% Add +78.1% 1,211 $10K
GF Fund Management Co. LTD. 0.00% Add +21.9% 1,126 $10K
Tower Research Capital LLC (TRC) 0.00% Add +16.9% 1,081 $9K
GAMMA Investing LLC 0.00% Add +15.4% 1,058 $9K
Citigroup Inc. 0.00% Add +9.4% 689 $6K
Manchester Capital Management LLC 0.00% No change 590 $5K
Simplex Trading, LLC 0.00% New 571 $4K
HighMark Wealth Management LLC 0.00% Reduce -90.2% 435 $4K
FMR LLC 0.00% No change 316 $3K
Jones Financial Companies LLLP 0.00% Add +66.7% 250 $2K
SVB Wealth LLC 0.00% New 210 $2K
Winch Advisory Services, LLC 0.00% No change 172 $1K
Group One Trading LLC 0.00% Reduce -64.4% 166 $1K
Daiwa Securities Group Inc. 0.00% No change 103 $1K
TD Waterhouse Canada Inc. 0.00% No change 100 $785
Federation des caisses Desjardins du Quebec 0.00% No change 61 $518
Bell Investment Advisors, Inc 0.00% No change 22 $187
Osaic Holdings, Inc. 0.00% Reduce -97.6% 18 $152
EverSource Wealth Advisors, LLC 0.00% Reduce -45.8% 13 $110
Blue Trust, Inc. 0.00% No change 11 $93
Steward Partners Investment Advisory, LLC 0.00% No change 10 $85
SBI Securities Co., Ltd. 0.00% Reduce -14.3% 6 $51
Caitong International Asset Management Co., Ltd 0.00% Reduce -98.7% 2 $17

"% of holder's portfolio" is BCYC's weight in each manager's 13F, not the share of Bicycle Therapeutics PLC-ADR the manager owns.