Bicycle Therapeutics PLC-ADRBCYC
13F holders, Q3 2025 (September 30)99holders −11
10new positions
21sold out
4famous investors
$7.74avg. 13F price*
At the end of Q3 2025, 99 institutions reported holding Bicycle Therapeutics PLC-ADR (BCYC) in their 13F filings, down 11 from Q2 2025. 10 opened new positions and 21 sold out. The largest holders were Baker Bros. Advisors LP ($84.3M), FCPM III Services B.V. ($26.7M) and Armistice Capital, LLC ($23.0M). 4 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).
- Company
- Bicycle Therapeutics PLC-ADR
- CUSIP
- 088786108
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 10 | $1.7M |
| Exits | 21 | $30.6M |
All 13F filers, Q2 2025 → Q3 2025: 2,804,273 shares bought and 7,098,494 shares sold, net −4,294,221 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 99 holders
| Baker Bros. Advisors LP | 0.61% | No change | 10,885,357 | $84.3M |
| FCPM III Services B.V. | 5.34% | No change | 3,452,330 | $26.7M |
| Armistice Capital, LLC | 0.72% | Add +6.4% | 2,978,000 | $23.0M |
| Westfield Capital Management Co. LP | 0.10% | Add +6.2% | 2,952,543 | $22.9M |
| Siren, L.L.C. | 0.61% | No change | 2,012,752 | $15.6M |
| Long Focus Capital Management, LLC | 0.63% | Add +7.7% | 1,418,695 | $11.0M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -5.7% | 1,384,794 | $10.7M |
| Acadian Asset Management LLC | 0.02% | Add +88.2% | 1,314,556 | $10.2M |
| Candriam S.C.A. | 0.05% | No change | 1,172,387 | $9.1M |
| Principal Financial Group Inc. | 0.00% | Add +64.7% | 1,148,402 | $8.9M |
| Millennium Management | 0.01% | Reduce -26.9% | 1,054,746 | $8.2M |
| Morgan Stanley | 0.00% | Reduce -20.7% | 822,705 | $6.4M |
| Bank of America Corp. | 0.00% | Reduce -28.8% | 591,535 | $4.6M |
| Renaissance Technologies | 0.01% | Add +62.9% | 518,700 | $4.0M |
| Silvercrest Asset Management Group LLC | 0.02% | Add +79.5% | 476,976 | $3.7M |
| Point72 Asset Management | 0.01% | Reduce -75.7% | 430,900 | $3.3M |
| Jefferies Financial Group Inc. | 0.03% | Reduce -12.8% | 401,926 | $3.1M |
| BlackRock, Inc. | 0.00% | Add +6.8% | 282,418 | $2.2M |
| Palo Alto Investors LP | 0.32% | Reduce -11.2% | 221,071 | $1.7M |
| Legal & General Group Plc | 0.00% | Add +13.2% | 197,917 | $1.5M |
| Pinnacle Associates Ltd. | 0.02% | Add +14.3% | 196,618 | $1.5M |
| Eversept Partners, LP | 0.12% | Reduce -8.1% | 194,440 | $1.5M |
| Citadel Advisors | 0.00% | Add +35.5% | 189,027 | $1.5M |
| Platinum Investment Management Ltd. | 0.09% | Reduce -35.3% | 184,603 | $1.4M |
| Two Sigma Investments, LP | 0.00% | Add +228.4% | 184,537 | $1.4M |
| TD Asset Management Inc | 0.00% | Reduce -7.8% | 178,092 | $1.4M |
| Two Sigma Advisers, LP | 0.00% | Add +123.2% | 156,700 | $1.2M |
| Birchview Capital, LP | 0.90% | New | 154,000 | $1.2M |
| Handelsbanken Fonder AB | 0.00% | Reduce -25.0% | 150,000 | $1.2M |
| Manufacturers Life Insurance Company, The | 0.00% | No change | 140,492 | $1.1M |
| Rangeley Capital, LLC | 0.97% | Add +73.3% | 130,000 | $1.0M |
| Moore Capital Management, LP | 0.02% | Add +66.7% | 125,000 | $968K |
| Cubist Systematic Strategies, LLC | 0.01% | Add +17.9% | 103,410 | $800K |
| Jane Street Group, LLC | 0.00% | Add +353.2% | 102,459 | $793K |
| Monimus Capital Management, LP | 0.49% | No change | 85,224 | $660K |
| State Street Corp. | 0.00% | Add +12.7% | 74,405 | $576K |
| Nan Fung Group Holdings Ltd | 0.90% | No change | 68,943 | $534K |
| DAFNA Capital Management LLC | 0.13% | No change | 64,492 | $499K |
| Sei Investments Co. | 0.00% | Add +361.2% | 49,056 | $380K |
| State of Tennessee, Department of Treasury | 0.00% | Add +211.8% | 44,842 | $347K |
| Harbor Capital Advisors, Inc. | 0.02% | Reduce -70.2% | 41,368 | $320K |
| Man Group plc | 0.00% | Add +42.6% | 40,891 | $316K |
