Bicycle Therapeutics PLC-ADRBCYC

13F holders, Q4 2024 (December 31)
97holders −8
11new positions
23sold out
4famous investors
$14.00avg. 13F price*

At the end of Q4 2024, 97 institutions reported holding Bicycle Therapeutics PLC-ADR (BCYC) in their 13F filings, down 8 from Q3 2024. 11 opened new positions and 23 sold out. The largest holders were Baker Bros. Advisors LP ($152.4M), Point72 Asset Management ($63.8M) and FCPM III Services B.V. ($48.3M). 4 famous investors held it, including Steve Cohen (0.2% of Point72 Asset Management's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).

Company
Bicycle Therapeutics PLC-ADR
CUSIP
088786108
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150 Q1 2024: 95Q1 2024Q2 2024: 107Q2 2024Q3 2024: 105Q3 2024Q4 2024: 97Q4 2024Q1 2025: 95Q1 2025Q2 2025: 110Q2 2025Q3 2025: 99Q3 2025Q4 2025: 109Q4 2025Q1 2026: 98Q1 2026Q2 2026: 103Q2 2026

Total Exit/New Position Q3 2024 → Q4 2024

InstitutionsTotal Value
New Positions11$42.0M
Exits23$106.2M

All 13F filers, Q3 2024 → Q4 2024: 11,289,561 shares bought and 9,936,497 shares sold, net +1,353,064 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 97 holders

