Bicycle Therapeutics PLC-ADRBCYC
13F holders, Q4 2024 (December 31)At the end of Q4 2024, 97 institutions reported holding Bicycle Therapeutics PLC-ADR (BCYC) in their 13F filings, down 8 from Q3 2024. 11 opened new positions and 23 sold out. The largest holders were Baker Bros. Advisors LP ($152.4M), Point72 Asset Management ($63.8M) and FCPM III Services B.V. ($48.3M). 4 famous investors held it, including Steve Cohen (0.2% of Point72 Asset Management's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Bicycle Therapeutics PLC-ADR
- CUSIP
- 088786108
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2024 → Q4 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 11 | $42.0M |
| Exits | 23 | $106.2M |
All 13F filers, Q3 2024 → Q4 2024: 11,289,561 shares bought and 9,936,497 shares sold, net +1,353,064 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 97 holders
| Baker Bros. Advisors LP | 1.65% | Add +15.8% | 10,885,357 | $152.4M |
| Point72 Asset Management | 0.18% | Add +406.2% | 4,554,900 | $63.8M |
| FCPM III Services B.V. | 8.16% | Add +47.5% | 3,452,330 | $48.3M |
| Westfield Capital Management Co. LP | 0.16% | Add +41.0% | 2,610,337 | $36.5M |
| Armistice Capital, LLC | 0.72% | Add +12.3% | 2,196,000 | $30.7M |
| Siren, L.L.C. | 1.14% | New | 1,839,398 | $25.8M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -8.0% | 1,585,127 | $22.2M |
| Deep Track Capital, LP | 0.67% | Reduce -64.0% | 1,276,081 | $17.9M |
| Tybourne Capital Management (hk) Ltd. | 4.46% | Reduce -9.0% | 1,269,535 | $17.8M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.04% | Add +52.1% | 1,155,651 | $16.2M |
| Ra Capital Management, L.P. | 0.20% | Reduce -51.5% | 1,093,477 | $15.3M |
| Candriam S.C.A. | 0.09% | Add +3.5% | 1,087,876 | $15.2M |
| EcoR1 Capital, LLC | 0.51% | No change | 910,000 | $12.7M |
| Morgan Stanley | 0.00% | Reduce -36.1% | 862,137 | $12.1M |
| AXA S.A. | 0.02% | Reduce -0.1% | 553,959 | $7.8M |
| Long Focus Capital Management, LLC | 0.58% | New | 543,092 | $7.6M |
| Principal Financial Group Inc. | 0.00% | Reduce -8.3% | 406,470 | $5.7M |
| Bank of America Corp. | 0.00% | Add +2.1% | 392,859 | $5.5M |
| BlackRock, Inc. | 0.00% | Reduce -12.9% | 365,408 | $5.1M |
| Parkman Healthcare Partners LLC | 0.66% | Reduce -20.9% | 352,481 | $4.9M |
| Platinum Investment Management Ltd. | 0.25% | Add +13.6% | 309,059 | $4.3M |
| Verition Fund Management LLC | 0.02% | Add +32.1% | 280,327 | $3.9M |
| Renaissance Technologies | 0.01% | Reduce -1.1% | 269,500 | $3.8M |
| Palo Alto Investors LP | 0.54% | Add +317.8% | 248,934 | $3.5M |
| Pinnacle Associates Ltd. | 0.04% | New | 226,742 | $3.2M |
| Aquilo Capital Management, LLC | 5.32% | Add +22.0% | 221,911 | $3.1M |
| TD Asset Management Inc | 0.00% | Reduce -2.4% | 216,016 | $3.0M |
| Handelsbanken Fonder AB | 0.01% | Reduce -1.3% | 215,900 | $3.0M |
| Perceptive Advisors LLC | 0.08% | Reduce -23.0% | 197,108 | $2.8M |
| Millennium Management | 0.00% | New | 176,757 | $2.5M |
| Caption Management, LLC | 0.09% | New | 163,076 | $2.3M |
| Citadel Advisors | 0.00% | Add +40.4% | 144,230 | $2.0M |
| Legal & General Group Plc | 0.00% | Reduce -41.8% | 139,075 | $1.9M |
| Silvercrest Asset Management Group LLC | 0.01% | Reduce -1.0% | 137,740 | $1.9M |
| UBS Group AG | 0.00% | Add +997.0% | 132,361 | $1.9M |
| Harbor Capital Advisors, Inc. | 0.08% | Reduce -1.6% | 131,505 | $1.8M |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -4.0% | 124,497 | $1.7M |
| HighVista Strategies LLC | 0.65% | Reduce -10.8% | 124,430 | $1.7M |
| DAFNA Capital Management LLC | 0.43% | Reduce -1.1% | 120,799 | $1.7M |
| Springhill Fund Asset Management (HK) Co Ltd | 2.65% | — | 116,400 | $1.6M |
| State Street Corp. | 0.00% | Add +1.7% | 87,765 | $1.2M |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0.03% | Add +123.0% | 80,236 | $1.1M |
