Bicycle Therapeutics PLC-ADRBCYC

13F holders, Q2 2025 (June 30)
110holders +15
29new positions
13sold out
4famous investors
$6.95avg. 13F price*

At the end of Q2 2025, 110 institutions reported holding Bicycle Therapeutics PLC-ADR (BCYC) in their 13F filings, up 15 from Q1 2025. 29 opened new positions and 13 sold out. The largest holders were Baker Bros. Advisors LP ($75.7M), FCPM III Services B.V. ($24.0M) and Armistice Capital, LLC ($19.5M). 4 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).

Company
Bicycle Therapeutics PLC-ADR
CUSIP
088786108
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150 Q1 2024: 95Q1 2024Q2 2024: 107Q2 2024Q3 2024: 105Q3 2024Q4 2024: 97Q4 2024Q1 2025: 95Q1 2025Q2 2025: 110Q2 2025Q3 2025: 99Q3 2025Q4 2025: 109Q4 2025Q1 2026: 98Q1 2026Q2 2026: 103Q2 2026

Total Exit/New Position Q1 2025 → Q2 2025

InstitutionsTotal Value
New Positions29$7.0M
Exits13$18.8M

All 13F filers, Q1 2025 → Q2 2025: 4,546,943 shares bought and 4,910,127 shares sold, net −363,184 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 110 holders