Baker Bros. Advisors LP 1.65% Add +15.8% 10,885,357 $152.4M
Point72 Asset Management 0.18% Add +406.2% 4,554,900 $63.8M
FCPM III Services B.V. 8.16% Add +47.5% 3,452,330 $48.3M
Westfield Capital Management Co. LP 0.16% Add +41.0% 2,610,337 $36.5M
Armistice Capital, LLC 0.72% Add +12.3% 2,196,000 $30.7M
Siren, L.L.C. 1.14% New 1,839,398 $25.8M
T. Rowe Price Associates Inc. 0.00% Reduce -8.0% 1,585,127 $22.2M
Deep Track Capital, LP 0.67% Reduce -64.0% 1,276,081 $17.9M
Tybourne Capital Management (hk) Ltd. 4.46% Reduce -9.0% 1,269,535 $17.8M
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.04% Add +52.1% 1,155,651 $16.2M
Ra Capital Management, L.P. 0.20% Reduce -51.5% 1,093,477 $15.3M
Candriam S.C.A. 0.09% Add +3.5% 1,087,876 $15.2M
EcoR1 Capital, LLC 0.51% No change 910,000 $12.7M
Morgan Stanley 0.00% Reduce -36.1% 862,137 $12.1M
AXA S.A. 0.02% Reduce -0.1% 553,959 $7.8M
Long Focus Capital Management, LLC 0.58% New 543,092 $7.6M
Principal Financial Group Inc. 0.00% Reduce -8.3% 406,470 $5.7M
Bank of America Corp. 0.00% Add +2.1% 392,859 $5.5M
BlackRock, Inc. 0.00% Reduce -12.9% 365,408 $5.1M
Parkman Healthcare Partners LLC 0.66% Reduce -20.9% 352,481 $4.9M
Platinum Investment Management Ltd. 0.25% Add +13.6% 309,059 $4.3M
Verition Fund Management LLC 0.02% Add +32.1% 280,327 $3.9M
Renaissance Technologies 0.01% Reduce -1.1% 269,500 $3.8M
Palo Alto Investors LP 0.54% Add +317.8% 248,934 $3.5M
Pinnacle Associates Ltd. 0.04% New 226,742 $3.2M
Aquilo Capital Management, LLC 5.32% Add +22.0% 221,911 $3.1M
TD Asset Management Inc 0.00% Reduce -2.4% 216,016 $3.0M
Handelsbanken Fonder AB 0.01% Reduce -1.3% 215,900 $3.0M
Perceptive Advisors LLC 0.08% Reduce -23.0% 197,108 $2.8M
Millennium Management 0.00% New 176,757 $2.5M
Caption Management, LLC 0.09% New 163,076 $2.3M
Citadel Advisors 0.00% Add +40.4% 144,230 $2.0M
Legal & General Group Plc 0.00% Reduce -41.8% 139,075 $1.9M
Silvercrest Asset Management Group LLC 0.01% Reduce -1.0% 137,740 $1.9M
UBS Group AG 0.00% Add +997.0% 132,361 $1.9M
Harbor Capital Advisors, Inc. 0.08% Reduce -1.6% 131,505 $1.8M
Manufacturers Life Insurance Company, The 0.00% Reduce -4.0% 124,497 $1.7M
HighVista Strategies LLC 0.65% Reduce -10.8% 124,430 $1.7M
DAFNA Capital Management LLC 0.43% Reduce -1.1% 120,799 $1.7M
Springhill Fund Asset Management (HK) Co Ltd 2.65% — 116,400 $1.6M
State Street Corp. 0.00% Add +1.7% 87,765 $1.2M
OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.03% Add +123.0% 80,236 $1.1M
Nan Fung Group Holdings Ltd 0.83% Add +118.3% 68,943 $965K
Cubist Systematic Strategies, LLC 0.01% Reduce -36.5% 49,899 $699K
Voya Investment Management LLC 0.00% Reduce -54.0% 48,420 $678K
EntryPoint Capital, LLC 0.26% New 43,873 $614K
Skandinaviska Enskilda Banken AB (publ) 0.00% No change 42,729 $603K
Schonfeld Strategic Advisors LLC 0.00% Reduce -90.0% 42,500 $595K
Altium Capital Management LLC 0.18% Reduce -52.5% 40,352 $565K
Geode Capital Management, LLC 0.00% Add +1.3% 38,815 $543K
DekaBank Deutsche Girozentrale 0.00% No change 30,000 $414K
Woodstock Corp. 0.03% No change 24,981 $350K
Allianz Asset Management GmbH 0.00% No change 24,600 $344K
Jane Street Group, LLC 0.00% Add +18.9% 23,991 $336K
Wexford Capital LP 0.06% Reduce -48.7% 17,879 $250K
Tocqueville Asset Management L.P. 0.00% Reduce -4.5% 14,700 $206K
Erste Asset Management GmbH 0.00% No change 14,000 $204K
Horizon Kinetics Asset Management LLC 0.00% Add +4.4% 14,396 $202K
PNC Financial Services Group, Inc. 0.00% No change 12,900 $181K
Crossmark Global Holdings, Inc. 0.00% Add +0.1% 11,378 $159K
Royal Bank of Canada 0.00% Add +2010.8% 9,773 $137K
China Universal Asset Management Co., Ltd. 0.01% Add +30.7% 9,329 $131K
JPMorgan Chase & Co. 0.00% Reduce -8.5% 7,707 $108K
Exchange Traded Concepts, LLC 0.00% No change 6,707 $94K
Deutsche Bank AG 0.00% Reduce -20.5% 6,417 $90K
HighMark Wealth Management LLC 0.04% No change 4,435 $62K
Avior Wealth Management, LLC 0.00% New 4,043 $57K
Virtus Advisers, LLC 0.02% Reduce -6.7% 3,535 $49K
Barclays PLC 0.00% Add +878.3% 2,612 $37K
Natixis 0.00% Reduce -16.0% 2,298 $33K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +9.2% 1,466 $21K
Assetmark, Inc. 0.00% Reduce -17.1% 1,260 $18K
Rhumbline Advisers 0.00% Add +5.2% 1,157 $16K
Coppell Advisory Solutions LLC 0.00% No change 1,076 $15K
Tower Research Capital LLC (TRC) 0.00% Add +47.1% 925 $13K
GF Fund Management Co. LTD. 0.00% — 924 $13K
GAMMA Investing LLC 0.00% Reduce -54.7% 917 $13K
Osaic Holdings, Inc. 0.00% Reduce -27.1% 760 $11K
BNP Paribas Financial Markets 0.00% Reduce -14.8% 680 $10K
Citigroup Inc. 0.00% Reduce -5.7% 630 $9K
Manchester Capital Management LLC 0.00% No change 590 $8K
Group One Trading LLC 0.00% New 466 $7K
FMR LLC 0.00% Reduce -99.8% 316 $4K
R Squared Ltd 0.00% — 180 $3K
Winch Advisory Services, LLC 0.00% No change 172 $2K
Jones Financial Companies LLLP 0.00% Add +50.0% 150 $2K
Caitong International Asset Management Co., Ltd 0.00% — 148 $2K
AdvisorNet Financial, Inc 0.00% New 100 $1K
TD Waterhouse Canada Inc. 0.00% New 100 $1K
Daiwa Securities Group Inc. 0.00% No change 103 $1K
Federation des caisses Desjardins du Quebec 0.00% No change 61 $854
EverSource Wealth Advisors, LLC 0.00% Add +20.0% 24 $336
Bell Investment Advisors, Inc 0.00% No change 22 $308
Caitlin John, LLC 0.00% No change 14 $196
Blue Trust, Inc. 0.00% Reduce -97.9% 11 $154
Steward Partners Investment Advisory, LLC 0.00% New 10 $140
SBI Securities Co., Ltd. 0.00% — 7 $98

"% of holder's portfolio" is BCYC's weight in each manager's 13F, not the share of Bicycle Therapeutics PLC-ADR the manager owns.