Bicycle Therapeutics PLC-ADRBCYC
13F holders, Q1 2026 (March 31)At the end of Q1 2026, 98 institutions reported holding Bicycle Therapeutics PLC-ADR (BCYC) in their 13F filings, down 11 from Q4 2025. 15 opened new positions and 25 sold out. The largest holders were Baker Bros. Advisors LP ($50.5M), FCPM III Services B.V. ($16.1M) and Armistice Capital, LLC ($15.8M). 4 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Steve Cohen (0.0% of Point72 Asset Management's portfolio).
- Company
- Bicycle Therapeutics PLC-ADR
- CUSIP
- 088786108
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 15 | $6.3M |
| Exits | 25 | $40.9M |
All 13F filers, Q4 2025 → Q1 2026: 5,198,151 shares bought and 6,765,566 shares sold, net −1,567,415 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 98 holders
| Baker Bros. Advisors LP | 0.29% | No change | 10,885,357 | $50.5M |
| FCPM III Services B.V. | 2.23% | No change | 3,468,430 | $16.1M |
| Armistice Capital, LLC | 0.52% | Add +5.0% | 3,398,000 | $15.8M |
| Long Focus Capital Management, LLC | 0.68% | Add +102.7% | 3,310,687 | $15.4M |
| Acadian Asset Management LLC | 0.01% | Add +17.8% | 1,968,025 | $9.1M |
| Siren, L.L.C. | 0.20% | Reduce -22.4% | 1,560,882 | $7.2M |
| GSK plc | 1.18% | No change | 1,529,561 | $7.1M |
| Principal Financial Group Inc. | 0.00% | Add +2.3% | 1,174,625 | $5.5M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -12.3% | 1,028,243 | $4.8M |
| Renaissance Technologies | 0.01% | Add +72.8% | 979,300 | $4.5M |
| Morgan Stanley | 0.00% | Add +32.9% | 618,327 | $2.9M |
| Schroder Investment Management Group | 0.00% | Add +5.3% | 615,833 | $2.7M |
| Diadema Partners LP | 0.91% | New | 476,424 | $2.2M |
| Birchview Capital, LP | 1.22% | Add +0.2% | 463,599 | $2.2M |
| Silvercrest Asset Management Group LLC | 0.01% | Reduce -10.1% | 428,684 | $2.0M |
| Marshall Wace, LLP | 0.00% | Add +872.6% | 377,335 | $1.8M |
| Citadel Advisors | 0.00% | Add +39.0% | 377,085 | $1.7M |
| Qube Research & Technologies Ltd | 0.00% | New | 308,617 | $1.4M |
| Millennium Management | 0.00% | Reduce -13.1% | 283,986 | $1.3M |
| BlackRock, Inc. | 0.00% | Reduce -16.2% | 278,992 | $1.3M |
| Moore Capital Management, LP | 0.05% | No change | 275,000 | $1.3M |
| Rangeley Capital, LLC | 1.17% | Add +76.0% | 232,260 | $1.1M |
| Jane Street Group, LLC | 0.00% | Add +245.2% | 218,115 | $1.0M |
| Palo Alto Investors LP | 0.14% | Reduce -8.7% | 201,890 | $937K |
| Eversept Partners, LP | 0.06% | Add +6.6% | 190,715 | $885K |
| Pinnacle Associates Ltd. | 0.01% | Reduce -2.7% | 185,410 | $860K |
| Platinum Investment Management Ltd. | 0.22% | No change | 184,603 | $857K |
| Flax Pond Capital, LLC | 0.66% | Add +1.4% | 176,136 | $817K |
| Two Sigma Investments, LP | 0.00% | Add +24.8% | 164,800 | $765K |
| Point72 Asset Management | 0.00% | Add +69.9% | 130,422 | $605K |
| Manufacturers Life Insurance Company, The | 0.00% | No change | 127,863 | $593K |
| Persistent Asset Partners Ltd | 0.22% | New | 120,437 | $559K |
| Peapod Lane Capital LLC | 0.45% | New | 121,106 | $550K |
| Marex Group Ltd | 0.01% | Add +46.7% | 115,000 | $534K |
| Goldman Sachs Group Inc. | 0.00% | Add +345.4% | 110,147 | $511K |
| XTX Topco Ltd | 0.01% | Add +123.2% | 106,392 | $494K |
| TD Asset Management Inc | 0.00% | Reduce -37.8% | 91,992 | $427K |
| ADAR1 Capital Management, LLC | 0.02% | New | 71,298 | $331K |
| DAFNA Capital Management LLC | 0.07% | No change | 64,492 | $299K |
| EntryPoint Capital, LLC | 0.09% | New | 63,906 | $297K |
| Man Group plc | 0.00% | Add +47.7% | 63,305 | $294K |
| Axq Capital, LP | 0.04% | New | 63,134 | $293K |
| State of Tennessee, Department of Treasury | 0.00% | No change | 61,153 | $284K |
| Sei Investments Co. | 0.00% | Add +7.6% | 52,784 | $245K |