Baker Bros. Advisors LP 0.73% No change 10,885,357 $75.7M
FCPM III Services B.V. 6.50% No change 3,452,330 $24.0M
Armistice Capital, LLC 0.74% Add +4.8% 2,800,000 $19.5M
Westfield Capital Management Co. LP 0.08% Add +4.6% 2,780,491 $19.3M
Siren, L.L.C. 0.72% Add +11.0% 2,012,752 $14.0M
Point72 Asset Management 0.03% Reduce -52.0% 1,772,600 $12.3M
T. Rowe Price Associates Inc. 0.00% Reduce -4.4% 1,468,393 $10.2M
Millennium Management 0.01% Add +218.4% 1,443,619 $10.0M
Long Focus Capital Management, LLC 0.59% Add +1.8% 1,317,293 $9.2M
Deep Track Capital, LP 0.27% Add +56.9% 1,203,244 $8.4M
Candriam S.C.A. 0.05% Reduce -2.7% 1,172,387 $8.1M
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.02% Reduce -14.6% 1,041,456 $7.2M
Morgan Stanley 0.00% Add +3.7% 1,037,153 $7.2M
Tybourne Capital Management (hk) Ltd. 20.00% Add +72.4% 993,743 $6.9M
Bank of America Corp. 0.00% Add +47.4% 830,634 $5.8M
Principal Financial Group Inc. 0.00% Add +10.5% 697,267 $4.8M
Acadian Asset Management LLC 0.01% Add +454.1% 698,501 $4.8M
Jefferies Financial Group Inc. 0.06% Add +12.8% 461,100 $3.2M
Woodline Partners LP 0.01% Reduce -0.4% 362,325 $2.5M
Renaissance Technologies 0.00% Add +5.6% 318,400 $2.2M
Platinum Investment Management Ltd. 0.13% Reduce -0.8% 285,381 $2.0M
AXA S.A. 0.01% Reduce -49.4% 280,152 $1.9M
Silvercrest Asset Management Group LLC 0.01% No change 265,693 $1.8M
BlackRock, Inc. 0.00% Reduce -18.1% 264,348 $1.8M
Palo Alto Investors LP 0.37% No change 248,934 $1.7M
Eversept Partners, LP 0.15% New 211,469 $1.5M
Handelsbanken Fonder AB 0.00% Reduce -7.4% 200,000 $1.4M
TD Asset Management Inc 0.00% No change 193,092 $1.3M
Legal & General Group Plc 0.00% Add +28.9% 174,910 $1.2M
Pinnacle Associates Ltd. 0.02% Reduce -19.8% 171,953 $1.2M
OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.03% Reduce -3.3% 143,800 $999K
Manufacturers Life Insurance Company, The 0.00% Add +1.6% 140,492 $976K
Citadel Advisors 0.00% Add +7.2% 139,467 $969K
Harbor Capital Advisors, Inc. 0.04% Reduce -6.4% 138,661 $964K
Janney Montgomery Scott LLC 0.00% New 100,291 $697K
Soleus Capital Management, L.P. 0.05% New 100,000 $695K
Cubist Systematic Strategies, LLC 0.01% Add +85.7% 87,717 $610K
Monimus Capital Management, LP 0.48% New 85,224 $592K
Rangeley Capital, LLC 0.68% New 75,000 $521K
Moore Capital Management, LP 0.01% Add +50.0% 75,000 $521K
Two Sigma Advisers, LP 0.00% New 70,200 $488K
Nan Fung Group Holdings Ltd 0.76% No change 68,943 $479K
State Street Corp. 0.00% Reduce -22.9% 65,997 $459K
DAFNA Capital Management LLC 0.13% Reduce -20.2% 64,492 $448K
Two Sigma Investments, LP 0.00% New 56,198 $391K
Goldman Sachs Group Inc. 0.00% Add +107.5% 52,265 $363K
Dynamic Technology Lab Private Ltd 0.04% New 45,950 $320K
Skandinaviska Enskilda Banken AB (publ) 0.00% No change 42,729 $297K
Geode Capital Management, LLC 0.00% Add +89.0% 40,412 $281K
Paloma Partners Management Co 0.12% New 39,250 $273K
UBS Group AG 0.00% Reduce -54.1% 33,375 $232K
DekaBank Deutsche Girozentrale 0.00% No change 30,000 $211K
Man Group plc 0.00% New 28,675 $199K
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% Add +435.3% 27,300 $190K
Susquehanna International Group, LLP 0.00% New 26,567 $185K
Alps Advisors Inc. 0.00% New 25,757 $179K
Woodstock Corp. 0.02% Reduce -4.2% 23,927 $166K
Tocqueville Asset Management L.P. 0.00% Add +25.1% 22,900 $159K
Jane Street Group, LLC 0.00% New 22,607 $157K
Quadrature Capital Ltd 0.00% New 17,738 $123K
Jump Financial, LLC 0.00% New 16,740 $116K
Portland Investment Counsel Inc. 0.03% No change 15,000 $109K
Engineers Gate Manager LP 0.00% New 15,402 $107K
Erste Asset Management GmbH 0.00% No change 14,000 $101K
State of Tennessee, Department of Treasury 0.00% New 14,382 $100K
Cerity Partners LLC 0.00% Add +7.5% 14,350 $100K
Horizon Kinetics Asset Management LLC 0.00% Reduce -4.2% 13,792 $96K
Graham Capital Management, L.P. 0.00% New 13,102 $91K
PNC Financial Services Group, Inc. 0.00% No change 13,080 $91K
Ameriprise Financial Inc. 0.00% New 12,304 $86K
Squarepoint Ops LLC 0.00% New 11,874 $83K
Crossmark Global Holdings, Inc. 0.00% Reduce -0.1% 11,389 $79K
Virtus Investment Advisers, LLC 0.03% Add +32.6% 10,821 $75K
Sei Investments Co. 0.00% No change 10,637 $74K
Royal Bank of Canada 0.00% Reduce -42.2% 10,362 $72K
Ausdal Financial Partners, Inc. 0.00% New 10,000 $70K
Federation des caisses Desjardins du Quebec 0.00% Add +15642.6% 9,603 $67K
China Universal Asset Management Co., Ltd. 0.01% Add +0.4% 8,866 $62K
JPMorgan Chase & Co. 0.00% Add +8.4% 7,637 $53K
Tower Research Capital LLC (TRC) 0.00% Add +284.7% 4,159 $29K
Barclays PLC 0.00% Add +5.1% 3,476 $24K
Rhumbline Advisers 0.00% Add +130.4% 3,005 $21K
Assetmark, Inc. 0.00% Add +61.7% 2,073 $14K
Natixis 0.00% Reduce -8.4% 1,947 $14K
Raymond James Financial Inc. 0.00% New 1,933 $13K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +16.5% 1,705 $12K
Caitong International Asset Management Co., Ltd 0.01% Add +75750.0% 1,517 $11K
GAMMA Investing LLC 0.00% Add +40.6% 1,488 $10K
Clearstead Advisors, LLC 0.00% New 1,393 $10K
Group One Trading LLC 0.00% Add +679.5% 1,294 $9K
Simplex Trading, LLC 0.00% Add +117.3% 1,241 $8K
GF Fund Management Co. LTD. 0.00% No change 1,126 $8K
Brooklyn Investment Group 0.00% New 923 $6K
Citigroup Inc. 0.00% Add +32.5% 913 $6K
Manchester Capital Management LLC 0.00% No change 590 $4K
BNP Paribas Financial Markets 0.00% Reduce -56.2% 530 $4K
HighMark Wealth Management LLC 0.00% No change 435 $3K
FMR LLC 0.00% No change 316 $2K
Jones Financial Companies LLLP 0.00% No change 250 $2K
Wells Fargo & Company 0.00% New 200 $1K
Winch Advisory Services, LLC 0.00% No change 172 $1K
Toth Financial Advisory Corp. 0.00% New 150 $1K
Daiwa Securities Group Inc. 0.00% No change 103 $1K
TD Waterhouse Canada Inc. 0.00% No change 100 $699
Walleye Capital LLC 0.00% New 39 $271
CIBC Private Wealth Group LLC 0.00% New 23 $160
Principal Securities, Inc. 0.00% New 18 $125
Osaic Holdings, Inc. 0.00% No change 18 $125
Blue Trust, Inc. 0.00% No change 11 $76
SBI Securities Co., Ltd. 0.00% No change 6 $42

"% of holder's portfolio" is BCYC's weight in each manager's 13F, not the share of Bicycle Therapeutics PLC-ADR the manager owns.