| Geode Capital Management, LLC | 0.00% | Reduce -1.2% | 39,925 | $309K |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 30,000 | $220K |
| Dynamic Technology Lab Private Ltd | 0.04% | Reduce -39.1% | 27,959 | $216K |
| Quadrature Capital Ltd | 0.00% | Add +57.3% | 27,894 | $216K |
| Susquehanna International Group, LLP | 0.00% | Add +0.2% | 26,629 | $206K |
| Alps Advisors Inc. | 0.00% | Reduce -6.3% | 24,123 | $187K |
| Woodstock Corp. | 0.02% | No change | 23,927 | $185K |
| Jump Financial, LLC | 0.00% | Add +28.0% | 21,421 | $166K |
| State of New Jersey Common Pension Fund D | 0.00% | New | 20,105 | $156K |
| Portland Investment Counsel Inc. | 0.03% | No change | 15,000 | $116K |
| Ameriprise Financial Inc. | 0.00% | Add +21.7% | 14,972 | $116K |
| Horizon Kinetics Asset Management LLC | 0.00% | Add +4.4% | 14,396 | $111K |
| Cerity Partners LLC | 0.00% | No change | 14,350 | $111K |
| Federation des caisses Desjardins du Quebec | 0.00% | Add +48.9% | 14,302 | $111K |
| Erste Asset Management GmbH | 0.00% | No change | 14,000 | $107K |
| Engineers Gate Manager LP | 0.00% | Reduce -12.9% | 13,421 | $104K |
| Squarepoint Ops LLC | 0.00% | Add +11.7% | 13,259 | $103K |
| Virtus Investment Advisers, LLC | 0.03% | Add +21.0% | 13,094 | $101K |
| PNC Financial Services Group, Inc. | 0.00% | No change | 13,080 | $101K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | New | 12,953 | $100K |
| Royal Bank of Canada | 0.00% | Add +22.9% | 12,733 | $99K |
| Graham Capital Management, L.P. | 0.01% | Reduce -5.5% | 12,375 | $96K |
| Tocqueville Asset Management L.P. | 0.00% | Reduce -46.3% | 12,300 | $95K |
| XTX Topco Ltd | 0.00% | New | 11,648 | $90K |
| Crossmark Global Holdings, Inc. | 0.00% | Add +0.0% | 11,390 | $88K |
| UBS Group AG | 0.00% | Reduce -65.9% | 11,373 | $88K |
| FNY Investment Advisers, LLC | 0.03% | New | 10,500 | $81K |
| Commonwealth of Pennsylvania Public School Empls Retrmt SYS | 0.00% | New | 10,116 | $78K |
| JPMorgan Chase & Co. | 0.00% | Add +6.4% | 8,127 | $63K |
| China Universal Asset Management Co., Ltd. | 0.01% | Reduce -8.6% | 8,104 | $63K |
| Assetmark, Inc. | 0.00% | Add +74.9% | 3,625 | $28K |
| Rhumbline Advisers | 0.00% | Add +9.0% | 3,275 | $25K |
| Citigroup Inc. | 0.00% | Add +184.9% | 2,601 | $20K |
| Barclays PLC | 0.00% | Reduce -34.6% | 2,272 | $18K |
| GAMMA Investing LLC | 0.00% | Add +42.2% | 2,116 | $16K |
| Natixis | 0.00% | No change | 1,947 | $15K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +4.8% | 1,787 | $14K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -60.0% | 1,665 | $13K |
| Clearstead Advisors, LLC | 0.00% | No change | 1,393 | $11K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -11.6% | 995 | $8K |
| BNP Paribas Financial Markets | 0.00% | Add +53.0% | 811 | $6K |
| Walleye Trading LLC | 0.00% | New | 630 | $5K |
| Manchester Capital Management LLC | 0.00% | No change | 590 | $5K |
| HighMark Wealth Management LLC | 0.00% | No change | 435 | $3K |
| FMR LLC | 0.00% | No change | 316 | $2K |
| Jones Financial Companies LLLP | 0.00% | No change | 250 | $2K |
| Wells Fargo & Company | 0.00% | No change | 200 | $2K |
| Winch Advisory Services, LLC | 0.00% | No change | 172 | $1K |
| Toth Financial Advisory Corp. | 0.00% | No change | 150 | $1K |
| Daiwa Securities Group Inc. | 0.00% | No change | 103 | $1K |
| Principal Securities, Inc. | 0.00% | No change | 18 | $139 |
| Osaic Holdings, Inc. | 0.00% | No change | 18 | $132 |
| Blue Trust, Inc. | 0.00% | No change | 11 | $85 |
| SBI Securities Co., Ltd. | 0.00% | Add +16.7% | 7 | $54 |
| EverSource Wealth Advisors, LLC | 0.00% | New | 6 | $46 |
| Rockefeller Capital Management L.P. | 0.00% | New | 5 | $39 |
| Caitlin John, LLC | 0.00% | New | 2 | $15 |
"% of holder's portfolio" is BCYC's weight in each manager's 13F, not the share of Bicycle Therapeutics PLC-ADR the manager owns.