Cue BiopharmaCUE

13F holders, Q4 2025 (December 31)
49holders −3
6new positions
11sold out
1famous investor
$0.31avg. 13F price*

At the end of Q4 2025, 49 institutions reported holding Cue Biopharma Inc. (CUE) in their 13F filings, down 3 from Q3 2025. 6 opened new positions and 11 sold out. The largest holders were Bleichroeder LP ($2.1M), GC Wealth Management RIA, LLC ($1.4M) and Vanguard Group Inc. ($919K). One famous investor held it Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).

Company
Cue Biopharma Inc.
CUSIP
22978P106
Latest filing quarter
Q2 2026

History

Number of 13F holders

020406080 Q1 2024: 77Q1 2024Q2 2024: 75Q2 2024Q3 2024: 50Q3 2024Q4 2024: 55Q4 2024Q1 2025: 49Q1 2025Q2 2025: 47Q2 2025Q3 2025: 52Q3 2025Q4 2025: 49Q4 2025Q1 2026: 55Q1 2026Q2 2026: 1Q2 2026

Total Exit/New Position Q3 2025 → Q4 2025

InstitutionsTotal Value
New Positions6$705K
Exits11$138K

All 13F filers, Q3 2025 → Q4 2025: 4,267,676 shares bought and 538,440 shares sold, net +3,729,236 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 49 holders

Bleichroeder LP 0.37% No change 6,819,164 $2.1M
GC Wealth Management RIA, LLC 0.05% Add +35.0% 4,631,644 $1.4M
Vanguard Group Inc. 0.00% Reduce -0.8% 3,014,034 $919K
Lion Point Capital, LP 3.48% New 2,202,854 $673K
Geode Capital Management, LLC 0.00% Add +0.3% 803,291 $245K
Boothbay Fund Management, LLC 0.01% Add +15.3% 704,297 $215K
Robertson Stephens Wealth Management, LLC 0.00% No change 478,500 $146K
BlackRock, Inc. 0.00% No change 449,162 $137K
Texas Capital Bank Wealth Management Services Inc 0.01% Add +1231.3% 440,670 $135K
Angeles Wealth Management, LLC 0.01% Add +158.3% 310,000 $95K
Advisory Research Inc. 0.01% No change 257,225 $79K
Stifel Financial Corp. 0.00% Add +25.4% 246,556 $75K
Renaissance Technologies 0.00% Add +5.0% 238,354 $73K
Bank of America Corp. 0.00% Reduce -36.0% 207,569 $63K
State Street Corp. 0.00% Reduce -5.5% 179,353 $55K
Susquehanna International Group, LLP 0.00% Add +1.4% 168,829 $52K
Chicago Partners Investment Group LLC 0.00% No change 85,937 $33K
Northern Trust Corp. 0.00% No change 100,958 $31K
Northwestern Mutual Wealth Management Co. 0.00% No change 79,500 $24K
Jane Street Group, LLC 0.00% New 69,793 $21K
UBS Group AG 0.00% Reduce -76.5% 46,848 $14K
LPL Financial LLC 0.00% No change 46,390 $14K
Sigma Planning Corp 0.00% Reduce -23.0% 41,050 $13K
Miramontes Capital, LLC 0.00% — 26,041 $8K
NewEdge Advisors, LLC 0.00% No change 20,000 $6K
Cambridge Investment Research Advisors, Inc. 0.00% No change 20,000 $6K
HRT Financial LP 0.00% New 20,863 $6K
Prevail Innovative Wealth Advisors, LLC 0.00% No change 18,987 $6K
Morgan Stanley 0.00% Reduce -32.4% 18,594 $6K
Goldman Sachs Group Inc. 0.00% Reduce -0.1% 14,371 $4K
SeaCrest Wealth Management, LLC 0.00% No change 10,000 $4K
HighTower Advisors, LLC 0.00% New 10,929 $3K
Barclays PLC 0.00% No change 6,029 $2K
Gleason Group, Inc. 0.00% No change 6,000 $2K
New Millennium Group LLC 0.00% New 5,750 $2K
NFSG Corp 0.00% No change 3,000 $916
Wells Fargo & Company 0.00% Reduce -86.9% 2,563 $783
Simplex Trading, LLC 0.00% Reduce -47.1% 2,557 $780
Golden State Wealth Management, LLC 0.00% No change 2,000 $611
Tidemark, LLC 0.00% No change 1,500 $458
Physician Wealth Advisors, Inc. 0.00% No change 1,006 $308
Osaic Holdings, Inc. 0.00% No change 680 $209
BNP Paribas Financial Markets 0.00% Reduce -39.9% 415 $127
Jones Financial Companies LLLP 0.00% New 400 $122
MAI Capital Management 0.00% No change 350 $107
Torren Management, LLC 0.00% — 324 $99
Armstrong Advisory Group, Inc. 0.00% No change 120 $37
IFP Advisors, Inc 0.00% No change 100 $31
JPMorgan Chase & Co. 0.00% Reduce -99.6% 4 $1

"% of holder's portfolio" is CUE's weight in each manager's 13F, not the share of Cue Biopharma Inc. the manager owns.