| Jump Financial, LLC | 0.00% | Add +69.5% | 52,544 | $244K |
| HRT Financial LP | 0.00% | New | 45,915 | $213K |
| Alps Advisors Inc. | 0.00% | Reduce -0.8% | 40,651 | $189K |
| Susquehanna International Group, LLP | 0.00% | Reduce -65.1% | 37,888 | $176K |
| Virtus Investment Advisers, LLC | 0.05% | Add +2.5% | 36,601 | $170K |
| Engineers Gate Manager LP | 0.00% | Add +47.2% | 35,400 | $164K |
| UBS Group AG | 0.00% | Add +25.3% | 32,159 | $149K |
| State Street Corp. | 0.00% | Reduce -56.5% | 30,512 | $142K |
| Woodstock Corp. | 0.01% | No change | 29,146 | $135K |
| Gsa Capital Partners LLP | 0.01% | New | 26,842 | $125K |
| Aquatic Capital Management LLC | 0.00% | Add +39.0% | 26,160 | $121K |
| Geode Capital Management, LLC | 0.00% | No change | 25,129 | $117K |
| R Squared Ltd | 0.05% | New | 21,057 | $98K |
| State of New Jersey Common Pension Fund D | 0.00% | No change | 20,105 | $93K |
| Vontobel Holding Ltd. | 0.00% | Add +100.0% | 20,000 | $93K |
| Invesco Ltd. | 0.00% | Add +49.3% | 15,067 | $70K |
| Portland Investment Counsel Inc. | 0.02% | No change | 15,000 | $70K |
| Stifel Financial Corp. | 0.00% | New | 14,687 | $68K |
| Royal Bank of Canada | 0.00% | Add +35.5% | 14,470 | $67K |
| Forefront Analytics, LLC | 0.06% | Add +7.7% | 14,394 | $67K |
| Federation des caisses Desjardins du Quebec | 0.00% | No change | 14,302 | $67K |
| 49 Wealth Management, LLC | 0.01% | New | 14,317 | $66K |
| Cerity Partners LLC | 0.00% | Add +1.6% | 13,570 | $63K |
| Horizon Kinetics Asset Management LLC | 0.00% | Reduce -4.4% | 13,188 | $61K |
| Erste Asset Management GmbH | 0.00% | No change | 14,000 | $61K |
| Rhumbline Advisers | 0.00% | Add +12.5% | 12,571 | $58K |
| Crossmark Global Holdings, Inc. | 0.00% | Add +0.1% | 11,408 | $53K |
| Pinnacle Wealth Management Advisory Group, LLC | 0.00% | Add +9.8% | 10,985 | $51K |
| Two Sigma Securities, LLC | 0.01% | New | 10,879 | $50K |
| Commonwealth of Pennsylvania Public School Empls Retrmt SYS | 0.00% | No change | 10,116 | $47K |
| JPMorgan Chase & Co. | 0.00% | Reduce -46.2% | 9,873 | $43K |
| Legal & General Group Plc | 0.00% | No change | 9,054 | $39K |
| China Universal Asset Management Co., Ltd. | 0.00% | Add +9.1% | 8,222 | $38K |
| FNY Investment Advisers, LLC | 0.02% | Add +0.9% | 7,557 | $35K |
| Natixis | 0.00% | No change | 4,645 | $21K |
| Assetmark, Inc. | 0.00% | Add +16.3% | 4,218 | $20K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +7.5% | 2,417 | $11K |
| Barclays PLC | 0.00% | Add +319.4% | 2,357 | $11K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +17.9% | 1,966 | $9K |
| Citigroup Inc. | 0.00% | Add +0.3% | 1,295 | $6K |
| GAMMA Investing LLC | 0.00% | Reduce -9.3% | 1,257 | $6K |
| GF Fund Management Co. LTD. | 0.00% | Add +13.5% | 1,032 | $5K |
| BNP Paribas Financial Markets | 0.00% | Reduce -9.0% | 1,016 | $5K |
| Jones Financial Companies LLLP | 0.00% | Add +100.0% | 500 | $2K |
| HighMark Wealth Management LLC | 0.00% | No change | 435 | $2K |
| Wells Fargo & Company | 0.00% | No change | 200 | $928 |
| Winch Advisory Services, LLC | 0.00% | No change | 172 | $798 |
| Basecamp Wealth Advisors LLC | 0.00% | No change | 167 | $775 |
| Osaic Holdings, Inc. | 0.00% | New | 10 | $46 |
| Fideuram - Intesa Sanpaolo Private Banking S.P.A. | 0.00% | Reduce -100.0% | 9 | $42 |
| SBI Securities Co., Ltd. | 0.00% | No change | 6 | $28 |
| Rockefeller Capital Management L.P. | 0.00% | No change | 5 | $23 |
| Caitlin John, LLC | 0.00% | No change | 2 | $9 |
| Caitong International Asset Management Co., Ltd | 0.00% | New | 1 | $5 |
"% of holder's portfolio" is BCYC's weight in each manager's 13F, not the share of Bicycle Therapeutics PLC-ADR the manager owns.