| Nan Fung Group Holdings Ltd | 0.83% | Add +118.3% | 68,943 | $965K |
| Cubist Systematic Strategies, LLC | 0.01% | Reduce -36.5% | 49,899 | $699K |
| Voya Investment Management LLC | 0.00% | Reduce -54.0% | 48,420 | $678K |
| EntryPoint Capital, LLC | 0.26% | New | 43,873 | $614K |
| Skandinaviska Enskilda Banken AB (publ) | 0.00% | No change | 42,729 | $603K |
| Schonfeld Strategic Advisors LLC | 0.00% | Reduce -90.0% | 42,500 | $595K |
| Altium Capital Management LLC | 0.18% | Reduce -52.5% | 40,352 | $565K |
| Geode Capital Management, LLC | 0.00% | Add +1.3% | 38,815 | $543K |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 30,000 | $414K |
| Woodstock Corp. | 0.03% | No change | 24,981 | $350K |
| Allianz Asset Management GmbH | 0.00% | No change | 24,600 | $344K |
| Jane Street Group, LLC | 0.00% | Add +18.9% | 23,991 | $336K |
| Wexford Capital LP | 0.06% | Reduce -48.7% | 17,879 | $250K |
| Tocqueville Asset Management L.P. | 0.00% | Reduce -4.5% | 14,700 | $206K |
| Erste Asset Management GmbH | 0.00% | No change | 14,000 | $204K |
| Horizon Kinetics Asset Management LLC | 0.00% | Add +4.4% | 14,396 | $202K |
| PNC Financial Services Group, Inc. | 0.00% | No change | 12,900 | $181K |
| Crossmark Global Holdings, Inc. | 0.00% | Add +0.1% | 11,378 | $159K |
| Royal Bank of Canada | 0.00% | Add +2010.8% | 9,773 | $137K |
| China Universal Asset Management Co., Ltd. | 0.01% | Add +30.7% | 9,329 | $131K |
| JPMorgan Chase & Co. | 0.00% | Reduce -8.5% | 7,707 | $108K |
| Exchange Traded Concepts, LLC | 0.00% | No change | 6,707 | $94K |
| Deutsche Bank AG | 0.00% | Reduce -20.5% | 6,417 | $90K |
| HighMark Wealth Management LLC | 0.04% | No change | 4,435 | $62K |
| Avior Wealth Management, LLC | 0.00% | New | 4,043 | $57K |
| Virtus Advisers, LLC | 0.02% | Reduce -6.7% | 3,535 | $49K |
| Barclays PLC | 0.00% | Add +878.3% | 2,612 | $37K |
| Natixis | 0.00% | Reduce -16.0% | 2,298 | $33K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +9.2% | 1,466 | $21K |
| Assetmark, Inc. | 0.00% | Reduce -17.1% | 1,260 | $18K |
| Rhumbline Advisers | 0.00% | Add +5.2% | 1,157 | $16K |
| Coppell Advisory Solutions LLC | 0.00% | No change | 1,076 | $15K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +47.1% | 925 | $13K |
| GF Fund Management Co. LTD. | 0.00% | — | 924 | $13K |
| GAMMA Investing LLC | 0.00% | Reduce -54.7% | 917 | $13K |
| Osaic Holdings, Inc. | 0.00% | Reduce -27.1% | 760 | $11K |
| BNP Paribas Financial Markets | 0.00% | Reduce -14.8% | 680 | $10K |
| Citigroup Inc. | 0.00% | Reduce -5.7% | 630 | $9K |
| Manchester Capital Management LLC | 0.00% | No change | 590 | $8K |
| Group One Trading LLC | 0.00% | New | 466 | $7K |
| FMR LLC | 0.00% | Reduce -99.8% | 316 | $4K |
| R Squared Ltd | 0.00% | — | 180 | $3K |
| Winch Advisory Services, LLC | 0.00% | No change | 172 | $2K |
| Jones Financial Companies LLLP | 0.00% | Add +50.0% | 150 | $2K |
| Caitong International Asset Management Co., Ltd | 0.00% | — | 148 | $2K |
| AdvisorNet Financial, Inc | 0.00% | New | 100 | $1K |
| TD Waterhouse Canada Inc. | 0.00% | New | 100 | $1K |
| Daiwa Securities Group Inc. | 0.00% | No change | 103 | $1K |
| Federation des caisses Desjardins du Quebec | 0.00% | No change | 61 | $854 |
| EverSource Wealth Advisors, LLC | 0.00% | Add +20.0% | 24 | $336 |
| Bell Investment Advisors, Inc | 0.00% | No change | 22 | $308 |
| Caitlin John, LLC | 0.00% | No change | 14 | $196 |
| Blue Trust, Inc. | 0.00% | Reduce -97.9% | 11 | $154 |
| Steward Partners Investment Advisory, LLC | 0.00% | New | 10 | $140 |
| SBI Securities Co., Ltd. | 0.00% | — | 7 | $98 |
"% of holder's portfolio" is BCYC's weight in each manager's 13F, not the share of Bicycle Therapeutics PLC-ADR the manager owns.